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Examination of n-T_(9) conditions required by N=50,82,126 waiting points in r-process

Communications in Theoretical Physics 2021年第10期73卷 147-157页

作者： nguyen Duy Ly nguyen Ngoc Duy nguyen kim uyen Vinh N T Pham Faculty of Fundamental Sciences Vanlang UniversityHo Chi Minh City 700000Vietnam Department of Physics Sungkyunkwan UniversitySuwon 16419Republic of Korea Department of Physics Ho Chi Minh City University of EducationHo Chi Minh City 700000Vietnam

We examined the conditions of neutron density(n) and temperature(T9) required for the N = 50, 82,and 126 isotopes to be waiting points(WP) in the r-process. The nuclear mass based on experimental data presented in the AME2020 database(AME and AME ± Δ) and that predicted using FRDM,WS4, DZ10, and KTUY models were employed in our estimations. We found that the conditions required by the N = 50 WP significantly overlap with those required by the N = 82 ones, except for the WS4 model. In addition, the upper(or lower) bounds of the n-T9 conditions based on the models are different from each other due to the deviations in the two-neutron separation *** standard deviations in the nuclear mass of 108 isotopes in the three N = 50, 82, and 126 groups are about rms = 0.192 and 0.434 Me V for the pairs of KTUY-AME and WS4-KTUY models,respectively. We found that these mass uncertainties result in a large discrepancy in the nn-T_(9) conditions, leading to significant differences in the conditions for simultaneously appearing all the three peaks in the r-process abundance. The newly updated FRDM and WS4 calculations can give the overall conditions for the appearance of all the peaks but vice versa for their old versions in a previous study. The change in the final r-process isotopic abundance due to the mass uncertainty is from a few factors to three orders of magnitude. Therefore, accurate nuclear masses of the r-process key nuclei, especially for 76 Fe,81Cu,127Rh,132Cd,192Dy, and 197Tm, are highly recommended to be measured in radioactive-ion beam facilities for a better understanding of the r-process evolution.

关键词： neutron capture r-process nuclear mass isotopic abundance precise mass measurement

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Prevalence and risk factors associated with long COVID symptoms in children and adolescents in a southern province of Vietnam

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Asian Pacific Journal of Tropical Medicine 2024年第3期17卷 119-128,I0001,I0002页

作者： Huynh Ngoc Linh nguyen The Tan Le Thi Minh Thu nguyen Tu Loan nguyen Thi To uyen Le Thanh Thao Trang Truong Thanh Nam Doan Hoang Phu Faculty of Medicine Ca Mau Medical CollegeCa Mau 98000Vietnam Ca Mau Obstetrics and Pediatrics Hospital Ca Mau 98000Vietnam Faculty of Basic Science and Public Health Dong Thap Medical CollegeDong Thap 81000Vietnam Graduate University of Sciences and Technology Vietnam Academy of Science and TechnologyHa Noi 10000Vietnam Community Public Health Research Program School of Public HealthWalailak UniversityNakhon Si Thammarat 80160Thailand Faculty Public Health Can Tho University of Medicine and PharmacyCan Tho City 94000Vietnam Doctoral Program in Health Sciences College of Graduate StudiesWalailak UniversityNakhon Si Thammarat 80160Thailand

