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老年患者非心脏手术围手术期心血管风险评估和管理的中国专家共识(2023)

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中华老年医学杂志 2024年第8期43卷 937-953页

作者：国家老年医学中心中华医学会心血管病学分会心血管老年学组中华老年医学杂志编辑委员会中国心血管杂志编辑委员会季福绥于雪祖凌云贾娜刘巍孙艳霞不详北京医院心内科北京大学第三医院心内科北京积水潭医院心内科北京医院麻醉科

非心脏手术围术期并发症中以心血管并发症最为常见,在老年患者中尤为突出。老年患者在非心脏手术前进行心血管风险评估至关重要。国外指南提供了非心脏手术患者围手术期心血管风险评估及管理的推荐意见,但缺乏针对老年人群的具体意见。... 详细信息

非心脏手术围术期并发症中以心血管并发症最为常见,在老年患者中尤为突出。老年患者在非心脏手术前进行心血管风险评估至关重要。国外指南提供了非心脏手术患者围手术期心血管风险评估及管理的推荐意见,但缺乏针对老年人群的具体意见。本共识针对老年人群,在围手术期心血管风险评估和管理方面提出了具体问题,系统梳理了国内外相关证据,给出循证推荐意见,以期为临床工作者提供参考。

关键词：非心脏手术围手术期心血管风险老年人

GLOBAL CLIMATE CHANGES AND THE TOURISM OF CHINA

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Journal of Geographical Sciences 1996年第2期6卷 97-102页

作者： Ren Guoyu(national Climate center, Beijing 100081People’s Republic of China) national Climate center Beijing 100081 China

The future global climate changes induced by the increased atmospheric CO2 concentration is receiving much attention from the scientific community as well as the public. Model simulations and palaeoclimatic data studies show an evident change in temperature and precipitation over China will occur under conditions of the global warming. Possible scenarios of the future climates are given here for China on the basis of synthesizing model simulations and palaeoclimatic data. Most parts of China will experience an increase in temperature, but the warming may be more remarkable in winter in h1e northern half of the country. Increase in precipitation will be seen in nearly every parts of the eastern China, and it will be larger in North and Northeast China. Impacts of the climate changes on the national tourism are assessed. Regions suitable for tourisin development in terms of climate comfortable index will shift northward. Some scenic spots and toruism facilities will be damaged due to sea level rise and increased rainfall. Some regions will benefit from the dimate change, but the tourism industry as a whole will be negatively affected.

关键词： IPCC GLOBAL CLIMATE CHANGES AND THE TOURISM OF CHINA

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国家心力衰竭指南2023(精简版)

中华心力衰竭和心肌病杂志（中英文） 2023年第3期7卷 139-172页

作者：国家心血管病中心国家心血管病专家委员会心力衰竭专业委员会中国医师协会心力衰竭专业委员会中华心力衰竭和心肌病杂志编辑委员会中国循环杂志编辑委员会张健张宇辉黄峻张抒扬王现强不详中国医学科学院阜外医院南京医科大学第一附属医院中国医学科学院北京协和医院

心力衰竭(心衰)是各种心脏疾病的终末阶段,已经成为影响居民健康的重要公共卫生问题。近年来,心衰的诊断、治疗、预防和管理等方面都取得了重大的进展。本指南将结合国内外研究进展,介绍心衰的定义、分类、分期、评估、诊断、预防、治... 详细信息

心力衰竭(心衰)是各种心脏疾病的终末阶段,已经成为影响居民健康的重要公共卫生问题。近年来,心衰的诊断、治疗、预防和管理等方面都取得了重大的进展。本指南将结合国内外研究进展,介绍心衰的定义、分类、分期、评估、诊断、预防、治疗及管理,以及心衰的医疗质量控制等,以期为提高我国心衰综合管理水平提供指导。

关键词：心力衰竭指南中国更新全面

Climate Changes in the 21st Century over the Asia-Pacific Region Simulated by the NCAR CSM and PCM

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Advances in Atmospheric Sciences 2001年第5期18卷 639-658页

作者： Aiguo Dai, G.A. Meehl, W.M. Washington, and T.M.L. Wigley national center for Atmospheric Research P.O. Box 3000, Boulder, CO 80307 ) Email: adai＠ ucar. edu The national center for Atmospheric Research is sponsored by the U S national Science Foundation. national center for Atmospheric Researclt Boulder USA

