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Comparative assessment of clinical profile and outcomes after primary percutaneous coronary intervention in young patients with single vs multivessel disease

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World Journal of Cardiology 2020年第4期12卷 136-143页

作者： Atif Sher Muhammad Tariq Ashraf Ayaz Mir Syed Alishan Faiza Farooq Ali Ammar Musa Karim Syed Nadeem Hassan Rizvi Tahir Saghir Jawaid Akbar Sial naveed Ullah Khan Department of Adult Cardiology National Institute of Cardiovascular DiseasesKarachi 75510Pakistan Department of Clinical Research National Institute of Cardiovascular DiseasesKarachi 75510Pakistan

BACKGROUND Even though percutaneous coronary intervention(PCI)improved the survival of patients with acute myocardial infarction,still multivessel coronary artery disease remains an important factor burdening prognosis and it is being associated with a worse prognosis compared to single-vessel disease(SVD).AIM To compare the clinical profile and outcomes after the primary PCI in young patients with SVD vs multivessel disease(MVD).METHODS The retrospective cohort of patients were divided into two groups:SVD and MVD *** study population consisted of both male and female young(≤45 years)patients presented with ST-elevation myocardial infarction(STEMI)at the National Institute of Cardiovascular Disease,Karachi,Pakistan and undergone primary PCI from 1 st July 2017 to 31 st March *** and postprocedure management of the patients was as per the guidelines and institutional *** A total of 571 patients with STEMI,≤45 years were stratified into two groups by the number of vessels involved,342(59.9%)with SVD and 229(40.1%)with *** average age of these patients was 39.04±4.86 years.A lower prevalence of hypertension and diabetes was observed in SVD as compare to MVD group(25.1%vs 38%,P<0.01;11.7%vs 27.5%,P<0.001)***,smoking was more prevalent among the SVD group as compare to MVD group(36.3%vs 28.4%,P=0.05).The high-C Lesion was observed in a significantly higher number of younger patients with MVD as compared to SVD group(48.8%vs 39.2%,P=0.021).Post-procedure thrombolysis in myocardial infarction flow grade was found to be not associated with the number of diseased vessels with a P value of 0.426 and thrombolysis in myocardial infarction flow grade III was observed in 98%vs 96.5%of the patients is SVD vs MVD *** The MVD comprised of around 40%of the young patients presented with ***,this study shows that diabetes and hypertension have a certain role in the pathogenesis of multivessel diseases,therefore,preventive

关键词： Young Multivessel disease Primary percutaneous coronary intervention STelevation myocardial infarction Premature coronary artery diseases Single-vessel disease

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Side Effects of Chemotherapy in Cancer Patients and Evaluation of Patients Opinion about Starvation Based Differential Chemotherapy

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Journal of Cancer Therapy 2014年第8期5卷 817-822页

作者： Muhammad Shahbaz Aslam Sidra naveed Aftab Ahmed Zaigham Abbas Iram Gull Muhammad Amin Athar Department of Microbiology and Molecular Genetics University of the Punjab Lahore Pakistan Institute of Biochemistry & Biotechnology University of the Punjab Lahore Pakistan

Side-effects associated with the cancer chemotherapy limit the scope of chemotherapeutic drugs and no data was available about these side effects in Pakistan. Moreover starvation based differential chemotherapy has been proved to greatly reduce the side effects of chemotherapy depending on starvation time. The current study was conducted to survey the common side effects of the chemotherapeutic drugs and the role of starvation to reduce them. The study included total 100 subjects with multiple carcinomas. A comprehensive questionnaire about starvation inquiry, chemotherapy side effects and their basic information was filled by interviewers as told by patients. There were 48% patients with breast cancer and 11% with uterine cancer. Out of these patients 30%, 28%, 9% and 9% patients were agreed to starve for 12, 24, 36 and 48 hours respectively. The survey regarding the side effects of chemotherapy showed that 43% patients were suffering from headache, fatigue 90%, weakness 95%, hair loss 76%, nausea 77%, vomiting 75%, diarrhea 31%, abdominal cramps 40%, mouth sores 47%, dry mouth 74%, memory impairment 14%?and numbness 49%. Breast cancer is the most common cancer in Pakistan. Only 18% of the total patients were agreed to starve for more than one day. Chemotherapy-associated side effects vary greatly and it does not depend upon cancer type. But these side effects depend on multiple factors such as the type and dose of chemotherapeutic drug, patient’s health status and stage of cancer.

