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Genetic diseases conferring resistance to infectious diseases

Genes & Diseases 2015年第3期2卷 247-254页

作者： Isabelle c.Withrock Stephen J.Anderson Matthew A.Jefferson Garrett R.Mccormack Gregory S.A.Mlynarczyk Aron Nakama Jennifer K.Lange carrie A.Berg Sreemoyee Acharya Matthew L.Stock Melissa S.Lind K.c.Luna naveen c.kondru Sireesha Manne Bhavika B.Patel Bierlein Mde la Rosa Kuei-Pin Huang Shaunik Sharma Hilary Z.Hu Sri Harsha Kanuri Steve A.carlson Department of Biomedical Sciences Iowa State University College of Veterinary MedicineAmesIA 50011USA Department of Psychology Iowa State University College of Liberal Arts and SciencesAmesIA 50011USA Department of Kinesiology Iowa State University College of Liberal Arts and SciencesAmesIA 50011USA Department of Genetics Developmental and Cell BiologyIowa State University College of Liberal Arts and SciencesAmesIA 50011USA Neuroscience Interdepartmental Program Iowa State UniversityAmesIA 50011USA

This review considers available evidence for mechanisms of conferred adaptive advantages in the face of specific infectious *** short,we explore a number of genetic conditions,which carry some benefits in adverse circumstances including exposure to infectious *** examples discussed are conditions known to result in resistance to a specific infectious disease,or have been proposed as being associated with resistance to various infectious *** infectious diseasedgenetic disorder pairings include malaria and hemoglobinopathies,cholera and cystic fibrosis,tuberculosis and Tay-Sachs disease,mycotic abortions and phenylketonuria,infection by enveloped viruses and disorders of glycosylation,infection by filoviruses and NiemannePick c1 disease,as well as rabies and myasthenia *** also discuss two genetic conditions that lead to infectious disease hypersusceptibility,although we did not cover the large number of immunologic defects leading to infectious disease *** of the resistance-associated pairings(malaria/hemogloginopathies,cholera/cystic fibrosis,tuberculosis/Tay-Sachs,and mycotic abortions/phenylketonuria)appear to be a result of selection pressures in geographic regions in which the specific infectious agent is *** other pairings do not appear to be based on selection pressure and instead may be ***,research investigating these relationships may lead to treatment options for the aforementioned diseases by exploiting established mechanisms between genetically affected cells and infectious *** may prove invaluable as a starting point for research in the case of diseases that currently have no reliably curative treatments,e.g.,HIV,rabies,and Ebola.

关键词： Disease Infectious Pathogen Polymorphism Resistance Susceptibility

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cool white light and tunable multicolor emission from Tb^(3+)/Dy^(3+)co-activated glasses under different excitations for WLEDs

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Journal of Rare Earths 2024年第1期42卷 46-56,I0002页

作者： L.Vijayalakshmi K.naveen Kumar Jong Dae Baek Department of Automotive Engineering Yeungnam UniversityGyeongsanGyeongbuk38541Republic of Korea Department of Mechanical Engineering Yeungnam UniversityGyeongsan38541Republic of Korea

A set of co-doped(Tb^(3+)/Dy^(3+))lithium zinc borate(LZB)glasses were developed by melt *** structural evaluation was performed for synthesized glassy *** Dy^(3+)and Tb^(3+)individually doped glasses exhibit intense yellow and green luminescence bands at 575 nm(^(4)F_(9/2)→^(6)H_(13/2))and543 nm(^(5)D_(4)→^(7)F_(5)),*** sensitization effect of Dy^(3+)on Tb^(3+)was analyzed by increasing the Tb^(3+)content with respect to the optimum Dy^(3+)content(0.5 mol%)in Dy^(3+)/Tb^(3+).The spectral overlay of Dy^(3+)luminescence and Tb^(3+)absorption profiles,Dy^(3+)/Tb^(3+)PL spectra under different excitations 352,362,376,and 385 nm,shortening decay lifetimes of Dy^(3+)in Dy^(3+)/Tb^(3+)co-activated glasses,energy transfer(ET)parameters,chromaticity coordinates and their corresponding correlated temperatures all help to explain ET from Dy^(3+)to Tb^(3+).At 385 nm of Dy^(3+)excitation,the optimized co-activated(0.5Dy^(3+)+1.0Tb^(3+)):LZB glass displays cool white light *** non-radiative ET from Dy^(3+)to Tb^(3+)is dominated by electric dipole-dipole interaction and its ET efficiency was calculated to be 63%.At the same time,reverse ET from Tb^(3+)to Dy^(3+)was also *** shift in color coordinates from dominant yellow to greenish-yellow,green and white light emission suggests that Dy^(3+)/Tb^(3+)coactivated LZB glasses can be a potential candidate for UV converted multicolor and white light emitting devices.