The Climate System Model (CSM) and the Parallel Climate Model (PCM), two coupled global climate models without flux adjustments recently developed at NCAR, were used to simulate the 20th century climate using historical greenhouse gas and sulfate aerosol forcing. These simulations were extended through the 21st century under two newly developed scenarios, a business-as-usual case (BAU, CO2≈710 ppmv in 2100) and a CO2 stabilization case (STA550, CO2≈540 ppmv in 2100). The simulated changes in temperature, precipitation, and soil moisture over the Asia-Pacific region (10°-60°N, 55°-155°) are analyzed, with a focus on the East Asian summer monsoon rainfall and climate changes over the upper reaches of the Yangtze River. Under the BAU scenario, both the models produce surface warming of about 3-5℃ in winter and 2-3℃ in summer over most Asia. Under the STA550 scenario, the warming is reduced by 0.5-1.0℃ in winter and by 0.5℃ in summer. The warming is fairly uniform at the low latitudes and does not induce significant changes in the zonal mean Hadley circulation over the Asia-Pacific do- main While the regional precipitation changes from single CSM integrations are noisy, the PCM ensemble mean precipitation shows 10%-30% increases north of ～ 30°N and～10% decreases south of ～ 30°N over the Asia-Pacific region in winter and 10%-20% increases in summer precipitation over most of the region. Soil moisture changes are small over most Asia The CSM single simulation suggests a 30% increase in river runoff into the Three Gorges Dam, but the PCM ensemble simulations show small changes in the runoff

关键词： Climate simulation Climate change Asian monsoon Ensemble simulation

Synthesis and Characterization of Some Transition Metal Chelates of 5-(1-Hydroxy-6-Naphthylazo-3-Sodium Sulphonate) Thiobarbituric (L_1) and Barbituric (L_2) Acids

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Journal of Materials Science & Technology 1999年第3期15卷 263-266页

作者： Nabil S. Youssef and K.H.Hegab(Inorganic Chemistry Department, national Research center, Dokki., Giza, Egypt) Natl Res Ctr Dept Inorgan Chem Giza Egypt

Some transition metal chelates of two ligands L1 and L2 were prepared and characterized by elemental analysis. The IR and 1H NMR spectra of several chelates of two ligands L1 and L2 showed the involvement of the azo group in chelation with the transition metaI ions, in most of the studied chelates, and that the two ligands L1 and L2 showed the involvement of the azo group in chelation with the transition metal ions, in most of the studied chelates, and that the two ligands L1 and L2 were coordinated either in the enol or the keto form. IR spetra also showed that Fe(III)-, Ni(II)-, Mn(II)-, VO(II)-L1 and Cu(II)-L2 chelates behaved in a bidentate manner, in contrast with the two (1:1) M:L cobalt chelates with the two ligands are *** analysis indicated the presence of three to twelve water molecules of hydration eliminated on heating up to 150℃ and one or two coordinated water molecules removed at 150~180℃.The octahedral structure is proposed fOr all the chelates, except Cu(II)-L2 and Ni(II)-L1 chelates which have square planar geometry, based on their electronic spectra

关键词： III Acids Hydroxy-6-Naphthylazo-3-Sodium Sulphonate L1 L2 Synthesis and Characterization of Some Transition Metal Chelates of 5 Thiobarbituric and Barbituric

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卵巢病变超声诊断质量控制指标专家共识

中华医学超声杂志（电子版） 2024年第7期21卷 653-656页

作者：国家超声医学质量控制中心北京市超声医学质量控制和改进中心吴青青王红燕姜玉新不详首都医科大学附属北京妇产医院、北京妇幼保健院超声科 100026 中国医学科学院北京协和医学院、北京协和医院超声科疑难重症罕见病国家重点实验室 100730 中国医学科学院北京协和医学院北京协和医院超声科疑难重症罕见病国家重点实验室 100730

卵巢恶性肿瘤是女性生殖系统三大恶性肿瘤之一,死亡率居妇科恶性肿瘤之首[1],尤其是卵巢癌,发病较隐匿,早期多无症状,多数患者就诊时肿瘤已属中晚期[2]。卵巢癌的早期诊断与治疗是提高卵巢癌患者生存率的关键。超声检查作为卵巢疾病影... 详细信息

卵巢恶性肿瘤是女性生殖系统三大恶性肿瘤之一,死亡率居妇科恶性肿瘤之首[1],尤其是卵巢癌,发病较隐匿,早期多无症状,多数患者就诊时肿瘤已属中晚期[2]。卵巢癌的早期诊断与治疗是提高卵巢癌患者生存率的关键。超声检查作为卵巢疾病影像学检查中重要的一环,在卵巢癌诊断中发挥着不可替代的作用。

关键词：女性生殖系统卵巢恶性肿瘤妇科恶性肿瘤影像学检查卵巢病变无症状超声检查超声诊断

特应性皮炎治疗药物应用管理专家共识(2024版)

