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World Journal of Clinical Cases 2021年第27期9卷 8164-8170页

作者： Xiu-Li Wang Yue Du Cheng-guang Zhao Yu-Bin Wu ni Yang Liang Pei Li-Jie Wang Qiu-Shi Wang Department of Pediatrics Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina Department of Blood Transfusion Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

BACKGROUND The occurrence of Streptococcus pneumoniae-associated hemolytic uremic syndrome(SP-HUS)is ***-Friedenreich antigen activation is highly involved in the pathogenesis of SP-HUS,and T-antibody-negative plasma exchange(PE)may be effective in the treatment of severe cases of *** SUMMARY We retrospectively reviewed two pediatric patients with *** clinical features and laboratory examination results of the children were ***-negative PE was performed in both *** children made a full recovery after repeated PE and remained well at a 2 year *** Streptococcal pneumonia continues to be an uncommon but important cause of *** successful treatment of the presented cases suggests that T-antibodynegative PE may benefit patients with SP-HUS.

关键词： Streptococcus pneumoniae Hemolytic uremic syndrome Children Plasma exchange Thomsen-Friedenreich antigen exposure Case report

Role of Cluster Geometry in Evolution of Electronic Structures of Small Aluminum Clusters

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Chinese Physics Letters 1997年第12期14卷 897-900页

作者： ZHAI Hua-jin ZHAO Ji-jun ni Guo-quan ZHOU Ru-fang WANG guang-hou WANG Yu-zhu Laboratory for Quantum Optics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800 Department of Physics and National Laboratory of Solid State Microstructures Nanjing UniversityNanjing 210093

The electronic structures of small aluminum clusters,Al_(n)(n=5-24),are investigated by a localized-orbital theory based on the tight-binding ***-numbered clusters each exhibit a HOMO-LUMO gap maximum,and simultaneously an s-p gap minimum,but not necessarily an ionization potential maximum,where HOMO-LUMO gap denotes the energy gap between the highest occupied orbital and the lowest unoccupied orbital of the *** revealed is an irregular odd-even alternation in HOMO-LUMO gaps for Al_(n)(n=7-24).Cluster geometry either contributes to or dominates these findings.

关键词： cluster orbital occupied

Food allergy and related risk factors in 2540 preschool children: an epidemiological survey in guangdong Province, southern China

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World Journal of Pediatrics 2015年第3期11卷 219-225页

作者： guang-Qiao Zeng Jia-Ying Luo Hui-Min Huang Pei-Yan Zheng Wen-Ting Luo ni-Li Wei Bao-Qing Sun State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseasesGuangzhou Institute of Respiratory DiseasesFirst Affiliated HospitalGuangzhou Medical UniversityGuangzhouChina

Background:Although the number of studies on allergic diseases in the general population of southern China is increasing,only a few have addressed food allergy(FA)in children in this *** present study aimed to investigate the prevalence,clinical manifestations,spectrum of allergens,and related risk factors of FA in preschool children in guangdong Province,southern ***:A random cluster-sampling method was used to select 24 kindergartens from 12 cities in guangdong *** parents or guardians of the children were requested to complete a questionnaire on general information and data regarding FA diagnosis and symptoms in the children and their first-degree ***,the Chi-square test,multivariate regression analysis,and Spearman's rank-order correlation coefficient analysis were performed to identify statistically significant ***:Analysis of 2540 valid questionnaires revealed an FA prevalence rate of 4%.Adverse food reactions were due to the consumption of shrimp(4.4%),crab(3.2%),mango(2.3%),cow's milk and dairy products(1.9%),and eggs(1.4%).Logistic regression analysis indicated that a history of FA and a history of allergic rhinitis in the first-degree relatives were the major factors leading to FA in ***:The incidence of FA in children in guangdong Province is higher than that commonly *** individual's genetic background is an important risk factor for ***,mitigation of the impact of lifestyle and environmental factors should be carefully considered to reduce the incidence of childhood FA.

关键词： allergic rhinitis eczema epidemiology food allergy questionnaire

Accumulation Pattern of Jurassic Tight Oil in Sichuan Basin and Its Exploration & Development Prospect

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Acta Geologica Sinica(English Edition) 2015年第A1期89卷 258-260页

作者： LI Yaohua YANG guang TAO Shizhen ni Chao CHEN Shijia LI Zhou Exploration and Development Research Institute PetroChina Southwest Oil and Gasfield Company Chengdu Sichuan610041 PetroChina Research Institute of Petroleum Exploration & Development Beijing 100083 PetroChina Hangzhou Research Institute of Geology Hangzhou Zhejiang 310023 School of Geoscience and Technology Southwest Petroleum University Chengdu Sichuan 610500

Jurassic tight oil in Sichuan Basin is chiefly distributed over the central basin with an area of about 4.2×10^4 km2. Since the first drilling in 1953, it has experienced four stages, including the Central Sichuan Basin Brought under Exploration and Development, Progressive Exploration and Development, Setting A Goal of 30×10^4 t/a, and Adjusting and Keeping A Stable Production.