关键词： Rare earths Photoluminescence Energy transfer Spectral overlap Decay lifetime Multicolor emitting LEDs

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Micro grid for All India Institute of Medical Sciences,Madurai

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clean Energy 2021年第2期5卷 254-272页

作者： c.Palanichamy P.naveen Multimedia University 63100 CyberjayaMalaysia

In 2018,the Government of India approved the establishment of the New All India Institute of Medical Sciences(AIIMS)in Thoppur,Madurai,Tamil Nadu,*** the most important amenity for continuing primary care and rescue response is a healthcare facility,a secure electricity supply becomes an imperative ***,as the energy supplier for the new AIIMS,Madurai,this paper proposes a microgrid combined with the utility *** microgrid consists of a 4-MW photovoltaic system,a 1.8-MW wind-turbine energy-conversion system,a backup diesel generator capable of meeting the forecasted maximum demand and a 1-MW battery energy-storage *** AIIMS Microgrid will have a service providing a capacity of 20 MVA following integration with the utility *** proposed microgrid would be the first attempt at healthcare facilities in India since its first day of work to ensure the availability of *** would have a 9.8%return on investment,a 13.6%internal rate of return and a payback period of 6.75 years once it is operational,as well as an attractive levelized cost of energy(LcOE)of USD 0.07547/*** would provide an environmentally friendly atmosphere by avoiding an annual emission of 6261132 kg of carbon dioxide,27362 kg of sulphur dioxide and 12838 kg of nitrogen oxides as compared to power supplied entirely from the utility grid.

关键词： new healthcare facilities load assessment microgrid proposal optimization

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construction of high-pressure adsorption isotherm:A tool for predicting coalbed methane recovery from Jharia coalfield,India

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International Journal of Mining Science and Technology 2019年第5期29卷 765-769页

作者： Mohammad Asif D.c.Panigrahi Paul naveen Keka Ojha Department of Mining Engineering Indian Institute of Technology(ISM)Dhanbad 826004India Department of Petroleum Engineering Indian Institute of Technology(ISM)Dhanbad 826004India

Adsorption isotherm relates the gas storage capacity as a function of pressure at constant *** this paper,adsorption isotherm of two dry borehole samples was constructed in the laboratory using the manometric *** was measured for two gases,i.e.,cH4 and cO2 to pressure up to 8.4 *** the construction of sorption isotherm,coal was characterized by proximate,ultimate and petrographic *** gas content of these two samples was found 2.29 m3/t and 2.75 m3/*** images were obtained for the pore size distribution of coal using pore image *** of coalbed methane recovery from cH4 adsorption isotherm showed that these coalbeds are under ***2 isotherm was constructed to estimate enhanced coalbed methane(EcBM)*** wise cO2/cH4 sorption ratio was found 2.09 times to 2.75 times *** paper presents the interpretation of isotherm data to find the recovery factor of methane production from Jharia coalfield.

关键词： coalbed methane Adsorption isotherm Pore image analysis Gas content Jharia coalfield

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Influence of temperature dependent heat source/sink on transient MHD free convective flow in an infinite rigid impermeable vertical cylinder with chemical reaction

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Propulsion and Power Research 2023年第4期12卷 568-583页

作者： naveen Dwivedi Ashok Kumar Singh Nirmal c.Sacheti Department of Mathematics Institute of ScienceBanaras Hindu UniversityVaranasi 221005India Department of Mathematics Sahu Jain CollegeNajibabadAffiliated to M.J.P.Rohilkhand UniversityBareilly 246763India Retired Professor Department of MathematicsCollege of ScienceSultan Qaboos UniversityAl Khod PC 123MuscatSultanate of Oman