关键词： Starvation Differential Chemotherapy Side Effects Chemotherapeutic Drugs

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以猪小肠黏膜提取物作为α-葡萄糖苷酶和二肽基肽酶Ⅳ的酶活力分析体系的建立

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食品科学 2019年第23期40卷 44-51页

作者：甲承立 naveed HUSSAIN 董洁王芬李函彤张书文芦晶逄晓阳刘鹭吕加平中国农业科学院农产品加工研究所农业农村部农产品加工重点实验室北京100093 山西农业大学食品科学与工程学院山西晋中030800 天津科技大学食品工程与生物技术学院天津300457 北京市营养源研究所系统营养工程技术研究中心北京100069

α-葡萄糖苷酶和二肽基肽酶IV(dipeptidyl peptidase 4,DPP-4)是II型糖尿病治疗中2种重要的靶向酶。这两种商品化酶价格昂贵且主要来源于微生物,难以有效用于两种酶抑制剂的筛选,而这两种酶均普遍存在哺乳动物的小肠中。为了获得经济有... 详细信息

α-葡萄糖苷酶和二肽基肽酶IV(dipeptidyl peptidase 4,DPP-4)是II型糖尿病治疗中2种重要的靶向酶。这两种商品化酶价格昂贵且主要来源于微生物,难以有效用于两种酶抑制剂的筛选,而这两种酶均普遍存在哺乳动物的小肠中。为了获得经济有效、来源于哺乳动物体内的α-葡萄糖苷酶和DPP-4,本研究收集新鲜的猪小肠黏膜分泌物及上皮细胞,对比分析了猪小肠不同部位黏膜提取物的α-葡萄糖苷酶和DPP-4的活力。以猪小肠黏膜提取物作为α-葡萄糖苷酶和DPP-4的酶反应体系,并且利用这两种酶的阳性药(阿卡波糖和抑二肽素A(diprotin A,IPI))分别进行了抑制率验证和评价。阿卡波糖对商品和猪回肠源α-葡萄糖苷酶的半数有效抑制质量浓度(median inhibition concentration,IC50)分别是1.1024、0.2447 mg/mL;IPI对商品和猪回肠源DPP-4的IC50分别为19.1197、41.2684μg/mL。通过比较发现,猪回肠黏膜提取物的α-葡萄糖苷酶和DPP-4比活力分别为0.0841、0.0534 U/mg,在3种黏膜提取物中均为最高,因此选择猪回肠黏膜提取物作为商品化α-葡萄糖苷酶和DPP-4的替代物进行抑制剂的筛选。

关键词： α-葡萄糖苷酶二肽基肽酶IV(DPP-4) 猪小肠酶比活力

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任务型教学法在美国学习者汉语口语教学中的应用

任务型教学法在美国学习者汉语口语教学中的应用

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作者：王天赋（naveed M Heravi）中央民族大学

学位级别：硕士

近年来,越来越多的美国学生开始学习中文。然而,这还只是一个新的趋势,美国的汉语教学还处于一个初级阶段,有着很大的提升空间。在这种情况下采用一种更为适合美国汉语学习者的教学方法就显得尤为重要。通常美国学生将口语视为汉语学习... 详细信息

