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Nano-micro Letters 2013年第4期5卷 303-313页

作者： nasser a.m.barakat Khalil Abdelrazek Khalil Ahmad G.El-Deen Hak yong kim Organic materials and Fiber Engineering Department Chonbuk National University Chemical Engineering Department Minia University mechanical Engineering Department (NPST) King Saud University Dept of Bionano System Engineering College of Engineering Chonbuk National University

Because of the low energy requirement and the environmentally safe byproducts, the capacitive deionization water desalination technology has attracted the attention of many researchers. The important requirements for electrode materials are good electrical conductivity, high surface area, good chemical stability and high specific capacitance. In this study, metallic nanoparticles that are encapsulated in a graphite shell(Cd doped Co/C NPs) are introduced as the new electrode material for the capacitive deionization process because they have higher specific capacitance than the pristine carbonaceous materials. Cd doped Co/C NPs perform better than graphene and the activated carbon. The introduced nanoparticles were synthesized using a simple sol gel technique. A typical sol gel composed of cadmium acetate, cobalt acetate and poly(vinyl alcohol)was prepared based on the polycondensation property of the acetates. The physiochemical characterizations that were used confirmed that the drying, grinding and calcination in an Ar atmosphere of the prepared gel produced the Cd doped Co nanoparticles, which were encapsulated in a thin graphite layer. Overall, the present study suggests a new method to effectively use the encapsulated bimetallic nanostructures in the capacitive deionization technology.

关键词： Capacitive deionization Water desalination Bimetallic nanoparticles Specific capacitance

Hierarchical TiO_2/ZnO Nanostructure as Novel Non-precious Electrocatalyst for Ethanol Electrooxidation

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Journal of materials Science & Technology 2015年第1期31卷 97-105页

作者： Gehan m.K.Tolba nasser a.m.barakat A.m.Bastaweesy E.A.Ashour Wael Abdelmoez mohamed H.El-Newehy Salem S.Al-Deyab Hak Yong Kim Organic materials and Fiber Engineering Department Chonbuk National University Chemical Engineering Department Faculty of EngineeringMinia University BioNanosystem Department Chonbuk National University Department of Chemistry College of ScienceKing Saud University

metal oxides have a higher chemical stability in comparison to metals,so they can be utilized as electrocatalysts if the activity could be *** the composition,the morphology of the nanostructures has a considerable impact on the electrocatalytic *** this work,zinc oxide nano branches-attached titanium dioxide nanofibers were investigated as an economic and stable catalyst for ethanol electrooxidation in the alkaline *** introduced material has been synthesized by electrospinning process followed by hydrothermal ***,electrospinning of colloidal solution consisting of titanium isopropoxide,poly（vinyl acetate） and zinc nanoparticles was performed to produce nanofibers embedding solid *** order to produce TiO2nanofibers containing ZnO nanoparticles,the obtained electrospun nanofiber mats were calcined in air at 600 °*** formed ZnO nanoparticles were exploited as seeds to outgrow ZnO branches around the TiO2nanofibers using the hydrothermal technique at sub-critical water conditions in the presence of zinc nitrate and bis-hexamethylene *** morphology of the final product,as well as the electrochemical measurements indicated that zinc nanoparticles content in the original electrospun nanofibers has a significant influence on the electrocatalytic activity as the best performance was observed with the nanofibers synthesized from electrospun solution containing 0.1 g Zn,and the corresponding current density was 37 mA/***,this study paves a way to titanium dioxide to be exploited to synthesize effective and stable metal oxide-based electrocatalysts.

关键词： Direct ethanol fuel cells Electrospinning Nanofibe

Corrosion and Scaling Threat in Upstream Oil Operation

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World Journal of Engineering and Technology 2024年第2期12卷 426-437页

作者： Nasir Ullattumpoyil Talal m. Al-Ghamdi nasser R. Al-Hajri Southern Area Technical Support Department Saudi Aramco Dhahran KSA