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适用于不确定类标签数据学习的迁移支持向量机

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控制与决策 2014年第10期29卷 1751-1757页

作者：倪彤光王士同江南大学数字媒体学院江苏无锡214122 常州大学信息科学与工程学院江苏常州213164

为了解决包含不确定信息的分类学习问题,提出一种新的适用于不确定类标签数据的迁移支持向量机.该方法基于结构风险最小化模型,同时将源领域中所学知识、领域间的共享数据、目标领域中已标定的和不确定的数据纳入学习框架中,进而实现了... 详细信息

为了解决包含不确定信息的分类学习问题,提出一种新的适用于不确定类标签数据的迁移支持向量机.该方法基于结构风险最小化模型,同时将源领域中所学知识、领域间的共享数据、目标领域中已标定的和不确定的数据纳入学习框架中,进而实现了源领域和目标领域的知识迁移.在多种真实数据集上的实验结果表明了所提出方法的有效性.

关键词：迁移学习分类支持向量机共享数据不确定数据

Removal of tungsten and vanadium from molybdate solutions using ion exchange resin

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Transactions of Nonferrous Metals Society of China 2017年第12期27卷 2727-2732页

作者： Xian-zheng ZHU guang-sheng HUO Jie ni Qiong SONG School of Metallurgy and Environment Central South University Changsha 410083 China

The removal of tungsten(W)and vanadium(V)from molybdate solutions was studied using the poly hydroxyl chelating resin D403in batch and column *** batch experiments indicated that tungsten and vanadium could be preferentially adsorbed by the D403resin for4h in molybdate solution at a pH of *** factors,αVMo andαWMo,wereabove45and18,respectively,when the molar ratios of Mo/V and Mo/W in the solution *** tests illustrated that vanadium and tungsten could be easily eluted from the resin with1mol/L sodium hydroxide solution in *** further explore the sorption mechanism of the resin,the experimental equilibrium isotherm data of the three metals fitted well with the Freundlich *** column experiments confirmed the adaptability of the D403resin in the production of sodium molybdate with a removal rate of tungsten surpassing90%and that of vanadium of99.4%.

关键词： tungsten vanadium removal ion exchange molybdate

MicroRNA profiling of the intestine during hypothermic circulatory arrest in swine

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World Journal of Gastroenterology 2015年第7期21卷 2183-2190页

作者： Wei-Bin Lin Meng-Ya Liang guang-Xian Chen Xiao Yang Han Qin Jian-Ping Yao Kang-ni Feng Zhong-Kai Wu 2~(nd) Department of Cardiac Surgery the First Affiliated Hospital of Sun Yat-Sen University

AIM:To perform a profiling analysis of changes in intestinal micro RNA(mi RNA)expression during hypothermic circulatory arrest(HCA).METHODS:A total of eight piglets were randomly divided into HCA and sham operation(SO)*** general anesthesia,swine in the HCA group were subjected to hypothermic cardiopulmonary bypass at 24?℃followed by 80 min of circulatory arrest,and the reperfusion lasted for 180 min after cross-clamp *** counterparts in the SO group were only subjected to median *** analysis was used to detect mucosal injury,and Pickand-Mix custom mi RNA real-time polymerase chain reaction(PCR)panels containing 306 unique primer sets were utilized to assay unpooled intestinal samples harvested from the two ***:The intestinal mucosa of the animals that were subjected to 24?℃HCA exhibited representative ischemic reperfusion injury of grade 2 or 3 according to the Chiu *** intestinal mucosal injuries,with the subepithelial space and epithelial layer lifting away from the lamina propria,were accompanied by shortened and irregular *** the contrary,the intestinal mucosa remained normal in the shamoperated *** total,twenty-five mi RNAs were differentially expressed between the two groups(15upregulated and 10 downregulated in the HCA group).Among these,eight mi RNAs(mi R-122,mi R-221-5p,mi R-31,mi R-421-5p,mi R-4333,mi R-499-3p,mi R-542and let-7d-3p)were significantly dysregulated(four higher and four lower).The expression of mi R-122 was significantly(5.37-fold)increased in the HCA group vs the SO group,indicating that it may play a key role inHCA-induced mucosal ***:Exposure to HCA caused intestinal mi RNA dysregulation and barrier dysfunction in *** altered mi RNAs might be related to the protection or destruction of the intestinal barrier.

关键词： Reperfusion injury Cardiopulmonary bypass Animal m

磁流变阻尼器对火炮后坐炮膛时期阻尼特性分析

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振动与冲击 2019年第20期38卷 172-180,187页

作者：张广汪辉兴王炅南京理工大学机械工程学院

磁流变胶(Magnetorheological Gel,MRG)与磁流变液(Magnetorheological Fluid,MRF)相比具有一定的抗沉降性和超长的稳定性。因此,MRG非常适用于像火炮等在和平时期长时间储藏后其各方面性能仍能满足作战要求的一类武器的反后坐应用中。... 详细信息

