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Aflatoxin B1 decreased flesh flavor and inhibited muscle development in grass carp(Ctenopharyngodon idella)

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Animal Nutrition 2024年第3期18卷 27-38页

作者： Xiang ning He zhen zhen Zeng Wei Dan jiang Pei Wu Yang Liu Sheng Yao Kuang Ling Tang Shu Wei Li Lin Feng Xiao Qiu Zhou Animal Nutrition Institute Sichuan Agricultural UniversityChengdu 611130China Fish Nutrition and Safety Production University Key Laboratory of Sichuan Province Sichuan Agricultural UniversityChengdu 611130China Key Laboratory for Animal Disease-Resistance Nutrition Ministry of EducationMinistry of Agriculture and Rural AffairsKey Laboratory of Sichuan ProvinceChengdu 611130China Animal Nutrition Institute Sichuan Academy of Animal ScienceChengdu 610066China

In nature,aflatoxins,especially aflatoxin B1(AFB1),are the common mycotoxins,which cause serious health problems for humans and *** paper aimed to study the effects of AFB1 on flesh flavor and muscle development of grass carp(Ctenopharyngodon idella)and its *** were 1440 individual fish in total,with 6 treatments and each treatment replicated 3 *** 6 treatments were fed a control diet with different doses of AFB1(0.04,29.48,58.66,85.94,110.43 and 146.92μg/kg diet)for 60 ***1 increased myofiber diameter,as well as decreased myofiber density of grass carp muscle(P<0.05).The contents of free amino acid decreased gradually(P<0.05)as dietary AFB1 increased in the muscle of grass *** levels of reactive oxygen species,malonaldehyde and protein carbonyl(PC)were increased(P<0.05)with the dietary AFB1 *** levels of antioxidant enzyme(glutathione peroxidase,glutathione,glutathione reductase,total antioxidant capacity,anti-superoxide anion,and anti-hydroxyl radical)were decreased(P<0.05)with the dietary AFB1 *** addition,dietary AFB1 decreased the content of collagen,and downregulated the mRNA and protein levels of transforming growth factor-β(TGF-β)/Smads signaling pathway in grass carp muscle(P<0.05).The mRNA and protein levels of myogenic regulatory factors were downregulated in grass carp muscle(P<0.05).Furthermore,the activities of matrix metalloproteinase-2(MMP-2)and matrix metalloproteinase-9(MMP-9)were increased(P<0.05),and the protein levels of phosphorylate-38 mitogen-activated protein kinase(p-p38MAPK),phosphorylate-c-Jun N-terminal kinase,urokinase-type plasminogen activator(uPA),MMP-2 and MMP-9 were upregulated(P<0.05),but collagenⅠ,lamininβ1 and fibronectin were downregulated(P<0.05)with the dietary AFB1 increased in the muscle of grass *** on the results of this study,we can draw the following conclusion:dietary AFB1 might damage flesh flavor and inhibit the muscle development through MAPK/uPA/MMP/extrac

关键词： Aflatoxin B1 Flesh flavor Muscle development Grass carp

Distributed intrusion detection for mobile ad hoc networks

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Journal of Systems Engineering and Electronics 2008年第4期19卷 851-859页

作者： Yi Ping jiang Xinghao Wu Yue Liu ning School of Information Security Engineering Shanghai Jiaotong Univ Shanghai 200030 P. R. China State Key Lab of Information Security Graduate School of Chinese Academy of Sciences Beijing 100039 P. R. China

Mobile ad hoc networking （MANET） has become an exciting and important technology in recent years, because of the rapid proliferation of wireless devices. Mobile ad hoc networks is highly vulnerable to attacks due to the open medium, dynamically changing network topology, cooperative algorithms, and lack of centralized monitoring and management point. The traditional way of protecting networks with firewalls and encryption software is no longer sufficient and effective for those features. A distributed intrusion detection approach based on timed automata is given. A cluster-based detection scheme is presented, where periodically a node is elected as the monitor node for a cluster. These monitor nodes can not only make local intrusion detection decisions, but also cooperatively take part in global intrusion detection. And then the timed automata is constructed by the way of manually abstracting the correct behaviours of the node according to the routing protocol of dynamic source routing （DSR）. The monitor nodes can verify the behaviour of every nodes by timed automata, and validly detect real-time attacks without signatures of intrusion or trained data. Compared with the architecture where each node is its own IDS agent, the approach is much more efficient while maintaining the same level of effectiveness. Finally, the intrusion detection method is evaluated through simulation experiments.

