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Antibiotic usage in surgical sperm retrievals among IVF centers

Asian Journal of Andrology 2022年第6期24卷 633-638页

作者： Le Dang Khoa Ngo Dinh Trieu Vy nguyen minh tai loc Le Duc Thang Dang Tuan Anh nguyen Phuc Hieu Giang Huynh Nhu nguyen Dinh Tao Le Hoang David J Handelsman IVFTA Tam Anh General HospitalHo Chi Minh 700000Vietnam IVFTA Tam Anh General HospitalHa Noi 100000Vietnam IVF Center 16A Ha Dong HospitalHa Noi 100000Vietnam ANZAC Research Institute University of Sydney and Concord Repatriation General HospitalHospital RoadConcordNSW 2139Australia

Surgical sperm retrieval(SSR)is currently one of the most common procedures in in vitro fertilization(IVF).However,a gap between the guidelines and routine clinical practice regarding antibiotic use in sSR,which might lead to antibiotic resistance,is a challenging problem worldwide.A cross-sectional survey was conducted from May 1,2021,to July 15,2021,to investigate antibiotic usage by medical professionals when performing SSR in IVF centers in *** confidential questionnaire comprised 12 items,including characteristics of the study population,awareness of antimicrobial resistance,attitude toward prescribing antibiotics,and current practice of prescribing antibiotics when performing *** were completed by 30 of 45 registered IVF centers(66.7%).Among 67 physicians working at those centers,the age and work-experience years(mean±standard deviation[s.d.])were 38.6±6.6 years and 11.2±7.0 years,*** 60%of them held a degree in Obstetrics and Gynecology,and over four-fifths were *** respondents"often/very often/always"raised awareness of antimicrobial resistance to their patients(83.3%),but only half of them"often/occasionally"prescribed antibiotics to patients with SSR in cases where the prescription would be *** one-tenth of respondents followed the recommendation from the American Urological Association using"prophylaxis only"for SSR *** more invasive SSR,physicians tended to prescribe more complicated and sometimes inappropriate *** conclusion,antibiotic usage in SSR was not always appropriate among IVF *** studies may define specific recommendations for regimens,intervention strategies,and programs to promote appropriate antibiotic use for SSR patients among IVF specialists.

关键词： antibiotic usage in vitro fertilization prophylaxis surgical sperm retrieval treatment

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Adiponectin restores the obesity-induced impaired immunomodulatory function of mesenchymal stromal cells via glycolytic reprogramming

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Acta Pharmaceutica Sinica B 2024年第1期14卷 273-291页

作者： Duc-Vinh Pham Thi-Kem nguyen Bao-loc nguyen Jong-Oh Kim Jee-Heon Jeong Inho Choi Pil-Hoon Park Department of Pharmacology Hanoi University of PharmacyHanoi 100000Viet Nam College of Pharmacy Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Medical Biotechnology Yeungnam UniversityGyeongsan 38541Republic of Korea Research Institute of Cell Culture Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Precision Medicine School of MedicineSungkyunkwan UniversitySuwon 16419Republic of Korea

Obesity has been known to negatively modulate the life-span and immunosuppressive potential of mesenchymal stromal cells(MSC).However,it remains unclear what drives the compromised potency of obese *** this study,we examined the involvement of adiponectin,an adipose tissuederived hormone,in obesity-induced impaired therapeutic function of ***-induced obesity leads to a decrease in serum adiponectin,accompanied by impairment of survival and immunomodulatory effects of adipose-derived MSC(ADSC).Interestingly,priming with globular adiponectin(gAcrp)improved the immunomodulatory potential of obese *** effects were also observed in lean *** addition,gAcrp potentiated the therapeutic effectiveness of ADSC in a mouse model of DSS-induced ***,while obesity inhibited the glycolytic capacity of MSC,gAcrp treatment induced a metabolic shift toward glycolysis through activation of adiponectin receptor type 1/p38 MAPK/hypoxia inducible factor-1a *** findings suggest that activation of adiponectin signaling is a promising strategy for enhancing the therapeutic efficacy of MSC against immune-mediated disorders.

关键词： Adiponectin Adipose-derived stromal cells Colitis Glycolytic induction HIF1a Immunomodulation Mesenchymal stromal cells Obesity

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First Trimester Preeclampsia Screening and Prevention:Perspective in Chinese Mainland

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Maternal-Fetal Medicine 2024年第2期6卷 84-91页

作者： Jiao Liu Yunyu Chen Sin Ting tai Long nguyen-Hoang Kunping Li Jing Lin Xiaohong Lu Liona C.Poon Department of Obstetrics and Gynecology The Chinese University of Hong KongShatinHong Kong 999077China

Preeclampsia(PE),a multisystem disorder in pregnancy,is one of the leading causes of perinatal morbidity and mortality that poses financial and physical burdens *** PE with delivery attaining optimal screening *** rate of preterm PE can be reduced by 62%by using the FMF prediction model,followed by the administration of low-dose *** evidence has also demonstrated that metformin has the potential for preventing PE in patients at high-risk of the *** this article,we will summarize the existing literature on the different screening methods,different components of risk assessment,therapeutic interventions,and clinical implementation of the first trimester screening and prevention program for PE with specific considerations for Chinese mainland.

