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A crate of Pandora:do amyloids from bacteria promote Alzheimer’s disease?

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Neural Regeneration Research 2021年第5期16卷 988-989页

作者： Vu thu thuy nguyen Kristina Endres Department of Psychiatry and Psychotherapy University Medical Center Johannes Gutenberg-University MainzMainzGermany

Incidence for microbes as drivers of Alzheimer’s disease(AD)pathology:AD is the predominant neurodegenerative disease within the *** 50 million patients suffer from dementia currently world-wide and an estimated tripling of numbers within the next 30 years is *** one to maximally five percent of all cases of AD are based on mutations in the amyloid precursor protein(APP)gene or within the presenilin genes(PS1/PS2)and therefore are called familial(FAD).The majority of cases has to be designated as sporadic,which frankly only means that the origin of these cases is still enigmatic.

关键词： amyloid Alzheimer pathology

New Results on H_(∞) Control for Nonlinear Conformable Fractional Order Systems

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Journal of Systems Science & Complexity 2021年第1期34卷 140-156页

作者： MAI Viet thuan nguyen Thi Huyen thu nguyen Huu Sau nguyen Thi Thanh Huyen Department for Management of Science and Technology Development Ton Duc Thang UniversityHo Chi Minh CityVietnam Faculty of Mathematics and Statistics Ton Duc Thang UniversityHo Chi Minh CityVietnam Faculty of General Science Hanoi University of Natural Resources and EnvironmentHanoiVietnam Faculty of Fundamental Science Hanoi University of IndustryHa NoiVietnam Department of Mathematics and Informatics Thainguyen University of SciencesThainguyenVietnam

This paper deals with H_(∞) control problem for nonlinear conformable fractional order systems. The authors first derive new sufficient condition for exponential stability of nonlinear conformable fractional order systems based on Lyapunov-like function method for conformable fractional order systems and linear matrix inequalities(LMIs) approach. Then, by introducing a new concepts of H_(∞) control problem for nonlinear conformable fractional order systems, the authors study H_(∞) performance analysis and H_(∞) state feedback controller design problems for the considered systems. In terms of LMIs, a sufficient condition is proposed to ensure the nonlinear conformable fractional order systems are not only exponentially stable, but also satisfy H_(∞) performance γ. An explicit expression for state feedback controllers is also designed to make the closed-loop system is exponentially stable with H_∞performance γ. Finally, numerical examples are given to illustrate the validity and effectiveness of the proposed results.

关键词： Conformable fractional-order H_(∞)control problems H_(∞)performance analysis linear matrix inequalities nonlinear systems

Automatic Identification Fingerprint Based on Machine Learning Method

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Journal of the Operations Research Society of China 2022年第4期10卷 849-860页

作者： Long The nguyen Huong thu nguyen Alexander Diomidovich Afanasiev Tao Van nguyen Laboratory of Artificial Intelligence and Machine Learning Institute of Information Technology and Data ScienceIrkutsk National Research Technical UniversityIrkutskRussia Baikal School of BRICS Irkutsk National Research Technical UniversityIrkutskRussia University of Information and Communication Technology Thai Nguyen UniversityThai NguyenViet Nam

The fingerprint identification technology has been developed and applied effectively to security systems in financial transactions,personal information security,national security,and other *** this paper,we proposed the development of a fingerprint identification system based on image processing methods that clarify fingerprint contours,using machine learning methods to increase processing speed and increase the accuracy of the fingerprint identification *** identification system consists of the following main steps:improving image quality and image segmentation to identify the fingerprint area,extracting features,and matching the *** accuracy of the system reached 97.75%on the mixed high-and low-quality fingerprint database.

