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Magnetic anchor guidance for endoscopic submucosal dissection and other endoscopic procedures

World Journal of Gastroenterology 2017年第16期23卷 2883-2890页

作者： Mohamed Mortagy neal Mehta Mansour A Parsi Seiichiro Abe Tyler Stevens John J Vargo Yutaka Saito Amit Bhatt Department of Internal Medicine Homer Stryker MD School of MedicineWestern Michigan UniversityKalamazooMI 49008United States Department of Internal Medicine Medicine InstituteCleveland ClinicClevelandOH 44195United States Department of Gastroenterology and Hepatology Digestive Disease InstituteCleveland ClinicClevelandOH 44195United States Endoscopy Division National Cancer Center HospitalTokyo 104-0045Japan

Endoscopic submucosal dissection(ESD) is a wellestablished, minimally invasive treatment for superficial neoplasms of the gastrointestinal tract. The universal adoption of ESD has been limited by its slow learning curve, long procedure times, and high risk of complications. One technical challenge is the lack of a second hand that can provide traction, as in conventional surgery. reliable tissue retraction that exposes the submucosal plane of dissection would allow for safer and more efficient dissection. Magnetic anchor guided endoscopic submucosal dissection(MAGESD) has potential benefits compared to other current traction methods. MAG-ESD offers dynamic tissue retraction independent of the endoscope mimicking a surgeon's "second hand". Two types of magnets can be used: electromagnets and permanent magnets. In this article we review the MAG-ESD technology, published work and studies of magnets in ESD. We also review the use of magnetic anchor guidance systems in natural orifice transluminal endoscopic surgery and the idea of magnetic non-contact retraction using surface ferromagentization. We discuss the current limitations, the future potential of MAG-ESD and the developments needed for adoption of this technology.

关键词： Endoscopic submucosal dissection Gastric cancer Magnetic anchor guidance Esophageal cancer Magnets Traction Natural orifice transluminal endoscopic surgery

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Systematic review and meta-analysis of outcomes of anatomic repair in congenitally corrected transposition of great arteries

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World Journal of Cardiology 2020年第8期12卷 427-436页

作者： Arka Chatterjee neal J Miller Marc G Cribbs Amrita Mukherjee Mark A Law Division of Cardiovascular Diseases University of Alabama at BirminghamBirminghamAL 35294United States Department of Pediatric Cardiology University of Alabama at BirminghamBirminghamAL 35294United States Department of Epidemiology University of Alabama at Birmingham School of Public healthBirminghamAL 35233United States

BACKGrOUND Treatment of congenitally corrected transposition of great arteries(cc-TGA)with anatomic repair strategy has been considered superior due to restoration of the morphologic left ventricle in the systemic ***,data on long term outcomes are limited to single center reports and include small sample *** To perform a systematic review and meta-analysis for observational studies reporting outcomes on anatomic repair for *** MEDLINE and Scopus databases were queried using predefined criteria for reports published till December 31,*** reporting anatomic repair of minimum 5 cc-TGA patients with at least a 2 year follow up were *** was performed using Comprehensive meta-analysis v3.0 *** Eight hundred and ninety-five patients underwent anatomic repair with a pooled follow-up of 5457.2 patient-years(PY).Pooled estimate for operative mortality was 8.3%[95%confidence interval(CI):6.0%-11.4%].0.2%(CI:0.1%-0.4%)patients required mechanical circulatory support postoperatively and 1.7%(CI:1.1%-2.4%)developed post-operative atrioventricular block requiring a *** surviving initial surgery had a transplant free survival of 92.5%(CI:89.5%-95.4%)per 100 PY and a low rate of need for pacemaker(0.3/100 PY;CI:0.1-0.4).84.7%patients(CI:79.6%-89.9%)were found to be in New York Heart Association(NYHA)functional class I or II after 100 PY follow *** re-intervention rate was 5.3 per 100 PY(CI:3.8-6.8).CONCLUSION Operative mortality with anatomic repair strategy for cc-TGA is *** that,transplant free survival after anatomic repair for cc-TGA patients is highly *** of patients maintain NYHA I/II functional ***,monitoring for burden of re-interventions specific for operation type is very essential.

