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Developmental dysplasia of the hip in the newborn: A systematic review

World Journal of Orthopedics 2013年第2期4卷 32-41页

作者： Vivek Gulati Kelechi Eseonu Junaid Sayani nizar Ismail Chika Uzoigwe Muhammed Zaki Choudhury Pooja Gulati Adeel Aqil Saket Tibrewal Department of Orthopaedic Sur-gery Imperial College NHS Trust London W6 8RF United Kingdom Department of Orthopaedic Surgery Leicester Royal Infirmary Infirmary Square Leicester LE1 5WW United Kingdom Department of Orthopaedic Sur-gery Birmingham Healthcare Trust Edgbaston Birmingham B15 2TH United Kingdom London Rheumatology Rotation London W6 8RF United Kingdom

Developmental dysplasia of the hip(DDH) denotes a wide spectrum of conditions ranging from subtle acetabular dysplasia to irreducible hip dislocations. Clinical diagnostic tests complement ultrasound imaging in allowing diagnosis, classification and monitoring of this condition. Classification systems relate to the alpha and beta angles in addition to the dynamic coverage index(DCI). Screening programmes for DDH show considerable geographic variation; certain risk factors have been identified which necessitate ultrasound assessment of the newborn. The treatment of DDH has undergone significant evolution, but the current gold standard is still the Pavlik harness. Duration of Pavlik harness treatment has been reported to range from 3 to 9.3 mo. The beta angle, DCI and the superior/lateral femoral head displacement can be assessed via ultrasound to estimate the likelihood of success. Success rates of between 7% and 99% have been reported when using the harness to treat DDH. Avascular necrosis remains the most devastating complication of harness usage with a reported rate of between 0% and 28%. Alternative non-surgical treatment methods used for DDH include devices proposed by LeD amany, Frejka, Lorenz and Ortolani. The Rosen splint and Wagner stocking have also been used for DDH treatment. Surgical treatment for DDH comprises open reduction alongside a combination of femoral or pelvic osteotomies. Femoral osteotomies are carried out in cases of excessive anteversion or valgus deformity of the femoral neck. The two principal pelvic osteotomies most commonly performed are the Salter osteotomy and Pemberton acetabuloplasty. Serious surgical complications include epiphyseal damage, sciatic nerve damage and femoral neck fracture.

关键词： Developmental dysplasia of the hip Congenital Pavlik harness Ultrasound screening Pelvic osteotomy

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Role of foliar spray of plant growth regulators in improving photosynthetic pigments and metabolites in Plantago ovata (Psyllium) under salt stress–A field appraisal

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BIOCELL 2023年第3期47卷 523-532页

作者： ABDUL SAMAD KANVAL SHAUKAT MAHMOOD-UR-REHMAN ANSARI MEREEN nizar NOREEN ZAHRA AMBREEN NAZ HAFIZ MUHAMMAD WALEED IQBAL ALI RAZA VLADAN PESIC IVICA DJALOVIC Department of Botany University of BalochistanQuetta08770Pakistan Department of Bioinformatics and Biotechnology Government College UniversityFaisalabad38000Pakistan Department of Botany University of AgricultureFaisalabad38040Pakistan Department of Food Science and Technology Muhammad Nawaz Shareef University of AgricultureMultan66000Pakistan Department of Agronomy Muhammad Nawaz ShareefUniversity of AgricultureMultan66000Pakistan College of Agriculture Fujian Agriculture and Forestry UniversityFuzhou350002China Department of Genetics and Plant Breeding Faculty of AgricultureUniversity of BelgradeBelgrade11000Serbia Institute of Field and Vegetable Crops National Institute of the Republic of SerbiaMaxim Gorki 30Novi Sad21000Serbia

Salinity is one of the major abiotic factors that limit the growth and productivity of *** application of plant growth regulators(PGRs)may help plants ameliorate the negative impacts of ***,a field experiment was conducted at the Botanical Garden University of Balochistan,Quetta,to explore the potential role of PGRs,i.e.,moringa leaf extract(MLE;10%),proline(PRO;1μM),salicylic acid(SA;250μM),and thiourea(TU;10 mM)in ameliorating the impacts of salinity(120 mM)on Plantago ovata,an important medicinal *** hampered plant photosynthetic pigments and metabolites but elevated oxidative ***,foliar application of PGRs enhanced photosynthetic pigments,including Chl b(21.11%),carotenoids(57.87%)except Chl a,activated the defense mechanisms by restoring and enhancing the metabolites,i.e.,soluble sugars(49.68%),soluble phenolics(33.34%),and proline(31.47%),significantly under salinity ***,foliar supplementation of PGRs under salt stress led to a decrease of about 43.02%and 43.27%in hydrogen peroxide and malondialdehyde content,***,PGRs can be recommended for improved photosynthetic efficiency and metabolite content that can help to get better yield under salt stress,with the best and most effective treatments being those of PRO and MLE to predominately ameliorate the harsh impacts of salinity.

