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World Journal of Traditional Chinese Medicine 2020年第2期6卷 196-202页

作者： Yu-Ting Ma Qiu-Yun Wu Sheng-Bo Lu Wen-Mei Qiu Pan Pan Min Xu nong tang Department of Traditional Chinese Medicine The Fourth People’s Hospital of Nanning(Guangxi AIDS Clinical Treatment Center)Nanning School of Chinese Medicine Hong Kong Baptist UniversityKowloon TongHong Kong The President of Guangxi University of Traditional Chinese Medicine NanningChina

This paper is a discussion of Professor tang nong’s approach to the diagnosis and treatment of the coronavirus disease 2019(COVID-19)while providing a case report at the *** tang nong considered that the main etiologies of the disease are"cold,wet,and poisonous."He suggested resolving the body’s dampness by balancing internal organ functions,detoxifying the lungs,and providing ***,the treatment of cold with herbs and cleansing heat must not be performed too early to prevent the spread of the *** principles from the basic theory of Fuyang Pai from traditional Chinese medicine(TCM),this project used the Huashi Qingfei immune formula(modified Guizhi Erchen decoction),which has been shown to be effective,to treat patients diagnosed with *** present,the participation of TCM in our hospital is over 96%with a cure rate of approximately 90%.

关键词： Fuyang Guizhi method novel coronavirus pneumonia traditional Chinese medicine

Etching-free pixel definition in InGaN green micro-LEDs

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Light(Science & Applications) 2024年第8期13卷 1655-1665页

作者： Zhiyuan Liu Yi Lu Haicheng Cao Glen Isaac Maciel Garcia Tingang Liu Xiao tang Na Xiao Raul Aguileta Vazquez Mingtao nong Xiaohang Li Advanced Semiconductor Laboratory Electrical and Computer Engineering ProgramCEMSE DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia

The traditional plasma etching process for defining micro-LED pixels could lead to significant sidewall *** near sidewall regions act as non-radiative recombination centers and paths for current leakage,significantly deteriorating device *** this study,we demonstrated a novel selective thermal oxidation(STO)method that allowed pixel definition without undergoing plasma damage and subsequent dielectric *** annealing in ambient air oxidized and reshaped the LED structure,such as p-layers and InGaN/GaN multiple quantum ***,the pixel areas beneath the pre-deposited SiO_(2)layer were selectively and effectively *** was demonstrated that prolonged thermal annealing time enhanced the insulating properties of the oxide,significantly reducing LED leakage ***,applying a thicker SiO_(2)protective layer minimized device resistance and boosted device efficiency *** the STO method,InGaN green micro-LED arrays with 50-,30-,and 10-μm pixel sizes were manufactured and *** results indicated that after 4 h of air annealing and with a 3.5-μm SiO_(2)protective layer,the 10-μm pixel array exhibited leakage currents density 1.2×10^(-6)A/cm^(2)at-10 V voltage and a peak on-wafer external quantum efficiency of~6.48%.This work suggests that the STO method could become an effective approach for future micro-LED manufacturing to mitigate adverse LED efficiency size effects due to the plasma etching and improve device ***-LEDs fabricated through the STO method can be applied to micro-displays,visible light communication,and optical interconnect-based *** planar pixel geometry will provide more possibilities for the monolithic integration of driving circuits with ***,the STO method is not limited to micro-LED fabrication and can be extended to design other III-nitride devices,such as photodetectors,laser diodes,high-electron-mobility transistors

关键词： annealing protective quantum

论人体内阳外阴本体结构理论与扶阳学派核心思想的贯通

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中医杂志 2017年第23期58卷 1981-1984页

作者：唐农广西中医药大学

扶阳学派从乾坤坎离卦象的分析入手,以坎离中立极之阴阳为纲纪贯穿其理论与临证的始终,并使"生命以火立极"诸观点成为必然推论。人体内阳外阴本体结构论则以阴阳运动的本质属性为线索,以《周易》《黄帝内经》相关论述为支持,提出关于人... 详细信息