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中华皮肤科杂志 2024年第2期57卷 97-108页

作者：中国医师协会皮肤科医师分会中华医学会皮肤性病学分会中国医疗保健国际交流促进会皮肤医学分会疑难重症及罕见病国家重点实验室国家皮肤与免疫疾病临床医学研究中心晋红中高兴华吴超不详中国医学科学院北京协和医院中国医科大学附属第一医院

特应性皮炎是一种常见的慢性复发性炎症性皮肤病,既往治疗药物包括外用糖皮质激素、外用钙调磷酸酶抑制剂、口服抗组胺药、系统性免疫抑制剂及糖皮质激素等。近年来,生物制剂及多种小分子药物陆续获批用于本病的治疗。中国医师协会皮肤... 详细信息

特应性皮炎是一种常见的慢性复发性炎症性皮肤病,既往治疗药物包括外用糖皮质激素、外用钙调磷酸酶抑制剂、口服抗组胺药、系统性免疫抑制剂及糖皮质激素等。近年来,生物制剂及多种小分子药物陆续获批用于本病的治疗。中国医师协会皮肤科医师分会、中华医学会皮肤性病学分会、中国医疗保健国际交流促进会皮肤医学分会、疑难重症及罕见病国家重点实验室和国家皮肤与免疫疾病临床医学研究中心组织专家,基于近年特应性皮炎研究进展及国内外指南/共识,结合专家临床经验,针对特应性皮炎治疗药物的临床应用策略、不良反应监测及管理、特殊人群用药管理等内容形成特应性皮炎治疗药物应用管理专家共识。

关键词：皮炎特应性药物疗法管理生物制剂分子靶向治疗药物毒性特殊人群专家共识

Molecular signal transduction in vascular cell apoptosis

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Cell Research 2001年第4期11卷 253-264页

作者： GENG YONG JIAN center for cardiovascular Biology and Atherosclerosis Research, Division of Cardiology, Department of Internal Medicine, University of Texas Houston Health Science center Medical School, 6431 Fannin Street, MSB 6.045, Houston, TX 77030, USA 1center for cardiovascular Biology and Atherosclerosis Research Division of Cardiology Department of Internal Medicine University of Texas Houston Health Science Center Medical School 6431 Fannin Street MSB 6.045 Houston TX 77030 USA

Apoptosis is a form of genetically programmed cell death, which plays a key role in regulation of cellularity in a variety of tissue and cell types including the cardiovascular tissues. Under both physiological and pathophysiological conditions, various biophysiological and biochemical factors, including mechanical forces, reactive oxygen and nitrogen species, cytokines, growth factors, oxidized lipoproteins, etc., ma influence apoptosis of vascular cells. The Fas/Fas ligand/caspase death-signaling pathway, Bcl-2 protein family/mitochondria, the tumor suppressive gene p53, and the proto-oncogene c-myc may be activated in atherosclerotic lesions, and mediates vascular apoptosis during the development of atherosclerosis. Abnormal expression and dysfunction of these apoptosis-regulating genes may attenuate or accelerate vascular cell apoptosis and affect the integrity and stability of atherosclerotic plaques. Clarification of the molecular mechanism that regulates apoptosis may help design a new strategy for treatment of atherosclerosis and ii major complication, the acute vascular syndromes.

关键词： Apoptosis vascular cells caspases atherosclerosis cytokines.

Providing personalized converged services based on flexible network reconfiguration

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Science China(Information Sciences) 2011年第2期54卷 334-347页

作者： HU YuXiang, LAN JuLong & WU JiangXing national Digital Switching System Engineering and Technological Research center, Zhengzhou 450002, China 1. national Digital Switching System Engineering and Technological Research center Zhengzhou 450002 China

Recent developments show a progressing convergence of networks, services, and applications, which results in the necessity for new approaches to provide a ubiquitous experience on converged networks for specialized high data-rate services. A fundamental diversifying attribute for the future physical network convergence paradigm is pressing. In this paper, we make researches on converged resource reconfiguration model of substrate physical network based on hardware virtualization and provide a service oriented network architecture as a network convergence primitive. Based on the idea of hardware virtualization which is performed by platform deformation and component processing with reconfiguration (here, they are realized as reconfigurable routers (RR)), the substrate converged network, which inter-connects various access networks by reconfigurable routers, could be mapped into multiplex service oriented logical networks, supports dynamic reconfiguration due to diversified quality of services under heterogeneous environment, and therefore provides more flexible and high- speed multiple services. In addition, to demonstrate the generality of our model, we provide a prototype of reconfigurable router. The design, implementation and task scheduling as well as both hardware and software reconfiguration process of reconfigurable router are discussed in detail. Our evaluation shows that reconfigurable router is transparent for upper service-providing networks and results in little performance impact on the service delivery when both hardware and software reconfiguration are used.

关键词： network convergence hardware virtualization resource reconfiguration reconfigurable router