关键词： Abiotic stress Proline Photosynthetic pigments Thiourea Salinity Salicylic acid

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Can Autoimmune Encephalitis Occur with Negative Markers? A Rare Case Report

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Case Reports in Clinical Medicine 2023年第2期12卷 31-36页

作者： Anas Mahmoud Ahmed Salem nizar Alyassin Moh’d Azzam Department of Internal Medicine St. Joseph’s University Medical Center Paterson USA

In our case, we present a case of a 27-year-old male who presented with progressively worsening altered mental status and seizures. Over the course of his admission to the hospital and intensive care unit, laboratory testing failed to find an offending agent to his presentation. Testing did result in the diagnosis of encephalitis, but an underlying cause was not found. After careful exclusion of bacterial, viral, and other types of encephalopathy, autoimmune encephalopathy was diagnosed despite the absence of commonly used markers of autoimmune encephalopathy. The presentation and symptoms of our patient led to a wide range of differentials, and a high index of suspicion was needed throughout his admission in order to obtain the appropriate tests. Although appropriate testing might be ordered, due to the sensitivities and specificities of all laboratory tests, these objective tests do produce false negative results at times. It is in these times that one must weigh the physical exam, clinical judgment, and the process of elimination to diagnose an underlying pathology. Autoimmune Encephalitis diagnosis can be broken down into possible, probable, and definitive diagnoses based on antibody testing results. In this case, we present a patient with probable autoimmune encephalitis that failed to yield positive autoimmune markers after extensive testing of other possible causes of encephalitis.

关键词： Autoimmune Encephalitis Seizures Paraneoplastic Syndrome Encephalitis Autoimmune

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Ohio solid organ transplantation consortium criteria for liver transplantation in patients with alcoholic liver disease

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World Journal of Hepatology 2016年第27期8卷 1149-1154页

作者： Kaveh Hajifathalian Annette Humberson Mohamad A Hanouneh David S Barnes Zubin Arora nizar N Zein Bijan Eghtesad Dympna Kelly Ibrahim A Hanouneh Department of Internal Medicine Cleveland Clinic Foundation Department of Transplant Social Work Cleveland Clinic Foundation Department of Gastroenterology and Hepatology Cleveland Clinic Foundation Department of General Surgery Cleveland Clinic Foundation

AIM To evaluate risk of recidivism on a case-by-case *** From our center's liver transplant program,we selected patients with alcoholic liver disease who were listed for transplant based on Ohio Solid Organ Transplantation Consortium(OSOTC) exception *** were considered to have either a low or medium risk of recidivism,and had at least one or three or more months of abstinence,*** were matched based on gender,age,and Model for End-Stage Liver Disease(MELD) score to controls with alcohol-induced cirrhosis from Organ Procurement and Transplant Network *** Thirty six patients with alcoholic liver disease were approved for listing based on OSOTC exception criteria and were matched to 72 *** patients(53%) with a median [Inter-quartile range(IQR)] MELD score of 24(13) received transplant and were followed for a median of 3.4 *** were matched to 38 controls with a median(IQR) MELD score of 25(9).At one and five years,cumulative survival rates(± standard error) were 90% ± 7% and 92% ± 5% and 73% ± 12% and 77% ± 8% in patients and controls,respectively(Log-rank test,P = 0.837).Four(21%) patients resumed drinking by last follow-up *** Compared to traditional criteria for assessment of risk of recidivism,a careful selection process with more flexibility to evaluate eligibility on a case-by-case basis can lead to similar survival rates after transplantation.

关键词： Alcohol-induced disorders Alcoholic liver cirrhosis Mortality Survival Liver transplantation

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应用于水溶液介质中喹啉氧化的电芬顿工艺实验设计方法(英文)

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电化学 2013年第5期19卷 460-471页

作者： TRABELSI SOUISSI Souhaila OTURAN Nihal BELLAKHAL nizar OTURAN Mehmet A Universitg Paris-Est Laboratoire Gegomatdriaux et Environnement (LGE)UPEMLV 77454 Marne-la-Vallee France Laboratoire de Chimie A naalytique et Electrochimie Departement de Chimie Facuhd des Sciences de Tunis Campus Universitaire 2092 El Manar Tunis Tunisio Dpartement de Genie Chimique et Biologique Institut National des Sciences Appliquees et de Technologie 1080 Tunis Tunisia