关键词： Fingerprint identification Feature extraction Image segmentation Wavelet transform Neural network algorithm Machine learning

Ethyl acetate extract of Smilax glabra Roxb roots and its major active compound astilbin promote osteoblastogenesis in vitro by upregulating bone cell differentiation-associated genes

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Asian Pacific Journal of Tropical Biomedicine 2021年第12期11卷 553-560页

作者： Huyen T.T.nguyen Minh T.H.nguyen thu X.nguyen Quan M.Pham ha X.nguyen Phuong T.M.nguyen University of Science and Technology of hanoi Vietnam Academy of Science and TechnologyHanoiVietnam Institute of Biotechnology Vietnam Academy of Science and TechnologyHanoiVietnam Institute of Natural Products Chemistry Vietnam Academy of Science and TechnologyHanoiVietnam Graduate University of Science and Technology Vietnam Academy of Science and TechnologyHanoiVietnam

Objective:To investigate the osteoblastogenic activity of the ethyl acetate(EtOAc)extract of Smilax glabra Roxb roots and its major active compound ***:Astilbin was isolated from EtOAc extract using silica gel chromatography combined with fraction *** structure of astilbin was determined by analysis of the spectroscopic data in comparison with the *** method was used to detect the *** phosphatase(ALP)activity was determined by the spectrophotometric method at 405 nm using p-nitrophenyl phosphate as a *** deposition was stained with alizarin red-S,distained with cetylpyridium chloride,and quantified at 562 *** silico model for astilbin-ALP interaction was analyzed using AutoDock *** changes in expression of osteoblast differentiation related genes were determined using quantitative real-time ***:Both the EtOAc extract and astilbin had no toxicity toward osteoblast MC3T3-E1 cells at 5.0,10,25,and 50μg/*** 25μg/mL,they enhanced ALP activity and mineralization of osteoblasts up to 30%and 55%for the EtOAc extract and 22%and 41%for astilbin,*** docking analysis of astilbin-ALP interaction revealed Arg167,Asp320,His324,and His437 were key residues participating in hydrophobic interaction;meanwhile,His434 and Thr436 residues were involved in hydrogen bond formation in the active site of human tissue-nonspecific ***,the expression level of genes opn,col1,osx,and runx2 were up-regulated in astilbin treated samples with the fold changes as 2.2;3.7;4.1;2.3,respectively at 10μg/mL(P<0.05).Conclusions:The EtOAc extract and its major compound astilbin exhibit osteoblastogenic activity by up-regulating important markers for bone cell *** could be a new and promising osteogenic agent with dual actions for therapeutic applications.

关键词： Smilax glabra Roxb Astilbin Cytotoxicity Osteogenesis Osteoblast Ethyl acetate extract

Polygonatum kingianum rhizome extract alleviates collagen antibody-induced arthritis by modulating proinflammatory cytokine production in mice

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Asian Pacific Journal of Tropical Biomedicine 2020年第11期10卷 490-495页

作者： Huyen Do Thi Thanh Phuong Ngo Thi Hien nguyen Thi thu Nga nguyen Thi Hung Le Ngoc Thao DoThi ha Le Minh Graduate University of Science and Technology Vietnam Academy of Science and Technology18 Hoang Quoc VietNghia DoCau GiayHanoiVietnam Institute of Natural Products Chemistry Vietnam Academy of Science and Technology18 Hoang Quoc VietNghia DoCau GiayHanoiVietnam hanoi Open University101 nguyen Hien str Hai Ba Trung Dist.HanoiVietnam Laboratory of Bioassay Institute of BiotechnologyVietnam Academy of Science and Technology18 Hoang Quoc VietNghia DoCau GiayHanoiVietnam Chemistry Lab Project Center for Research and Technology transferVietnam Academy of Science and Technology18 Hoang Quoc VietNghia DoCau GiayHanoiVietnam