Objective:To investigate the prevalence and risk factors associated with long COVID symptoms among children and adolescents who have recovered from ***:This study applied a cross-sectional approach within community settings in a southern province of Vietnam.A structured questionnaire featuring socio-demographic information and common long COVID symptoms was *** correlation coefficients assessed associations among pairs of long COVID ***,multivariable logistic regression models were performed to investigate the risk factors of long COVID in recovered COVID-19 children and ***:Among 422 participants,39.3%reported long COVID symptoms,with a prevalence of 45.2%(SD=0.5)in children and 22.2%(SD=0.4)in *** symptoms reported were cough 34.6%(SD=0.5),fatigue 20.6%(SD=0.4),shortness of breath 10.9%(SD=0.3),and lack of appetite 6.6%(SD=0.3).Concerning risk factors of long COVID,a higher risk was observed among demographic groups,including girls(OR 1.25,95%CI 1.15-1.37;P<0.001,reference:boys),children compared to adolescents(OR 1.24,95%CI 1.12-1.37;P<0.001),overweight individuals(OR 1.14,95%CI 1.02-1.27;P=0.018,reference:healthy weight),and participants without any COVID-19 vaccination(OR 1.36,95%CI 1.20-1.54;P<0.001),or have received only one single dose(OR 1.35,95%CI 1.10-1.64;P=0.004)compared to those who have received two ***,patients with a COVID-19 treatment duration exceeding two weeks also had a higher risk of long COVID(OR 1.32,95%CI 1.09-1.60;P=0.003)than those who recovered less than seven ***:The insights from this study provide crucial guidance for predicting the factors associated with the occurrence of long COVID in pediatric patients,contributing to strategic interventions aimed at mitigating the long COVID risks among children and adolescents in Vietnam.

关键词： Long COVID Prevalence Risk factors Children Adolescent Vietnam

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Discovering peptides and computational investigations of a multiepitope vaccine target Mycobacterium tuberculosis

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Synthetic and Systems Biotechnology 2024年第3期9卷 391-405页

作者： Truc Ly nguyen Heebal kim Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences Seoul National UniversitySeoul08826Republic of Korea Interdisciplinary Program in Bioinformatics Seoul National UniversitySeoul08826Republic of Korea eGnome Inc.Seoul05836Republic of Korea

Mycobacterium tuberculosis(MTB)is the causative agent of tuberculosis(TB),a prevalent airborne infectious *** the availability of the Bacille Calmette-Guerin vaccine,its global efficacy remains modest,and tuberculosis persists as a significant global public health *** this challenge and advancing towards the End MTB Strategy,we developed a multiepitope vaccine(MEV)based on immunoinformatics and compu-tational *** screening of MBT protein identified immune-dominant epitopes based on Major Histocompatibility Complex(MHC)allele binding,immunogenicity,antigenicity,allergenicity,toxicity,and cytokine *** epitopes were integrated into an MEV construct with adjuvant and linkers,forming a fully immunogenic vaccine *** analyses encompassed the evaluation of immunological and physicochemical properties,determination of tertiary structure,molecular docking with Toll-Like Receptors(TLR),molecular dynamics(MD)simulations for all atoms,and immune *** MEV comprises 534 amino acids,featuring 6 cytotoxic T lymphocyte,8 helper T lymphocyte,and 7 linear B lymphocyte epitopes,demonstrating high antigenicity and ***,molecular docking studies and triplicate MD simulations revealed enhanced interactions and stability of MEV with the TLR4 complex compared to *** addition,the immune simulation indicated the capacity to effectively induce elevated levels of an-tibodies and cytokines,emphasizing the vaccine’s robust immunogenic *** study presents a promising MEV against TB,exhibiting favorable immunological and physicochemical *** findings provide theoretical support for TB vaccine *** study aligns with the global initiative of the End MTB Strategy,emphasizing its potential impact on addressing persistent challenges in TB control.

关键词： Mycobacterium tuberculosis Tuberculosis Multiepitope vaccine Docking molecular Molecular dynamics simulation Immune simulation

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Tungsten-based nanocatalysts with different structures for visible light responsive photocatalytic degradation of bisphenol A

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Journal of Environmental Sciences 2024年第5期139卷 569-588页