关键词： Preeclampsia Chinese population First trimester Screening Prevention

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The germline genetics of mild-to-moderate penetrance:An intriguing role of PRAME in multiple carcinogenesis

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Genes & Diseases 2024年第3期11卷 7-10页

作者： Diaddin Hamdan Van tai nguyen Justine Paris Christophe Leboeuf Morad El Bouchtaoui Marc Espie Anne Janin Geraldine Falgarone Melanie Di Benedetto Guithem Bousquet Universite de Paris Cite INSERMUMR_S942MASCOTParis F-75006France Hopital La Porte Verte Versailles F-78004France National Cancer Hospital Cancer Research and Clinical Trials CenterHaNoi100000VietNam AP-HP-Hopital Saint Louis Centre de Maladies du SeinParisF-75010France Universite Sorbonne Paris Nord Bobigny F-93000France AP-HP-Hopital Avicenne Unite de Medecine AmbulatoireBobigny F-93000France

Germline genetics of high penetrance such as BRCA genes,mutations might be sufficient for carcinogenesis,but this only explains fewer than 10%of *** assume that most cancers are the result of germline mutations of low to moderate penetrance,combined with acquired mutations due to external carcinogenic *** their accumulation over time,aging is associated with an increased risk of multiple cancer development in a given *** decades,germline genetics have been based on familial linkage studies enabling most high-penetrance genes to be *** recently,population-wide studies have led to the identification of considerable numbers of polymorphisms associated with cancer ***,most of them are of unknown functional value,thus limiting their translational application.

关键词： carcinogenesis BRCA linkage

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A Study on Optimizing the Double-Spine Type Flow Path Design for the Overhead Transportation System Using Tabu Search Algorithm

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Intelligent Automation & Soft Computing 2024年第2期39卷 255-279页

作者： nguyen Huu loc Khuu Thuy Duy Truong Quoc Dien Le Tran Thanh Cong Vu Hoa Binh Tran Tuong Quan Vo Department of Mechatronics Faculty of Mechanical EngineeringHo Chi Minh City University of Technology(HCMUT)Ho Chi Minh CityVietnam Bach Khoa Research Center for Manufacturing Engineering Ho Chi Minh City University of Technology(HCMUT)Ho Chi Minh CityVietnam VietnamNational University Ho Chiminh City Ho ChiMinh CityVietnam

Optimizing Flow Path Design(FPD)is a popular research area in transportation system design,but its application to Overhead Transportation Systems(OTSs)has been *** study focuses on optimizing a double-spine flow path design for OTSs with 10 stations by minimizing the total travel distance for both loaded and empty *** employ transportation methods,specifically the North-West Corner and Stepping-Stone methods,to determine empty vehicle travel ***,the Tabu Search(TS)algorithm is applied to branch the 10 stations into two main layout *** results obtained from our proposed method demonstrate a reduction in the objective function value compared to the initial feasible ***,we explore howchanges in the parameters of the TS algorithm affect the optimal *** validate the feasibility of our approach by comparing it with relevant literature and conducting additional tests on layouts with 20 and 30 stations.

关键词： Overhead transportation systems tabu search double-spine layout transportationmethod empty travel flow path design

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Novel Deletion in Exon 7 of Betaine Aldehyde Dehydrogenase 2(BADH2)

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Rice science 2023年第2期30卷 104-112,I0020-I0030页

作者： VAN Quoc Giang HUYNH Ky nguyen Chau Thanh Tung nguyen loc Hien nguyen van Manh nguyen Nhut Thanh VO Cong Thanh SWEE Keong Yeap College of Agriculture Can Tho UniversityCan Tho 92000Vietnam Department of Sciences and Technology of Long An Province Long An 850000Vietnam China-Association of Southeast Asian Nations College of Marine Sciences Xiamen University MalaysiaSepang 49000SelangorMalaysia

The fragrance of rice is one of the premium characteristics that breeders want to include in rice varieties due to the higher market value. Nucleotide deletions in exons 2(7 bp) and 7(8 bp) of Betaine Aldehyde Dehydrogenase 2(BADH2) are associated with fragrance in rice. In this study, a new 13 bp deletion in exon 7 of the BADH2 gene was discovered in the Nang Thom Cho Dao(NTCD) variety, and the mutation has been closely related to the genetic background of indica subspecies through the Bayesian phylogenetic approach and haplotype network analysis of the 3 000 Rice Genomes Project. In addition, a set of functional markers(EX07-13F, EX07-13RN, and EX07-13RM) identified the 13 bp deletion only within NTCD(no amplified band) compared with both non-aromatic and other aromatic rice varieties(110 bp band). The deletion of 13 bases instead of 8 bases in exon 7 of BADH2 caused a premature stop codon, which down-regulated the expression of the BADH2 transcript while associated with up-regulation of OsP5CS and the high amount of 2-acetyl-1-pyrroline. It is potential to use the deletion in exon 7 of the BADH2 gene as a novel marker for adulteration and breeding of fragrant rice varieties, particularly for NTCD.

