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Comparative mammalian cell cytotoxicity of wastewater with elevated bromide and iodide after chlorination,chloramination, or ozonation

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Journal of Environmental Sciences 2017年第8期29卷 296-301页

作者： Shengkun Dong thanh H.nguyen Michael J.Plewa Department of Civil and Environmental Enoineering University of Illinois at Urbana-Champaign Urbana IL 61801 USA Department of Crop Sciences University of Illinois at Urbana-Champaign Urbana IL 61801 USA Safe Global Water Institute Uniuersity of Illinois at Urbana-Champaign Urbana IL 61801 USA

Recycling wastewater is becoming more common as communities around the world try to better control their water resources against an increased frequency of either prolonged droughts or intense flooding. For communities in coastal areas, wastewaters may contain elevated levels of bromide（Br^-） and iodide（I^-） from seawater intrusion or high mineral content of source waters. Disinfection of such wastewater is mandatory to prevent the spread of pathogens, however little is known about the toxicity of wastewater after disinfection in the presence of Br^-and I^-. In this study we compared the induction of chronic cytotoxicity in mammalian cells in samples of municipal secondary wastewater effluent amended with elevated levels of Br^-/I^-after disinfection by chlorine, chloramines or ozone to identify which disinfection process generated wastewater with the lowest level of adverse biological response. Chlorination increased mammalian cell cytotoxicity by 5times as compared to non-disinfected controls. Chloramination produced disinfected wastewater that expressed 6.3 times more cytotoxicity than the non-disinfected controls and was 1.3 times more cytotoxic than the chlorinated samples. Ozonation produced wastewater with cytotoxicity comparable to the non-disinfected controls and was at least 4times less cytotoxic than the chlorine disinfected wastewaters. These results indicate that compared to chlorination and chloramination, ozonation of wastewater with high Br^-/Ilevels yielded the lowest mammalian cell cytotoxicity, suggesting its potential as a more favorable method to disinfect wastewater with minimizing the biological toxicity in mind.

关键词： Cytotoxicity Ozonation Chlorination Chloramination Wastewater Bromide Iodide Disinfection

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Engine performance and combustion characteristics of a direct injection compression ignition engine fueled waste cooking oil synthetic diesel

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International Journal of Coal Science & Technology 2020年第3期7卷 560-570页

作者： thanh Viet nguyen Khanh Duc nguyen Nang Xuan Ho Vinh Duy nguyen Department of Internal Combustion Engine School of Transportation EngineeringHanoi University of Science and TechnologyHanoiViet Nam Faculty of Vehicle and Energy Engineering Phenikaa UniversityYen NghiaHa-Dong DistrictHanoiViet Nam

Biodiesels produced from various feedstocks have been considered as alternative fuels used in internal combustion engines without major *** research focuses on producing biodiesel from waste cooking oil(WCOSD)by the catalytic cracking method using MgO as the catalyst and comparing the engine operating characteristics of the test engine when using WCOSD and traditional diesel(CD)as test *** a result,the brake power of the test engine fueled WCOSD,and traditional diesel is ***,the engine fuel consumption in the case of using WCOSD is slight increases in some operating ***,the nitrogen oxides emissions of the test engine fueled WCOSD are higher than those of CD at all tested *** trend is opposite for hydrocarbon emission as the HC emission of the engine fueled by WCOSD reduces 26.3%on *** smoke emission of the test engine in case of using WCOSD is lower 17%on average than that of ***,the carbon monoxide emissions are lower at the low and medium loads and higher at the full *** results show that the new biodiesel has the same characteristics as those of commercial biodiesel and can be used as fuel for diesel engines.

关键词： Feedstock Waste cooking oil Engine characteristics Exhaust missions Ignition timing Fuel consumption

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Minimizing Warpage for Macro-Size Fused Deposition Modeling Parts

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Computers, Materials & Continua 2021年第9期68卷 2913-2923页

作者： thanh Thuong Huynh Tien V.T.nguyen Quoc Manh nguyen Trieu Khoa nguyen Department of Mechanical Engineering Can Tho UniversityCampus IICan ThoVietnam Faculty of Mechanical Technology Industrial University of Ho Chi Minh CityHo Chi Minh70000Vietnam Mechanical Engineering Department National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan Faculty of Mechanical Engineering Hung Yen University of Technology and EducationHung Yen16000Vietnam

In this study,we investigated warpage and corner lifting minimization for three-dimensional printed parts generated by macro-size fused deposition modeling(FDM).First,the reasons for warpage were theoretically *** approach revealed that the thermal deformation and differential volumetric shrinkage of the extruded molten plastic resulted in warpage of FDM *** addition,low adhesion between the deposited model and the heated or non-heated printing bed may intensify warpage *** a next step,initial small-size and medium-size models were used to identify parameters to manage and minimize warpage in a way that would reduce material consumption and running ***,a macro-size model was built to experimentally investigate and verify the technical solutions to minimize the warpage of FDM *** conclusion,an improved part with reduced warpage was efficiently produced after detailed consideration of thermal effects and adhesion *** exists to widen the application scope of FDM technology in manufacturing for processes like thermoforming that involve mold core fabrication with *** technology,which has applications not only in mechanical engineering but also in related engineering fields,is convenient and could readily be applied to practical manufacturing industries.