作者： Hai Bang Truong Thi Thu Loan Doan nguyen Tien Hoang nguyen Van Tam Minh kim nguyen Le Gia Trung Jin Seog Gwag nguyen Tien Tran Optical Materials Research Group Science and Technology Advanced InstituteVan Lang UniversityHo Chi Minh CityViet Nam Faculty of Applied Technology School of TechnologyVan Lang UniversityHo Chi Minh CityViet Nam The University of Da Nang University of Science and Technology54 Nguyen Luong BangDa NangViet Nam The University of Da Nang University of Science and Education459 Ton Duc Thang St.Lien ChieuDa Nang 550000Viet Nam Institute of Veterinary Science and Technology 31ha zoneTrau QuyGia LamHa Noi 12400Viet Nam Department of Physics Yeungnam UniversityGyeongsanGyeongbuk 38541Republic of Korea Center for Advanced Chemistry Institute of Research and DevelopmentDuy Tan University03 Quang TrungDa Nang 550000Viet Nam Faculty of Natural Sciences Duy Tan University03 Quang TrungDa Nang 550000Viet Nam

Environmental pollution,such as water contamination,is a critical issue that must be absolutely ***,three different morphologies of tungsten-based photocatalysts(WO_(3)nanorods,WO_(3)/WS_(2)nanobricks,WO_(3)/WS_(2)nanorods)are made using a simple hydrothermal method by changing the solvents(H_(2)O,DMF,aqueous HCl solution).The as-prepared nanocatalysts have excellent thermal stability,large porosity,and high *** results show all materials have good photocatalytic activity in aqueous media,with WO_(3)/WS_(2)nanorods(NRs)having the best activity in the photodegradation of bisphenol A(BPA)under visible-light *** may originate from increased migration of charge carriers and effective prevention of electron–hole recombination in WO_(3)/WS_(2)NRs,whereby this photocatalyst is able to generate more reactive·OH and·O_(2)^(–)species,leading to greater photocatalytic *** 99.6% of BPA is photodegraded within 60 min when using 1.5 g/L WO_(3)/WS_(2)NRs and 5.0 mg/L BPA at pH ***,the optimal conditions(pH,catalyst dosage,initial BPA concentration)for WO_(3)/WS_(2)NRs are also elaborately *** rod-like heterostructures are expressed as potential catalysts with excellent photostability,efficient reusability,and highly active effectivity in different types of *** particular,the removal efficiency of BPA by WO_(3)/WS_(2)NRs reduces by only 1.5% after five recycling runs and even reaches 89.1%in contaminated lake *** study provides promising insights for the nearly complete removal of BPA from wastewater or different water resources,which is advantageous to various applications in environmental remediation.

关键词： Photodegradation Bisphenol A Tungsten-based nanocatalyst Structure Nanorod

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Construction of a High‑Performance Composite Solid Electrolyte Through In‑Situ Polymerization within a Self‑Supported Porous Garnet Framework

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Nano-Micro Letters 2024年第5期16卷 56-70页

作者： An‑Giang nguyen Min‑Ho Lee Jaekook kim Chan‑Jin Park Department of Materials Science and Engineering Chonnam National University77 Yongbong‑roBuk‑guGwangju 61186South Korea

Composite solid electrolytes(CSEs)have emerged as promising candidates for safe and high-energy–density solid-state lithium metal batteries(SSLMBs).However,concurrently achieving exceptional ionic conductivity and interface compatibility between the electrolyte and electrode presents a significant challenge in the development of high-performance CSEs for *** overcome these challenges,we present a method involving the in-situ polymerization of a monomer within a self-supported porous Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12)(LLZT)to produce the *** synergy of the continuous conductive LLZT network,well-organized polymer,and their interface can enhance the ionic conductivity of the CSE at room ***,the in-situ polymerization process can also con-struct the integration and compatibility of the solid electrolyte–solid electrode *** synthesized CSE exhibited a high ionic conductivity of 1.117 mS cm^(-1),a significant lithium transference number of 0.627,and exhibited electrochemical stability up to 5.06 V ***/Li+at 30℃.Moreover,the Li|CSE|LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2) cell delivered a discharge capacity of 105.1 mAh g^(-1) after 400 cycles at 0.5 C and 30℃,corresponding to a capacity retention of 61%.This methodology could be extended to a variety of ceramic,polymer electrolytes,or battery systems,thereby offering a viable strategy to improve the electrochemical properties of CSEs for high-energy–density SSLMBs.

