检索结果-南通市图书馆

Associating liver partition and portal vein ligation for staged hepatectomy versus sequential transarterial chemoembolization and portal vein embolization in staged hepatectomy for HBV-related hepatocellular carcinoma:a randomized comparative study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary Surgery and Nutrition 2022年第1期11卷 38-51,I0006页

作者： Peng-Peng Li Gang Huang ning-yang jia Ze-Ya Pan Hui Liu Yun yang Cheng-jian He Wan Yee Lau Ye-Fa yang Wei-Ping Zhou Eastern Hepatobiliary Surgery Hospital ShanghaiChina Faculty of Medicine The Chinese University of Hong KongPrince of Wales HospitalHong KongChina

Background:Both portal vein embolization(PVE)and associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)have merits and demerits when used in patients with unresectable liver cancers due to insufficient volumes in future liver remnant(FLR).Methods:This study was a single-center,prospective randomized comparative *** with the diagnosis of hepatitis B related hepatocellular carcinoma(HCC)were randomly assigned in a 1:1 ratio to the 2 *** primary endpoints were tumor resection and three-year overall survival(OS)***:Between November 2014 to June 2016,76 patients with unresectable HBV-related HCC due to inadequate volume of FLR were randomly assigned to ALPPS groups(n=38)and TACE+PVE groups(n=38).Thirty-seven patients(97.4%)in the ALPPS group compared with 25 patients(65.8%)in the TACE+PVE group were able to undergo staged hepatectomy(risk ratio 1.48,95%CI:1.17-1.87,P<0.001).The three-year OS rate of the ALPPS group(65.8%)(95%CI:50.7-80.9)was significantly better than the TACE+PVE group(42.1%)(95%CI:26.4-57.8)(HR 0.50,95%CI:0.26-0.98,two-sided P=0.036).However,no significant difference in the OS rates between patients who underwent tumor resection in the 2 groups of patients was found(HR 0.80,95%CI:0.35-1.83,two-sided P=0.595).Major postoperative complications rates after the stage-2 hepatectomy were 54.1%in the ALPPS group and 20.0%in the TACE+PVE group(risk ratio 2.70,95%CI:1.17-6.25,P=0.007).Conclusions:ALPPS resulted in significantly better intermediate-term OS outcomes,at the expenses of a significantly higher perioperative morbidity rate compared with TACE+PVE in patients who had initially unresectable HBV-related HCC.

关键词： Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS) portal vein embolization(PVE) hepatocellular carcinoma(HCC) resection rate prognosis

Cross-modality PET/CT and contrast-enhanced CT imaging for pancreatic cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第10期21卷 2988-2996页

作者： jian Zhang Chang-Jing Zuo ning-yang jia jian-Hua Wang Sheng-Ping Hu Zhong-Fei Yu Yuan Zheng An-Yu Zhang Xiao-Yuan Feng Department of Nuclear Medicine Changhai Hospital Second Military Medical University Department of Radiology Eastern Hepatobiliary Surgery HospitalSecond Military Medical University Department of Radiology the Affiliated Hospital of Medical School of Ningbo University Department of PET/CT Center No.411 Hospital of PLA Department of Radiology No.85 Hospital of PLA Department of Radiology Huashan HospitalFudan University

AIM:To explore the diagnostic value of the crossmodality fusion images provided by positron emission tomography/computed tomography(PET/CT) and contrast-enhanced CT(CECT) for pancreatic cancer(PC).METHODS:Data from 70 patients with pancreatic lesions who underwent CECT and PET/CT examinations at our hospital from August 2010 to October 2012were ***/CECT for the cross-modality image fusion was obtained using Ture D *** diagnostic efficiencies of PET/CT,CECT and PET/CECT were calculated and compared with each other using aχ2 test.P0.05for each).In 17 of the 50 patients with PC confirmed by histology or clinical follow-up,distant metastasis was *** differences in the sensitivity and NPV between CECT and PET/CECT in detecting distant metastasis were statistically significant(P<0.05 for each).CONCLUSION:Cross-modality image fusion of PET/CT and CECT is a convenient and effective method that can be used to diagnose and stage PC,compensating for the defects of PET/CT and CECT when they are conducted individually.

