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Utilization of Nanomaterials as Anode Modifiers for Improving Microbial Fuel Cells Performance

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Journal of Renewable Materials 2020年第12期8卷 1581-1605页

作者： nishit Savla Raksha Anand Soumya Pandit Ram Prasad Amity Institute of Biotechnology Amity UniversityMumbaiIndia Department of Life Sciences School of Basic Sciences and ResearchSharda UniversityGreater Noida201306India Department of Botany Mahatma Gandhi Central UniversityBihar845401India

Microbial fuel cells(MFCs)are an attractive innovation at the nexus of energy and water security for the *** utilizes electrochemically active microorganisms to oxidize biodegradable substrates and generate bioelectricity in a single *** material of the anode plays a vital role in increasing the MFC’s power *** anode in MFC can be upgraded using nanomaterials providing benefits of exceptional physicochemical *** nanomaterials in anode gives a high surface area,improved electron transfer promotes electroactive *** power output in terms of Direct current(DC)can be obtained as the consequence of improved microbe-electrode ***,several limitations like complex synthesis and degeneration of property do exist in the development of nanomaterial-based *** present review discusses different renewable nanomaterial applied in the anode to recover bioelectricity in *** nanomaterials have emerged in the past decade as promising materials for anode con*** materials have also demonstrated the capacity to become potential anode materials of *** of a few transition metal oxides have been explored for efficient extracellular electron transport(EET)from microbes to the anode.

关键词： Microbial fuel cell(MFC) anodic modifications capacitance carbon nanotubes graphene porous carbons metallic nanomaterials power density coulombic efficiency

Blepharis persica increases testosterone biosynthesis by modulating StAR and 3β-HSD expression in rat testicular tissues

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Asian pacific Journal of Reproduction 2022年第1期11卷 27-34,I0001-I0003页

作者： Nilesh Gaikar nishit Patel Samir Patel Priyal Patel Piyush Chudasama Manan Raval Department of Pharmacognosy Ramanbhai Patel College of PharmacyCharotar University of Science and TechnologyCHARUSAT CampusChangaGujaratIndia Department of Pharmaceutical Chemistry Ramanbhai Patel College of PharmacyCharotar University of Science and TechnologyCHARUSAT CampusChangaGujaratIndia Department of Pharmacology Ramanbhai Patel College of PharmacyCharotar University of Science and TechnologyCHARUSAT CampusChangaGujaratIndia Research Scientist R&D UnitSat-Kaival Hospital Pvt.LtdAnand388001 GujaratIndia

Objective:To evaluate the effect of methanolic extract and ethyl acetate fraction of methanol extract prepared from the seeds of Blepharis(B.)persica on testosterone biosynthesis and also to elucidate the underlying ***:Forty-eight male Wistar rats were divided into eight groups(n=6 per group).GroupⅠreceived 0.3%w/w gum acacia suspension *** served as the normal control ***Ⅱwas administered testosterone propionate in arachis oil *** the positive control ***ⅢtoⅣreceived *** methanolic extract *** doses of 50,100 and 200 mg/kg body ***ⅥtoⅦreceived *** ethyl acetate fraction *** doses of 50,100 and 200 mg/kg body *** testis was used for biochemical estimation and histological *** effects of methanolic extract and ethyl acetate fraction of *** on testicular testosterone,mRNA expression corresponding to steroidogenic acute regulatory protein(StAR)and 3β-hydroxysteroid dehydrogenase(3β-HSD)along with 3β-HSD enzyme assay were evaluated in testicular tissues and sperm *** acetate fraction of *** was subjected to column *** studies were performed using TM3 cell line at three dose levels(50,100,200μg/mL),each for methanolic extract,ethyl acetate fraction and 2-benzoxazolinone for evaluation of their comparative effect on testosterone ***:Ethyl acetate fraction and methanolic extract of *** could elevate the testicular testosterone content compared to the normal control *** treatment with methanolic extract and ethyl acetate fraction of *** increased the expression of mRNA corresponding to StAR by 6.7 fold and 10.6 fold,respectively,whereas the mRNA expression of 3β-HSD increased by 5.7 fold and 7.3 fold,***,fraction and extract treatment exhibited increased 3β-HSD activity in the testicular tissues and were found to elevate sperm concentration in seminal *** spermatogenic potential was further en

关键词： Blepharis persica Testosterone Spermatogenic Leydig cells 3β-hydroxysteroid dehydrogenase Steroidogenic acute regulatory protein mRNA expression TM3 cell line

A Comprehensive Review on Oxygen Reduction Reaction in Microbial Fuel Cells

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Journal of Renewable Materials 2022年第3期10卷 665-697页

作者： Pooja Dange nishit Savla Soumya Pandit Rambabu Bobba Sokhee P.Jung Piyush Kumar Gupta Mohit Sahni Ram Prasad Amity Institute of Biotechnology Amity UniversityMumbai410206India Department of Life Sciences School of Basic Sciences and ResearchSharda UniversityGreater Noida201306India Department of Physics Southern University and A&M CollegeBaton Rouge70813USA Department of Environment and Energy Engineering Chonnam National UniversityGwangju61186Korea Department of Physics School of Basic Sciences and ResearchSharda UniversityGreater Noida201306India Department of Botany Mahatma Gandhi Central UniversityBihar845401India

The focus of microbial fuel cell research in recent years has been on the development of materials,microbes,and transfer of charges in the system,resulting in a substantial improvement in current density and improved power *** cathode is generally recognized as the limiting factor due to its high-distance proton transfer,slow oxygen reduction reaction(ORR),and expensive *** heterogeneous reaction determines power gen-eration in *** comprehensive review describes-recent advancements in the development of cathode mate-rials and catalysts associated with *** recent studies indicated the utilization of different metal oxides,the ferrite-based catalyst to overcome this *** studies conclude that some cathode materials,in parti-cular,graphene-based conductive polymer composites with non-precious metal catalysts provide substantial ben-efits for sustainable development in the field of ***,it also highlights the potentiality to replace the conventional platinum air cathode for the large-scale production of the next generation of *** was evi-dent from the experiments that cathode catalyst needs to be blended with conductive carbon materials to make cathode conductive and efficient for *** review discusses various antifouling strategies for cathode biofoul-ing and its effect on the MFC ***,it also depicts cost estimations of various catalysts essential for further scale-up of MFC technology.