关键词： Scalable tape-casting method Self-supported porous Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12) Composite solid electrolyte LiF-and B-rich interphase layers

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越南胡志明市外语信息大学汉语口语课现状分析及教学设计

越南胡志明市外语信息大学汉语口语课现状分析及教学设计

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作者：阮氏金鸳（nguyen THI kim uyen）鲁东大学

学位级别：硕士

中越交流不断发展,需要更多双语人才的有效支撑。因此,我们越南的汉语学习者与日俱增,开设中文专业的高校也日见其多。为了提高汉语知识和技能,学校以听力、口语、写作、阅读设置为主干课型。而要真正实现交际,汉语口语占有重要的位置... 详细信息

中越交流不断发展,需要更多双语人才的有效支撑。因此,我们越南的汉语学习者与日俱增,开设中文专业的高校也日见其多。为了提高汉语知识和技能,学校以听力、口语、写作、阅读设置为主干课型。而要真正实现交际,汉语口语占有重要的位置。通过口语课培养学生实用口语。口语际能力是所有学校的共识。然而很多学习者在毕业之后交际方面仍然遇到障碍,这与口语课教学有难以摆脱的干系。为了解越南本土口语课教学现状,笔者选择了曾经就读的越南胡志明市外语信息大学作为主要研究对象,通过实地听课、问卷调查、现场访谈等方法分析口语课目前现状,发现存在的问题,并在分析问题的基础上,设计了适合该校口语课教学的“i+1情景教学法”,并据此进行了教学设计进而进行了教学实践。在分析教学实践效果的基础上,对该校口语课教学提出了多方面的建议。希望能“取长补短”,改善口语教学,为越南本土口语教学提供一定的借鉴和参考。本文共分五个部分。第一章是绪论,首先是选题缘由,接着是研究目的与意义。其后介绍了研究现状,说明了研究的对象及方法。第二章介绍了外语信息大学中文系及其口语课教学的基本情况;笔者利用专业实习的时间,深入该校口语课课堂,总结了初、中级口语课堂的真实情况;然后采用问卷调查,对调查结果进行较为全面的分析总结。认为存在问题主要为教师主导过度讲练失当、课堂过多依赖母语、输入与输出程度均不适宜、实践性不足交际性差等问题。第三章在分析口语课问题的基础上,结合口语教学相关理论,创新设计适合该校的“i+1情景教学法”,即在传统情景法教学的基础上,每个教学环节都增加适量的视频、音频、中外对比、中教在线辅助等方式。文章分析了其可行性,并运用该方法进行了针对外语信息大学口语课的教学设计。第四章是按照教学设计进行了教学实践,并从学生评价、教师反思两方面分析了教学效果。在此基础上从教师、学生、教材、学校四个角度对该校口语课提出了多方面改进建议。第五章是结语部分,总结了研究的主要发现,并指出本研究的不足之处。

关键词：胡志明市外语信息大学汉语口语课 i+1情景教学法教学设计教学实践

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Integrating immunoinformatics and computational epitope prediction for a vaccine candidate against respiratory syncytial virus

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Infectious Disease Modelling 2024年第3期9卷 763-774页