关键词： Fused deposition modeling corner lifting volumetric shrinkage thermal deformation acrylonitrile butadiene styrene filament

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Satellite-based monitoring of contrasting characteristics of suspended sediment discharged from the Red and the Ma river systems along the northern coast of Vietnam

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International Journal of Sediment Research 2019年第3期34卷 191-204页

作者： Yoshimitsu Tajima Kavinda Gunasekara Hung thanh nguyen Department of Civil Engineering Graduate School of Engineering The University of Tokyo Geo-Informatics Center Asian Institute of Technology Key laboratory of River and Coastal Engineering Vietnam Academy of Water Resources

The northern coast of Vietnam has accumulated a significant amount of sediment discharged from the multiple distributaries of rivers such as the Red River and Ma River. While recent decreases of the sediment supply appears to have a significant impact on coastal erosion, the complex network of these distributaries makes it difficult to determine the overall spatiotemporal characteristics of sediment discharges and related topographic changes. The goal of the current study is to develop a satellite-based monitoring system for observation of turbidity discharged from the multiple rivers and to investigate the applicability of the developed monitoring system through a case study on the northern coast of Vietnam. Based on the in-situ observed data, a formula was determined for estimation of the surface water turbidity as a function of the red band reflectance of Moderate Resolution Imaging Spectro-radiometer(MODIS) images. The formula was then combined with a newly determined threshold for cloud-masking to obtain maps of the nearshore turbidity patterns. These maps capture the spatiotemporal water surface turbidity along the entire coast of the Red River Delta and the coast around the Ma River mouth over the past sixteen years with frequency of twice a day. Finally, long-term trends of the turbidity patterns from multiple rivers were compared with the in-situ observation data and it was found that the Red River and the Ma River showed clearly contrasting characteristics, which reasonably explain the recent coastal shoreline changes and characteristics of sediment sampled along the coast.

关键词： Turbidity River mouth Coastal erosion MODIS

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Estimation of Land Use Changes in Tan Rai Bauxite Mine by Multi-Variants Change Vector Analysis (MCVA) on Multi-Temporal Remote Sensing Data

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Journal of Geoscience and Environment Protection 2020年第3期8卷 70-84页

作者： nguyen thanh Hoan Hoa Thuy Quynh Le Minh Hang nguyen Manh Ha Hoang thi huyen Ngoc Dang Xuan Phong Institute of Geography Vietnam Academy of Science and Technology Hanoi Vietnam Graduate University of Science and Technology Vietnam Academy of Science and Technology Hanoi Vietnam Le Quy Don Technical University Hanoi Vietnam

The Tan Rai Bauxite Project, which exploits a large bauxite mine in Lam Dong province, Vietnam has been in operation since 2012. In addition to the economic efficiency of the project, bauxite mining and processing uses a large area arable land and affect the regional environment. Remote sensing technology is increasingly widely used in many purposes in monitoring the changes of environment and resources, including land use change with high accuracy, giving managers more information to monitor the exploitation and use process of land resource. this study used a Change Vector Analysis (CVA) method of analysis on various remote sensing data sources to monitor the process of land exploitation and restoration of the Tan Rai Bauxite project. High-resolution remote sensing images were used as diverse as SPOT-5, VNREDSat-1, Google Earth from 2013 to 2019 to demonstrate the ability of the MCVA method to combine many other types of remote sensing images together. The results of fluctuation analysis were validated by 200 random points in the study area, and the accuracy of result is more than 90%. The results of land use change statistics were also compared with the annual data of Tan Rai Bauxite Factory. From this study, it can be concluded that the MCVA analysis method can quickly detect land use change areas and can combine many different image sources with a high accuracy. In addition, it also provides statistics of mining areas and restored areas, thereby assisting managers in monitoring the operation of the mine.