关键词： Congenitally corrected transposition of great arteries Anatomic repair Double switch operation Atrial switch rastelli Hemi-Mustard rastelli Atrio-ventricular block

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rain Music

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小学生时代（大嘴英语） 2022年第6期 20-23页

作者： neal Levin Shannon Day(图) 不详

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MIM Fe-2Ni-0.8C的烧结

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粉末冶金技术 2016年第3期34卷 232-238页

作者： neal Myers raman Baijal Pennsylvania State University Center for Innovative Sintered Products University Park PA 16802 Patrick King Hoeganaes Corporation Chmaminson NJ 08077

鉴于水雾化工艺比气雾化与化学法可节约成本,长期以来,在粉末注射成形工艺中使用水雾化粉末,一直是个值得注意的领域,在这个研究课题中,研究了水雾化Fe-2Ni粉末在研磨与接收状态下的烧结特性.研究了粒度、含碳量、加热速率、烧结温度与... 详细信息

鉴于水雾化工艺比气雾化与化学法可节约成本,长期以来,在粉末注射成形工艺中使用水雾化粉末,一直是个值得注意的领域,在这个研究课题中,研究了水雾化Fe-2Ni粉末在研磨与接收状态下的烧结特性.研究了粒度、含碳量、加热速率、烧结温度与气氛的变化.结果表明,除了烧结温度与气氛的变化外,对烧结体的密度影响最要的因素是颗粒大小、加热速率及表面的化学性质.研磨可改变表面的化学性质与减小颗粒大小,这二者都会使烧结件的密度增高。

关键词： MIM Fe-2Ni 烧结特性

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最优光滑化估计与迹定理综述（英文）

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数学进展 2016年第6期45卷 801-816页

作者： neal Bez 杉本充埼玉大学大学院理工学研究科数理电子情报部门名古屋大学大学院多元数理科学研究科

本文对自由薛定谔方程解的一大类光滑化估计中最优常数和最优函数存在性问题、以及其对偶估计式的迹定理问题近年来的研究进展进行综述.在我们近期的研究成果(含部分与町原秀二和斋藤洋树合作的成果)之前,除***和渡边一雄对部分特例得... 详细信息

本文对自由薛定谔方程解的一大类光滑化估计中最优常数和最优函数存在性问题、以及其对偶估计式的迹定理问题近年来的研究进展进行综述.在我们近期的研究成果(含部分与町原秀二和斋藤洋树合作的成果)之前,除***和渡边一雄对部分特例得到的结果之外,关于此问题的结果很有限.基于***在更一般情况下的结果、以及我们在同一研究脉络下对经典调和分析中Funk-Hecke定理的创新应用,我们现在可以对最优常数相关的大量自然问题给出解答;本综述中介绍了前述研究成果,并阐述了证明背后的主要思路.本文还提及这一问题与带漂移项的薛定谔方程中初值问题适定性相关的沟沺—竹内猜想之间的联系,并提出一些公开问题.

关键词：光滑化估计迹定理最优常数最优函数

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Spectrum of imaging and characteristics for liver tumors treated with irreversible electroporation

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Journal of Biomedical Science and Engineering 2012年第12期5卷 813-818页

作者： robert E. neal II Wa Cheung Helen Kavnoudias Kenneth r. Thomson Department of radiology The Alfred Hospital Melbourne Australia Departments of radiology and Surgery The Alfred Hospital Melbourne Australia

