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综合护理在女性老年高血压脑出血中的应用效果

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妇儿健康导刊 2024年第3期3卷 172-174,178页

作者：刘妮娜辛海滨山东省安丘市人民医院老年病科山东安丘262100 山东省安丘市人民医院神经外科山东安丘262100

目的探究综合护理在女性老年高血压脑出血中的应用效果。方法选取安丘市人民医院2019年10月至2022年10月收治的62例女性老年高血压脑出血患者作为研究对象,按照随机数字表法分为对照组(n=31)和观察组(n=31)。对照组采用常规护理,观察组... 详细信息

目的探究综合护理在女性老年高血压脑出血中的应用效果。方法选取安丘市人民医院2019年10月至2022年10月收治的62例女性老年高血压脑出血患者作为研究对象,按照随机数字表法分为对照组(n=31)和观察组(n=31)。对照组采用常规护理,观察组采用综合护理,比较两组心理状态、日常生活能力及并发症发生情况。结果护理后,观察组抑郁自评量表、焦虑自评量表评分均低于对照组(P<0.05);观察组日常生活能力评定量表评分高于对照组(P<0.05);观察组并发症总发生率低于对照组(P<0.05)。结论女性老年高血压脑出血患者采用综合护理可调节心理状态,提高日常生活能力,减少并发症。

关键词：综合护理高血压脑出血老年女性

A survey of energy-efficient strategies for federated learning in mobile edge computing

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Frontiers of Information Technology & Electronic Engineering 2024年第5期25卷 645-663页

作者： Kang YAN nina SHU Tao WU Chunsheng liu Panlong YANG School of Electronic Engineering National University of Defense TechnologyHefei 230009China Department of Computing Hong Kong Polytechnic UniversityHong Kong 999077China School of Computer Science and Technology University of Science and Technology of ChinaHefei 230026China

With the booming development of fifth-generation network technology and Internet of Things,the number of end-user devices(EDs)and diverse applications is surging,resulting in massive data generated at the edge of *** process these data eficiently,the innovative mobile edge computing(MEC)framework has emerged to guarantee low latency and enable eficient computing close to the user ***,federated learning(FL)has demonstrated its empirical success in edge computing due to its privacy-preserving ***,it becomes a promising solution for analyzing and processing distributed data on EDs in various machine learning tasks,which are the major workloads in ***,EDs are typically powered by batteries with limited capacity,which brings challenges when performing energy-intensive FL *** address these challenges,many strategies have been proposed to save energy in *** the absence of a survey that thoroughly summarizes and classifies these strategies,in this paper,we provide a comprehensive survey of recent advances in energy-efficient strategies for FL in ***,we first introduce the system model and energy consumption models in FL,in terms of computation and *** we analyze the challenges regarding improving energy efficiency and summarize the energy-efficient strategies from three perspectives:learning-based,resource allocation,and client *** conduct a detailed analysis of these strategies,comparing their advantages and ***,we visually illustrate the impact of these strategies on the performance of FL by showcasing experimental ***,several potential future research directions for energy-efficient FL are discussed.

关键词： Mobile edge computing Federated learning Energy-efficient

蛇伤膏外敷治疗毒蛇咬伤火毒证的疗效观察与网络药理学机制研究

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山西中医药大学学报 2024年第1期25卷 68-76页

作者：袁晨钱自华汪四海刘妮娜胡鹏安徽中医药大学安徽合肥230012 安徽中医药大学第一附属医院急诊科安徽合肥230031

目的:观察蛇伤膏外敷治疗毒蛇咬伤火毒证患者的临床疗效,运用网络药理学方法及分子对接技术分析蛇伤膏治疗毒蛇咬伤潜在的作用机制。方法:选取安徽中医药大学第一附属医院入诊的毒蛇咬伤火毒证患者60例,随机分为对照组和试验组,每组30... 详细信息