Corrosiveness or scaling is an inherent threat to oil operations. The primary cause for this threat is the presence of water having complex geochemical matrix. Unanticipated water production, particularly if it contains unwanted impurities, can significantly impact hydrocarbon production. The current paper discusses the degree of threat posed to oil operation facilities based on the water characteristics. methodology involved the collection and analysis of water samples from major sources in oil industry such as groundwater, wellheads and seawater. The parameters tested include geochemical, microbiological and pollutants. The lab data was used to develop scaling and corrosion prediction indices such as Langelier Saturation Index (LSI), Ryznar Stability Index (RSI) and Puckorius Scaling Index (PSI). The study indicated varying water chemistry for different sources. mixing of those waters may lead to ionic saturation and scaling in different facilities. Presence of the SRB and GAB in some water sources also posed threat to water system by forming fouling and corrosion. Seawater used for offshore oilfields water injection to maintain reservoir pressure and improve oil recovery showed scaling tendency, whereas under different reservoir pressure, it can cause corrosion. Some of the samples also had corrosion residuals such as iron, which indicated active corrosion. Current study showed higher alkalinity with high sulfate for one groundwater sample with presence of active corrosion residuals such as dissolved iron and manganese. The study showed positive value for LSI which indicated supersaturation of the water samples with respect to calcium carbonate (CaCO3) and scale forming. Similarly, for RSI and PSI, the value was below six which confirmed the scaling potential for all the samples. Even though the index value was pointing towards scaling potential, the geochemistry, microbiology and presence of other impurities indicated corrosion threat to the oil and g

关键词： Formation Water Petroleum Reservoirs Groundwater Saturation Indices Corrosiveness

靶向白细胞介素1β纳米抗体的制备及其对缺氧小鼠心肌细胞凋亡的影响

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中华医学杂志 2024年第22期104卷 2066-2073页

作者：欧阳情王露 nasser moussa Ide 邓刚张新奎游婷苏浩滔朱平华南理工大学医学院广州广东省心血管病研究所南方医科大学附属广东省人民医院(广东省医学科学院)广东省心脏病发病机制与精准防治重点实验室广州市心脏发病机制与重点防治重点实验室广州

目的制备抗白细胞介素1β(IL-1β)纳米抗体, 并观察其对缺氧小鼠心肌细胞凋亡的影响。方法利用DNA重组技术, 使用pET-16b和pHEN1表达载体构建抗IL-1β纳米抗体的重组质粒(pET-16b-4G6m-VHH、pET-16b-5BVP-VHH、pET-16b-5mVZ-VHH和pHEN1-... 详细信息

目的制备抗白细胞介素1β(IL-1β)纳米抗体, 并观察其对缺氧小鼠心肌细胞凋亡的影响。方法利用DNA重组技术, 使用pET-16b和pHEN1表达载体构建抗IL-1β纳米抗体的重组质粒(pET-16b-4G6m-VHH、pET-16b-5BVP-VHH、pET-16b-5mVZ-VHH和pHEN1-4G6m-VHH、pHEN1-5BVP-VHH、pHEN1-5mVZ-VHH, 其中VHH为重链单域抗体, 4G6m-VHH、5BVP-VHH、5mVZ-VHH分别为3种抗IL-1β的纳米抗体), 将构建成功的质粒分别转入大肠杆菌Rosetta2(DE3)表达菌中进行诱导表达及镍柱纯化, 用十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(SDS-PAGE)和Western印迹对表达产物及纯化产物进行鉴定, 并通过酶联免疫吸附试验(ELISA)测定其亲和力。将纯化所得亲和力最高的抗IL-1β纳米抗体(pHEN1-5mVZ-VHH)应用于小鼠HL-1心肌细胞缺氧模型(分为正常对照组、缺氧模型组、空白质粒组及12.5、25.0、50.0 μg/ml pHEN1-5mVZ-VHH处理组), 并检测细胞存活率及凋亡率。结果 SDS-PAGE和Western印迹结果显示, 成功得到相对分子质量约15 000的抗IL-1β纳米抗体;ELISA结果显示, 与pET-16b载体组相比, pHEN1载体组所表达的纳米抗体与IL-1β抗原的亲和力更高(4G6m-VHH组:3.20±0.03比1.20±0.03, PmVZ-VHH组:3.38±0.05比1.62±0.04, Pml及50.0 μg/ml pHEN1-5mVZ-VHH处理组HL-1细胞活性增加[(75.55±2.23)%比(46.90±2.51)%, PmVZ-VHH治疗可减少缺氧小鼠心肌细胞凋亡。