近年来,越来越多的美国学生开始学习中文。然而,这还只是一个新的趋势,美国的汉语教学还处于一个初级阶段,有着很大的提升空间。在这种情况下采用一种更为适合美国汉语学习者的教学方法就显得尤为重要。通常美国学生将口语视为汉语学习中必须掌握的技能之一,但是对声调以及汉语结构的正确掌握是大部分美国学生所共同面临的难题。尽管他们非常想要努力提高自己的口语水平,同时相较其他国家的学生而言,美国学生的个性更外向且乐于沟通,但是在口语学习中所遭遇的这些困难减缓了他们的学习进度,特别是对于那些刚从美国到中国来的学生,这部分学生在美国所接受过的汉语教学方式显然还没能有效的解决上述问题。作为一名美国留学生,笔者开始关注在口语教学中采用怎样的教学方法会更适合美国学生。本论文首先对美国汉语教学的特点进行了简单分析：它与中国的对外汉语教学之间最大的差别在于没有专门的口语课。本文还会提及美国学生的普遍特点及其学习习惯：他们更擅长且愿意表达自我,喜欢互动性强的活动并且对口语交流方面的课程更感兴趣。同时,本文也会对中美之间的汉语口语教学进行比较。本文在此基础上继续分析和探讨任务型教学法在对美国学生汉语口语教学中的应用及其在流利度、准确度和语言复杂度方面的影响。总的说来,任务型教学法是一种教师通过指导学生进行和完成已制定好的课堂任务的教学方式。该教学法的主旨在于执行和完成教师为达成某个特定教学目标所设计的“任务”。这种教学法可以被分为广义任务型教学法和狭义任务型教学法两种,也有语言学家将此教学法按其实施过程分为三个步骤,即：任务前、任务中和语言焦点(也被称为任务后)。此外,任务型教学法也可根据其任务形式的不同分成八种不同的任务类型。文中也会给出一些具体的范例,用以说明如何设计课程且在课堂上实施该教学法,从而达到有效提高学生口语水平的教学目的。本文还包括有一个专门针对在华学习汉语的美国学生的问卷调查,其调查结果有助于说明在中国的对外汉语口语教学中任务型教学法所开展的情况和美国学生对于该教学法持怎样的态度和反馈,以及他们觉得该教学法在其汉语口语技能方面起到了怎样的作用。调查结果表明任务型教学法不但为美国学生所接受,更为重要的是,他们确实相信这是一种能够有效帮助他们提高口语技能的教学方式。综上所述,本文在探讨美国汉语教学的情况以及美国学生特点的基础上,结合任务型教学法的理论,讨论如何运用该教学法解决在针对美国学生汉语口语教学中的问题,从而证明了任务型教学法是一种非常适用于美国学生的、有效的汉语口语教学法。

关键词：汉语口语任务型教学法美国学生

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Regulation of the order-disorder phase transition in a Cs_(2)NaFeCl_(6) double perovskite towards reversible thermochromic application

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Journal of Semiconductors 2021年第7期42卷 44-57页

作者： Wenzhe Li naveed Ur Rahman Yeming Xian Hang Yin Yunkai Bao Yi Long Songyang Yuan Yangyi Zhang Yaxuan Yuan Jiandong Fan Institute of New Energy Technology Department of Electronic Science and EngineeringCollege of Information Science and TechnologyJinan UniversityGuangzhou 510632China

Multifunctional lead-free double perovskites demonstrate remarkable potential towards applications in various ***,an environmentally-friendly,low-cost,high-throughput Cs_(2)NaFeCl_(6) single crystal with exceedingly high thermal stability is designed and *** obtains a cubic lattice system in the temperature range of 80-500 K,accompanied by a completely reversible chromatic variation ranging from yellow to ***,the intriguing thermochromism is proved to own extremely high reproducibility(over 1000 cycles)without a hysteretic effect,originating from its structural flexibility that including(i)the noteworthy distortion/deformation of[NaCl_(6)]5−and[FeCl_(6)]3−octahedra;(ii)order-disorder arrangement transition of[NaCl_(6)]5−and[FeCl6]3−octahedra as the function of *** study paves the way towards a new class of smart windows and camouflage coatings with an unprecedented colour range based on a Cs_(2)NaFeCl_(6) perovskite.

关键词： lead-free perovskite Cs_(2)NaFeCl_(6)single crystal thermochromism crystallographic structure order-disorder phase transition

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Trend Analysis of Three Major Mosquito Borne Diseases in Punjab, India

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Journal of Biosciences and Medicines 2020年第5期8卷 1-11页

作者： Gagandeep Singh Grover Jaspreet Takkar Taruna Kaura Seema Devi naveed Pervaiz Upninder Kaur Rakesh Sehgal National Vector Borne Disease Control Programme Chandigarh Punjab India Department of Physiology Gian Sagar Medical College Punjab India Department of Medical Parasitology PGIMER Chandigarh India Department of Zoology Panjab University Chandigarh India