磁流变胶(Magnetorheological Gel,MRG)与磁流变液(Magnetorheological Fluid,MRF)相比具有一定的抗沉降性和超长的稳定性。因此,MRG非常适用于像火炮等在和平时期长时间储藏后其各方面性能仍能满足作战要求的一类武器的反后坐应用中。为了深入研究MRG微观磁-力学特性对阻尼器宏观输出阻尼力学影响的机理,建立了库埃特(Couette)剪切流动和泊肃叶(Poiseuille)压力流动组成的混合流动模式的平行板模型;对阻尼器输出阻尼展开理论分析,最后利用MRG-70力学参数对阻尼器应用在火炮反后坐炮膛时期的可控性展开初步分析。分析结果表明:阻尼器的阻尼系数随MRG-70的动力黏度ηB、活塞有效工作截面积A P、磁极长度L以及Bingham系数Bi的增大而增大;而随阻尼通道y轴宽度d的二次方及屈服前柱塞流动y轴方向无量纲宽度δm增大而减小。磁流变阻尼器对火炮后坐炮膛时期具有可控性,且在能量输入非常小(0~131 mT)的情况下能达到较宽的可控范围。

关键词：磁流变胶反后坐阻尼系数混合流动

Chemiluminescent carbon nanodots for dynamic and guided antibacteria

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Light(Science & Applications) 2023年第5期12卷 915-927页

作者： Jiang-Fan Han Qing Lou Zhong-Zheng Ding guang-Song Zheng Qing-Chao ni Run-Wei Song Kai-Kai Liu Jin-Hao Zang Lin Dong Cheng-Long Shen Chong-Xin Shan Henan Key Laboratory of Diamond Optoelectronic Materials and Devices Key Laboratory of Material PhysicsMinistry of EducationSchool of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China

Advanced antibacterial technologies are needed to counter the rapid emergence of drug-resistant *** therapy is one of the most promising strategies for efficiently and accurately curing bacterial ***,a chemiluminescence(CL)-dynamic/guided antibacteria(CDGA)with multiple reactive oxygen species(ROS)generation capacity and chemiexcited near-infrared emission has been designed for the precise theranostics of bacterial infection by employing near-infrared emissive carbon nanodots(CDs)and peroxalate as CL ***,hydrogen peroxide generated in the bacterial microenvironment can trigger the chemically initiated electron exchange between CDs and energy-riched intermediate originated from the oxidized peroxalate,enabling bacterial induced inflammation ***,type Ⅰ/Ⅱ photochemical ROS production and type Ⅲ ultrafast charge transfer from CDs under the self-illumination can inhibit the bacteria proliferation *** potential clinical utility of CDGA is further demonstrated in bacteria infected mice trauma *** self-illuminating CDGA exhibits an excellent in vivo imaging quality in early detecting wound infections and internal inflammation caused by bacteria,and further are proven as efficient broad-spectrum antibacterial nanomedicines without drug-resistance,whose sterilizing rate is up to 99.99%.

关键词： dynamic illumination initiated

Allele-specific expression and alternative splicing in horse×donkey and cattle×yak hybrids

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Zoological Research 2019年第4期40卷 293-304页

作者： Yu Wang Shan Gao Yue Zhao Wei-Huang Chen Jun-Jie Shao ni-ni Wang Ming Li guang-Xian Zhou Lei Wang Wen-Jing Shen Jing-Tao Xu Wei-Dong Deng Wen Wang Yu-Lin Chen Yu Jiang Key Laboratory of Animal Genetics Breeding and Reproduction of Shaanxi ProvinceCollege of Animal Science and TechnologyNorthwest A&F UniversityYangling Shaanxi 712100China Stake Key Laboratory of Plateau Ecology and Agriculture Qinghai Academy of Animal Science and Veterinary MedicineQinghai UniversityXining Qinghai 810016China State Key Laboratory of Genetic Resources and Evolution Kunming Institute of ZoologyChinese Academy of SciencesKunming Yunnan 650223China Faculty of Animal Science and Technology Yunnan Agricultural UniversityKunming Yunnan 650223China

Divergence of gene expression and alter native splicing is a crucial driving force in the evolution of species;to date, however the molecular mechanism remains unclear. Hybrids of closely related species provide a suitable model to analyze allele-specific expressi on (ASE) and allele-specific alter native splicing (ASS). Analysis of ASE and ASS can uncover the differences in cis-regulatory elements between closely related species, while eliminating interferenee of trans-regulatory elements. Here, we provide a detailed characterization of ASE and ASS from 19 and 10 transcriptome datasets across five tissues from reciprocal-cross hybrids of horsex don key (mule/hi nny) and cattlexyak (dzo), respectively. Results showed that 4.8%-8.7% and 10.8%-16.7% of genes exhibited ASE and ASS, respectively. Notably, IncRNAs and pseudogenes were more likely to show ASE than protein-coding genes. In addition, genes showing ASE and ASS in mule/hinny were found to be involved in the regulation of muscle strength, whereas those of dzo were involved in high-altitude adaptati on. In con clusi on, our study dem on strated that explorati on of genes showing ASE and ASS in hybrids of closely related species is feasible for species evolution research.

关键词： Allele-specific alternative splicing Allele-specific expression Cis-regulatory elements Hybrid species