Objective: To evaluate the anti-arthritic effects of Polygonatum kingianum rhizome extract using both in vitro and in vivo ***: Lipopolysaccharide-induced RAW 264.7 macrophages were treated with an ethanol extract of Polygonatum kingianum rhizomes at different concentrations to determine nitric oxide and prostaglandin E2(PGE2) production. For in vivo study, Polygonatum kingianum ethanol extract was further investigated for its antiinflammatory effect in a mouse model with collagen antibodyinduced arthritis. Phytochemical study of Polygonatum kingianum ethanol extract was also ***: Saponins(142 mg/g total yield) was the main component in the Polygonatum kingianum ethanol extract. 5α,8α-ergosterol peroxide,(E,E)-9-oxooctadeca-10,12-dienoic acid and 3-(2?-hydroxy-4?-methoxy-benzyl)-5,7-dihydroxy-8-methyl-chroman-4-one were isolated from the extract. Polygonatum kingianum ethanol extract exhibited potential anti-inflammatory effects by inhibiting nitric oxide and PGE2 production in RAW 264.7 cells in a dosedependent manner. The level of arthritis in mice with collagen antibody-induced arthritis was significantly reduced(Phanol extract, particularly at a dose of 1 000 mg/kg body weight. Besides, the extract demonstrated the regulatory effects on serum tumor necrosis factoralpha, interleukin-6, and interleukin-10 in treated ***: Polygonatum kingianum ethanol extract has beneficial effects on inflammatory cytokine regulation and PGE2 inhibition in an experimental mouse model with collagen antibody-induced arthritis. The phytochemical screening reveals that the saponin, as the main component, and sterols(daucosterol and 5α,8α-ergosterol peroxide) from Polygonatum kingianum ethanol extract may contribute to its promising in vitro and in vivo anti-inflammatory activities.

关键词： inflammatory cytokine PGE2

EP Aquarii:A New Picture of the Circumstellar Envelope

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Research in Astronomy and Astrophysics 2024年第3期24卷 83-105页

作者： Pham T.Nhung Do T.Hoai Pierre Darriulat Pham Tuan-Anh Pham N.Diep nguyen B.Ngoc Tran T.Thai Department of Astrophysics Vietnam National Space CenterVietnam Academy of Science and Technology18Hoang Quoc VietNghia DoCau GiayHa Noivietnam

New analyses of earlier ALMA observations of oxygen-rich AGB star EP Aquarii are presented,which complete a previously published analysis and offer a different interpretation of the morpho-kinematics of the circumstellar *** birth of the equatorial density enhancement(EDE)is shown to occur very close to the star where evidence for rotation has been *** to the star and where outflows have been observed:their interaction with the gas of the nascent EDE is seen to play an important role in the development of the wind and the evolution of its radial velocity from 8 to 10 km s^(-1) on the polar symmetry axis to~2 km s^(-1) at the *** implies complex morpho-kinematics:making reliable interpretations with reasonable confidence is *** particular,it questions an earlier interpretation implying the presence of a white dwarf companion orbiting the star at an angular distance of -0″4 from its *** proposes instead an interpretation in terms of a standard mass ejection associated with a shock wave leaving a void of emission in its *** Doppler velocity wings are seen to consist of two components,the upper velocity end of the global wind,reaching above±12 km s^(-1),and an effective line broadening,confined within 200 mas from the center of the star,reaching above±20 km s^(-1) and interpreted as caused by the pattern of shock waves resulting from the interaction between stellar pulsation and convective cell partition.

关键词： stars AGB and post-AGB-(stars) circumstellar matter-radio lines stars

Integrating the valence theory and the norm activation theory to understand consumers’ e-waste recycling intention

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Chinese Journal of Population,Resources and Environment 2023年第1期21卷 26-36页

作者： Hong Thi thu nguyen University of Science and Education The University of DanangLe Duan RoadDanang 550000Vietnam