关键词： Cathode catalyst microbial fuel cell(MFC) nanomaterials oxygen reduction reaction(ORR) biofouling biocathode

Omentum facilitates liver regeneration

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World Journal of Gastroenterology 2009年第9期15卷 1057-1064页

作者： Ashok K Singh nishit Pancholi Jilpa Patel Natalia O Litbarg Krishnamurthy P Gudehithlu Perianna Sethupathi Mark Kraus George Dunea Jose AL Arruda Department of Medicine Stroger Hospital of Cook CountyChicago IL 60612United States Hektoen Institute of Medicine Chicago IL 60612United States Loyola-Hines Medical Center Maywood IL 60612United States University of Illinois at Chicago and the Chicago VAMC Chicago IL 60612United States

AIM:To investigate the mechanism of liver regeneration induced by fusing the omentum to a small traumatic injury created in the liver. We studied three groups of rats. In one group the rats were omentectomized; in another group the omentum was left in situ and was not activated,and in the third group the omentum was activated by polydextran particles. METHODS:We pre-activated the omentum by injecting polydextran particles and then made a small wedge wound in the rat liver to allow the omentum to fuse to the wound. We monitored the regeneration of the liver by determining the ratio of liver weight/body weight,by histological evaluation (including immune staining for cytokeratin-19,an oval cell marker),and by testing for developmental gene activation using reverse transcription polymerase chain reaction (RT-PCR). RESULTS:There was no liver regeneration in the omentectomized rats,nor was there significant regeneration when the omentum was not activated,even though in this instance the omentum had fusedwith the liver. In contrast,the liver in the rats with the activated omentum expanded to a size 50% greater than the original,and there was histologically an interlying tissue between the wounded liver and the activated omentum in which bile ducts,containing cytokeratin-19 positive oval cells,extended from the wound edge. In this interlying tissue,oval cells were abundant and appeared to proliferate to form new liver tissue. In rats pre-treated with drugs that inhibited hepatocyte growth,liver proliferation was ongoing,indicating that regeneration of the liver was the result of oval cell expansion. CONCLUSION:Activated omentum facilitates liver regeneration following injury by a mechanism that depends largely on oval cell proliferation.

关键词： Cytokeratin Foreign body Growth factors Oval cell Progenitor cells

Protective effects of long term antiplatelet and anticoagulant therapy in hospitalized patients with inflammatory bowel disease

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2024年第6期15卷 28-38页

作者： Madhav Changela Sagar Pandey Janak Bahirwani nishit Patel Maulik Kaneriya Sanket D Basida Anish shah Rahul Thakur Krishna Bodrya Suruchi Jai Kumar Ahuja Yecheskel Schneider Department of Internal Medicine One Brooklyn Health System/Interfaith Medical CenterBrooklynNY 11213United States Department of Gastroenterology St.Luke's University Health NetworkBethlehemPA 18015United States Department of Internal Medicine University of MissouriColumbiaMO 65212United States Department of Internal Medicine Bronxcare Health SystemBronxNY 10457United States Department of Internal Medicine Albert Einstein College of Medicine/Jacobi Medical CenterBronxNY 10461United States Department of Internal Medicine Lehigh Valley Health NetworkEastonPA 18045United States Department of Data Sciences Sarepta TherapeuticsCambridgeMA 02124United States

BACKGROUND Inflammatory bowel disease(IBD),with its rising prevalence rates is associated with an increased risk of cardiovascular and thromboembolic *** and/or anticoagulants agents are often prescribed but the literature on the impact of long-term anticoagulation and/or antiplatelet use among patients hospitalized with IBD is *** aim of this study is to assess the outcomes of patients hospitalized with IBD on antiplatelet and/or anticoagulant *** To investigate the effects of long-term use of antiplatelets/anticoagulants on clinical outcomes in patients hospitalized with *** We conducted a retrospective cohort study using the Nationwide Inpatient Sample database,including all adult IBD patients hospitalized in the United States from 2016 to *** cohorts were stratified based on antiplatelet/anticoagulant therapy *** regression analysis was done to assess outcomes,adjusting for potential *** primary outcome was mortality,whereas length of stay(LOS),total parenteral nutrition,acute kidney injury,sepsis,shock,gastrointestinal bleeding,need for colonoscopy/sigmoidoscopy,abdominal surgery and total hospitalization charges were secondary *** Among 374744 hospitalized IBD patients,antiplatelet or anticoagulant therapy alone was associated with significantly lower in-hospital mortality and reduced healthcare utilization,including shorter LOS and decreased hospitalization *** therapy was associated with a protective effect on mortality,but did not reach statistical ***,therapy did not exacerbate disease severity or complications,although higher odds of gastrointestinal bleeding were *** Our study highlights the potential benefits of long-term anticoagulation/antiplatelet therapy in hospitalized IBD patients,with improved mortality outcomes and healthcare *** concerns regarding gastrointestinal bleeding exist,the overall safety pr

关键词： Inflammatory bowel disease Anticoagulation Antiplatelet therapy Healthcare utilization Mortality