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Aconitum heterophyllum *** Royle:A critically endangered medicinal herb with rich potential for use in medicine

Journal of Integrative Medicine 2022年第2期20卷 104-113页

作者： Tareq A.Wani Zahoor A.Kaloo nisar a.dangroo Plant Tissue Culture Laboratory Department of BotanyUniversity of KashmirSrinagarJammu and Kashmir 190006India Department of Chemistry National Institute of TechnologySrinagarJammu and Kashmir 190006India

Aconitum heterophyllum(Patrees)is a critically endangered medicinal herb of the northwestern Himalayas and has enormous pharmacological *** is the only nonpoisonous member of the genus Aconitum,and has been used as a medicinal herb since ancient *** is an important ingredient in many traditional systems of ***,it is harvested for its roots,and its medicinal properties are due to the presence of diverse bioactive secondary metabolites,commonly known as *** understanding of the pharmacological properties of this intriguing genus is continuously growing due to its broad chemical *** therapeutic uses identified by traditional medicinal practice are receiving extensive *** in vitro experimental investigations of *** have reported the analgesic,anti-inflammatory,antiarrhythmic,antiparasitic and anticancer properties,as well as its effects on the central nervous *** this review,we highlight the classification,distribution,commerce,traditional uses,phytochemistry,pharmacology and conservation measures relevant to this ***,this review includes the biosynthetic pathways of ***’s key constituents,which could be targeted to enhance the expression levels of desired metabolites via genetic *** the genomics,transcriptomics,proteomics and metabolomic aspects of this species would be helpful in developing highly designed genotypes and chemotypes of this species to be used in commercial production.

关键词： Aconitum heterophyllum Ethnopharmocology Herbal medicine Phytochemistry

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