Respiratory syncytial virus(RSV)poses a significant global health threat,especially affecting infants and the *** this,the present study proposes an innovative approach to vaccine design,utilizing immunoinformatics and computational *** analyzed RSV's structural proteins across both subtypes A and B,identifying potential helper T lymphocyte,cytotoxic T lymphocyte,and linear B lymphocyte *** such as antigenicity,allergenicity,toxicity,and cytokine-inducing potential were rigorously ***,we evaluated the conservancy of these epitopes and their population coverage across various RSV *** comprehensive analysis identified six major histocompatibility complex class I(MHC-I)binding,five MHC-II binding,and three B-cell *** were integrated with suitable linkers and adjuvants to form the ***,molecular docking and molecular dynamics simulations demonstrated stable interactions between the vaccine candidate and human Toll-like receptors(TLR4 and TLR5),with a notable preference for *** simulation analysis underscored the vaccine's potential to elicit a strong immune *** study presents a promising RSV vaccine candidate and offers theoretical support,marking a significant advancement in vaccine development ***,the promising in silico findings need to be further validated through additional in vivo studies.

关键词： Respiratory syncytial virus Multiepitope vaccine Immunoinformatics Docking molecular Molecular dynamics simulation Immune simulation

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Adiponectin restores the obesity-induced impaired immunomodulatory function of mesenchymal stromal cells via glycolytic reprogramming

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Acta Pharmaceutica Sinica B 2024年第1期14卷 273-291页

作者： Duc-Vinh Pham Thi-Kem nguyen Bao-Loc nguyen Jong-Oh kim Jee-Heon Jeong Inho Choi Pil-Hoon Park Department of Pharmacology Hanoi University of PharmacyHanoi 100000Viet Nam College of Pharmacy Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Medical Biotechnology Yeungnam UniversityGyeongsan 38541Republic of Korea Research Institute of Cell Culture Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Precision Medicine School of MedicineSungkyunkwan UniversitySuwon 16419Republic of Korea

Obesity has been known to negatively modulate the life-span and immunosuppressive potential of mesenchymal stromal cells(MSC).However,it remains unclear what drives the compromised potency of obese *** this study,we examined the involvement of adiponectin,an adipose tissuederived hormone,in obesity-induced impaired therapeutic function of ***-induced obesity leads to a decrease in serum adiponectin,accompanied by impairment of survival and immunomodulatory effects of adipose-derived MSC(ADSC).Interestingly,priming with globular adiponectin(gAcrp)improved the immunomodulatory potential of obese *** effects were also observed in lean *** addition,gAcrp potentiated the therapeutic effectiveness of ADSC in a mouse model of DSS-induced ***,while obesity inhibited the glycolytic capacity of MSC,gAcrp treatment induced a metabolic shift toward glycolysis through activation of adiponectin receptor type 1/p38 MAPK/hypoxia inducible factor-1a *** findings suggest that activation of adiponectin signaling is a promising strategy for enhancing the therapeutic efficacy of MSC against immune-mediated disorders.

关键词： Adiponectin Adipose-derived stromal cells Colitis Glycolytic induction HIF1a Immunomodulation Mesenchymal stromal cells Obesity

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Machine learning-guided accelerated discovery of structure-property correlations in lean magnesium alloys for biomedical applications

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Journal of Magnesium and Alloys 2024年第6期12卷 2267-2283页

作者： Sreenivas Raguraman Maitreyee Sharma Priyadarshini Tram nguyen Ryan McGovern Andrew kim Adam J.Griebel Paulette Clancy Timothy P.Weihs Department of Materials Science and Engineering Johns Hopkins University3400 N Charles StBaltimore21218MDU.S.A Hopkins Extreme Materials Institute Johns Hopkins University3400 N Charles StBaltimore21218MDU.S.A Department of Chemical and Biomolecular Engineering Johns Hopkins University3400 N Charles StBaltimore21218MDU.S.A Translational Tissue Engineering Center Johns Hopkins School of Medicine400 N BroadwayBaltimore21231MDU.S.A Department of Biomedical Engineering Johns Hopkins University3400 N Charles StBaltimore21218MDU.S.A Research and Development Fort Wayne Metals Research ProductsLLC9609 Ardmore AveFort Wayne46809INU.S.A Department of Mechanical Engineering Johns Hopkins University3400 N Charles StBaltimore21218MDU.S.A

