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Ardisia gigantifolia ethanolic extract inhibits cell proliferation and targets cancer stem cells in gastric cancer

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Asian Pacific Journal of Tropical Biomedicine 2023年第6期13卷 258-267页

作者： Thi thanh Huong Le Phu Hung nguyen Van Phuong nguyen Thy Ngoc nguyen Faculty of Biotechnology TNU-University of SciencesThai NguyenVietnam Department of Life Science University of Science and Technology of HanoiVietnam Academy of Science and TechnologyHanoiVietnam

Objective:To evaluate the effects of ethanol extract from Ardisia gigantifolia leaves on cell proliferation and cancer stem cell(CSC)number in gastric ***:The inhibitory effect of Ardisia gigantifolia extract on the proliferation of MKN45 and MKN74 gastric cancer cells was assessed using 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide ***-adherent culture(3D)model was used to evaluate the effect of the extract on tumorsphere size and ***,the expression of CD44,ALDH,and p21 was determined by immunofluorescence *** cytometric analysis was performed to evaluate cell cycle arrest and the expression of gastric CSC markers CD44 and ***-time PCR analysis was also carried out to assess the effect of the extract on the expression of cell cycle-regulated ***:Ardisia gigantifolia extract effectively inhibited cell proliferation with an IC_(50)of 55.7μg/m L in MKN45 cells and 123.6μg/m L in MKN74 *** extract also arrested cell cycle in the G_(0)/G_(1)phase as well as significantly reduced the size and number of *** markedly increased expression of p21 was observed at both m RNA and protein levels in the extract-treated adherent cells and *** addition,Ardisia gigantifolia extract significantly reduced the number of CD44-and/or ALDH-expressing gastric ***:The development of gastric CSC can be inhibited by the ethanol extract of Ardisia gigantifolia.

关键词： Ardisia gigantifolia Gastric cancer Cancer stem cell markers CD44 ALDH

A Neural-network-based Approach to Study the Energy-optimal Hovering Wing Kinematics of a Bionic Hawkmoth Model

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Journal of Bionic Engineering 2019年第5期16卷 904-915页

作者： Anh Tuan nguyen Ngoc Doan Tran thanh Trung Vu thanh Dong Pham Quoc Tru Vu Jae-Hung Han Faculty of Aerospace Engineering Le Quy Don Technical University236 Hoang Quoc VietVietnam Office of International Cooperation Le Quy Don Technical University236 Hoang Quoc VietVietnam Department ofAerospace Engineerings Korea Advanced Institute of Science and Technology Daejeon 34141Republic ofKorea

This paper presents the application of an artificial neural network to develop an approach to determine and study the energy-optimal wing kinematics of a hovering bionic hawkmoth model.A three-layered artificial neural network is used for the rapid prediction of the unsteady aerodynamic force acting on the wings and the required *** this artificial network is integrated into genetic and simplex algorithms,the running time of the optimization process is reduced *** validity of this new approach is confirmed in a comparison with a conventional method using an aerodynamic model based on an extended unsteady vortex-lattice method for a sinu soidal wing kinematics *** studying the obtained results,it is found that actual hawkmoths do not hover under an energy-optimal ***,by tilting the stroke plane and lowering the wing positions,they can compromise and expend some energy to enhance their maneuverability and the stability of their flight.

关键词： optimal hovering wing kinematics artificial neural network insect flight genetic algorithm unsteady vortex-lattice method bionics

Simulation of cohesive crack growth by a variable-node XFEM

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Frontiers of Structural and Civil Engineering 2020年第1期14卷 215-228页

作者： Weihua FANG Jiangfei WU Tiantang YU thanh-Tung nguyen Tinh Quoc BUI Nanjing Automation Institute of Water Conservancy and Hydrology Nanjing 210012China Department of Engineering Mechanics Hohai UniversityNanjing 211100China Laboratory of Solid Structures University of LuxembourgLuxembourg L-1359Luxembourg Institute for Research and Development Duy Tan UniversityDa Nang City 550000Vietnam Department of Civil and Environmental Engineering Tokyo Institute of TechnologyTokyo 152-8552Japan

A new computational approach that combines the extended finite element method associated with variable-node elements and cohesive zone model is *** using a new enriched technique based on sign function,the proposed model using 4-node quadrilateral elements can eliminate the blending element *** also allows modeling the equal stresses at both sides of the crack in the crack-tip as assumed in the cohesive model,and is able to simulate the arbitrary crack-tip *** multiscale mesh technique associated with variable-node elements and the arc-length method further improve the efficiency of the developed *** performance and accuracy of the present approach are illustrated through numerical experiments considering both mode-I and mixed-mode fracture in concrete.

