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Same day colposcopic examination and loop electrosurgical excision procedure (LEEP) presents minimal overtreatment and averts delay in treatment of cervical intraepithelial neoplasia in Kenyatta National Hospital, Kenya

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Open Journal of Obstetrics and Gynecology 2013年第3期3卷 313-318页

作者： Kays Muruka Mugo R. nelly Wanyoike Gichuhi Kihara Anne-Beatrice Cheserem J. Eunice Kosgei J. Rose Department of Obstetrics and Gynecology University of Nairobi Nairobi Kenya Kenya Medical Research Institute Nairobi Kenya Kenyatta National Hospital Department of Research and Special Programs Nairobi Kenya Ministry of Medical Services Kabarnet District Hospital Baringo Kenya

Background: Screening for cancer of the cervix at Kenyatta National Hospital (KNH), follows the recommended three-step strategy;Papanicolaou (Pap) smear, colposcopy/biopsy and loop electrosurgical excision procedure (LEEP)/biopsy. This approach poses the following challenges: multiple clinic visits, costly, time consuming, long turnaround time to treatment, non-compliance and loss-to-follow-up. Objective: To determine the agreement between histologies following colposcopy and LEEP amongst women in KNH as a forerunner for opportunity to shift from the three-step approach to the two-step “see and treat” (same-day colposcopy and LEEP) approach. Methods: This was a retrospective descriptive cohort of Women who underwent LEEP procedure between January 2008 and 31st December 2010 following the three-step approach at KNH, Kenya. Results: A total of 124 patients out of the 132 patients who underwent LEEP were included in the analysis. The 8 patients excluded had missing files. HIV infected, uninfected or unknown women are similar socio-demographically. The mean (SD) age for the HIV infected, uninfected and unknown is 37 (6), 33 (10) and 35 (9) years respectively. Colposcopic and LEEP biopsy histology within patients demonstrated a high weighted kappa statistics agreement of 84%. LEEP increased diagnosis of invasive cancer. Patients had a median (IQR) 5 (4 - 6) clinic visits from Pap smear to LEEP treatment. It took median (IQR) 55 (27 - 116) days between Pap smear to colposcopy result and 167 (101 - 276) days between Pap smear results to LEEP treatment. If a LEEP procedure were to be performed in this cohort of women on the same day of the colposcopy biopsy a median (IQR) 77 (55 - 137) days could have been saved. Conclusion: There is a high agreement between colposcopy and LEEP biopsies in our setting offering a window of opportunity to perform “See and Treat” same-day colposcopy and LEEP treatment procedure, skipping the colposcopy biopsy stage.

关键词： Colposcopy Loop Electrosurgical Excision Procedure (LEEP) CIN Cervical Cancer Screening

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GIS-Hydrogeochemical Model of the YaoundéFractured Rock Aquifer, Cameroon: Aquifer Setting, Seasonal Variations in Groundwater-Rock Interaction and Water Quality

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Journal of Geoscience and Environment Protection 2019年第5期7卷 232-263页

作者： Richard Ayuk II Akoachere Omabgemi Omoloju Yaya Sonia Ebot Egbe Thomson Areakpoh Eyong Bihmimihney nelly Nji Diana Besem Tambe Department of Geology University of Buea Buea Cameroon National Water Resources Institute Kaduna Nigeria Advanced School of Public Works Yaoundé Cameroon