关键词： novel deletion BADH2 fragrant rice functional marker

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A noncoding secret to stay young—protecting T_(reg)cells to keep the balance in the liver

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Science China(Life Sciences) 2023年第11期66卷 2694-2696页

作者： Hiep tai nguyen Pedro J.Batista Laboratory of Cell Biology Center for Cancer ResearchNational Cancer InstituteNational Institutes of HealthBethesda MD 20892 USA

The liver plays a crucial role in maintaining whole-body metabolic homeostasis and harbors a distinct immune environment(Robinson et al.,2016).However,during the aging process,the liver undergoes structural and functional changes that can disrupt the delicate balance between the immune system and liver *** age-related alterations can lead to increased susceptibility to metabolic diseases,including non-alcoholic fatty liver disease(NAFLD),and impairments in immune cell regulation and tissue repair(Albillos et al.,2022;Anstee et al.,2019).

关键词： al. alterations homeostasis

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Synthesis and characterization of core/shell structured nanophosphors CePO_4:Tb@LaPO_4 by solvothermal method

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Journal of Rare Earths 2011年第12期29卷 1147-1151页

作者： Dinh Xuan loc Tran Thi Kim Chi Tran Thu Huong nguyen Vu Tran Kim Anh Wieslaw Strek Le Quoc minh Institute of Materials Science Vietnam Academy of Science and Technology Institute of Low Temperature and Structure Research Polish Academy of Sciences(PAN) University of Engineering and Technology

Core/shell structured CePO4：Tb（Ⅲ）@LaPO4 and CePOa：Tb（Ⅲ） were successfully synthesized in tris（2-ethylhexyl） phosphate （TEHP） and diethylene glycol （DEG） solvents for comparison of the two techniques in open air and closed reaction vessel. Morphology and crystal structure of the core/shell nanophosphors were determined by using X-ray diffraction （XRD） and transmission electron microscopy （TEM）, which showed that nanophosphors had diameter of about 5-10 nm with the monoclinic monazite phase. The nanophosphors obtained by close vessel procedure showed smaller size, more homogeneity and pure crystallite. The luminescent measurements were done upon the different excitation wavelengths in ultraviolet region and at room temperatm＇e to elucidate the influences of the used solvents and the reaction temperatures. It was found that CePO4：Tb@LaPO4 preparedby the close vessel synthesis showed the intensity of green band of the transfer from 5D4 to 7F5 energy level, which was strongly increased, and the luminescent decay time was 3.2 ms, which was longer than that of naked CePO4：Tb phosphor.

关键词： solvothermal synthesis luminescence CePOn:Tb CePOa:Tb@LaPO4 rare earths

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Classifying Two Populations by Bayesian Method and Applications

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Communications in Mathematics and Statistics 2019年第2期7卷 141-161页

作者： tai Vovan loc Tranphuoc Ha Chengoc College of Science Can Tho UniversityCan Tho CityViet Nam Faculty of Mathematics and Statistics Ton Duc Thang UniversityHo Chi Minh CityViet Nam

This article proposes some related issues to classification problem by Bayesian method for two *** are relationships between Bayes error(BE)and other measures and the results for determining the *** addition,we propose three methods to find the prior probabilities that can make to reduce *** calculation of these methods can be performed conveniently and efficiently by the MATLAB *** new approaches are tested by the numerical examples including synthetic and benchmark data and applied in medicine and *** examples also show the advantages of the proposed methods in comparison with existing methods.

关键词： Bayes error Classification Measure Posterior Prior

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An Automatic Fuzzy Clustering Algorithm for Discrete Elements

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Journal of the Operations Research Society of China 2023年第2期11卷 309-325页

作者： tai Vovan Yen nguyenhoang Sang Danh College of Natural Science Can Tho UniversityCan Tho cityVietnam nguyen Trung Truc College Rach Gia cityVietnam

This research proposes a measure called cluster similar index(CSI)to evaluate the similarity of cluster for discrete *** CSI is used as a criterion to build the automatic fuzzy clustering *** algorithm can determine the suitable number of clusters,find the elements in each cluster,give the probability to belong to the clusters of each element,and evaluate the quality of the established clusters at the same *** proposed algorithm can perform quickly and effectively by the established MATLAB *** numerical examples illustrate the proposed algorithm and show the advantages in comparing with the existing ***,applying the proposed algorithm in the image recognition shows potentiality in the reality of this research.

关键词： Cluster analysis Distance Image Similar index

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