Therapeutic irreversible electroporation (IrE) is a relatively new technique for targeted tumor ablation. Needle electrodes are placed into or around the targeted region to deliver a series of brief electric pulses that disrupt cell membrane integrity, killing cells in a non-thermal manner that does not affect the extracellular matrix or sensitive structures such as major vasculature and bile ducts;making IrE an advantageous technique, especially for tumors that are unresectable or ineligible for thermal ablation. Here, we present on the imaging findings from IrE liver tumor treatments from ultrasound, computed tomography, magnetic resonance, and positron emission tomography. Imaging aids planning and implementing treatments by visualizing the targeted volume and guiding electrode placement. Immediate changes to the affected IrE region may be observed to verify complete ablation of the tumor with margin during the procedure, and permits follow-up evaluation of clinical outcome. In particular, we present tumor treatments in regions adjacent to sensitive structures that contraindicate thermal therapies.

关键词： IrE Pictorial review Non-Thermal Focal Ablation Minimally Invasive Surgery Medical Imaging

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An Improved Method for the Fitting and Prediction of the Number of COVID-19 Confirmed Cases Based on LSTM

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Computers, Materials & Continua 2020年第9期64卷 1473-1490页

作者： Bingjie Yan Jun Wang Zhen Zhang Xiangyan Tang Yize Zhou Guopeng Zheng Qi Zou Yao Lu Boyi Liu Wenxuan Tu neal Xiong School of Computer Science and Cyberspace Security Hainan UniversityHaikou570228China College of Humanities and Communication Hainan UniversityHaikou570228China University of Chinese Academy of Science Beijing100049China National University of Defense Technology Changsha410073China Department of Mathematics and Computer Science Northeastern State UniversityTahlequahUSA

New coronavirus disease(COVID-19)has constituted a global pandemic and has spread to most countries and regions in the *** understanding the development trend of confirmed cases in a region,the government can control the pandemic by using the corresponding ***,the common traditional mathematical differential equations and population prediction models have limitations for time series population prediction,and even have large estimation *** address this issue,we propose an improved method for predicting confirmed cases based on LSTM(Long-Short Term Memory)neural *** work compares the deviation between the experimental results of the improved LSTM prediction model and the digital prediction models(such as Logistic and Hill equations)with the real data as ***,this work uses the goodness of fitting to evaluate the fitting effect of the *** show that the proposed approach has a smaller prediction deviation and a better fitting *** with the previous forecasting methods,the contributions of our proposed improvement methods are mainly in the following aspects:1)we have fully considered the spatiotemporal characteristics of the data,rather than single standardized data.2)the improved parameter settings and evaluation indicators are more accurate for fitting and forecasting.3)we consider the impact of the epidemic stage and conduct reasonable data processing for different stage.

关键词： COVID-19 LSTM model predictive analysis

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Colorectal cancer screening: Opportunities to improve uptake, outcomes, and disparities

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World Journal of Gastrointestinal Endoscopy 2016年第20期8卷 733-740页

作者： neal Shahidi Winson Y Cheung Division of Gastroenterology Department of Medicine University of British Columbia Vancouver BC V6Z 2K5 Canada Division of Medical Oncology Department of Medicine University of British Columbia Vancouver BC V5Z 4E6 Canada British Columbia Cancer Agency VancouverBC V5Z 4E6 Canada

Colorectal cancer screening has become a standard of care in industrialized nations for those 50 to 75 years of age,along with selected high-risk *** colorectal cancer screening has been shown to reduce both the incidence and mortality of colorectal cancer,it is a complex multi-disciplinary process with a number of important steps that require optimization before tangible improvements in outcomes are *** both opportunistic and programmatic colorectal cancer screening,poor participant uptake remains an ongoing ***,current screening modalities(such as the guaiac based fecal occult blood test,fecal immunochemical test and colonoscopy) may be used or performed suboptimally,which can lead to missed neoplastic lesions and unnecessary endoscopic *** latter poses the risk of adverse events,such as perforation and post-polypectomy bleeding,as well as financial impacts to the healthcare ***,ongoing disparities in colorectal cancer screening persist among marginalized populations,including specific ethnic minorities(African Americans,Hispanics,Asians,Indigenous groups),immigrants,and those who are economically *** this context,we aimed to review the current literature on these important areas pertaining to colorectal cancer screening,particularly focusing on the guaiac based fecal occult blood test,the fecal immunochemical test and colonoscopy.