关键词： extended finite element method cohesive zone model sign function crack propagation

One-step hydrothermal synthesis of Sn-doped α-Fe_(2)O_(3) nanoparticles for enhanced photocatalytic degradation of Congo red

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Journal of Semiconductors 2022年第12期43卷 22-31页

作者： Van Nang Lam Thi Bich Vu Quang Dat Do Thi thanh Xuan Le Tien Dai nguyen T-thanh-Bao nguyen hoang Tung Do Thi Tu Oanh nguyen Department of Natural Sciences Hoa Lu UniversityNinh NhatNinh Binh CityViet Nam Institute of Theoretical and Applied Research Duy Tan UniversityHanoi 100000Viet Nam Faculty of Natural Sciences Duy Tan UniversityDa Nang 550000Vietnam Institute of Physics Vietnam Academy of Science and Technology10 Dao TanBa DinhHanoiVietnam Institute of Materials Science Vietnam Academy of Science and Technology18 Hoang Quoc VietCaugiayHanoiVietnam

We report on the synthesis of Sn-doped hematite nanoparticles(Sn-α-Fe_(2)O_(3) NPs)by the hydrothermal *** prepared Sn-α-Fe_(2)O_(3) NPs had a highly pure and well crystalline rhombohedral phase with an average particle size of 41.4 *** optical properties of as-synthesizedα-Fe_(2)O_(3) NPs show a higher bandgap energy(2.40-2.57 eV)than that of pure bulkα-Fe_(2)O_(3)(2.1 eV).By doping Sn intoα-Fe_(2)O_(3) NPs,the Sn-doped hematite was observed a redshift toward a long wavelength with in-creasing Sn concentration from 0%to 4.0%.The photocatalytic activity of Sn-dopedα-Fe_(2)O_(3) NPs was evaluated by Congo red(CR)dye *** degradation efficiency of CR dye using Sn-α-Fe_(2)O_(3) NPs catalyst is higher than that of pureα-Fe_(2)O_(3) *** highest degradation efficiency of CR dye was 97.8%using 2.5%Sn-dopedα-Fe_(2)O_(3) NPs catalyst under visible-light *** results suggest that the synthesized Sn-dopedα-Fe_(2)O_(3) nanoparticles might be a suitable approach to develop a photocatalytic degradation of toxic inorganic dye in wastewater.

关键词： α-Fe_(2)O_(3)nanoparticles Sn Congo red photocatalytic properties photodegradation

Moving Least Squares Interpolation Based A-Posteriori Error Technique in Finite Element Elastic Analysis

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Computer Modeling in Engineering & Sciences 2021年第10期129卷 167-189页

作者： Mohd Ahmed Devender Singh Saeed Al Qadhi nguyen Viet thanh Civil Engineering Department College of EngineeringKing Khalid UniversityAbha61421Saudi Arabia Ministry of Information Soochna BhavanCGO ComplexDelhi110003India Urban Transport&Coastal Engineering Department University of Transport and CommunicationsHanoi100000Vietnam

The performance of a-posteriori error methodology based on moving least squares(MLS)interpolation is explored in this paper by varying the finite element error recovery parameters,namely recovery points and field variable derivatives *** MLS interpolation based recovery technique uses the weighted least squares method on top of the finite element method’s field variable derivatives solution to build a continuous field variable derivatives *** boundary of the node support(mesh free patch of influenced nodes within a determined distance)is taken as circular,i.e.,circular support domain constructed using radial weights is *** field variable derivatives(stress and strains)are recovered at two kinds of points in the support domain,i.e.,Gauss points(super-convergent stress locations)and nodal *** errors are computed as the difference between the stress from the finite element results and projected stress from the post-processed energy norm at both elemental and global *** benchmark numerical tests using quadrilateral and triangular meshes measure the finite element errors in strain and stress *** numerical examples showed the support domain-based recovery technique’s capabilities for effective and efficient error estimation in the finite element analysis of elastic *** MLS interpolation based recovery technique performs better for stress extraction at Gauss points with the quadrilateral discretization of the problem *** is also shown that the behavior of the MLS interpolation based a-posteriori error technique in stress extraction is comparable to classical Zienkiewicz-Zhu(ZZ)a-posteriori error technique.

关键词： Recovery points field variable derivatives effectivity error recovery support domain error convergence

A Correlation Coefficient Approach for Evaluation of Stiffness Degradation of Beams Under Moving Load

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Computers, Materials & Continua 2019年第7期61卷 27-53页

作者： thanh Q.nguyen Thao T.D.nguyen H.nguyen-Xuan Nhi K.Ngo Laboratory of Applied Mechanics(LAM) Ho Chi Minh City University of TechnologyHo Chi Minh City740030Vietnam Saigon Hi-Tech Park Training Center Ho Chi Minh City715650Vietnam Ho Chi Minh City Department of Transportation and Communication Ho Chi Minh City710100Vietnam CIRTECH Institute Ho Chi Minh City University of Technology(HUTECH)Ho Chi Minh City717349Vietnam Department of Physical Therapy Graduate Institute of Rehabilitation ScienceChina Medical UniversityTaichung40402Taiwan

This paper presents a new approach using correlation and cross-correlation coefficients to evaluate the stiffness degradation of beams under moving *** theoretical study of identifying defects by vibration methods showed that the traditional methods derived from the vibration measurement data have not met the needs of the actual *** show that the correlation coefficients allow us to evaluate the degree and the effectiveness of the defects on *** the same time,the cross-correlation model is the basis for determining the relative position of *** results of this study are experimentally conducted to confirm the relationship between the correlation coefficients and the existence of the *** particular,the manuscript shows that the sensitivity of the correlation coefficients and cross-correlation is much higher than the parameters such as changes in stiffness(EJ)and natural frequency values(Δf).This study suggests using the above parameters to evaluate the stiffness degradation of beams by vibration measurement data in practice.

