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Automotive Innovation 2020年第1期3卷 30-41页

作者： Craig K.Allison neville a.stanton Solent University East Park TerraceSouthampton SO140YNUK Transportation Research Group University of SouthamptonBoldrewood Innovation CampusSouthampton SO167QFUK

The design with intent(DwI)toolkit assists designers in creating novel designs and ***,however,is not constrained to any degree,making it impossible to know whether the produced designs adequately account for users’*** contrast,cognitive work analysis(CWA)is a human factors research tool that seeks to map a system and account for users’needs,yet does not provide clear guidelines for progressing such analysis into workable designs with which users can *** paper seeks to present a proof-of-concept investigation to demonstrate that DwI can be suitably constrained and validated by insights gained from ***,in turn,benefits by having a suitable toolkit for progressing *** teams of individuals without design backgrounds were able to develop mock-up in-vehicle interfaces aimed at reducing fuel *** teams were able to use DwI toolkit to articulate the genesis of their ideas,which in turn could be directly linked to system needs identified within CWA.

关键词： Design with intent Cognitive work analysis Interface design Eco-driving

Automated Vehicle Handover Interface Design:Focus Groups with Learner,Intermediate and Advanced Drivers

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Automotive Innovation 2020年第1期3卷 14-29页

作者： Jediah R.Clark neville a.stanton Kirsten M.A.Revell Human Factors Engineering Team Transportation Research GroupBoldrewood Innovation CampusUniversity of SouthamptonBurgess RoadSouthampton SO167QFUK

Conditionally and highly automated vehicles will require drivers to take control as a result of a non-emergency,such as a geographical,terrain,capability or design *** is anticipated that these events will provide the driver with a sufficient amount of time to prepare themselves for the transition of *** study explores conditionally and highly automated vehicle transitions of control by asking how drivers of differing skill levels(learner,intermediate and advanced)approach the task of designing an interface responsible for making transitions safer,more usable and more *** focus groups generated detailed designs for vehicle-to-driver transitions in an 1-h and a 10-min“out-of-the-loop”scenarios and transitions from driver to *** show great variation in the approaches taken by each skill group(e.g.,the reliance on visual interfaces for awareness assist and viewpoints on issues such as multimodal displays).Customization was a common theme throughout,with drivers desiring the option to adjust alert timings and modalities in which information is *** paper presents these designs along with a detailed comparison of group designs and implements distributed situation awareness theory to discuss findings and draw conclusions.

关键词： Handover Takeover Level 3 automation Interface design Automobile

Usability Assessment of Steering Wheel Control Interfaces in Motorsport

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Automotive Innovation 2020年第1期3卷 42-52页

作者： James W.H.Brown neville a.stanton Kirsten M.A.Revell University of Southampton SouthamptonUK

In order to assess the usability of steering wheel control interfaces in motorsport,it is necessary to employ a set of appropriate *** method selection process first involves identifying the relevant motorsport-based usability *** unique factors associated with context of use in motorsport are then *** are employed to synthesize a set of key performance indicators(KPIs)that require specific *** first KPI relates to error rates;these should be minimized,particularly under high cognitive load on the *** second KPI involves task times;these should be minimized not just to reduce distraction,but also to improve competitive *** third KPI states that usability should be optimized to minimize visual *** fourth KPI advocates the minimizing of interface task load to reduce the effect on the primary *** final KPI states that interface functionality should be easy to learn and *** KPIs provide clear goals to guide the identification of the most appropriate methods for each aspect of *** categories are devised and sets of appropriate methods selected based on the *** then combine into a toolset with an associated application process with the overall goal of providing a means by which motorsport interfaces may be both analysed and improved.