This study of the gneiss-fractured-rock aquifer in Yaoundé capital of Cameroon determines: the aquifer setting-flow systems, the aquifer type, seasonal variations in rock-water interactions, evolution of the hydrogeochemical processes, physicochemical parameters and the suitability for domestic-agro-industrial use of the groundwater. Physicochemical field tests were carried out on 445 wells during four seasons for EC, pH, TDS, Temperature and static water level from July 2016 to May 2017. 90 well samples were analyzed 45 samples per season: wet/dry. 38 borewell logs were used together with structural data to determine the aquifer setting. The field physico-chemical and laboratory analysis data of well samples were mounted unto various GIS software platforms: Global mapper, AqQa, Aquachem, Rockworks, Logplot7, Surfer and ArcGIS, to get indices/parameters/figures, by use of Durov’s, Piper’s and Gibbs diagrams, Water quality index WQI, USSL ratio, Sodium Absorption ratio SAR, Percent sodium %Na, Kelly Ratio KR, Magnesium Absorption Ratio MAR, Total Hardness TH, Residual Sodium Carbonate RSC and Permeability Index PI that were determined. The process of groundwater ions acquisition is three-fold: by recharge through atmospheric precipitation, by ion exchange/simple dissolution between the rock-groundwater and by groundwater mixing in its flow path. Water types are Ca-HCO3, Mg-HCO3 and Mg-Cl while hydrogeochemical facies are Ca-Mg-HCO3 and Ca-Mg-Cl-SO4. Most water samples are fresh, potable and soft all seasons. The hydrogeological conceptual model is that of a three-layered single phreatic fractured-rock-aquifer while other researchers postulated a two-aquifer, phreatic and semi-confined, two-layered model.

关键词： GIS-Hydrogeochemical Model Groundwater-Rock Interaction Fractured Rock Aquifer Aquifer Setting Water Quality Yaoundé Cameroon

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何时

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疯狂英语（阅读版） 2013年第11期 32-33页

作者： Michael Bublé nelly Furtado 小狐

告诉我你何时才会属于我告诉我何时，何时。

关键词：英语教学教学方法阅读教学课外阅读

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Plastic Surgery:Worth the Risks?

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新高考(英语进阶) 2012年第Z1期 8-8页

作者： nelly

随着物质生活的日益丰富,人们对美的追求也越来越花样繁多。不仅服饰、发型要匹配,脸型和身材也要"不甘示弱"。那么,如何才能实现对美的极致追求呢?整形手术成为越来越多的人追求美貌与好身材的方式。整形手术,是帮助人们获得青春与美... 详细信息

随着物质生活的日益丰富,人们对美的追求也越来越花样繁多。不仅服饰、发型要匹配,脸型和身材也要"不甘示弱"。那么,如何才能实现对美的极致追求呢?整形手术成为越来越多的人追求美貌与好身材的方式。整形手术,是帮助人们获得青春与美貌的助推

关键词：整形手术 Plastic Surgery:Worth the Risks

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companies to check Every Package Mailed

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新高考(英语进阶) 2012年第4期 6-6页

作者： nelly

近日,北京出台政策要求快递公司员工必须将自己的姓名或者工号印在邮件上,并且要打开包裹检查。消息一经传出就引发热议,有人认为这样能保证投递准确,还有人则持否定意见,认为这样严重侵犯顾客隐私。究竟孰是孰非呢?

关键词： companies to check Every Package Mailed

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Association of problematic internet use with depression,impulsivity,anger,aggression,and social anxiety:Results of a national study among Lebanese adolescents

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Pediatric Investigation 2021年第4期5卷 255-264页

作者： Chadia Haddad Diana Malaeb Hala Sacre Jad Bou Khalil Wael Khansa Roula Al Hajj nelly Kheir Sylvia Saade Sahar Obeid Souheil Hallit Research Department Psychiatric Hospital of the CrossJal EddibLebanon INSERM Univ.LimogesCHU EsquirolIRDU1094 Tropical NeuroepidemiologyInstitute of Epidemiology and Tropical NeurologyGEISTLimogesFrance School of Pharmacy Lebanese International UniversityBeirutLebanon Life sciences and health department Paris-Est UniversityParisFrance INSPECT-LB:Institut National de SantéPublique Epidémiologie Clinique et ToxicologieBeirutLebanon Faculty of Medicine and Medical Sciences Holy Spirit University of Kaslik(USEK)JouniehLebanon Faculty of Arts and Sciences Holy Spirit University of Kaslik(USEK)JouniehLebanon

