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Necrotizing fasciitis as a complication of taxanes: a case report

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Journal of Cancer Metastasis and Treatment 2018年第1期4卷 402-405页

作者： nasser mohammed amer Rabia Niaz Department of General Surgery King Fahad Hospital of the UniversityImam Abdulrahman Bin Faisal UniversityAl Khobar 34445Saudi Arabia

Necrotizing fasciitis is a rare complication of chemotherapy,however,few reports were published as a specific complication of *** are reporting this rare complication of a lady who was treated with taxanes as an adjuvant therapy for her breast cancer who was referred to us from the medical department and turned out to be necrotizing fasciitis in her right *** are also presenting the literature review of this type of complication.

关键词： Necrotizing fasciitis breast cancer taxanes,docetaxel complication of chemotherapy

Metastatic breast cancer:an unusual cause of diplopia

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Journal of Cancer Metastasis and Treatment 2016年第1期2卷 123-126页

作者： nasser mohammed amer Gareth Bashir Arikoge Ogedegbe Ibtisam Saeed Department of General Surgery University of DammamAl Khobar 40262Kingdom of Saudi Arabia Department of General Surgery King George HospitalIlford IG38YBUK Department of Pathology Queens HospialRomford RM70AGUK

While secondary solid cancer into the eye orbit is rare,it is the most common site for primary metastasis in female breast *** report a case of a sixty-six years old woman presenting to her optician with complaints of double *** resonance imaging revealed an invasive lesion in the superior and medial rectus muscles of the right orbit,biopsy of which confirmed this as an infiltrating breast *** of the primary lesion showed an advanced invasive ductal carcinoma of the right *** was then treated with radiotherapy to the orbit and a non steroidal aromatase inhibitor Anastrozol(Arimidex®).We herein review and discuss the literature,epidemiology,mechanism of tumor spread,the“seed and soil”theory,clinical presentation,pathology,and management of this uncommon presentation.

关键词： Metastatic breast cancer diplopia ocular metastasis

The Impact of Blood Transfusion on the Efficiency of Stem Cell Transplants

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Case Reports in Clinical Medicine 2024年第8期13卷 328-338页

作者： amer Saud AL-Humaidan Saleh Saud Almutairi mohammed Hussain Khubrani Raffah Mahdi Bajudah Waleed Mohammad Alzabidi mohammed Hafiz Almasabi Bader mohammed Saleh Alhomaid Waad Ali Alshehri Wejdan Saleh Alghamdi Raghad Abdullah Alwthinani Department of Pathology and Laboratory King Abdulaziz Medical City Ministry of National Guard Health Affairs Riyadh Saudi Arabia

Background: While blood product transfusion is essential for managing hematologic deficits in Allogenic Hematopoietic stem cell transplant (AHSCT) recipients, it has risks including infectious disease transmission, alloimmunization, and transfusion reactions. These risks have sparked an ongoing debate regarding the overall impact of transfusions on patient outcomes. Thus, this study aimed to evaluate the impact of Red Blood Cells (RBCs) and/or platelet transfusion on the infection incidence and overall survival in AHSCT patients. Methods: We performed a retrospective analysis of clinical and laboratory data of sixty adult patients with primary malignant hematological disorder who had undergone AHSCT. Participants’ data were categorized into two groups;Group 1 (low transfusion group) consisted of patients receiving 10 units. Quantitative data were expressed as mean ± SD. The t-test of significance and Chi-square (χ2) test were used, with p ≤ 0.05 considered significant. Result: A total of 60 patients’ data was included. In Group 1, out of 30 patients, 13 (43.33%) developed infections. In contrast, Group 2 had 21 (70%) out of 30 patients develop infections. Group 1 had a higher survival rate (57.8%) than Group 2 (transfusion > 10 units) (46.2%) with a chi-square value = 23.56, and p-value Conclusion: The volume of blood product transfusions has a considerable impact on patient outcomes, particularly infection and survival rates. Additional long-term prospective studies and larger randomized controlled trials are needed to strengthen the evidence for determining transfusion protocols for these patients.