扶阳学派从乾坤坎离卦象的分析入手,以坎离中立极之阴阳为纲纪贯穿其理论与临证的始终,并使"生命以火立极"诸观点成为必然推论。人体内阳外阴本体结构论则以阴阳运动的本质属性为线索,以《周易》《黄帝内经》相关论述为支持,提出关于人体阴阳体用关系、正邪定位与辨证论治的新认识。通过分析发现,扶阳学派和阴阳本体结构论在基本观点的认识上是贯通的,都认为人体阴阳的气化运动的一般规律为阳是自下而上、自内而外,阴是自上而下、自外而内形成交感的,从而澄清了目前中医学界在人体阴阳交感运动中认为阳在外而阴在内的模糊认识。

关键词：阴阳本体结构内阳外阴扶阳学派立极阴阳

Meta-analysis for efficacy of modified Zhenwu Decoction combined with westernmedicine in treatment of heart failure

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TMR Integrative Medicine 2017年第3期1卷 86-98页

作者： Qiu-Lan Mo Lin Lin nong tang Lv-Xing Qin Pan Zheng Guangxi University of Chinese Medicine Nanning China The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China

Objective： To carry out a systematic evaluation of the efficacy of modified Zhenwu Decoction combined withwestern medicine in the treatment of heart failure. Methods： Literature was retrieved in China KnowledgeResource Integrated Database （CNKI）, Chinese scientific journal database （VIP）, Wanfang Data Resource System（WANFANG DATA）, PubMed and other traditional Chinese medicine related periodicals by retrieval methods ofsubject terms combined with free words and computer retrieval combined with manual retrieval. Literature wasscreened strictly according to the inclusion *** quality of the included literature was evaluated according tothe quality standard of Jadad scale and Cochrane collaboration network bias risk assessment tool. The literaturedata was extracted. RevMan5.3 software was used to analyze data and the curative effect of modified ZhenwuDecoction combined with western medicine was objectively evaluated. Results： The response rate of theexperimental group was better than that of the control group [OR = 3.69,95% IC （2.36,5.79）]. The value of EF inthe experimental group was higher than that in the control group after treatment [MD = 5.85, 95% IC （3.90, 7.79） ].The Lee, score of the experimental group was lower than that of the control group after treatment [MD = -1.37,95% IC （-2.23, -0.52） ]. The value of BNP in the experimental group was less than that in the control group aftertreatment [MD = -114.48, 95%IC （-186.28, -42.68）]. The life quality score in the experimental group was less thanthat of the control group after treatment [MD = -8.44, 95%IC （-11.73, -5.15）]. Conclusion： The curative effect ofmodified Zhenwu Decoction combined with western medicine in the treatment of heart failure is better than thesimple western medicine *** modified Zhenwu Decoction combined with western medicine in thetreatment of heart failure is worthy of clinical promotion. However, the results of this study still need further validation by more high quality r

关键词： Modified Zhenwu Decoction Heart Failure Meta-analysis

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基于“阳化气、阴成形”探讨中风的中医证治

中医杂志 2020年第8期61卷 721-723页

作者：张伟唐农湖南中医药大学研究生院湖南省长沙市410208 西南医科大学附属中医医院广西中医药大学

基于"阳化气,阴成形"理论总结中风的发病机制及治疗思路。认为中风的病机特点为"阳化气,阴成形"功能失司,温阳化气应贯穿于中风治疗全程,治疗中应注重三焦次第治疗,先以疏通中上二焦之桂枝法,再以温固下焦元阳之四逆法为基本治疗大法,... 详细信息

基于"阳化气,阴成形"理论总结中风的发病机制及治疗思路。认为中风的病机特点为"阳化气,阴成形"功能失司,温阳化气应贯穿于中风治疗全程,治疗中应注重三焦次第治疗,先以疏通中上二焦之桂枝法,再以温固下焦元阳之四逆法为基本治疗大法,如此则阳化气之用恢复,阳气密固可行,则疗效可期。

关键词：中风阳化气,阴成形温阳化气次第治疗

Process Optimization and Content Determination of Total Flavonoids of Zhuang Medicine Clerodendrum japonicum(Thumb.)Sweet

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Medicinal Plant 2020年第4期11卷 44-47,53页

作者： Jiangcun WEI Zujie QIN Yunli tang nong tang Liping QIN Yan MA Mingchan WEI Fengxian ZHAO Guangxi International Zhuang Medical Hospital Nanning 530201 China Guangxi Key Laboratory of Basic Research in Traditional Chinese Medicine Guangxi University of Chinese Medicine Nanning 530200 China Guangxi University of Chinese Medicine Nanning 530200 China