关键词： Fecal occult blood test Fecal immunochemical test Colonoscopy Neoplasia Polyp

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Determination and Quantification of Susceptibility of Heritance resistance to root rot of Eight Commercial Genotypes of Maize (Zea mays L.)

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Agricultural Sciences 2023年第5期14卷 665-684页

作者： Lazaro José Quintas neal Walker McLaren Free State University Blofoontein and Crops Research Institute Potchefstroom South Africa Grain Crops research Institute Potchefstroom South Africa

Maize is susceptible to a number of diseases that can infect all plant organs and serve as a constraint on cereal production. The reduction in cereal production caused by disease is estimated at an average of 9.4%. Corn root rot contributes greatly to the reduction in grain production and quality. The main objective of this work was to review the research on root rot in maize to determine the susceptibility of genotypes to root rot and to quantify the inheritance of resistance to root rot in maize. The methodology used was a complete 8 × 8 diallel design planted during the year 1999/2000. root discoloration, plant length, root volume, effective volume and yield were the evaluated parameters. To analyze the data and determine the combinatorial abilities, genetic correlations, heritability and correlated response, diallel analysis was used. Eight parental lines;P28, I137TN, MP706, E739, MO17, B37, B73, and B14 were planted. The lines were crossed into each other, all combinations according to the complete diallel model (Model 1). The F1 was harvested after maturation. For statistical analysis, the version of the Agrobase program (2016) was used. results show that F1 hybrids showed significant differences in root rot discoloration, plant height, root volume, effective root volume and yield. The P28 line and the B73XE739 cross had, respectively, the highest general and specific combinations. root discoloration had the highest genetic correlation (rA = 0.47) with plant length. Broad and narrow heritability for root rot discoloration were, respectively, h2 = 0.81 and h2 = 0.51. root rot discoloration showed the highest correlated response (Cr = 0.14) on plant length.

关键词： Maize (Zea mays L.) Discoloration Inheritance Hybrid Inbreeds Lines

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Intensification of Ethylene Production from Naphtha via a redox Oxy-Cracking Scheme： Process Simulations and Analysis

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Engineering 2018年第5期4卷 714-721页

作者： Vasudev Pralhad Haribal Yun Chen Luke neal Fanxing Li Department of Chemical and Biomolecular Engineering North Carolina State University Raleigh NC 27695-7905 USA School of Chemistry and Chemical Engineering South China University of Technology Guangzhou 510640 China

Ethylene production by the thermal cracking of naphtha is an energy-intensive process （up to 40 GJ heat per tonne ethylene）, leading to significant formation of coke and nitrogen oxide （NOx）, along with 1,8- 2 kg of carbon dioxide （CO2） emission per kilogram of ethylene produced, We propose an alternative pro- cess for the redox oxy-cracking （rOC） of naphtha, In this two-step process, hydrogen （H2） from naphtha cracking is selectively comhusted by a redox catalyst with its lattice oxygen first, The redox catalyst is subsequently re-oxidized by air and releases heat, which is used to satisfy the heat requirement for the cracking reactions, This intensified process reduces parasitic energy consumption and CO2 and NOx emissions, Moreover, the formation of ethylene and propylene can he enhanced due to the selective com-bustion of H2, In this study, the rOC process is simulated with ASPEN Plus^r based on experimental data from recently developed redox catalysts, Compared with traditional naphtha cracking, the rOC process can provide up to 52% reduction in energy consumption and CO2 emissions, The upstream section of the process consumes approximately 67% less energy while producing 28% more ethylene and propylene for every kilogram of naphtha feedstock,

关键词： Ethylene Naphtha cracking Process intensification Chemical looping Process simulations

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