关键词： Bauxite Tan Rai MCVA Land Use Change Monitoring Multi-Sensors

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Clinical outcomes of patients with chronic hepatitis C after generic direct-acting antiviral treatments in Vietnam: A retrospective analysis

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Asian Pacific Journal of Tropical Medicine 2020年第11期13卷 487-493页

作者： Huong TT Vu Azumi Ishizaki Quynh T nguyen huyen N nguyen Hoi T Le Kinh V nguyen Hiroshi Ichimura National Hospital for Tropical Disease HanoiVietnam Department of Viral Infection and International Health Graduate School of Medical SciencesKanazawa UniversityJapan

Objective:To evaluate the outcomes of generic direct-acting antiviral treatments for chronic hepatitis C in ***:The medical records of 522 patients(median 45 years;Female,25.3%)with chronic hepatitis C treated at a tertiary hospital in northern Vietnam in 2016 were retrospectively ***:Female patients were significantly older than male patients(median 52,IQR 41-59 vs.43 years,IQR:39-55;P<0.001).Among 522 patients,49.4%were infected with hepatitis C virus(HCV)genotype 6,followed by 1 a(19.0%),1 b(13.0%),and 3(5.9%).Coinfection with hepatitis B virus or human immunodeficiency virus was noted in 5.8%and 3.1%of patients,*** were treated with ledipasvir/sofosbuvir with or without ribavirin(70.9%),sofosbuvir/pegylated-interferon+ribavirin(13.2%),daclatasvir/sofosbuvir with or without ribavirin(12.5%),or sofosbuvir/ribavirin(3.4%),and 96.4%(n=503)completed the direct-acting antiviral *** patient discontinued treatment due to adverse event(s).A sustained virologic response 12 weeks after the end of the treatment(SVR12)was evaluated in 62.6%of *** sustained virologic response 12 weeks after the end of the treatment was 98.7%regardless of HCV genotypes or direct-acting antiviral *** severity of liver stiffness was significantly decreased from 10.2 to 6.3 kilopascals measured by transient elastography by the treatment(P<0.001).Among patients who completed the directacting antiviral treatment,17.7%returned for further follow-ups after ***:In Vietnam,the current generic direct-acting antiviral treatment for chronic hepatitis C was effective regardless of HCV genotypes and direct-acting antiviral regimens with the attenuation of liver *** is feasible to implement direct-acting antiviral treatment to cure chronic hepatitis C patients at any liver fibrosis stages in Vietnam.

关键词： Vietnam Chronic hepatitis C Generic direct-acting antiviral Improvement of liver stiffness

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Stem cell-based therapy for human diseases

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Signal Transduction and Targeted Therapy 2022年第9期7卷 3242-3282页

作者： Duc M.Hoang Phuong T.Pham Trung Q.Bach Anh T.L.Ngo Quyen T.nguyen Trang T.K.Phan Giang H.nguyen Phuong T.T.Le Van T.Hoang Nicholas R.Forsyth Michael Heke Liem thanh nguyen Department of Research and Development Vinmec Research Institute of Stem Cell and Gene TechnologyVinmec Healthcare SystemHanoiVietnam Department of Cellular Therapy Vinmec High.Tech CenterVinmec Healthcare SsystemHanoiVietnam Institute for Science&Technology in Medicine Keele UniversityKeeleUK a Department of Biology Stanford UniversityStanfordCAUSA

Recent advancements in stem cell technology open a new door for patients suffering from diseases and disorders that have yet to be *** cell-based therapy,including human pluripotent stem cells(hPsCs)and multipotent mesenchymal stem cells(MSCs),has recently emerged as a key player in regenerative *** are defined as self-renewable cell types conferring the ability to differentiate into various cellular phenotypes of the human body,including three germ *** are multipotent progenitor cells possessing self-renewal ability(limited in vitro)and differentiation potential into mesenchymal lineages,according to the International Society for Cell and Gene Therapy(ISCT).this review provides an update on recent clinical applications using either hPSCs or MSCs derived from bone marrow(BM),adipose tissue(AT),or the umbilical cord(UC)for the treatment of human diseases,including neurological disorders,pulmonary dysfunctions,metabolic/endocrine-related diseases,reproductive disorders,skin burns,and cardiovascular ***,we discuss our own clinical trial experiences on targeted therapies using MsCs in a clinical setting,and we propose and discuss the MSC tissue origin concept and how MSC origin may contribute to the role of MSCs in downstream applications,with the ultimate objective of facilitating translational research in regenerative medicine into clinical *** mechanisms discussed here support the proposed hypothesis that BM-MSCs are potentially good candidates for brain and spinal cord injury treatment,AT-MSCs are potentially good candidates for reproductive disorder treatment and skin regeneration,and UC-MsCs are potentially good candidates for pulmonary disease and acute respiratory distress svndrometreatment.