关键词： Pancreatic neoplasms Positron-emission tomography

Nomogram prediction of vessels encapsulating tumor clusters in small hepatocellular carcinoma≤3 cm based on enhanced magnetic resonance imaging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第5期16卷 1808-1820页

作者： Hui-Lin Chen Rui-Lin He Meng-Ting Gu Xing-Yu Zhao Kai-Rong Song Wen-Jie Zou ning-yang jia Wan-Min Liu School of Health Science and Engineering University of Shanghai for Science and TechnologyShanghai 200093China Department of Radiology The Third Affiliated Hospital of Shanghai Naval Military Medical UniversityShanghai 200438China Department of Radiology Tongji University Affiliated Tongji HospitalShanghai 200065China

BACKGROUND Vessels encapsulating tumor clusters(VETC)represent a recently discovered vascular pattern associated with novel metastasis mechanisms in hepatocellular carcinoma(HCC).However,it seems that no one have focused on predicting VETC status in small HCC(sHCC).This study aimed to develop a new nomogram for predicting VETC positivity using preoperative clinical data and image features in sHCC(≤3 cm)*** To construct a nomogram that combines preoperative clinical parameters and image features to predict patterns of VETC and evaluate the prognosis of sHCC *** A total of 309 patients with sHCC,who underwent segmental resection and had their VETC status confirmed,were included in the *** patients were recruited from three different hospitals:Hospital 1 contributed 177 patients for the training set,Hospital 2 provided 78 patients for the test set,and Hospital 3 provided 54 patients for the validation *** predictors of VETC were identified through univariate and multivariate logistic *** independent predictors were then used to construct a VETC prediction model for *** model’s performance was evaluated using the area under the curve(AUC),calibration curve,and clinical decision ***,Kaplan-Meier survival analysis was performed to confirm whether the predicted VETC status by the model is associated with early recurrence,just as it is with the actual VETC status and early *** Alpha-fetoprotein_lg10,carbohydrate antigen 199,irregular shape,non-smooth margin,and arterial peritumoral enhancement were identified as independent predictors of *** model incorporating these predictors demonstrated strong predictive *** AUC was 0.811 for the training set,0.800 for the test set,and 0.791 for the validation *** calibration curve indicated that the predicted probability was consistent with the actual VETC status in all three ***,the decision curve analysis demonstr

关键词： Small hepatocellular carcinoma Vessels encapsulating tumor clusters Nomogram Magnetic resonance imaging Multicenter

Amino acid derivatives of pyropheophorbide-a ethers as photosensitizer： Synthesis and photodynamic activity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2016年第5期27卷 623-626页

作者： Zhi Meng Bin Shan Ling Zhang Gui-Yan Han Ming-Hui Liu ning-yang jia Zhen-Yuan Miao Wan-Nian Zhang Chun-Quan Sheng jian-Zhong Yao Department of Medicinal Chemistry School of Pharmacy Second Military Medical University Shanghai 200433 China Department of Pharmacy Fujian University of Traditional Chinese Medicine Fuzhou 350122 China Department of Radiology Shanghai Eastern Hepatobiliary Surgery Hospital Second Military Medical University Shanghai 200438 China

Ten new water-soluble amino acid conjugates of pyropheophorbide-a ethers 4a-4J were synthesized and investigated for their in vitro photodynamic antitumor activity. The results showed that all compounds exhibited higher phototoxicity and lower dark toxicity against three kinds of tumor cell lines than BPD-MA. In particular, the most phototoxic compound 4d and 4j individually showed ICso values of 41 nmol/L and 33 nmol/L against HCT116 cell, which represented 7.8- and 9.7-fold increase of antitumor potency compared to BPD-MA, respectively, suggesting that they were promising photosensitizers for PDT applications because of their strong absorption at long wavelength （λmax 〉 650 nm）, high phototoxicitv, low dark cvtotoxicitv and ~ood water-solubility.