关键词： Usability Motorsport Steering wheel Analysis Assessment

Mitochondrial therapeutics and mitochondrial transfer for neurodegenerative diseases and aging

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Neural Regeneration Research 2025年第3期20卷 794-796页

作者： neville Ng Michelle Newbery Nicole Miles Lezanne Ooi Molecular Horizons and School of Chemistry and Molecular Bioscience University of WollongongWollongongNSWAustralia

Mitochondrial dysfunction and neurodegeneration:Progressive neurodegenerative diseases affect a significant proportion of the population;in a single year,there are as many as 276 million disabilities and 9 million dea... 详细信息

关键词： degenerative diseases Mitochondrial

Amyloid pores in mitochondrial membranes

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Neural Regeneration Research 2021年第11期16卷 2225-2226页

作者： neville Vassallo Department of Physiology&Biochemistry Faculty of Medicine and SurgeryUniversity of MaltaMsida MSD 2080Malta

Neurodegenerative diseases of the amyloid type include common conditions such as Alzheimer’s disease,Parkinson’s disease,Huntington’s disease and amyotrophic lateral *** the fact that the phenotypes of these neuropathic maladies differ widely,ranging from cognitive to motor and psychotic disturbances,they are all characterized by the pathological accumulation and deposition in the central nervous system of well-ordered protein aggregates known as amyloid *** evidence indicates that rather than the end-stage mature fibrils,however,it is the smaller,metastable intermediate forms(known as oligomers)of the aggregated protein and peptides which represent the most neurotoxic species(Chiti and Dobson,2017).One suggested mechanism for such toxicity appears to involve the ability of oligomers to interact with plasma membranes whilst inducing cell leakage(Surguchov et al.,2017).However,contemporary work increasingly points to mitochondria,and hence mitochondrial membranes,as preferential targets for the pathogenic action of oligomers in the neuronal cell(Ghio et al.,2016).

关键词： Huntington membranes amyloid

The evolving ENSO observing system

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National Science Review 2018年第6期5卷 805-807页

作者： Dake Chen neville Smith William Kessler State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of Oceanography

El Nio–Southern Oscillation (ENSO)is by far the most energetic and influential short-term climate variability on our planet, originating from an instability of the large-scale ocean-atmosphere interaction in the tr... 详细信息

关键词： The evolving ENSO observing system TAO

Comparisons of corrosion behaviour for X65 and low Cr steels in high pressure CO2-saturated brine

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Journal of Materials Science & Technology 2020年第6期41卷 21-32页

作者： Yong Hua Sikiru Mohammed Richard Barker Anne neville Institute of Functional Surfaces School of Mechanical Engineering University of Leeds Leeds LS2 9JT United Kingdom

Appropriate materials for injection pipelines and tubing for carbon dioxide geologic storage is fundamental to ensure asset integrity and save *** paper evaluates the corrosion behaviour of X65,1Cr,3Cr and 5Cr,which have the potential to be injection pipeline/tubing *** influence of steel Cr content on the general and localised corrosion behaviour was investigated at time periods from 6 to 192 h at 60℃and 100 *** evolution,morphology and chemistry of corrosion products on the surface of each material were evaluated using a combination of scanning electron microscopy,energy dispersive X-ray spectroscopy and X-ray diffraction and related to their overall corrosion *** indicate that prior to the formation of protective films on the steel surfaces,the resistance of the materials to corrosion increase with increasing Cr content(Corrosion resistance:X651Cr>3Cr>5Cr).In terms of the corrosion products on X65,both inner amorphous and outer crystalline corrosion layers consist of *** the Cr-containing steels,the outer layer also comprises FeCO3,but the inner layer is enriched with Cr,and is predominantly amorphous Cr(OH)*** extent of localised corrosion(determined using surface profilometry)is noticeably less for X65 compared to the Cr-containing *** paper raises questions about the benefits that low Cr steels offer towards extending component design life compared to carbon steel under the test conditions considered here.