关键词： mobile ad hoc networks routing protocol security intrusion detection timed automata.

CFD simulation of internal-loop airlift reactor using EMMS drag model

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Particuology 2015年第2期13卷 124-132页

作者： Tingting Xu Xuedong jiang ning Yang Jiahua Zhu State Key Laboratory of Multi-Phase Complex Systems Institute of Process EngineeringChinese Academy of Sciences University of Chinese Academy of Sciences Department of Chemical Engineering Xi'an Jiaotong University School of Chemical Engineering Sichuan University

The simulation of internal-loop airlift reactors is challenging because complex meso-scale structures exist in different sections of the reactor, separated by the draft tube. This paper reports on the computational fluid dynamics （CFD） simulation of internal-loop airlift reactors using a new drag model derived from the dual-bubble-size （DBS） model, an extended energy-minimization multi-scale （EMMS） approach for gas-liquid flows. Compared with the traditional Schiller-Naumann （S-N） correlation, the new model improves the simulation of gas holdup in the riser and downcomer significantly. In particular, gas holdup and circulation of two-phase flow can be modeled successfully using the new model, whereas traditional drag models such as the S-N correlation show an absence of gas in the downcomer. The simulation demonstrates the advantage and potential of this new model for internal-loop airlift reactors.

关键词： Computational fluid dynamics Internal-loop Airlift Multi-scale Multiphase flow Hydrodynamics

Strategies for preventing peritoneal fibrosis in peritoneal dialysis patients： new insights based on peritoneal inflammation and angiogenesis

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Frontiers of Medicine 2017年第3期11卷 349-358页

作者： zhen Zhang Na jiang Zhaohui Ni Department of Nephrology Ren Ji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200127 China

Peritoneal dialysis （PD） is an established form of renal replacement therapy. Long-term PD leads to morphologic and functional changes to the peritoneal membrane （PM）, which is defined as peritoneal fibrosis, a known cause of loss of peritoneal ultrafiltration capacity. Inflammation and angiogenesis are key events during the pathogenesis of peritoneal fibrosis. This review discusses the pathophysiology of peritoneal fibrosis and recent research progress on key fibrogenic molecular mechanisms in peritoneal inflammation and angiogenesis, including Toll-like receptor ligand-mediated, NOD-like receptor protein 3/interleukin-lp, vascular endothelial growth factor, and angiopoietin-2/Tie2 signaling pathways. Furthermore, novel strategies targeting peritoneal inflammation and angiogenesis to preserve the PM are discussed in depth.

关键词： peritoneal dialysis peritoneal fibrosis inflammation angiogenesis

Rotation errors in numerical manifold method and a correction based on large deformation theory

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Frontiers of Structural and Civil Engineering 2019年第5期13卷 1036-1053页

作者： ning ZHANG Xu LI Qinghui jiang Xingchao LIN School of Civil Engineering Beijing Jiaotong UniversityBeijing 100044China Key Laboratory of Urban Underground Engineering of Ministry of Education Beijing Jiaotong UniversityBeijing 100044China School of Civil and Architectural Engineering Wuhan UniversityWuhan 430072China State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin Beijing 100038China

Numerical manifold method (NMM) is an effective method for simulating block system, however, significant errors are found in its simulation of rotation problems. Three kinds of errors, as volume expansion, stress vibration, and attenuation of angular velocity, were observed in the original NMM. The first two kind errors are owing to the small deformation assumption and the last one is due to the numerical damping. A large deformation NMM is proposed based on large deformation theory. In this method, the governing equation is derived using Green strain, the large deformation iteration and the open-close iteration are combined, and an updating strategy is proposed. The proposed method is used to analyze block rotation, beam bending, and rock falling problems and the results prove that all three kinds of errors are eliminated in this method.