Importance:Several studies conducted worldwide(mostly in Western countries)highlighted the negative effects of problematic internet use,particularly among adolescents aged 12 to 17,including depression,impulsivity,aggression,and social fear and *** Lebanon,literature on the prevalence and impact of problematic internet use among adolescents is ***:This study aim was to study the association between problematic internet use and depression,impulsivity,anger,aggression and social phobia among Lebanese ***:A cross-sectional study was performed on 1103 young adolescents(14-17 years),recruited from October 2017 till April *** Internet Addiction Test(IAT)was used to evaluate the level of problematic internet *** were analyzed using the MANCOVA *** main independent variable of interest was the IAT,while the dependent variables included the psychological ***:The multivariate analysis taking the psychological scales as the dependent variables and the problematic internet use(IAT score)as an independent variable,showed that problematic internet use was associated with higher depression,impulsivity,aggression,anger,hostility and social ***:Problematic internet use has become an important health issue that should not be overlooked,particularly because of the increased use of the internet by *** programs on early exposure to the internet should be developed.

关键词： Problematic internet use Adolescents Depression Aggression Social phobia Hostility

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Ipsilateral breast tumor recurrence in early stage breast cancer patients treated with breast conserving surgery and adjuvant radiation therapy: Concordance of biomarkers and tumor location from primary tumor to in-breast tumor recurrence

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World Journal of Clinical Oncology 2020年第1期11卷 20-30页

作者： Juhi M Purswani Fauzia Shaikh S Peter Wu Jennifer Chun Kim Freya Schnabel nelly Huppert Carmen A Perez Naamit K Gerber Department of Radiation Oncology New York University School of MedicineNew YorkNY 10016United States Department of Surgery New York University School of MedicineNew YorkNY 10016United States

BACKGROUND Patients with an in-breast tumor recurrence(IBTR)after breast-conserving therapy have a high risk of distant metastasis and disease-related *** clinical parameters that increase risk for recurrence after IBTR remains a *** To describe primary and recurrent tumor characteristics in patients who experience an IBTR and understand the relationship between these characteristics and disease *** Patients with stage 0-II breast cancer treated with lumpectomy and adjuvant radiation were identified from institutional databases of patients treated from 2003-2017 at our *** survival(OS),disease-free survival,and local recurrence-free survival(LRFS)were estimated using the Kaplan Meier *** identified patients who experienced an isolated *** of hormone receptor status and location of tumor from primary to recurrence was *** effect of clinical and treatment parameters on disease outcomes was also *** We identified 2164 patients who met the eligibility *** median follow-up for all patients was 3.73[interquartile range(IQR)2.27-6.07]***-year OS was 97.7%(95%CI:96.8%-98.6%)with 28 deaths;5-year LRFS was 98.0%(97.2-98.8)with 31 *** identified 37 patients with isolated IBTR,19(51.4%)as ductal carcinoma in situ and 18(48.6%)as invasive disease,of whom 83.3%had an in situ *** time from initial diagnosis to IBTR was 1.97(IQR:1.03-3.5)*** information was available for 30 of 37 *** whole-breast dose was 40.5 Gy and 23 patients received a boost to the tumor ***-five of thirty-two(78.1%)patients had concordant hormone receptor status,HER-2 receptor status,and estrogen receptor(ER)(P=0.006)and progesterone receptor(PR)(P=0.001)status from primary to IBTR were significantly *** were no observed changes in HER-2 status from primary to *** concordance between quadrant of primary to IBTR was 10/19[(62.2%

关键词： Ipsilateral breast tumor recurrence Breast conservation Adjuvant radiation

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China to Ban Inserted Ads in TV Series

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新高考(英语进阶) 2012年第1期 5-5页

作者： nelly

新闻背景:近日,广电总局下发《〈广播电视广告播出管理办法〉的补充规定》,决定自2012年1月1日起,全国各电视台播出电视剧时,每集电视剧中间不得再以任何形式插播广告。禁令一出,几家欢喜几家愁。观众们拍手称快,总算不用忍受广告的"狂... 详细信息

新闻背景:近日,广电总局下发《〈广播电视广告播出管理办法〉的补充规定》,决定自2012年1月1日起,全国各电视台播出电视剧时,每集电视剧中间不得再以任何形式插播广告。禁令一出,几家欢喜几家愁。观众们拍手称快,总算不用忍受广告的"狂轰滥炸"了。电视台则表示损失巨大,前景堪忧。你的观点呢?