采用碳毡阴极和铂阳极的电芬顿工艺研究了喹啉模型分子—8-羟基喹啉硫酸盐(8-HQS)在水溶液介质中的降解行为.由于电化学诱导芬顿药剂(H2O2,Fe2+)产生大量的羟基活性基(●OH),成为与有机物发生反应直到有机物完全矿化的强有力氧化剂,因此... 详细信息

采用碳毡阴极和铂阳极的电芬顿工艺研究了喹啉模型分子—8-羟基喹啉硫酸盐(8-HQS)在水溶液介质中的降解行为.由于电化学诱导芬顿药剂(H2O2,Fe2+)产生大量的羟基活性基(●OH),成为与有机物发生反应直到有机物完全矿化的强有力氧化剂,因此,电芬顿工艺具有很强的氧化能力.采用正交实验设计确定了水溶液介质中8-HQS降解的操作参数.结果表明,电流密度和8-HQS的初始浓度是影响降解速度的主要因素.8-HQS浓度随着电解时间而减少,说明8-HQS的氧化遵循准一级反应动力学.通过竞争动力学方法确定的由●OH引起8-HQS氧化的绝对反应速度常数为1.62×109mol-1·L·s-1.通过Doehlert矩阵研究了8-HQS矿化的最佳实验参数,由此确定最佳条件下电芬顿工艺能导致8-HQS在水溶液中的准完全矿化(总有机成分去除率95%).对8-HQS水溶液的处理,使得8-HQS矿化前的最终产物为短链羧酸.同时研究了电芬顿处理中短链羧酸的演变行为.溶液毒性演变的跟踪研究发现,中间产物的毒性比8-HQS强,但溶液的毒性在中间产物矿化后可以完全消除.

关键词： 8-羟基喹啉硫酸盐电芬顿工艺羟基活性基降解 Doehlert矩阵矿化毒性

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Assessment of Knowledge and Attitude in a Sample of Patients with Rheumatoid Arthritis and Its Association with Disease Activity and Severity: A Cross-Sectional Study

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Open Journal of Rheumatology and Autoimmune Diseases 2014年第4期4卷 226-234页

作者： Sami Salman Ahmad SAlnuaimi nizar Abdul Lateef Rana Kadhum Rheumatology Unit Department of Medicine College of Medicine University of Baghdad Baghdad Iraq Community Medicine Department College of Medicine University of Baghdad Baghdad Iraq

Background: Rheumatoid arthritis (RA) is a chronic and disabling disease that has a major impact on the lives of patients. Objectives: To test the patients’ knowledge about their disease, its treatment, its complications, and if this affects severity of the disease as measured by the disease activity index (DAS 28). Patients and Methods: A sample of 100 patients with RA who met the Criteria of American College of Rheumatology for RA agreed to participate in this study over the period September 2011-March 2012. Patients’ data were obtained by personal interview. The questionnaire included demographic characteristics and the patients’ knowledge about their disease. The disease activity was measured using standard (DAS28). Results: Thirty three percent of the patients didn’t have an idea about their disease, 20% didn’t know the reason for the investigations, 49% didn’t know the treatment and 40% didn’t know the side effects of their medications. Most patients had a high disease activity index, and there was a poor correlation between patients’ educational level and the disease activity. Conclusions: Neither the educational level nor the frequency of hospital admissions had effects on the knowledge about this disease. As most patients had a high disease activity, a better knowledge may improve disease control and prevent complications.

关键词： Rheumatoid Arthritis Disease Burden Disease Awareness Patient’s Education Patient’s Knowledge Socio-Economic Factors Disease Activity Index

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Multifrequency excitation of a clamped–clamped microbeam:Analytical and experimental investigation

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Microsystems & Nanoengineering 2016年第1期2卷 278-283页

作者： nizar Jaber Abdallah Ramini Mohammad I.Younis Physical Science and Engineering Division King Abdullah University of Science and TechnologyThuwal 23955-6900Saudi Arabia Department of Mechanical Engineering State University of New York at BinghamtonBinghamtonNY 13902USA

Using partial electrodes and a multifrequency electrical source,we present a large-bandwidth,large-amplitude clamped–clamped microbeam resonator excited near the higher order modes of *** analytically and experimentally investigate the nonlinear dynamics of the microbeam under a two-source harmonic *** first-frequency source is swept around the first three modes of vibration,whereas the second source frequency remains *** additive and subtractive resonances are *** illustrated that by properly tuning the frequency and amplitude of the excitation force,the frequency bandwidth of the resonator is *** microbeam is fabricated using polyimide as a structural layer coated with nickel from the top and chromium and gold layers from the *** the Galerkin method,a reduced order model is derived to simulate the static and dynamic response of the device.A good agreement between the theoretical and experimental data are reported.