Magnesium alloys are emerging as promising alternatives to traditional orthopedic implant materials thanks to their biodegradability,biocompatibility,and impressive mechanical ***,their rapid in-vivo degradation presents challenges,notably in upholding mechanical integrity over *** study investigates the impact of high-temperature thermal processing on the mechanical and degradation attributes of a lean Mg-Zn-Ca-Mn alloy,*** rapid,cost-efficient characterization methods like X-ray diffraction and optical microscopy,we swiftly examine microstructural changes post-thermal *** Pearson correlation coefficient analysis,we unveil the relationship between microstructural properties and critical targets(properties):hardness and corrosion ***,leveraging the least absolute shrinkage and selection operator(LASSO),we pinpoint the dominant microstructural factors among closely correlated *** findings underscore the significant role of grain size refinement in strengthening and the predominance of the ternary Ca_(2)Mg_(6)Zn_(3)phase in corrosion *** suggests that achieving an optimal blend of strength and corrosion resistance is attainable through fine grains and reduced concentration of ternary *** thorough investigation furnishes valuable insights into the intricate interplay of processing,structure,and properties in magnesium alloys,thereby advancing the development of superior biodegradable implant materials.

关键词： Magnesium alloys Machine learning Corrosion Mechanical properties Rapid characterization

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Interfacial engineering through lead binding using crown ethers in perovskite solar cells

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Journal of Energy Chemistry 2024年第5期92卷 263-270页

作者： Sun-Ju kim YeonJu kim Ramesh Kumar Chitumalla Gayoung Ham Thanh-Danh nguyen Joonkyung Jang Hyojung Cha Jovana Milić Jun-Ho Yum Kevin Sivula Ji-Youn Seo Department of Nano Fusion Technology Pusan National UniversityBusan 46241Republic of Korea Laboratory for Molecular Engineering of Optoelectronic Nanomaterials Institute of Chemical Sciences and EngineeringÉcole Polytechnique Fédérale de Lausanne(EPFL)1015 LausanneSwitzerland Department of Energy Convergence and Climate Change Kyungpook National UniversityDaegu 41566Republic of Korea Department of Hydrogen and Renewable Energy Kyungpook National UniversityDaegu 41566Republic of Korea Adolphe Merkle Institute University of FribourgCH-1700 FribourgSwitzerland

In the domain of perovskite solar cells(PSCs),the imperative to reconcile impressive photovoltaic performance with lead-related issue and environmental stability has driven innovative *** study pioneers an approach that not only rectifies lead leakage but also places paramount importance on the attainment of rigorous interfacial *** ethers,notably benzo-18-crown-6-ether(B18C6),were strategically integrated at the perovskite-hole transport material *** ethers exhibit a dual role:efficiently sequestering and immobilizing Pb^(2+)ions through host-guest complexation and simultaneously establishing a robust interfacial passivation *** crown ether candidates,guided by density functional theory(DFT)calculations,demonstrated proficiency in binding Pb2+ions and optimizing interfacial *** devices incorporating these materials achieved exceptional power conversion efficiency(PCE),notably 21.7%for B18C6,underscoring their efficacy in lead binding and interfacial *** techniques,including time-of-flight secondary ion mass spectrometry(ToF-SIMS),ultraviolet photoelectron spectroscopy(UPS),time-resolved photoluminescence(TRPL),and transient absorption spectroscopy(TAS),unequivocally affirmed Pb^(2+)ion capture and suppression of non-radiative ***,these PSCs maintained efficiency even after enduring 300 h of exposure to 85%relative *** research underscores the transformative potential of crown ethers,simultaneously addressing lead binding and stringent interfacial passivation for sustainable PSCs poised to commercialize and advance renewable energy applications.

关键词： Perovskite solar cells Interfacial passivation Crown ether materials Stability

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