关键词： TV China to Ban Inserted Ads in TV Series

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Evaluation of the Physico-Chemical Quality and Potability of Groundwater Consumption in Department of Collines at Benin

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Journal of Geoscience and Environment Protection 2022年第1期10卷 29-48页

作者： Okoundé Kotchikpa Jean-Eudes Ringo Fernand Avahounlin Carine nelly Kélomé Ouassa Pierre Adjoa Mirande Hermione Adéké Expédit Wilfried Vissin Chaire Internationale de Physique Mathématique et Applications (CIPMA CHAIRE-UNESCO FAST UAC) Cotonou Benin Ecole Normale Supérieure (ENS UNSTIM) Natitingou Benin Département des Sciences e la Terre Université d’Abomey-Calavi Benin Département de Géographie et Aménagement du Territoire (DGAT FASHS UAC) Cotonou Benin

The purpose of this study is to assess the physical and chemical quality of borehole water intended for consumption in the collines department in Benin. At the end of a sampling campaign, twenty-one (21) drinking water points were sampled. Different physico-chemical parameters were measured using standard analysis methods. The results of the analysis of the samples, showed that the groundwater of the department of the hills is characterized by a neutral pH and an average electrical conductivity in accordance with the WHO and Benin standard relating to the potability of groundwater. With this pH neutrality which would be linked to the nature of geological formations made up of crystalline rocks, the water in the hills is moderately hard with hardness values of 208 mg/L on average for magnesium ions of 22.54 mg/L on average and calcium ions of the order of 46.03 mg/L on average at the scale of the various localities and an alkalinity is of 43.81 mg/L on average. The values between 0 and 163.91 mg/L are low in the South-East and very high, even exceeding the standard accepted by WHO in the West and North-East of the study area. This nitrate pollution and the fairly high levels of organic matter in total nitrogen observed in the groundwater of the hills could also have an impact on the vulnerability of the water table. And this pollution with nitrates associated with electrical conductivity and chloride levels modifies and degrades from one drinking water point to another the potability of und

关键词： Collines Department Physico-Chemical Parameters Groundwater Physico-Chemical Parameters Potability of Underground Water

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Fluorine in Water and Dental Fluorosis in a Community of Queretaro State Mexico

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Journal of Environmental Protection 2011年第6期2卷 744-749页

作者： Ma Lilia. A Juárez-López Rafael Huízar-álvarez nelly Molina-Frechero Francisco Murrieta-Pruneda Yazmin Cortés-Aguilera 不详

The community La Llave, Queretaro State, Mexico, has not been identified by the sanitary authorities as living in a hazard area related to dental fluorosis. However;a high concentration of fluoride is found in their drinking water causing them dental fluorosis. Physical-chemical analysis was carried out in the groundwater sources to determine the prevalence of dental fluorosis risk and caries accordingly to criteria of The World Health Organization, and 154 school children of ages 10 to 13 years were examined. As a result, 1.9 mg/L of fluorine concentration in drinking water was obtained;dental fluorosis presence was detected in the school children with an incidence of about 98%, in 47% of cases severe fluorosis with a dental caries index of 3.06 was traced. The groundwater sources in La Llave community contains fluorine above the limits dictated by Mexican regulations, producing serious repercussions on the health of school children, with an unnaturally high incidence of dental fluorosis.

关键词： Fluorosis DEAN Index Groundwater La Llave Querétaro Mexico

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