关键词： multifrequency nonlinear dynamics wideband resonator electrostatic combination resonances

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Energy Conservation in Reliable Wireless Sensor Networks

Energy Conservation in Reliable Wireless Sensor Networks

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2008 IEEE International Conference on Communications(ICC 2008)

作者： Fatma Bouabdallah nizar Bouabdallah Raouf Boutaba INRIA-IRISA Campus de Beaulieu 35042RennesFrance School of Computer Science University of Waterloo

Energy-efficiency is one of the major concerns in wireless sensor networks since it impacts the network *** this paper,we investigate the relationship between sensor network performance,particularly its lifetime,and the number of active reporting nodes N by using both analytical and simulation *** first demonstrate that decreasing the number of reporting nodes increases the number of reports that need to be sent to the sink,in order to achieve the desired information reliability regarding the detected *** the other hand,we show that reducing the number of reporting nodes alleviates the energy wastage due to *** on this tradeoff,and as a main contribution,we derive the optimal number of reporting nodes N opt energy that minimizes the energy consumed to report reliably the occurrence of an *** other words,we prove that limiting the reporting tasks of a detected event to a small subset of sensor nodes （i.e.,N opt energy）,instead of using all the sensor nodes in the event area,enables significant energy conservation.

关键词： Energy conservation Wireless sensor networks Peer to peer computing Event detection Energy consumption Energy efficiency Media Access Protocol Routing protocols Communications Society Computer network reliability

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Histological and magnetic resonance imaging assessment of Liqoseal in a spinal in vivo pig model

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Animal Models and Experimental Medicine 2023年第1期6卷 74-80页

作者： Emma M.H.Slot Wilhelmina Bergmann Ahmet Kinaci Bart de Boer nizar Moayeri Saskia Redegeld Sander van Thoor Tristan P.C.van Doormaal Department of Neurology and Neurosurgery University Medical Center UtrechtUtrechtthe Netherlands Department of Translational Neuroscience Brain CenterUniversity Medical Center UtrechtUtrechtthe Netherlands Department of Biomolecular Health Sciences Division of PathologyFaculty of Veterinary MedicineUtrecht UniversityUtrechtthe Netherlands Department of Neurosurgery Elizabeth TweeSteden ziekenhuisTilburgthe Netherlands Brain Technology Institute Utrechtthe Netherlands Department of Neurosurgery Clinical Neuroscience CenterUniversity Hospital ZurichZurichSwitzerland

Background:Liqoseal (Polyganics,B.V.) is a dural sealant patch for preventing postoperative cerebrospinal fluid (CSF) *** has been extensively tested preclinically and CE (Conformite Européenne) approved for human use after a first cranial in-human ***,the safety of Liqoseal for spinal application is still *** aim of this study was to assess the safety of spinal Liqoseal application compared with cranial application using histology and magnetic resonance imaging ***:Eight female Dutch Landrace pigs underwent laminectomy,durotomy with standard suturing and Liqoseal *** control animals underwent the same procedure without sealant *** histological characteristics and imaging characteristics of animals with similar survival times were compared to data from a previous cranial porcine ***:Similar foreign body reactions were observed in spinal and cranial *** foreign body reaction consisted of neutrophils and reactive fibroblasts in the first3 days,changing to a chronic granulomatous inflammatory reaction with an increasing number of macrophages and lymphocytes and the formation of a fibroblast layer on the dura by day *** Liqoseal plus dura thickness reached a maximum of 1.2mm(range 0.7-2.0mm) at day ***:The spinal dural histological reaction to Liqoseal during the first 7days was similar to the cranial dural *** did not swell significantly in both application areas over *** the current lack of a safe and effective dural sealant for spinal application,we propose that an in-human safety study of Liqoseal is the logical next step.

关键词： reaction resonance magnetic

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Delayed Dynamics of SIR Model for COVID-19

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Open Journal of Modelling and Simulation 2021年第2期9卷 146-158页

作者： Hameed K. Ebraheem nizar Alkhateeb Hussein Badran Ebraheem Sultan College of Technological Studies (PAAET) Kuwait City Kuwait

This paper presents a new modified SIR model which incorporates appropriate delay parameters leading to a more precise prediction of COVID-19 real time data. The efficacy of the newly developed SIR model is proven by comparing its predictions to real data obtained from four counties namely Germany, Italy, Kuwait, and Oman. Two included delay periods for incubation and recovery within the SIR model produce a sensible and more accurate representation of the real time data. In the absence of the two-delay period () the dynamical behavior of the model will not correspond to today’s picture and lag the detection of the epidemic peak. The reproductive number R0 is defined for the model for values of recovery time delay of the infective case. The effect of recovery time

COVID-19 SIR Compartmental Model Forecasting

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