关键词：缺氧心肌细胞细胞凋亡白细胞介素1β 纳米抗体原核表达

Corrosion Penetration and Crystal Structure of AA5022 in HCl Solution and Rare Earth Elements

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Journal of materials Science & Technology 2005年第3期21卷 324-330页

作者： A.A.El-meligi S.H.Sanad A.A.Ismail a.m.barakat Electrochem. and Corrosion Lab. Physical Chemistry Dept. National Research Centre Dokki Cairo EgypElectrochem. and Corrosion Lab. Physical Chemistry Dept. National Research Centre Dokki Cairo EgypElectrochem. and Corrosion Lab. Physical Chemistry Dept. National Research Centre Dokki Cairo EgypChemistry Dept. Faculty of Science Cairo University Cairo Egypt

Al-alloy (AA5022) corrosion penetration (CP) and crystal structure were investigated after running static immersion corrosion tests in 1 mol/L HCl solution and different concentrations of rare earth elements (La3+), (Ce3+) and their combination, at different temperatures. X-ray diffraction (XRD) was used to examine the surface structure before and after immersion, and secondary electron detector (SED) was operated to study surface morphology. In 1 mol/L HCI solution the corrosion penetration increased with increasing temperature and immersion time. The increase of La3+ concentrations up to 1000×10-6 g/L led to the decrease in the corrosion penetration, and the decrease in Ce3+ concentrations up to 50×10-6 g/L decreases the corrosion penetration of the alloy. mix3 (combination of La3+ and Ce3+) dramatically reduced the corrosion penetration. This suggests that a synergistic effect exists between La3+ and Ce3+. The reaction kinetics both in absence and presence of La3+ and Ce3+ and their combination would follow a parabolic rate law. The XRD patterns revealed that the intensities of certain hkl phases are affected. The crystalline structure has not been deformed either before or after testing and there are no additional peaks except that of the as-received alloy. In the case of accelerating CP, the surface morphology shows that the roughness and voids of surface are increased.

关键词： Al-alloy Corrosion penetration Crystal structure XRD

Effects of Rate and Source Organo-mineral material on Forage Yield and Nutritive Value of Barley-Pea mixed under Arid Conditions

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Phyton-International Journal of Experimental Botany 2022年第7期91卷 1483-1493页

作者： Walid Soufan nasser A.Al-Suhaibani Plant Production Department College of Food and Agriculture SciencesKing Saud UniversityRiyadh11451Saudi Arabia

Cereal-legume intercropping plays a vital role in the subsistence food production system that prevails in the arid *** not only provides profitable crop productivity for agricultural communities but also plays an important role in improving soil ***,the present research was conducted to assess the effect of the organic and mineral fertilizers on the forage yield and nutritional value in barley-pea intercropping *** results revealed that the quality of forage grass is significantly influenced by both organic and inorganic ***,organic fertilizer application has significantly influenced the dry matter(Dm),crude ash(CA),crude protein(CP),neutral detergent fiber(NDF),and acid detergent fiber(ADF).Among the treatments,organic fertilizer added at rate of 35 m^(−3) ha^(−1) produced the maximum fresh and dry matter in barley and *** addition,the same level of organic fertilizer also improved silage composition by significantly increasing the protein and fiber content and showed highest the *** on overall results,it is concluded that organic fertilizer treatment(35 m^(−3) ha^(−1))has the potential as an effective strategy to improve the productivity and nutritional quality of the barley-pea intercropping system in arid *** results revealed that organic fertilizer can be utilized in sustainable agricultural as a source of nutrients for numerous various crops under arid conditions.

关键词： Organic fertilizer barley pea yield quality hay silage

Oncogenic BRAF^(V600E) induces microglial proliferation through extracellular signal-regulated kinase and neuronal death through c-Jun N-terminal kinase

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Neural Regeneration Research 2023年第7期18卷 1613-1622页

作者： Qing Ye Pranay Srivastava nasser Al-Kuwari Xiqun Chen Department of Neurology Massachusetts General HospitalHarvard Medical SchoolCharlestownMAUSA Department of Neurology Longhua HospitalShanghai University of Traditional Chinese MedicineShanghaiChina Aligning Science Across Parkinson’s(ASAP)Collaborative Research Network Chevy ChaseMDUSA