目的:观察蛇伤膏外敷治疗毒蛇咬伤火毒证患者的临床疗效,运用网络药理学方法及分子对接技术分析蛇伤膏治疗毒蛇咬伤潜在的作用机制。方法:选取安徽中医药大学第一附属医院入诊的毒蛇咬伤火毒证患者60例,随机分为对照组和试验组,每组30例。对照组采用常规中医适宜技术治疗,试验组在对照组治疗基础上采用蛇伤膏外敷治疗。观察两组患者临床疗效、症状与体征积分、疼痛与肿胀程度评分、中性粒细胞百分比(NEUT%)、凝血酶原时间(PT)、C反应蛋白(CRP)、白细胞介素-6(IL-6)水平;基于药物与疾病数据库筛选蛇伤膏-毒蛇咬伤靶点及共有靶点,利用DAVID平台进行基因本体(GO)功能分析和京都基因与基因组百科全书(KEGG)通路富集分析,运用Cytoscape构建蛋白相互作用网络(PPI)并筛选关键基因与靶点,利用AutoDockPools1.5.7进行分子对接及PyMol可视化。结果:两组患者临床疗效有效率均为100%,试验组治愈率(67%,20/30例)高于对照组(27%,8/30例),差异有统计学意义(P<0.01);与治疗前比较,试验组治疗后症状与体征积分、疼痛与肿胀程度评分、NEUT、PT、CRP、IL-6水平均下降,差异有统计学意义(P<0.01);两组患者治疗后比较,试验组肿胀程度评分、NEUT均低于对照组,差异有统计学意义(P<0.05),临床疗效、疼痛评分、肢体症状与体征评分、PT、CRP、IL-6指标均明显低于对照组,差异有统计学意义(P<0.01);网络药理学分析显示,蛇伤膏-毒蛇咬伤的核心靶点为表皮生长因子(EGF)、表皮生长因子受体(EGFR)、纤连蛋白1(FN1)、白细胞介素-6(IL-6)、基质金属蛋白酶9(MMP9)、转化生长因子β1(TGF-β1)、肿瘤坏死因子(TNF),核心成分包括槲皮素、黄芩素、木犀草素、汉黄芩素等,主要涉及MAP激酶活性的正调节、细胞外空间、蛋白酶结合、AGE/RAGE通路、TNF等生物功能与信号通路,分子对接结果良好。结论:蛇伤膏治疗毒蛇咬伤火毒证效果显著;网络药理学初步探究了蛇伤膏通过多靶点、多通路途径治疗毒蛇咬伤,与临床相关指标具有联系性,为后续研究提供理论与依据。

关键词：毒蛇咬伤火毒证蛇伤膏中药外敷网络药理学

应用CiteSpace和VOSviewer对蛇咬伤临床研究的文献计量学研究

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齐齐哈尔医学院学报 2024年第16期45卷 1515-1523页

作者：李超君徐海霞马文静李梦缘刘妮娜安徽中医药大学安徽合肥2300312 安徽中医药大学第一附属医院安徽合肥230031

目的应用CiteSpace和VOSviewer软件对蛇咬伤领域的研究现状、热点及趋势进行可视化分析。方法采用文献计量学方法从Web of Science核心库中收集相关文献,并使用CiteSpace和VOSviewer进行数据可视化和分析。结果通过446篇相关文献研究,... 详细信息

目的应用CiteSpace和VOSviewer软件对蛇咬伤领域的研究现状、热点及趋势进行可视化分析。方法采用文献计量学方法从Web of Science核心库中收集相关文献,并使用CiteSpace和VOSviewer进行数据可视化和分析。结果通过446篇相关文献研究,发现蛇咬伤的临床研究主要集中在蛇咬伤的治疗与护理、预防与控制、诊断与治疗以及蛇毒成分。其中,蛇毒成分的研究最为热门,而蛇咬伤患者的临床治疗与护理管理则是重点研究方向。结论本研究系统分析了蛇咬伤临床研究的趋势和热点,为今后蛇咬伤的临床决策和急诊医学研究提供进一步参考。

关键词：蛇伤护理蛇伤治疗研究热点可视化分析 CiteSpace VOSviewer

Inversion of the paleo-geothermal gradient using low-temperature thermochronology: A case study of the Haiyuan -liupanshan region

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Journal of Earth Science 2023年

作者： Ruxin Ding Zhenghai Wang Kyoungwon Min nina liu Cleber Soares Jing liu-Zeng Weitao Wang School of Earth System Science Tianjin University Guangdong Provincial Key Lab of Geodynamics and Geohazards School of Earth Sciences and Engineering Sun Yat-sen University Key Laboratory of Western China's Mineral Resource and Geological Engineering Ministry of Education Chang'an University 6. ChronusCamp Research-Thermochronology Analysis LTD Guangdong Provincial Key Laboratory of Mineral Resources & Geological Processes Department of Geological Sciences University of Florida Southern Laboratory of Ocean Science and Engineering

The paleo-geothermal gradient is a crucial parameter for converting the thermal history to the exhumation history. However， the precise estimation of this parameter has been a challenge. This paper presents a simple two-step method to model the paleo-geothermal gradient using low-temperature thermochronology. (1) It uses the Monte Carlo approach to generate thermal histories in a vertical section randomly and calculates the entire thermal history within the goodness-of-fit thresholds based on different paleo-geothermal gradients. (2) It selects the optimum paleo-geothermal gradient by comparing the entire thermal history within different goodness-of-fit thresholds. We validated the method with apatite (U-Th)/He and fission track data collected from two drill cores in the Haiyuan-liupanshan region. The result revealed that the best-fit paleo-geothermal gradient was ～42 ℃/km during the Early Cretaceous–Miocene and has decreased rapidly to 20 ℃/km since ～10 Ma. The crust thickening in the study area may explain the rapid reduction in the paleo-geothermal gradient since ～10 Ma. Our results are consistent with earlier studies in the region， suggesting that our simple and more intuitive approach provides an alternative method for paleo-geothermal gradient modeling.