It is increasingly apparent that the inclusion of mass transfer aspects,together with certain thermal conditions,in the momentum and energy equations governing MHD flows leads to a numbers of real life *** this in view,we have attempted an exact analysis of heat and mass transfer aspects in transient hydromagnetic free convective flow of an incompressible viscous fluid through a vertical pipe under an externally applied magnetic field,assuming presence of chemical reaction and heat source/*** governing PDEs,which simplify to a set of 3 linear ODEs in the physical set up considered here,have been solved using Laplace transform technique,with solutions for key physical variables presented in the term of Bessel and modified Bessel *** influence of governing non-dimensional parameters,namely,Hartmann number,Schmidt number,source/sink parameter,Prandtl number and chemical reaction parameter,has been illustrated on the developing velocity and some concentration *** important quantities of engineering interest-surface skin friction and volumetric flow rates-have been computed too and *** notable finding worth mentioning are:(a)heat source presence causes higher fluid velocity as compared to the heat sink;(b)all important surface shear stress can be suitably controlled,among others,by chemical reaction parameter and Schmidt *** key challenge of this study has been to obtain exact closed-form solutions of the field equations,including cumbersome Laplace *** study finds innovative applications in the emerging fields such as magnetic materials processing,chemical processes,solar energy systems,etc.

关键词： circular cylinder Hydromagnetic transient flow chemical reaction Source/sink Free convection

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A microgrid for the secluded Paana Theertham Kani settlement in India

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clean Energy 2022年第1期6卷 43-58页

作者： c.Palanichamy Tan Woan Wen P.naveen Multimedia University 63100 CyberjayaMalaysia

Recognizing the importance of electricity as a driver of rapid economic growth and poverty alleviation,India aims to provide access to all households by *** the best efforts of state and federal governments to meet consumers’electrical needs,budget constraints,inefficient operations and massive loan burdens have hampered their *** from these concerns,rural India,which accounts for 65%of the population,is plagued by a slew of issues,including low electricity demand,a low load factor and the expectation of cheap *** concerns bind the authorities’hands,preventing them from moving *** a result,this project aims to model an autonomous microgrid system that integrates three potential renewable-energy systems,namely wind,sun and hydrokinetic,to provide electricity for a remote *** starts with assessing the region’s electricity needs with its *** HOMER Pro platform creates a cost-effective microgrid based on the demand *** components of the microgrid include 6.4-kW small wind turbine(SWT)groups,4.4-kW solar photovoltaic(PV)panels,a 5-kW hydrokinetic water turbine,battery storage and a *** project is unique in that it considers site-specific initial capital costs,replacement costs,and operation and maintenance costs of the renewable-energy systems,and it does not include any environmentally hazardous energy *** successful optimization results in terms of levelized energy costs are$0.0538,$0.0614 and$0.0427/kWh for wind,solar and hydrokinetic components,respectively,without any environmental issues.

关键词： secluded society electrification microgrid renewables distributed generation

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Effect of Fuel to Oxidant Molar Ratio on Structural and Dc Electrical conductivity of ZnO Nanoparticles Prepared by Simple Solution combustion Method

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Journal of Materials Science & Technology 2013年第10期29卷 898-902页

作者： c.S.naveen M.L.Dinesha H.S.Jayanna Department of PG Studies and Research in Physics Kuvempu University

ZnO nanoparticles of different sizes were prepared by varying the molar ratio of glycine and zinc nitrate hexahydrate as fuel and oxidizer （0.1, 0.8, 1.11, 1.3, 1.5, 1.7, 2.0） by simple solution combustion method. UV-Visible spectrophotometry studies show that, the band gap of the prepared ZnO nanoparticles increases with increasing fuel to oxidant （F/O） molar ratio up to 1.7 revealing the formation of ZnO nanoparticles. The decrease in band gap for the sample of F/O molar ratio 2.0 is due to an increase in particle size. Powder X-ray diffraction patterns of the prepared samples show the formation of single phase ZnO nanoparticles and the particle size decreases with increasing F/O molar ratio up to 1.7. Surface morphology of the prepared samples was studied by scanning electron microscopy and it was observed that, the porosity increases with increasing F/O molar ratio. Dc electrical conductivity at room temperature and in the temperature range of 303-563 K was studied for all the samples and the results revealed that, the sample of F/O molar ratio 1.7 has low electrical conductivity at room temperature and high EAR （high temperature activation energy） compared to other samples.