Activating V600E in v-Raf murine sarcoma viral oncogene homolog B(BRAF)is a common driver mutation in cancers of multiple tissue origins,including melanoma and ***^(V600E) has also been implicated in *** present study aims to characterize BRAF^(V600E) during cell death and proliferation of three major cell types of the central nervous system:neurons,astrocytes,and *** primary cultures(primary cortical mixed culture)and cell lines of glial cells(BV2)and neurons(SH-SY5Y)were ***^(V600E) and BRAF^(WT) expression was mediated by lentivirus or *** of downstream effectors(extracellular signal-regulated kinase 1/2 and JNK1/2)were achieved by *** astrocytes and microglia,BRAF^(V600E) induces cell proliferation,and the proliferative effect in microglia is mediated by activated extracellular signal-regulated kinase,but not c-Jun N-terminal *** medium from BRAF^(V600E)-expressing microglia induced neuronal *** neuronal cells,BRAF^(V600E) directly induces neuronal death,through c-Jun N-terminal kinase but not extracellular signal-regulated *** further show that BRAF-related genes are enriched in pathways in patients with Parkinson’s *** study identifies distinct consequences mediated by distinct downstream effectors in dividing glial cells and in neurons following the same BRAF mutational activation and a causal link between BRAF-activated microglia and neuronal cell death that does not require physical *** provides insight into a possibly important role of BRAF in neurodegeneration as a result of either dysregulated BRAF in neurons or its impact on glial cells.

关键词： astrocytes cell death cell proliferation inflammation microglia mutation neurons v-Raf murine sarcoma viral oncogene homolog B(BRAF)

Optimization Ensemble Weights model for Wind Forecasting System

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Computers, materials & Continua 2022年第11期73卷 2619-2635页

作者： Amel Ali Alhussan El-Sayed m.El-kenawy Hussah nasser AlEisa m.El-SAID Sayed A.Ward Doaa Sami Khafaga Department of Computer Sciences College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia Department of Communications and Electronics Delta Higher Institute of Engineering and TechnologyMansoura35111Egypt Faculty of Artificial Intelligence Delta University for Science and TechnologyMansoura35712Egypt Electrical Engineering Department Faculty of EngineeringMansoura UniversityMansoura35516Egypt Delta Higher Institute of Engineering and Technology(DHIET) Mansoura35111Egypt Department of Electrical Engineering Faculty of Engineering at ShoubraBenha UniversityCairo11629Egypt Faculty of Engineering Delta University for Science and TechnologyGamasaMansoura11152Egypt

Effective technology for wind direction forecasting can be realized using the recent advances in machine ***,the stability and safety of power systems are expected to be significantly ***,the unstable and unpredictable qualities of the wind predict the wind direction a challenging *** paper proposes a practical forecasting approach based on the weighted ensemble of machine learning *** weighted ensemble is optimized using a whale optimization algorithm guided by particle swarm optimization(PSO-Guided WOA).The proposed optimized weighted ensemble predicts the wind direction given a set of input *** conducted experiments employed the wind power forecasting dataset,freely available on Kaggle and developed to predict the regular power generation at seven wind farms over forty-eight *** recorded results of the conducted experiments emphasize the effectiveness of the proposed ensemble in achieving accurate predictions of the wind *** addition,a comparison is established between the proposed optimized ensemble and other competing optimized ensembles to prove its ***,statistical analysis using one-way analysis of variance(ANOVA)and Wilcoxon’s rank-sum are provided based on the recorded results to confirm the excellent accuracy achieved by the proposed optimized weighted ensemble.

关键词： Guided Whale Optimization Algorithm(Guided WOA) forecasting machine learning weighted ensemble model wind direction

Transfer Learning for Chest X-rays Diagnosis Using Dipper Throated Algorithm

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Computers, materials & Continua 2022年第11期73卷 2371-2387页