Electrical and electronic waste(e-waste)is a growing challenge,matching the widespread boom in the use of information and communication *** to an alarming increasing amount of e-waste,a low rate of consumer engagement in ensuring the proper disposal of such materials intensifies the pressure on the exist‐ing e-waste *** deal with this thorny problem,it is of great interest to grasp consumers’disposal and re‐cycling behavioral ***,this study attempts to understand complementary perspectives around consumers’e-waste recycling intention based on the integration of the valence theory and the norm activation *** data mining models using classification and prediction-based algorithms,namely Chi squared automatic interaction detector(ChaID),Neural network,Discriminant analysis,and Quick,unbiased,efficient statistical tree(QUEST),were employed to analyze a set of the 398 data collected in *** re‐sults revealed that the social support value is by far the most critical predictor,followed by the utilitarian value,task difficulty,and monetary *** is also noteworthy that the awareness of consequences,education background,the ascription of responsibility,and age were also ranked as critical affecting *** lowest influential predictors found in this study were income and *** addition,a comparison was made in terms of the classification performance of the four utilized data mining *** on several evalua‐tion measurements(confusion matrix,accuracy,precision,recall,specificity,F-measure,ROC curve,and AUC),the aggregated results suggested that ChaID and Neural network performed the *** findings of this research are expected to assist policymakers and future researchers in updating all information surround‐ing consumer behavioral intention-related topics focusing on ***,the adoption of data min‐ing algorithms for prediction is another insight of this study,which may shed the light o

关键词： ChaID Discriminant analysis E-waste recycling intention Neural network Norm activation theory QUEST Sustainable development goals Valence theory

Impact of Temperature Variation on Performance of Carbon Nanotube Field-Effect Transistor-Based on Chaotic Oscillator:A Quantum Simulation Study

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Chinese Physics Letters 2015年第3期32卷 141-144页

作者： Van ha nguyen hanjung Song Department of Nanoscience and Engineering Center for Nano ManufacturingInje University

We evaluate the impact of temperature on the output behavior of a carbon nanotube field effect transistor （CNFET） based chaotic generator. The sources cause the variations in both current-voltage characteristics of the CNFET device and an overall chaotic circuit is pointed out. To verify the effect of temperature variation on the output dynamics of the chaotic circuit, a simulation is performed by employing the CNFET compact model of Wong et al. in HSPICE with a temperature range from -100℃ to 100℃. The obtained results with time series, frequency spectra, and bifurcation diagram from the simulation demonstrate that temperature plays a significant role in the output dynamics of the CNFET-based chaotic circuit. thus, temperature-related issues should be taken into account while designing a high-quality chaotic generator with high stability.

关键词： CN Impact of Temperature Variation on Performance of Carbon Nanotube Field-Effect Transistor-Based on Chaotic Oscillator:A Quantum Simulation Study HSPICE MOSFET

Carboxymethyl starch cross-linked by electron beam radiation in presence of acrylic acid sensitizer

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Nuclear Science and Techniques 2013年第B12期24卷 19-22页

作者： Doan Binh nguyen Thanh Duoc Pham Thi thu Hong R & D Center for Radiation Technology Vietnam Atomic Energy Institute 202A St. 11 Linh Xuan Ward Thu Duc District Ho Chi Minh City Vietnam

Carboxymethyl starch (CMS) can be cross-linked by electron beam radiation to form a biocompatible and environment-friendly hydrogel at a high absorbed dose and a condensed CMS concentration. Acrylic acid (AAc) can be used as a sensitizer in order to reduce the absorbed doses to an acceptable certain level. At an absorbed dose of 3-4 kGy, the gel content of crosslinked CMS can be obtained about 50% with 5% (w/w) AAc concentration used. The compressive strength of CMS samples increased with increasing their cross-linked densities due to raising absorbed doses. The swelling ratio of cross-linked CMS was also attainable at a maximum of 50 times in the distilled water. The enzymatic degradation of cross-linked CMS was carried out in acetate buffer pH 4.6 with 0.1% α-amylase enzymatic solution incubated at 40°C for 6 h. The crosslinked CMS samples were degraded slower than uncrosslinked CMS ones. The results indicated that the highly cross-linked CMS was almost fully degradable when the enzymatic hydrolysis was performed during 6 h. The FT IR spectra of cross-linked CMS in the presence of AAc were examined to observe the carboxyl group of AAc in the structure of cross-linked CMS. The hydrophilic of cross-linked CMS surface was determined by a contact-angle analysis. © 2013, Science Press. All rights reserved.

关键词：交联密度羧甲基淀粉电子束辐射丙烯酸敏化剂 FT-IR光谱吸收剂量 CMS