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Therapeutic Benefits of Vernonia amygdalina in the Treatment of Inflammation and Its Associated Diseases

Clinical Complementary Medicine and Pharmacology 2024年第1期4卷 44-53页

作者： Du-Bois Asante Gideon Akuamoah Wiafe Korantema Mawuena Tsegah nelson kwabla domey Department of Forensic Sciences School of Biological SciencesCollege of Agriculture and Natural SciencesUniversity of Cape CoastPMBCape CoastGhana Department of Biomedical Sciences School of Allied Health SciencesCollege Health and Allied SciencesUniversity of Cape CoastPMBCape CoastGhana School of Medical Sciences College Health and Allied SciencesUniversity of Cape CoastPMBCape CoastGhana

Background:In the presence of a stimulus that disrupts homeostasis,the body elicits a response known as *** inflammatory response is expected to restore the normal functioning of the body and initiate healing where ***,the persistent activity of acute inflammation results in chronic inflammation which causes adverse consequences associated with diseases such as diabetes and *** traditional medical practice,Vernonia amygdalina is used to treat several ailments such as malaria,fever,diabetes,and inflammatory conditions such as those related to pain and ***:This review seeks to explore and discuss the therapeutic benefits of *** in the treatment of inflammation and its associated ***:We reviewed the scientific literature indexed in PubMed,ScienceDirect and Springer,and discussed the reported anti-inflammatory properties of *** and its curative activity in inflammation-associated ***:A total of 30 published articles were identified describing the therapeutic effect of *** in predominately experimental *** anti-inflammatory properties of *** have been linked to the presence of bioactive phytoconstituents predominantly present in the leaves of the ***:Multiple studies have demonstrated that the aqueous and ethanolic extracts of *** can inhibit the production of proinflammatory cytokines and enzymes in inflammatory cells,reducing inflammation and its associated *** critically appraise the current evidence,and discuss the potential use of this medicinal plant in the treatment of inflammatory conditions.

关键词： Vernonia amygdalina Inflammation Cytokines Wound healing Analgesic Antipyretic

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