关键词： Photodynamic therapy (PDT) Photosensitiser Pyropheophorbide-α Chlorin Antitumor

维普期刊数据库

Anomalous quality factor evolution of induced transparency in a virtualized coupled-oscillator system

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 148-155页

作者： Yunhan yang Han jia Tuo Liu Yuzhen yang Jun yang Key Laboratory of Noise and Vibration Research Institute of Acoustics Chinese Academy of Sciences University of Chinese Academy of Sciences State Key Laboratory of Acoustics Institute of Acoustics Chinese Academy of Sciences

The phenomenon of induced transparency, characterized by a high quality(Q) factor, holds significant importance in the fields of high-precision sensing, energy storage and wave manipulation. Conventional transparency systems are often constrained by the limited experimentally accessible parameter space and the lack of independent control over intrinsic parameters, thereby hindering advanced research on high-Q effects. Here we propose a virtualized coupled-oscillator system that enables reconfigurable induced transparency in the reflection spectrum. By virtually incorporating a pair of coupled oscillators into an individual acoustic meta-atom, we achieve the manipulation of induced transparency in a decoupled, wide-ranging, and elaborate manner. Exploiting the diverse evolutions across the intrinsic parameter space, we show experimentally a counter-intuitive increase in the Q-factor of the transparency window, which is attributed to the enhanced dissipation of the bright ***, a constant group delay at the center frequency is observed accompanying this evolution. Our work demonstrates an intriguing platform as well as a novel strategy to engineer high-Q induced transparency phenomenon, and paves the way towards applications in programmable acoustic sensors, filters and slow-wave devices.

关键词： induced transparency acoustic meta-atom high quality-factor scattering programmable intrinsic parameter

Synergistic promotion strategy of “dual-site” and “dual-path” to enhance the C–C coupling between CO2 and HCHO driven by photoelectrocatalysis

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 39-49页

作者： Hongqiang yang jianfeng Zheng Guoyu Wang Yifei Gao Yatao yang jia Li Xiaojin Han Yan Cui Zhanggen Huang National Key Laboratory of High Efficiency and Low Carbon Utilization of Coal Institute of Coal Chemistry Chinese Academy of Science University of Chinese Academy of Science Shenyang University of Chemical Technology

Photoelectrocatalytic coupling CO2and volatile organic compounds （VOCs） is a promising green strategy for the synergistic conversion of the two carbon-containing resources to *** catalytic efficiency is always at the mercy of chemical inertness of CO2and the competitive hydrogen evolution of ***,a modified g-C3N4/ZnAl-LDH Z-scheme heterojunction catalyst with dual reaction site was rationally designed and precisely *** Faraday efficiency of ethanol reached 68.67%with a corresponding formation rate of 227.3μmol *** revealed by in-situ characterizations and density functional theory calculations,CO2and HCHO were absorbed at Zn site and N site,***,*CO generated from CO2and HCHO was converted to*CH3O and*CHO on the dual-active-site *** detailed reaction mechanism experiments indicated that C–C coupling only occurred between*CO and*CH3O in electrocatalysis *** from the“*CO+*CH3O”path,another“*CO+*CHO”coupling path was also detected in photoelectrocatalytic *** selectivity of ethanol was significantly enhanced due to the synthesis of dual-site catalyst and the dual-path coupling path between CO2and HCHO simultaneously driven by light and electricity.

关键词： Photoelectrocatalysis Z-scheme C–C coupling Ethanol

Sine oculis homeobox homolog family function in gastrointestinal cancer:Progression and comprehensive analysis

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2025年第1期16卷 10-24页

作者： yang-Zheng Lan Zheng Wu Wen-jia Chen Xin-ning Yu Hua-Tao Wu Jing Liu Department of The Breast Center Cancer Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of General Surgery First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