[Objectives]To optimize the extraction process of total flavonoids of Zhuang medicine Clerodendrum japonicum(Thumb.)Sweet and establish a method for its extraction and content determination.[Methods]The total flavonoids of *** were extracted by reflux extraction *** a single factor experiment,the effects of extraction method,extraction solvent concentration,extraction volume and extraction time on the total flavonoids content of medicinal materials were investigated to select the optimal extraction process of the total flavonoids of ***.[Results]The optimal extraction process of the total flavonoids of *** was 75%ethanol,1∶20 solid-to-liquid ratio,and 50 min reflux extraction time.[Conclusions]This method can effectively determine the content of total flavonoids in *** and provide a certain scientific basis for the study of the quality standard of this Zhuang *** method has high *** is stable and feasible in extraction of total flavonoids from Zhuang medicine ***.

关键词： Clerodendrum japonicum(Thumb.)Sweet Total flavonoids Extraction process UV-visible spectrophotometry

Dynamic activity of NF-κB in multiple trauma patients and protective effects of ulinastain

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Chinese Journal of Traumatology 2011年第6期14卷 354-358页

作者： LI Jun LI Neng-ping GU Yong-feng YANG Xin LU Xiao-bing CONG Jian-nong LING Yun tang Jiang-an YUAN Xiao-yan WANG Hu Department of General Surgery Shanghai Pudong New Area Gongli Hospital Shanghai 200135China

Objective： To investigate the dynamic activity of NF-κB at the early stage of injury in mul tiple trauma patients and the protective effects of ulinastain. Methods： From January 2008 to May 2010, patients with multiple traumas admitted to our emergency department were enrolled in this study. Their age varied from 20- 55 years. All enrolled patients were assigned randomly into control group （26 cases of multiple injury without ulinastain treatment）, ulinastain group （25 cases of multiple injury with ulinastain treatment）, and mild injury group （20 cases） for basic control. The inclusion criteria for mild injury group were AIS-2005 ≤ 3, single wound, previously healthy inhospital patients without the history of surgical intervention. In addition to routine treatment, patients in ulinastain group were intravenously injected 200 000 IU of ulinastain dissolved in 100 ml of normal saline within 12 hours after injury and subsequently injected at the interval of every 8 hours for 7 days. NF-κB activity in monocytes and the level of TNF- α, IL-1, IL-6 in serum on admission （day 0）, day 1, 2, 3, 4, and 7 were measured. Data were compared and analyzed between different groups. Results： NF-κB activity in monocytes and TNF- α, IL-1 and IL-6 of these patients reached peak levels at 24 hour after trauma, with gradual decrease to normal at 72 hour after trauma. NF-κB activity and levels of TNF- α, IL- 1 and IL-6 were lower in ulinastain group than control one, without any significant difference between the two groups. The mean duration for systemic inflammatory response syndrome and multiple organ dysfunction syndrome was 7 d±3.1 d and 10 d±3.5 d in ulinastain group and control group respectively, and showed a significant difference. Conclusions： NF-κB activity in monocytes and the levels of inflammatory cytokines in multiply injured patients increased transiently at the early stage of trauma. Ulinastain may shorten the duration of systemic inflammatory response syndrome and mult

关键词： Wounds and injuries Multiple trauma NF-kappaB Cytokines

五脏温阳化瘀汤抑制周期蛋白依赖激酶-5过表达对SAMP8小鼠脑神经纤维缠结的影响

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中国实验方剂学杂志 2019年第9期25卷 61-66页

作者：农微卫智权莫雪妮吴林唐农广西中医药大学广西中医基础研究重点实验室南宁530001

目的:探讨五脏温阳化瘀汤改善SAMP8小鼠认知能力的周期蛋白依赖性激酶-5(CDK-5)相关脑神经纤维缠结机制。方法:10只SAMR1小鼠为正常组,40只SAMP8小鼠随机分为模型组,多奈哌齐组(0.4 mg·kg^(-1)·d^(-1)),五脏温阳化瘀汤高、低剂量组(5,... 详细信息