作者： Hussah nasser AlEisa El-Sayed m.El-kenawy Amel Ali Alhussan mohamed Saber Abdelaziz A.Abdelhamid Doaa Sami Khafaga Department of Computer Sciences College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversityRiyadh11671Saudi Arabia Department of Communications and Electronics Delta Higher Institute of Engineering and TechnologyMansoura35111Egypt Faculty of Artificial Intelligence Delta University for Science and TechnologyMansoura35712Egypt Electronics and Communications Engineering Department Faculty of EngineeringDelta University for Science and TechnologyMansoura35712Egypt Department of Computer Science Faculty of Computer and Information SciencesAin Shams UniversityCairo11566Egypt Department of Computer Science College of Computing and Information TechnologyShaqra University11961Saudi Arabia

most children and elderly people worldwide die from pneumonia,which is a contagious illness that causes lung *** diagnosing pneumonia from chest X-ray images,many deep learning models have been put *** goal of this research is to develop an effective and strong approach for detecting and categorizing pneumonia *** varying the deep learning approach,three pre-trained models,GoogLeNet,ResNet18,and DenseNet121,are employed in this research to extract the main features of pneumonia and normal *** addition,the binary dipper throated optimization(DTO)algorithm is utilized to select the most significant features,which are then fed to the K-nearest neighbor(KNN)classifier for getting the final classification *** guarantee the best performance of KNN,its main parameter(K)is optimized using the continuous DTO *** test the proposed approach,six evaluation metrics were employed namely,positive and negative predictive values,accuracy,specificity,sensitivity,and ***,the proposed approach is compared with other traditional approaches,and the findings confirmed the superiority of the proposed approach in terms of all the evaluation *** minimum accuracy achieved by the proposed approach is(98.5%),and the maximum accuracy is(99.8%)when different test cases are included in the evaluation experiments.

关键词： metaheuristic pneumonia dipper throated optimization KNN

Investigation of SARS-CoV-2 main Protease Potential Inhibitory Activities of Some Natural Antiviral Compounds Via molecular Docking and Dynamics Approaches

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Phyton-International Journal of Experimental Botany 2022年第5期91卷 1089-1104页

作者： Nada m.mostafa muhammad I.Ismail Amr m.El-Araby Dina m.Bahgat Ahmed m.Elissawy Ahmed m.mostafa Omayma A.Eldahshan Abdel nasser B.Singab Department of Pharmacognosy Faculty of PharmacyAin Shams UniversityCairo11566Egypt Department of Pharmaceutical Chemistry Faculty of PharmacyThe British University in EgyptCairo11837Egypt Department of Pharmaceutical Chemistry Faculty of PharmacyAin Shams UniversityCairo11566Egypt Department of Biochemistry Faculty of PharmacyAin Shams UniversityCairo11566Egypt Center for Drug Discovery and Development Research Ain Shams UniversityCairo11566Egypt

Coronaviruses caused an outbreak pandemic disease characterized by a severe acute respiratory distress syndrome leading to the infection of more than 200 million patients and the death of more than 4 million *** primary treatment is either supportive or *** products have an important role in the development of various ***,screening of natural compounds with reported antiviral activities can lead to the discovery of potential inhibitory entities against *** the current study,an in-silico molecular docking experiment was conducted on the effects of some of these natural antiviral phytoconstituents,(e.g.,procyanidin B2,theaflavin,quercetin,ellagic acid,caffeoylquinic acid derivatives,berginin,eudesm-1β,6α,11-triol and arbutin),on the crystal structure of SARS-CoV-2 main protease(PDB ID:6w63)using AutoDock-Vina *** of the docked compounds revealed good binding affinity,with procyanidin B2(–8.6 Kcal/mol)and theaflavin(–8.5 Kcal/mol)showing a better or similar binding score as the ligand(–8.5 Kcal/mol).molecular dynamics simulations were carried out at 100 ns and revealed that procyanidin B2 forms a more stable complex with SARS-CoV-2 main protease than *** B2,theaflavin,and 4,5-dicaffeoylquinic acid were evaluated for toxicity by ProTox-II webserver and were non-toxic according to the predicted LD50 values and safe on different organs and ***,these phytoconstituents showed good ADmE properties and acceptable lipophilicity,as evaluated using *** the tested compounds,procyanidin B2 showed the highest lipophilic *** is worth mentioning that these natural inhibitiors of SARS-CoV-2 main protease are components of green and black tea that can be used as a supporting supplement for COVID patients or as potential nuclei for further drug design and development campaigns.

关键词： Coronavirus natural products SARS-CoV-2 main protease molecular docking molecular dynamics tea