关键词： Hematologic Neoplasms Hematopoietic Stem Cell Transplantation Blood Transfusion Survival Rate

Comparative studies on numerical sensitivity of different scenarios of enhanced oil recovery by water-alternating-gas(CO_(2))injection

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Petroleum Research 2023年第4期8卷 505-513页

作者： Saddam mohammed mohammed nasser Achinta Bera Vivek Ramalingam School of Energy Technology Pandit Deendayal Energy UniversityGandhinagarGujarat382007India

Enhanced oil recovery by CO_(2) injection technology(CO_(2)-EOR)plays a crucial role in enhancing oil production and the permanent sequestration of anthropogenic CO_(2) in depleted oil ***,the availability of CO_(2) in oil field locations and its mobility in contrast with reservoir fluids are prime challenges in CO_(2)-*** cost of CO_(2) and its availability at the oil fields has prompted investigations on efficient injection of CO_(2) at the fields to achieve the best sweep efficiency *** strategies such as water-alternating-gas(WAG),simultaneous vertical and horizontal WAG,simultaneous water injection into the aquifer and vertical WAG,water and gas injection simultaneously but separately(SS-WAG),and water and gas injection simultaneously but not separately(SNS-WAG)play a significant role,as well as the purity of CO_(2).In this work,the significance of the above criteria was investigated indi-vidually and in *** coupled sequence of injection rate,soaking time,WAG ratio,and purity of injected CO_(2) for enhancement of oil production were delineated.A realistic reservoir simulation model conceptualizing the CO_(2)-EOR system with five spot injection patterns was developed by the company *** history-matched model that was developed was used to investigate the sensitivity of the coupled effects to the criteria listed above on oil *** investigations quantitatively emphasized that purity and soaking time of CO_(2) have an inverse effect in the oil production rate and that SNS-WAG resulted in a better oil production rate than SS-WAG.

关键词： Water-alternating-gas Enhanced oil recovery Sensitivityanalysis Modelingand simulation Simultaneouslybut not separately water-alternating-gas(SS-WAG) Simultaneously pressure maintenance and WAG

Exploring the Prevalence and Contributing Factors of Depression among Sickle Cell Anemia Patients in Saudi Arabia’s Jazan Region

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International Journal of Mental Health Promotion 2024年第5期26卷 351-359页

作者： Abdullah A.Alharbi Ahmad Y.Alqassim mohammed A.Muaddi Najat H.Aldubayyan Rana I.Abuhadi Futon A.Akoor Sarah J.Mobarki Imtenan A.Oberi Ghaidaa H.Alharbi Yara Ajeebi Adnan M.Alkhayat Hafiz Malhan mohammed Bakkar Anwar M.Makeen Family and Community Medicine Department Faculty of MedicineJazan UniversityJazan45142Saudi Arabia Laboratory Department King Fahd Central HospitalMinistry of HealthJazan45142Saudi Arabia Internal Medicine Department Prince Mohammad bin Nasser HospitalMinistry of HealthJazan45142Saudi Arabia Hematology Department King AbdulAziz Medical City for National GuardRiyadh11426Saudi Arabia

Sickle Cell Anemia(SCA)is a prevalent genetic condition in Saudi Arabia,particularly in the Jazan *** study’s purpose was to assess the prevalence of de-pression among individuals with SCA in this area and to identify the factors associated with this *** study involved 391 adult participants,all patients in the hematology center of Prince mohammed bin nasser Hospital(PMNH).Data was collected through an anonymous interview questionnaire–the Arabic version of the Patient Health Questionnaire-9(PHQ-9)–between March–May *** questionnaire covered socio-demographic information and variables related to the participant’s SCA history,such as pain levels,frequency of pain,hospitalization duration,and frequency of blood *** variables underwent Chi-square and One-way ANOVA testing,followed by multivariate *** study found a 42%prevalence of depression among the SCA *** significantly linked with heightened depression levels included being widowed or divorced,experiencing frequent and severe pain,and longer duration of hospital *** educational level of at least a bachelor’s degree was also a significant *** study reveals a high prevalence of depression among SCA patients in the Jazan *** underscores the need for policymakers to educate both physicians and patients about the importance of mental health in SCA *** study also highlights the need for more research into the specific causes and effects of depressive symptoms in SCA patients to inform the creation of effective management plans.

关键词： Sickle cell anemia prevalence depression public health policy Jazan region Saudi Arabia

Synthesis, spectral, optical and anti-inflammatory activity of complexes derived from 2-aminobenzohydrazide with some rare earths

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Journal of Rare Earths 2015年第7期33卷 758-764页

作者： nasser mohammed Hosny El Sayed A.El Morsy Yousery E.Sherif Chemistry Department Faculty of Science Port-Said University Clinical Pharmacology Department Faculty of Medicine Mansoura University Pharmacology and Therapeutics Department Qassim College of Medicine Qassim University Department of Chemistry Faculty of Science and Arts Taibah University

Three new metal complexes derived from Er（Ⅲ）, Dy（Ⅲ） and Zr（Ⅳ） with 2-aminobenzohydrazide （ABH） were synthesized and characterized by elemental analyses, IR, ^1H-NMR, ES-MS and transmission electron microscopy （TEM）. The morphology and the particle size were determined by TEM. The results showed that the ligand acted as neutral bi-dentate coordinating to the metal ions through the carbonyl oxygen and amidic amino nitrogen. The aromatic amine group remained inert towards coordination. The optical band gap was measured and found to be 3.3, 3.5 and 4.3 eV for Er（Ⅲ）, Dy（Ⅲ） and Zr（Ⅳ）, respectively. The optical band gap values indicated a semi-conducting nature of the investigated complexes. The anti-inflammatory and analgesic activities of the tested compounds were determined and compared with standard meloxicam.