关键词： Correlation coefficient cross-correlation vibration signal vibration amplitude frequency

Effective plant discrimination based on the combination of local binary pattern operators and multiclass support vector machine methods

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Information Processing in Agriculture 2019年第1期6卷 116-131页

作者： Vi nguyen thanh Le Beniamin Apopei Kamal Alameh Edith Cowan University–Electron Science Research Institute Australia

Accurate crop and weed discrimination plays a critical role in addressing the challenges of weed management in *** use of herbicides is currently the most common approach to weed ***,herbicide resistant plants have long been recognised as a major concern due to the excessive use of *** weed detection techniques can reduce the cost of weed management and improve crop quality and yield.A computationally efficient and robust plant classification algorithm is developed and applied to the classification of three crops:Brassica napus(canola),Zea mays(maize/corn),and *** developed algorithm is based on the combination of Local Binary Pattern(LBP)operators,for the extraction of crop leaf textural features and Support vector machine(SVM)method,for multiclass plant *** paper presents the first investigation of the accuracy of the combined LBP algorithms,trained using a large dataset of canola,radish and barley leaf images captured by a testing facility under simulated field *** dataset has four subclasses,background,canola,corn,and radish,with 24,000 images used for training and 6000 images,for *** dataset is referred herein as "bccr-segset"and published *** each subclass,plant images are collected at four crop growth ***,the algorithm demonstrates plant classification accuracy as high as 91.85%,for the four classes.

关键词： Plant discrimination Classification LBP PCA and SVM

Fuzzy MCDM for Improving the Performance of Agricultural Supply Chain

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Computers, Materials & Continua 2022年第11期73卷 4003-4015页

作者： Le Thi Diem My Chia-Nan Wang nguyen Van thanh Department of Industrial Engineering and Management National Kaohsiung University of Science and TechnologyKaohsiung CityTaiwan Faculty of Commerce Van Lang UniversityHo Chi Minh CityVietnam

Fertilizer industry in Vietnam and globally have entered the saturation *** the growth rate slowing down,this poses challenges for the development impetus of the fertilizer industry in the next *** fact,over the past few decades,Vietnam’s crop industry has abused excessive investment in chemical fertilizers,with organic fertilizers are rarely used or not at all,limiting crop productivity,increasing pests and *** develop sustainable agriculture,Vietnam’s crop industry must limit the use of chemical fertilizers,increase the use of environmentally friendly organic and natural mineral fertilizers to produce clean agricultural products which is ***,it is necessary to consider and choose the right supplier to ensure the goal of sustainable *** Fuzzy Analytic Hierarchy Process(SF-AHP),and the combinative distance-based assessment(CODAS)are new Multicriteria Decision Making(MCDM)method which can be used to solve supplier selection *** paper uses an effective solution based on a combined the concept of triple bottom line(TBL),SF-AHP and CODAS approach to help agriculture companies that need to select the best fertilizer *** research can support supply chain managers to achieve supply chain systems that reduce not only sourcing costs,but also develop sustainable agriculture.

关键词： Fuzzy theory MCDM model fertilizer agricultural supply chain optimization

Fuzzy Multi-Criteria Decision Making for Solar Power Plant Location Selection

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Computers, Materials & Continua 2022年第9期72卷 4853-4865页

作者： Thai hoang Tuyet Nhi Chia-Nan Wang nguyen Van thanh Department of Industrial Engineering National Kaohsiung University of Science and Technology80778Taiwan Faculty of Commerce Van Lang UniversityHo Chi Minh CityVietnam

Vietnam is one of Southeast Asian countries with a rapid GDP growth rate,ranging from 6.5%to 7%annually,leading to an average increase in energy demand of 11%per *** demand creates many new opportunities in the energy industry,especially renewable energy,to ensure sustainable development in the future for the country with applications of solar energy growing at the present,and other opportunities to expand in the *** Vietnam,thanks to favorable weather,climate,terrain characteristics and many preferential support policies,there are many great opportunities in the field of solar energy exploitation and *** selection is an important problem in all renewable energy ***,the author proposed a fuzzy Multi-criteria Decision-Making Model(MCDM)model for solar power plant location selection in this study,and as a result,location 5 is the optimal *** contribution of this study is to propose a MCDM for solar power plant location selection in Vietnam under fuzzy environmental conditions.

关键词： Solar power multi-decision topsis fanp fuzzy theory