关键词： Carbon dioxide Corrosion X65 Low-Cr steels Iron carbonate Chromium hydroxide

A numerical model to simulate the transient frictional viscoelastic sliding contact

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Friction 2024年第2期12卷 319-339页

作者： Dongze WANG Gregory de BOER Anne neville Ali GHANBARZADEH School of Mechanical Engineering University of LeedsLeeds LS29JTUK

Sliding motion has always been one of the major concerns when it comes to the analysis of viscoelastic contact problems.A new model simulating the transient sliding contact of smooth viscoelastic surfaces is developed in this *** taking the dry contact friction and the coupling between shear tractions and normal pressure into account,the effect of the early partial slip period,which is often neglected in the study of viscoelastic sliding contact problems,is investigated *** with solutions based on the frictionless assumption,the steady-state pressure profile is found to be slightly different under the effect of the partial slip regime,including a lower peak pressure and the shift of the contacting region in the direction opposite to the sliding ***,the time required for the viscoelastic contact to reach its steady state is delayed owing to the partial slip period preceding the global sliding motion.

关键词： contact mechanics frictional sliding viscoelasticity viscoelastic friction

Exercise for stroke prevention

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Stroke & Vascular Neurology 2018年第2期3卷 59-68页

作者： Peter L Prior neville Suskin Lawson Health Research Institution LondonOntarioCanada St.Josephs Health Care Cardiac Rehabilitation and Secondary Prevention Program LondonOntarioCanada Department of Medicine(Cardiology) Schulich School of Medicine&DentistryWestern UniversityLondonOntarioCanada

We review evidence concerning exercise for stroke *** biological reasons suggest that exercise would be important in preventing *** definitive randomised controlled trials evaluating the impact of physical activity(PA)and exercise on preventing stroke and mortality are lacking,observational studies,small randomised controlled trials and meta-analyses have provided evidence that PA and exercise favourably modify stroke risk factors,including hypertension,dyslipidaemia,diabetes,sedentary lifestyle,obesity,excessive alcohol consumption and tobacco *** is,therefore,important to understand the factors associated with poststroke PA/exercise and cardiorespiratory *** associated factors include self-efficacy,social support and quality of patients’relationships with health *** associated factors include logistical barriers,medical comorbidities,stroke-related deficits,negative exercise beliefs,fear of falling,poststroke fatigue,arthropathy/pain and *** research is needed to specify efficacious behavioural approaches to increase poststroke *** techniques probably include physician endorsement of exercise programmesto patients,enhancement of patient-professional relationships,providing patients an exercise rationale,motivational interviewing,collaborative goal-setting with patients,addressing logistical concerns,social support in programsmes,structured exercise programming,individualised behavioural instruction,behavioural diary recording,reviewing behavioural consequences of exercise efforts,reinforcing successful exercise *** programming without counselling may increase short-term activity;simple advice or information-giving is probably *** patients or those with cognitive impairment may need increased structure,with emphasis on behaviour per se,versus self-regulation *** support the latest American Heart Association/American Stroke Associati

关键词： prevention behaviour programming

Designing soft/hard double network hydrogel microsphere/UHMWPE composites to promote water lubrication performance

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Friction 2021年第3期9卷 551-568页

作者： Chaobao WANG Xiuqin BAI Conglin DONG Zhiwei GUO Chengqing YUAN Anne neville School of Energy and Power Engineering Wuhan University of TechnologyWuhan 430063China Key Laboratory of Marine Power Engineering&Technology(Ministry of Transport) Wuhan University of TechnologyWuhan 430063China Institute of Functional Surfaces School of Mechanical EngineeringUniversity of LeedsLeeds LS29JTUnited Kingdom

Several soft tissues residing in the living body have excellent hydration lubrication properties and can provide effective protection during relative *** order to apply this advantage of soft matters in practical applications and try to avoid its disadvantage,such as swelling and weakening in water,a design strategy of a soft/hard double network(DN)hydrogel microsphere modified ultrahigh molecular weight polyethylene(UHMWPE)composite is proposed in this study.A series of microspheres of urea-formaldehyde(UF),polyacrylamide(PAAm)hydrogel,UF/PAAm double network,and their composites were *** mechanical properties,swelling,wettability,friction properties,and the lubrication mechanisms of the composites were *** results show that DN microspheres can have an excellent stability and provide hydration *** performance of 75 DN-1 composite was superior to *** finding will provide a novel strategy for the development of water-lubricated materials and have wide application in engineering fields.

关键词： double network microsphere composite friction properties hydration lubrication