关键词： Er(Ⅲ) Dy(Ⅲ) Zr(Ⅳ) metal complexes optical band gap rare earths

New experimental study on the DC flashover voltage of polymer insulators:combined effect of surface charges and air humidity

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High Voltage 2019年第4期4卷 316-323页

作者： mohammed amer Jeff Laninga William McDermid David R.Swatek Behzad Kordi Department of Electrical and Computer Engineering University of Manitoba75 Chancellor's CircleWinnipegManitobaCanada R3T 5V6 Manitoba Hydro WinnipegManitobaCanada R3M 3T1

This research provides conclusions that can partially cover the lack of knowledge related to the effects of ambient atmospheric conditions on DC electric power *** polymer insulating materials are used for completing this research *** a climate chamber,the relative humidity is controlled and adjusted from 20%to 80%***,the samples are charged with positive or negative charges by applying±20 kV to the corona-generating ring of *** surface potential is measured using an electrostatic voltmeter and is converted into surface charge density later by applying the probe response matrix *** pre-charged samples are then stressed with high-voltage negative or positive DC values inside the climate chamber over a range of controlled values of the surrounding air humidity until flashover takes *** space charges,which can drift in the air gap to reach the solid surface,are highly affected by the level of the relative humidity of the surrounding ***,increasing humidity results in a reduction of the DC flashover inception voltage and a shorter time to flashover regardless of the voltage ***,the positive or negative flashover inception voltage of both materials increases with pre-deposited negative charges while it decreases with pre-deposited positive charges.

关键词： charges flash humidity

Numerical investigation of modal and fatigue performance of a horizontal axis tidal current turbine using fluid-structure interaction

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Journal of Ocean Engineering and Science 2019年第4期4卷 328-337页

作者： Habib Ullah Muzamil Hussain Naseem Abbas Hassaan Ahmad mohammed amer Muhammad Noman Faculty of Engineering and Technology University of LahoreLahore 54000Pakistan Department of Mechanical Engineering NFC Institute of Engineering and TechnologyMultan 60000Pakistan School of Mechanical Engineering Chung-Ang UniversitySeoul 06974Republic of Korea Department of Mechanical Engineering National Chiao Tung UniversityHsinchuTaiwan

The tidal power has the potential to play a vital role in a sustainable energy *** main objective of this paper is to investigate the performance and fatigue life of tidal current turbine(TCT)using fluid structure interaction(FSI)*** performance of TCT was predicted using Ansys *** performance curve,pressure distribution on the blade,and velocity streamline were visualized for eight repetitive analyses at different tip speed *** hydrodynamic load calculated from CFD analysis was transferred to FEA model for investigation of the structural response of *** analysis was performed to examine the mode shapes and natural frequencies of *** fatigue analysis were performed and number of cycles and safety factor at different equivalent alternating stresses were *** results of the simulation confirm that the turbine has a maximum value of the coefficient of performance atλ=5,the turbine operating frequency is not close to its natural frequency,and it is safe under the applied fatigue loads with a high factor of safety.

关键词： Tidal current turbine Fluid-structure interaction Fatigue performance Computational Fluid Dynamic Blade element

Abscess of the caudate lobe of the liver, a rare disease with a challenging management: a case report

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The Journal of Biomedical Research 2013年第5期27卷 430-434页

作者： nasser A. Al amer Walid M. Abd El Maksoud Consultant of General Surgery Aseer Central Hospital Assistant Professor General Surgery Department Faculty of Medicine King Khalid University

We reported a rare case of abscess of the caudate lobe of the liver in a 60-year old man. We first tried computed tomography （CT） guided percutaneous drainage of the abscess but failed to eradicate the infection. Deterioration of the general condition of the patient necessitated open surgical drainage, which resulted in cure of the abscess. The peculiar anatomical location of caudate lobe abscess introduces a great challenge for the surgeon in plan- ning the appropriate management and paucity of patients with caudate lobe abscess has led to lack of guidelines for management. The non-operative interventional radiology approach has become the therapeutic choice for pyo- genic liver abscess, but is it applicable also for caudate lobe abscess？

关键词： caudate lobe percutaneous drainage open surgical drainage pyogenic liver abscess