关键词： numerical manifold method rotation large deformation Green strain open-close iteration

THE EXISTENCE OF A BOUNDED INVARIANT REGION FOR COMPRESSIBLE EULER EQUATIONS IN DIFFERENT GAS STATES

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Acta Mathematica Scientia 2020年第5期40卷 1229-1239页

作者： Weifeng jiang zhen WANG College of Science China Jiliang UniversityHangzhou 310018China College of Science Wuhan University of TechnologyWuhan 430071China

In this article,by the mean-integral of the conserved quantity,we prove that the one-dimensional non-isentropic gas dynamic equations in an ideal gas state do not possess a bounded invariant ***,we obtain a necessary condition on the state equations for the existence of an invariant region for a non-isentropic ***,we provide a mat hematical example showing that with a special state equation,a bounded invariant region for the non-isentropic process may exist.

关键词： Euler equations gas dynamic non-isentropic existence of invariant region

Remarks on One-Dimensional Compressible Navier-Stokes Equations with Density-Dependent Viscosity and Vacuum

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Acta Mathematica Sinica,English Series 2010年第10期26卷 2015-2030页

作者： zhen Hua GUO Chang jiang ZHU Center for Nonlinear Studies and Department of Mathematics Northwest University Xi'an 710069 P. R. China Laboratory of Nonlinear Analysis Department of Mathematics Central China Normal University Wuhan 4300794 P. R. China

The Navier-Stokes system for one-dimensional compressible fluids with density-dependent viscosities when the initial density connects to vacuum continuously is considered in the present paper. When the viscosity coefficient u is proportional to pθ with 0 〈 θ 〈 1, the global existence and the uniqueness of weak solutions are proved which improves the previous results in [Vong, S. W., Yang, T., Zhu, C. J.： Compressible Navier-Stokes equations with degenerate viscosity coefficient and vacuum II. J. Differential Equations, 192（2）, 475-501 （2003）]. Here p is the density. Moreover, a stabilization rate estimate for the density as t → ＋∞ for any θ 〉 0 is also given.

关键词： Compressible Navier-Stokes equations density-dependent viscosity vacuum asymptotic behavior

Ultrastructural Changes in the Interaction Between Puccinia striiformis and Wheat Cultivar with Slow-Rusting Resistance

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Agricultural Sciences in China 2010年第1期9卷 64-70页

作者： jiang Xuan-li KANG zhen-sheng Department of Plant Protection Agricultural College Guizhou University Guiyang 550025 P.R.China Plant Protection College Northwest A&F University Yangling 712100 P.R.China

Ultrastructural changes in both pathogen and host cells in the interaction between Puccinia striiformis and wheat cultivar （Libellula） with slow-rusting resistance were observed by transmission electron microscopy. Observations revealed marked changes in ultrastructure of both pathogen and host cells. In the pathogen respect, there were many vesicles appeared in the intercellular hyphae and gradually fused into bigger vacuoles, a number of fat drops and electron-dense granules accumulated, mitochondria became swollen and some of them degraded into vesicles, and the plasmalemma of intercellular hyphae became dark. In the haustoria, the cytoplasm degraded gradually and developed a vacuole in the center, fat drops increased, the extrahaustorial matrix widened with a great amount of electron-dense fibrillar and granular materials, and most of the haustoria died with in conjunction with the disappearance of fat drops and other organelles. Structural defense of the host, including formation of cell wall apposition, collar and papilla, occurred in the host respect. Host resistance expression and cytological features occurring in the slow-rusting resistance were discussed.

关键词： wheat Puccinia striiformis ultrastructure slow-rusting resistance

Energy-Preserving Parareal-RKN Algorithms for Hamiltonian Systems

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Numerical Mathematics(Theory,Methods and Applications) 2024年第1期17卷 121-144页

作者： zhen Miao Bin Wang Yaolin jiang School of Mathematics and Statistics Northwestern Polytechnical UniversityXi’an 710072P.R.China School of Mathematics and Statistics Xi’an Jiaotong UniversityXi’an 710049P.R.China

In this paper,we formulate and analyse a kind of parareal-RKN algo-rithms with energy conservation for Hamiltonian *** proposed algorithms are constructed by using the ideas of parareal methods,Runge-Kutta-Nystrom(RKN)methods and projection *** is shown that the algorithms can exactly pre-serve the energy of Hamiltonian ***,the convergence of the integra-tors is rigorously *** numerical experiments are carried out to support the theoretical results presented in this paper and show the numerical behaviour of the derived algorithms.

关键词： Parareal methods Runge-Kutta-Nystrom methods Hamiltonian systems energy conservation