目的:探讨五脏温阳化瘀汤改善SAMP8小鼠认知能力的周期蛋白依赖性激酶-5(CDK-5)相关脑神经纤维缠结机制。方法:10只SAMR1小鼠为正常组,40只SAMP8小鼠随机分为模型组,多奈哌齐组(0.4 mg·kg^(-1)·d^(-1)),五脏温阳化瘀汤高、低剂量组(5,1.25 g·kg^(-1)·d^(-1)),连续灌胃给药4周。Morris水迷宫测试定位航行与空间探索能力;实时荧光定量聚合酶链式反应(Real-time PCR)检测脑神经组织CDK-5 mRNA表达水平;蛋白免疫印迹法(Western blot)检测脑神经组织CDK-5蛋白表达与Tau蛋白磷酸化水平;银染法检测脑神经纤维缠结。结果:与正常组比较,模型组脑神经组织CDK-5与Tau蛋白磷酸化表达水平均显著升高(P<0.01),脑神经纤维缠结明显增多,定位航行与空间探索能力显著减弱(P<0.01);与模型组比较,五脏温阳化瘀汤高、低剂量组脑神经组织CDK-5与Tau蛋白磷酸化表达水平均明显降低(P<0.05,P<0.01),脑神经纤维缠结减少,小鼠定位航行并空间探索能力明显改善(P<0.05,P<0.01)。结论:五脏温阳化瘀汤可显著改善SAMP8小鼠认知能力,可能与其抑制CDK-5过表达进而抑制Tau蛋白过磷酸化导致脑神经纤维缠结减少有关。

关键词：五脏温阳化瘀汤桂枝加附子汤痴呆周期蛋白依赖性激酶-5 (CDK-5) Tau蛋白过磷酸化神经纤维缠结

从人体阴阳本体结构谈谈对《伤寒论》六经实质的认识

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湖南中医药大学学报 2018年第1期38卷 7-12页

作者：唐农广西中医药大学广西南宁530200

本文以人体阴阳本体结构为主线,辅以八纲辨证与标本两端,从《伤寒论》六经病"欲解时"入手,对六经的时相变化以及六经病提纲证与代表方作出了诠释,从而使六经的实质得以阐明,即六经乃是人体一阴一阳在内阳外阴本体结构范围内的不同时区... 详细信息

本文以人体阴阳本体结构为主线,辅以八纲辨证与标本两端,从《伤寒论》六经病"欲解时"入手,对六经的时相变化以及六经病提纲证与代表方作出了诠释,从而使六经的实质得以阐明,即六经乃是人体一阴一阳在内阳外阴本体结构范围内的不同时区的六种不同的气化形式或气化单元,亦称"六经时相"。并认为六经实质能如此直接认定,不需它求,根本在于《伤寒论》六经的提出与人体内阳外阴本体结构遵循着中医理论共同的基本原理,即阴阳运动的一致性与交感性;还在于张仲景将六经阴阳的气化交感运动与阴阳四时的生长收藏变化直接对应起来,而人体阴阳本体结构正是作为如实反映阴阳的四时消息变化的一个定式而提出的,故能两两相契。

关键词：《伤寒论》六经实质内阳外阴本体结构时相

广西医疗卫生资源配置的空间分布及聚集性分析

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中国卫生资源 2017年第2期20卷 114-117页

作者：罗慧农艺唐忠广西医科大学信息与管理学院广西南宁530021

目的:探讨广西县级医疗卫生资源配置的空间分布及聚集性,为卫生资源优化配置提供参考。方法:运用反距离加权(inverse distance weighted,IDW)插值法、Moran’s I空间自相关分析和Getis-Ord Gi*热点分析方法对2014年广西县级医疗卫生资... 详细信息

目的:探讨广西县级医疗卫生资源配置的空间分布及聚集性,为卫生资源优化配置提供参考。方法:运用反距离加权(inverse distance weighted,IDW)插值法、Moran’s I空间自相关分析和Getis-Ord Gi*热点分析方法对2014年广西县级医疗卫生资源配置数据进行空间分析。结果:广西医疗卫生资源在城中区、青秀区、鱼峰区、象山区、右江区周边县(区)配置较高,分别以这些区域为中心向四周辐射降低。空间自相关分析结果表明医疗机构床位配置呈正相关,卫生技术人员和执业(助理)医师配置在总体上无聚集现象,但存在局部医疗卫生资源配置不均衡现象。结论:广西医疗卫生资源配置水平较低,存在空间分布不平衡、城乡差距明显等特点,其中医疗机构床位配置公平性优于医疗卫生人力资源配置。应进一步加大卫生资源投入力度,提高医疗卫生资源配置水平,缩小城乡差距。

关键词：医疗卫生资源空间分布空间聚集性