Background & Objectives: Understanding the distribution and prevalence of three major mosquito borne diseases in an area is critical for the development of effective vector control strategies and public health interventions. The present study is therefore aimed to explore the epidemiological trend of malaria, dengue and chikungunya from 2012 to 2018 in Punjab. Methods: Quantitatively retrospective data was collected from Department of Health and Family Welfare, the National Vector Borne Disease Control Programme (NVBDCP), Punjab from 2012 to March 2018. The collected data was statistically analysed. Results: In case of malaria highest prevalent districts in Punjab are Mansa and Bathinda, for dengue Patiala, Ludhiana and S.A.S. Nagar and Patiala for chikungunya. Malaria was reported mainly from rural areas while dengue and chikungunya were found more in urban areas. For all three mosquito borne diseases, males were infected more as compared to females. Malaria cases were reported in months of August and September while dengue cases increased from July to November whereas chikungunya cases were highest in months of August to October. Conclusions: These findings help in concluding the trend analysis which in turn helps us to increase our focus on disease endemic districts along with boosting the vector control strategies in respective districts. Further the control of these mosquito borne diseases can be solved by employing adequate human resources, by increasing awareness in the community by conducting health camps and strengthening the entomological surveillance for timely reduction in the breeding of the vectors, especially before the repeated rise in cases during the period from July to November each year.

关键词： NVBDCP Malaria Dengue Chikungunya

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Characterization and Potential Evaluation of the Talhar Shale Gas Reservoir in the Lower Indus Basin, Pakistan

Characterization and Potential Evaluation of the Talhar Shal...

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2023年中国地球科学联合学术年会

作者： Muhammad Tahir Jamil Guozhong Gao Perveiz Khalid Shamshad Akhtar naveed Munawar

To assess the unconventional shale gas reservoir potential of the Lower Indus Basin, particularly the Talhar Shale of the Lower Goru formation, Pakistan, various techniques, including elastic, geomechanical, petrophysical, and mineralogical analyses, are used. The study emphasizes key parameters such as the total organic carbon (TOC) content, and volume of kerogen, as they play a vital role in determining the shale gas reservoir potential.

关键词： Characterization and Potential Evaluation of the Talhar Shale Gas Reservoir in the Lower Indus Basin Pakistan

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Investigation of Climate and Land Use Policy Change Impacts on Food Security in Eastern Sudan, Gadarif State

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Journal of Geographic Information System 2017年第5期9卷 546-557页

作者： Yousif Elnour Yagoub Zhongqin Li Omer Said Musa Muhammad naveed Anjum Feiteng Wang Zhang Bo State Key Laboratory of Cryospheric Sciences/Tian Shan Glaciological Station Northwest Institute of Eco-Environment and Resources CAS Lanzhou China Department of Forest Protection and Conservation University of Khartoum-Faculty of Forestry Shambat Sudan College of Geography and Environmental Science Northwest Normal University Lanzhou China Division of Hydrology Water-Land Resources Northwest Institute of Eco-Environment and Resources CAS Lanzhou China

The aims of this research were to investigate the impacts of climate variations on land use policies, food security and vegetation cover in Gadarif State (eastern Sudan) during 1961 to 2013. Analysis of precipitation and temperature time series revealed that the annual precipitation was decreasing while the temperature was increased in the study area. Precipitation was decreasing at a rate of −50.3 mm/10a, while the temperature was increasing at a rate of 0.02°C/10a. The result of both SPEI and SPI showed that the Gadarif State has been changed to a high frequency of drought during 1961-2013. Sorghum yield showed a significant positive relationship with precipitation during July and October (CC = 0.364 and 0.321, respectively), moreover, a significant positive relationship between Sesame yield and precipitation was observed during July (CC = 0.335). A significant negative relationship between Sorghum yield and mean temperature was observed during the rainy season (July to October) with CC = −0.278. The yield productivity of Sorghum and Sesame had decreased significantly (from more than 800 kg/ha in the 1960s to less than 200 kg/ha in 2000s for Sorghum, while 500 kg/ha in 1960s to 100 kg/ha in 2000s for Sesame). The Mechanized Rain-fed Agriculture (MRA) area of Sorghum and Sesame in the Gadarif State had been increased from 1,058,241 ha to 2,799,655 ha during 1961 to 2013. Thus, we ultimately suggest that in the Gadarif State, policy makers must strive for an increase in yield per unit area by using sufficient fertilizers along with the gradual increment in tendencies of grain production through expansion of the cultivated area.