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中医外治单元疗法治疗胡蜂蜇伤的疗效观察

安徽医学 2024年第6期45卷 701-705页

作者：胡鹏钱自华刘妮娜徐桂琴王凯曹承楼安徽中医药大学第一附属医院急诊科安徽合肥230031 安徽中医药大学第一附属医院科研部安徽合肥230031

目的观察中医外治单元疗法对胡蜂蜇伤急诊患者的疗效。方法将2021年4月至2023年9月安徽中医药大学第一附属医院急诊科收治的70例胡蜂蜇伤患者采用随机数字表法分为观察组与对照组,各35例。对照组采用基础治疗方法,观察组在对照组基础上... 详细信息

目的观察中医外治单元疗法对胡蜂蜇伤急诊患者的疗效。方法将2021年4月至2023年9月安徽中医药大学第一附属医院急诊科收治的70例胡蜂蜇伤患者采用随机数字表法分为观察组与对照组,各35例。对照组采用基础治疗方法,观察组在对照组基础上加用中医外治单元疗法,疗程为5 d。比较两组患者治疗前后疗效、数字疼痛评分(NRS)和毒效应指标[天门冬氨酸氨基转移酶/丙氨酸氨基转移酶(AST/ALT)、总胆红素(TBIL)、肌酐(SCr)、部分凝血酶原时间(APTT)、超敏C反应蛋白(hs-CRP)],并记录两组蜇伤处肿胀开始消退时间。结果观察组总有效率(85.71%)高于对照组(62.86%),肿胀消退时间短于对照组,差异有统计学意义(P<0.05)。两组患者治疗前后NRS评分、AST/ALT、TBIL、SCr、APTT、hs-CRP差值比较,差异均有统计学意义(P<0.05)。结论中医外治单元疗法能加速胡蜂蜇伤局部肿胀消退,缓解疼痛,降低毒效应指标,促进炎症吸收,加速患者康复。

关键词：胡蜂蜇伤刺血拔罐耳穴贴压中药外敷

Mechanochemical route to fabricate an efficient nitrate reduction electrocatalyst

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Nano Research 2024年第6期17卷 4889-4897页

作者： Yunliang liu Zhiyu Zheng Sobia Jabeen Naiyun liu Yixian liu Yuanyuan Cheng Yaxi Li Jingwen Yu Xin Wu nina Yan Lei Xu Haitao Li Institute for Energy Research School of Energy and Power EngineeringJiangsu UniversityZhenjiang 212013China Jiangsu Engineering Technology Research Center of Biomass Composites and Addictive Manufacturing Institute of Agricultural Facilities and EquipmentJiangsu Academy of Agricultural SciencesNanjing 210014China Key Laboratory for Protected Agricultural Engineering in the Middle and Lower Reaches of Yangtze River Ministry of Agriculture and Rural AffairsNanjing 210014China

The electrochemical nitrate reduction reaction(NO_(3)RR)to ammonia under ambient conditions is a promising approach for addressing elevated nitrate levels in water bodies,but the progress of this reaction is impeded by the complex series of chemical reactions involving electron and proton transfer and competing hydrogen evolution ***,it becomes imperative to develop an electro-catalyst that exhibits exceptional efficiency and remarkable selectivity for ammonia synthesis while maintaining long-term *** the magnetic biochar(Fe-C)has been synthesized by a two-step mechanochemical route after a pyrolysis treatment(450,700,and 1000℃),which not only significantly decreases the particle size,but also exposes more oxygen-rich functional groups on the surface,promoting the adsorption of nitrate and water and accelerating electron transfer to convert it into *** showed that the catalyst(Fe-C-700)has an impressive NH_(3)production rate of 3.5 mol·h^(−1)·gcat^(−1),high Faradaic efficiency of 88%,and current density of 0.37 A·cm^(−2)at 0.8 V *** hydrogen electrode(RHE).In-situ Fourier transform infrared spectroscopy(FTIR)is used to investigate the reaction intermediate and to monitor the *** oxygen functionalities on the catalyst surface activate nitrate ions to form various intermediates(NO_(2),NO,NH_(2)OH,and NH_(2))and reduce the rate determining step energy barrier(*NO_(3)→*NO_(2)).This study presents a novel approach for the use of magnetic biochar as an electro-catalyst in NO_(3)RR and opens the road for solving environmental and energy challenges.