关键词： ZnO nanoparticles Structural characterization Electrical conductivity

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Significance of Stefan blowing effect on flow and heat transfer of casson nanofluid over a moving thin needle

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communications in Theoretical Physics 2021年第9期73卷 51-58页

作者： A M Jyothi R naveen Kumar R J Punith Gowda B c Prasannakumara Bangalore Institute of Technology BangaloreIndia Department of Studies and Research in Mathematics Davangere UniversityDavangere-577002KarnatakaIndia

The current mathematical model explains the influence of non-linear thermal radiation on the casson liquid flow over a moving thin needle by considering Buongiorno’s nanofluid *** influences of Stefan blowing,Dufour and Soret effects are also considered in the *** equations which represent the described flow pattern are reduced to ordinary differential equations(ODEs)by using apt similarity transformations and then they are numerically solved with Runge–Kutta-Fehlberg’s fourth fifth-order method(RKF-45)with shooting *** impacts of pertinent parameters on thermal,mass and velocity curves are deliberated *** friction,rate of heat and mass transfer are also discussed *** reveal that,the increase in values of Brownian motion,thermophoresis,Dufour number,heating and radiative parameters improves the heat *** increasing values of the Schmidt number deteriorates the mass transfer but a converse trend is seen for increasing values of the Soret ***,the escalating values of the radiative parameter decays the rate of heat transfer.

关键词： moving thin needle Brownian motion and thermophoretic diffusion non-linear thermal radiation Stefan blowing condition

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Magnetohydrodynamic flow and heat transfer of a hybrid nanofluid over a rotating disk by considering Arrhenius energy

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communications in Theoretical Physics 2021年第4期73卷 9-20页

作者： M Gnaneswara Reddy naveen Kumar R B c Prasannakumara N G Rudraswamy K Ganesh Kumar Department of Mathematics Acharya Nagarjuna University CampusOngole-523001India Department of Studies and Research in Mathematics Davangere UniversityShivagangothriDavangere-577007KarnatakaIndia Department of Mathematics P.C.Jabin Science CollageHubballi-580031India

This research work explores the effect of hybrid nanoparticles on the flow over a rotating disk by using an activation energy ***,we considered molybdenum disulfide and ferro sulfate as nanoparticles suspended in base fluid *** magnetic field is pragmatic normal to the hybrid nanofluid flow *** derived nonlinear ordinary differential equations are non-dimensionalized and worked out numerically with the help of Maple software by the RKF-45 *** scientific results for a non-dimensionalized equation are presented for both nanoparticle and hybrid nanoparticle *** of various predominant restrictions on flow and thermal fields are *** estimation for friction factor,local Nusselt number and Sherwood number are also *** reveal that the reduction of the heat transfer rate is greater in hybrid nanoparticles when compared to nanoparticles for increasing values of Eckert Number and the thermal field enhances for the enhanced values of volume fraction.

关键词： porous medium MHD hybrid nanoparticles activation energy

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A comparative analysis of paddy crop biotic stress classification using pre-trained deep neural networks

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Artificial Intelligence in Agriculture 2022年第1期6卷 167-175页

作者： naveen N.Malvade Rajesh Yakkundimath Girish Saunshi Mahantesh c.Elemmi Parashuram Baraki Department of Information Science and Engineering Smt.Kamala and Sri.Venkappa M.Agadi College of Engineering and TechnologyLakshmeshwar582116KarnatakaIndia Department of computer Science and Engineering K.L.E.Institute of TechnologyHubballi580030KarnatakaIndia Department of computer Science and Engineering Navkis College of EngineeringHassan573217KarnatakaIndia Department of computer Science and Engineering Smt.Kamala and Sri.Venkappa M.Agadi College of Engineering and TechnologyLakshmeshwar582116KarnatakaIndia Visvesvaraya Technological University Belagavi 590018KarnatakaIndia

The agriculture sector is no exception to the widespread usage of deep learning tools and *** this paper,an automated detection method on the basis of pre-trained convolutional Neural Network(cNN)models is proposed to identify and classify paddy crop biotic stresses from the field *** proposed work also provides the empirical comparison among the leading cNN models with transfer learning from the ImageNet weights namely,Inception-V3,VGG-16,ResNet-50,DenseNet-121 and *** spot,hispa,and leaf blast,three of the most common and destructive paddy crop biotic stresses that occur during the flowering and ripening growth stages are considered for the *** experimental results reveal that the ResNet-50 model achieves the highest average paddy crop stress classification accuracy of 92.61%outperforming the other considered cNN *** study explores the feasibility of cNN models for the paddy crop stress identification as well as the applicability of automated methods to non-experts.

关键词： Paddy crop Stress classification Biotic stress PlantVillage ImageNet Pre-trained cNN models

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