The sine oculis homeobox homolog(SIX)family,a group of transcription factors characterized by a conserved DNA-binding homology domain,plays a critical role in orchestrating embryonic development and organogenesis across various organisms,including *** six distinct members,from SIX1 to SIX6,each member contributes uniquely to the development and differentiation of diverse tissues and organs,underscoring the versatility of the SIX *** or mutations in SIX genes have been implicated in a spectrum of developmental disorders,as well as in tumor initiation and progression,highlighting their pivotal role in maintaining normal developmental trajectories and cellular *** to target the transcriptional complex of the SIX gene family have emerged as a promising strategy to inhibit tumor *** the development of inhibitors targeting this gene family is still in its early stages,the significant potential of such interventions holds promise for future therapeutic ***,this review aimed to comprehensively explore the advancements in understanding the SIX family within gastrointestinal cancers,focusing on its critical role in normal organ development and its implications in gastrointestinal cancers,including gastric,pancreatic,colorectal cancer,and hepatocellular *** conclusion,this review deepened the understanding of the functional roles of the SIX family and explored the potential of utilizing this gene family for the diagnosis,prognosis,and treatment of gastrointestinal cancers.

关键词： Sine oculis homeobox homolog Gastrointestinal cancer Transcription factor Development Regulation Diagnosis Therapeutics

我国新型农业经营主体政策分析——基于国家层面政策文本

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

安徽农业科学 2024年第13期52卷 189-195页

作者：杨柠嘉王见西南林业大学经济管理学院云南昆明650224

随着我国进入高质量发展阶段,新型农业经营主体已然成为农业现代化的核心推动力量,加快构建新型农业经营主体政策体系对于新型农业经营主体的发展具有重要意义。基于此,从政策工具、政策内容和政策结构3个维度对我国2012—2022年的新型... 详细信息

随着我国进入高质量发展阶段,新型农业经营主体已然成为农业现代化的核心推动力量,加快构建新型农业经营主体政策体系对于新型农业经营主体的发展具有重要意义。基于此,从政策工具、政策内容和政策结构3个维度对我国2012—2022年的新型农业经营主体政策进行文本量化研究,探讨政策的发展变化。结果表明,政策工具以环境型工具为主导地位、供给型与需求型政策工具相对使用不足,且政策子工具使用不均衡;资本是内容涉及最多的因素,土地要素涉及最少,发展要素内分布也存在较大差异。提出应优化政策工具、扩展资金支持渠道、完善制度机制建设,提高土地流转交易、重视人才建设,建立人才招募机制、完善政策落实与绩效评估机制。

关键词：新型农业经营主体政策政策工具文本量化

维普期刊数据库博看期刊

Ideal Bi-Based Hybrid Anode Material for Ultrafast Charging of Sodium-Ion Batteries at Extremely Low Temperatures

在线全文

学校读者我要写书评

暂无评论

NANO-MICRO LETTERS 2025年第1期17卷 1-16页

作者： Bai, Jie jia, jian Hui Wang, Yu yang, Chun Cheng jiang, Qing Jilin Univ Key Lab Automobile Mat Sch Mat Sci & Engn Minist Educ Changchun 130022 Peoples R China

Metallic nanoparticles with excellent size controllability and high loading rate are obtained via ultrafast high temperature shock *** Bi/CNRs-15 electrode exhibits an unprecedented rate performance (237.9 mAh g-1 at 2 A g-1) at - 60 degrees C, while the energy density of the full cell can reach to 181.9 Wh kg-1 at - 40 degrees C.A novel strategy of high-rate activation is proposed to obtain high capacity and superior stability at low temperature by creating new active sites for interfacial reaction. Sodium-ion batteries have emerged as competitive substitutes for low-temperature applications due to severe capacity loss and safety concerns of lithium-ion batteries at - 20 degrees C or lower. However, the key capability of ultrafast charging at ultralow temperature for SIBs is rarely reported. Herein, a hybrid of Bi nanoparticles embedded in carbon nanorods is demonstrated as an ideal material to address this issue, which is synthesized via a high temperature shock method. Such a hybrid shows an unprecedented rate performance (237.9 mAh g-1 at 2 A g-1) at - 60 degrees C, outperforming all reported SIB anode materials. Coupled with a Na3V2(PO4)3 cathode, the energy density of the full cell can reach to 181.9 Wh kg-1 at - 40 degrees C. Based on this work, a novel strategy of high-rate activation is proposed to enhance performances of Bi-based materials in cryogenic conditions by creating new active sites for interfacial reaction under large current.

关键词： Bi nanoparticles High temperature shock High-rate activation Ultrafast charging Low-temperature sodium-ion batteries