关键词： mechanochemical route magnetic biochar electron transfer nitrate ammonia

Co-Seismic Surface Rupture and Recurrence Interval of Large Earthquakes along Damaoyaba-Litang Segment of the Litang Fault on the Eastern Margin of the Tibetan Plateau in China

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Journal of Earth Science 2021年第5期32卷 1139-1151页

作者： Shiyuan Wang Rongjun Zhou Mingjian Liang Shao liu nina liu Jianyu Long Sichuan Earthquake Agency^Chengdu 610041 China School of Geological Engineering and Geomatics Chang'an UniversityXi'an 710054China

The Litang fault is a left-lateral secondary shear zone in the Sichuan-Yunnan active block that accommodates the tectonic deformation associated with the eastward extrusion of the upper crust of the Tibetan Plateau. Based on 1 : 50 000 geological mapping of active faults, the Litang fault consists of three geometric segments, the Cuopuhu, Damaoyaba, and Litang segments, in the west of Litang, which are divided by the of Haizi Mountain uplift and the wide-angle bending and branching of the fault near Jinchanggou. This study also identifies the surface rupture of the A.D. 1890 earthquake, which is distributed intermittently along the ~28 km long Damaoyaba segments and ~25 km long Litang segments. The maximum horizontal displacement is 4.1 m along Damaoyaba segments, and 4 m along Litang segments. The rupture involves typical left-lateral shear movement. The two ruptures are divided by discontinuous segments or gaps that are ~18 km long;thus, the total surface rupture is approximately 71 km long. The estimated moment magnitude was M_(w)7.3±0.1. A comprehensive analysis of data obtained from 5 trenches excavated along the Damaoyaba and Litang segments and the trench data by Xu et al.(2005) identifies age constraints of the 4 most recent paleoseimic events occurred B.C. 1468±54–1340±25, B.C. 52±25–A.D. 76±47, A.D. 1115±90, and A.D. 1890, respectively. The recurrence intervals are 1 415±80, 1 104±104, and 775±90 a, which are consistent with quasi-periodic earthquake recurrence behavior. The average recurrence interval is 1 098±112 a.

关键词： Litang fault surface rupture active fault recurrence intervals paleoearthquake eastern Tibetan Plateau

Mechanism of hypothalamic paraventricular nucleus in regulating asthmatic attack

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Neural Regeneration Research 2006年第7期1卷 593-596页

作者： Jia liu Rong Dong Jian Xiao nina liu Department of Physiology and Pharmacology School of Basic Medical SciencesSoutheast UniversityNanjing 210009Jiangsu ProvinceChina

BACKGROUND:It has been confirmed that c-fos expression increased markedly in hypothalamic paraventricular nucleus(PVN)during asthmatic attack in rats,and PVN has extensive physiological functions,involving in the regulation of respiratory system,***:To observe the alteration of electroencephalogram(EEG)and power spectra in PVN during the asthmatic attack,and the alteration of lung function and diaphragmatic muscle discharge after bilateral PVN lesion in asthmatic ***:A randomized control ***:Laboratory of Physiology and Pharmacology,School of Basic Medical Sciences,Southeast ***:Forty-eight male adult SD rats of 260-300 g were *** rats were randomly divided into 6 groups(n=8):control group,asthma group,electrolytic lesion of PVN group,KA-induced lesion of PVN group,sham electrolytic lesion of PVN group and sham kainic acid(KA)-induced lesion of PVN ***,chicken ovalbumin and aluminum hydroxide were purchased from American Sigma *** pertussis vaccine(Institute of Biological Products of Shanghai);stereotaxic apparatus(JiangwanⅡ,China);lesion-producing device(YC-2 programmable stimulato,Chengdu Instrument Company);MD2000 signal processing system(Nanjing Medical School);data acquisition system(RM6240B,Chengdu Instrument Company).METHODs:The experiments were carried out in the Laboratory of Physiology and Pharmacology,School of Basic Medical Sciences,Southeast University from January to August in 2006.①Rats except for control group were sensitized with an intraperitoneal injection of 100 mg chicken ovalbumin and 100 mg aluminum hydroxide and Bordetella pertussis vaccine containing 5×10^(9) heat-killed in 1 mL of sterile *** the fifteenth to seventeenth days rats received three times aerosolized ovalbumin *** rats of the control group and asthma group three steel electrodes were placed into the left PVN(AP-1.8 mm,LR 0.4 mm,OH-7.9 mm),parietal cortex and subcutaneous tissue in lower limb.

关键词： PVN Mechanism of hypothalamic paraventricular nucleus in regulating asthmatic attack