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Short, Medium, and Long-Term Stroke Mortality in Libreville and Associated Factors

Neuroscience & Medicine 2024年第1期15卷 39-50页

作者： Grass Aurelle Mambila Matsalou Jennifer Nyangui Mapaga Pupchen M. Gnigone Minka’a Pagbe Michael Chermine Mboumba Mboumba Christian Allognon Mahutondji Aissata Ibrahima Camara Annick A. Nsounda nelly diouf mbourou Michel-Arnaud Saphou-Damon Elsa Ayo Bivigou Philomene Kouna Ndouongo Neurology Department University Hospital of Libreville Libreville Gabon Cardiology Department University Hospitalof Libreville Libreville Gabon

Strokes are common around the world and especially in sub-Saharan Africa. They are responsible for severe sequelae and the majority of deaths. In Gabon, no study on stroke mortality has been conducted. Objective: To determine short, medium, long-term mortality and factors associated with long-term stroke mortality. Method: Our study took place in the Neurology Department of the University Hospital Center of Libreville (UHCL). It was a historical cohort study with descriptive and analytical purposes covering the period from June 1 to August 31, 2018 and taking into account hospitalized patients from January 1, 2013 to December 31, 2017. We conducted a comprehensive systematic recruitment of patients with stroke, 18 years old and more, and had been agreed to give information. We included all patients meeting the inclusion criteria. The data was gathered using Epi-Info 7 software. The CHI-2 test was used for the comparison of frequencies and the Student’s test, for comparison of means. Multivariate analysis with logistic regression allowed us to look for factors associated with long-term mortality. A result was statistically significant for a p 0.05 value. Results: At 3 months, 28 patients (18.1%) died, at 6 months thirty-one patients or 20.1% died. At 5 years old, fifty-three patients or 34.4% had died. The factors associated with long-term mortality, if the lost of sight were all alive were tobacco (p = 0.01) and stroke (p = 0.008). If all those who were lost to sight had died, no factor was associated with 5-year mortality. Conclusion: Stroke mortality must not be taken for granted, it can be underestimated because of the large number of lost sight. Measures must be put in place to strengthen post-stroke monitoring. .

关键词： Stroke Mortality Associated Factors Libreville

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Multifocal Spontaneous Intracerebral Hemorrhage about a Case and Review of the Literature

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Neuroscience & Medicine 2020年第1期11卷 12-19页

作者： Prince Eliot G. Sounga Bandzouzi Hugues Brieux Ekouele Mbaki Dina Happhia Motoula Latou Ghislain Armel Mpandzou Josue Diatewa Aimé Kaoudi nelly mbourou diouf Frida Ninelle Awam Amioth Vital Ebelebe Godefroy Charles Koubemba Paul Macaire Osou-Nguiet Department of Neurology Loandjili General Hospital Pointe-Noire Congo Faculty of Health Sciences Marien Ngouabi University Brazzaville Congo Department of Neurosurgery University Hospital of Brazzaville Brazzaville Congo Department of Neurosurgery Loandjili General Hospital Pointe-Noire Congo Department of Neurology University Hospital of Libreville Libreville Gabon Department of Radiology Loandjili General Hospital Pointe-Noire Congo

We describe the case of a spontaneous multifocal intracerebral hemorrhage in a Congolese subject presenting no risk factor. He is a 32-year-old subject with no particular history admitted for seizures in which the cerebral scanner has revealed spontaneous multifocal intracerebral hemorrhages. He only received medical treatment. It remains a very rare entity. The location of the hematoma is variable and is usually located in the basal ganglia due to chronic hypertension.

关键词： Intracerebral Hemorrhage Spontaneous Multifocal Seizures

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The Short-Term and Medium-Term Prognosis of a Stroke and the Factors of Poor Prognosis in Liberville

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Neuroscience & Medicine 2022年第4期13卷 135-144页

作者： Nyangui Mapaga Jennifer Gningone Pupchen Marylise Mambila Grass Aurelle diouf mbourou nelly Saphou-Damon Michel-Arnaud Nsounda Annick Andréa Camara Aissata Ibrahima Kouna Ndouongo Philomène Department of Neurology Centre Hospitalier Universitaire Libreville Libreville Gabon

Objectives: was to determine the factors influencing stroke prognosis in Libreville. Methods: This was a multicenter study prospective with a descriptive and analytical focus carried out from March 1st to July 31, 2014. Recruitment was systematic and exhaustive. The data collected was processed and analyzed using Epi-Info 3.3.5 software. Results: This study involved 66 patients including 27 male (40.9%) and 39 female (59.1%). Mean age was 55.1 +/? 15.3 years, mostly female. There were 57.5% ischemic stroke, 42.5% hemorrhagic stroke. The mean NIHSS was 7.8 +/? 6.6 at admission. Intra- hospital stroke mortality rates at 1 and 3 months were 7.6% and 9.1% respectively, ranging from 18.2% to 31.8%. The following factors were identified as associated with death at 1 month: age, high NIHSS at admission, high blood pressure, leukocytosis, hyperthermia and delay in admission. As for functional outcome, patients were relatively autonomous at discharge and factors associated with poor functional outcome (Rankin Conclusion: This study highlights many factors influencing prognosis of stroke. The poor prognostic factors were age, high NIHSS at admission, high blood pressure, hyperthermia, blood glucose, leukocytosis, delay in admission and length of hospital stay. Addressing these factors in the acute phase management strategies may improve the prognosis of stroke patients in Gabon.

关键词： Prognosis Stroke Libreville

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