关键词： diseases distress treatment

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Quality of Sleep among Pregnant Women

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International Journal of Clinical Medicine 2019年第1期10卷 16-25页

作者： nguyen thi thanh Huong nguyen thi Hoang Thuy Le thi Hai Yen Faculty of Nursing and Midwifery Hanoi Medical University Hanoi Vietnam Faculty of Nursing Hanoi Medical University Hanoi Vietnam National Hospital of Obstetrics and Gynecology Hanoi Vietnam

Objectives: The study aimed to describe the quality of sleep and explore factors especially Sleep Hygiene Practices associated with sleep quality among pregnant women. Study design: this is a cross-sectional study. Methods: 119 healthy pregnant women in two central hospitals in Vietnam were participated in this study. The Pittsburgh Sleep Quality Index (PSQI) was employed to evaluate sleep quality and the Modified Sleep Hygiene Practices was used to describe sleeping practices among pregnant women. Results: The results showed that while 58.8% pregnant women had quite good sleep quality, 41.2% of pregnant women had mild to moderate quality sleep disturbance. The quality of sleep was better in second trimester, but then getting worst in the third trimester. Multipara experienced worse sleep quality than nullipara. Poor sleep quality had a positive correlation with unhealthy Sleep Hygiene Practices including using an uncomfortable bed (p third trimester as they experience more change in hormone and physiology. Sleep Hygiene Practices should be emphasized in health education for pregnant women.

关键词： Quality of Sleep Pregnant Women

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Mechanism of back siltation in navigation channel in Dinh An Estuary, Vietnam

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Water Science and Engineering 2013年第2期6卷 178-188页

作者： Viet-thanh nguyen Jin-hai ZHENG Ji-sheng ZHANG State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering Hohai University College of Harbor Coastal and Offshore Engineering Hohai University Faculty of Civil Engineering University of Transport and Communications

The Dinh An Estuary is one of the Nine Dragon estuaries of the Mekong River. An international navigation channel was built in the estuary for vessels traveling from the South China Sea to the southwestern area of Vietnam and then to Phnom Penh, Cambodia. The morphological evolution of the navigation channel is complicated and unstable. The back siltation intensity in the navigation channel has largely increased and been concentrated in the curvature segments of the channel since 1980. In this study, based on simulation results and measured data, five key factors that influence the back siltation in the navigation channel were systematically analyzed. These factors included the increasing elevation gap between the channel and the nearby seabed, the disadvantageous hydrodynamic conditions, sediment transport, mixing of saltwater and freshwater, and wave effects in the navigation channel. It is shown that the back siltation to a large extent results from the low current velocity of the secondary ocean circulation, which often occurs in the curvature segments of the channel. Suspended sediment also settles in the channel due to the decrease of the current velocity and the sediment transport capacity when flow passes through the channel. The changes of hydrodynamic conditions are responsible for the majority of the severe siltation in the curvature segments of the navigation channel.

关键词： back siltation hydrodynamics navigation channel, sediment transport Dinh An Estuary

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Effect of Land Use Change on Runoff and Sediment Yield in Da River Basin of Hoa Binh province, Northwest Vietnam

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Journal of Mountain Science 2015年第4期12卷 1051-1064页

作者： NGO thanh Son nguyen Duy Binh Rajendra Prasad SHRESTHA Asian Institute of Technology Faculty of Land Resources Management Vietnam National University of Agriculture Faculty of Information Technology Vietnam National University of Agriculture

The objective of this study was to assess runoff discharge and sediment yield from Da River Basin in the Northwest of Vietnam using Soil and Water Assessment Tools(SWAT) *** SWAT model was calibrated and validated using the observed monthly stream flows and sediment yield at selected gauging *** results indicated that SWAT generally performs well in simulating runoff and sediment yield according to Nash-Sutcliffe efficiency(NSE), Observation's standard deviation ratio(RSR), and percent bias(PBIAS) *** runoff, the values of NSE, RSR, and PBIAS were 0.98,0.02, and 3.69 during calibration period and 0.99,0.01, and 1.56 during validation period, *** sediment yield, the efficiency was lower than the value of NSE, RSR, and PBIAS during calibration period were 0.81, 0.19, and-4.14 and 0.84, 0.16, and-2.56 during validation period, *** results of the study indicated that the vegetation status has a significant impact on runoff and sediment *** in land use type between 1995 and2005 from forest to field crop and urban strongly contributed to increasing the average annual runoff from 182.5 to 342.7 mm and sediment yield from101.3 to 148.1 ton-1 *** 2005 and 2010, adecrease of both runoff(from 342.7 to 167.6 mm) and sediment yield(from 148.1 to 74.0 ton-1 ha) was due to the expansion of forested area and application of soil conservation *** results of this study are important for developing soil and water conservation programs, extending future SWAT modelling studies and disseminating these results to other regions in Vietnam.

关键词：土地利用变化大流域西北部径流泥沙越南 SWAT模型森林覆盖面积

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