关键词： Climate Change Land Use Policy Change Food Security Gadarif State

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智能水下机器人全局及局部路径规划技术研究

智能水下机器人全局及局部路径规划技术研究

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作者：哈泽尔（Khizer naveed）北京理工大学

学位级别：硕士

路径规划技术是智能水下机器人（Autonomous Underwater Vehicle,简称AUV）的关键技术之一,在一定程度上它标志着水下机器人智能水平的高低。路径规划的目的、不同的运动规划必须考虑动力学,是找到一个动的最优路径,用最少的时间以及完... 详细信息

路径规划技术是智能水下机器人（Autonomous Underwater Vehicle,简称AUV）的关键技术之一,在一定程度上它标志着水下机器人智能水平的高低。路径规划的目的、不同的运动规划必须考虑动力学,是找到一个动的最优路径,用最少的时间以及完全的环境模型。我们讨论了这些最成功的机器人三维路径规划算法的基本原理,近年来已经发展起来,集中在可应用于空中机器人、地面机器人和水下机器人的普遍适用的算法上。这论文对大范围海洋有流环境下智能水下机器人的路径规划技术进行了系统深入的研究,主要包括以下几个方面的内容:本文首先介绍了机器人以及智能水下机器人的发展情况,分析了智能水下机器人的国内外的研究动态和发展趋势,详细介绍了课题的背景和主要内容。其次简要介绍了机器人路径规划技术,包括路径规划的定义、分类、相关问题、几种典型的路径规划方法以及最新的研究动态等。在分析大范围海洋环境下路径规划的复杂性以及总结以前的路径规划算法的基础上,提出了一整套从全局到局部的路径规划算法。最后,本文分别详细介绍了全局路径规划和局部路径规划两个算法:基于分层模型的遗传模拟退火算法路径规划和基于雷达法的局部路径规划。包括算法的基本思想、算法实现中的几个关键技术等。本文还给出了两个算法的计算机仿真结果。

关键词：智能水下机器人(AUV) 路径规划分层模型遗传模拟退火算法雷达法

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Glacier Mass-Balance Variation in China during the Past Half Century

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Journal of Geoscience and Environment Protection 2018年第5期6卷 37-58页

作者： Yousif Elnour Yagoub Zhongqin Li Ahmed A. H. Siddig Omer Said Musa Muhammad naveed Anjum State Key Laboratory of Cryospheric Sciences/Tian Shan Glaciological Station Northwest Institute of Eco-Environment and Resources CAS Lanzhou China Faculty of Forestry Department of Forest Protection and Conservation University of Khartoum Shambat Sudan Division of Hydrology Water-Land Resources Northwest Institute of Eco-Environment and Resources CAS Lanzhou China

The aim of this study is to investigate the impact of temperature trend on glacier-mass balance, snow density, snowmelt, snow depth and runoff by using observations of nine glacier stations that covered most of the China over the period of 1979-2013. Trend analysis showed an increasing trend of temperature on all of the selected stations. On an average, temperature was increasing at the rate of 0.46/10a. The increasing trend of temperature showed a negative relationship with annual glacier-mass balance on most of the stations and caused a decrease in annual balance. Results of Pearson’s correlation analysis showed a highly significant negative correlation between temperature and snow density (correlation coefficient (CC = -0.661 at 0.01 significance level). There was a significant positive correlation between temperature and snowmelt (CC = 0.532 at 0.01 significance level). There was a significant negative correlation between temperature and snow depth (correlation coefficient (CC = -0.342 at 0.05 significance level). Moreover, there was a significant positive correlation between temperature and runoff (CC = 0.586 at 0.01 significance level). Increasing trend of temperature caused an increasing trend of annual snowmelt and runoff anomaly% at the rate of 24.82/10a and 9.87/10a, respectively. On the other hand, a declining trend in annual snow density and snow depth anomaly% was found at a rate of -5.32/10a and -1.93/10a, respectively. We concluded that the snow density, snowmelt and runoff are significantly sensitive to temperature in China. This contribution has provided information for further understanding of glacier variation and its influencing factors.

关键词： Glacier Mass-Balance Snow Density Snowmelt Snow Depth Runoff Climate Variation

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