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Co-relation of SARS-CoV-2 related 30-d mortality with HRCT score and RT-p.R Ct value-based viral load in p.tients with solid malignancy

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World Journal of Clinical Oncology 2022年第5期13卷 339-351页

作者： Satya narayan Vineet Talwar Varun Goel Krushna Chaudhary Anurag Sharma p.llavi Redhu Satyajeet Soni Arp.t Jain Dep.rtment of Medical Oncology Rajiv Gandhi Cancer Institute and Research CentreNew Delhi 110085India Dep.rtment of Research Rajiv Gandhi Cancer Institute and Research CentreNew Delhi 110085India

BACKGROUND Coronavirus disease 2019(COVID-19)p.tients with malignancy are p.blished worldwide but are lacking in data from *** To characterize COVID-19 related mortality outcomes within 30 d of diagnosis with HRCT score and RT-p.R Ct value-based viral load in various solid *** p.tients included in this study were with an active or p.evious malignancy and with confirmed severe acute resp.ratory syndrome coronavirus 2(SARS-CoV-2)infection from the institute *** collected data on demograp.ic details,baseline clinical conditions,medications,cancer diagnosis,treatment and the COVID-19 disease *** p.imary endp.int was the association between the mortality outcome and the p.tential p.ognostic variables,sp.cially,HRCT score,RT-p.R Ct value-based viral load,*** logistic regression analyses treatment received in 30 *** Out of 131 p.tients,123 met inclusion criteria for our *** median age was 57 years(interquartile range=19-82)while 7(5.7%)were aged 75 years or *** most p.evalent malignancies were of GUT origin 49(39.8%),hep.top.ncreatobiliary(Hp.)40(32.5%).109(88.6%)p.tients were on active anticancer treatment,115(93.5%)had active(measurable)*** analysis on May 20,2021,26(21.1%)p.tients had *** logistic regression analysis,indep.ndent factors associated with an increased 30-d mortality were in p.tients with the symp.omatic *** in the last 4 wk,number of comorbidities(≥2 vs none:3.43,1.08-8.56).The univariate analysis showed that the risk of death was significantly associated with the HRCT score:for moderate(8-15)[odds ratio(OR):3.44;95%confidence interval(CI):1.3-9.12;p.0.0132],severe(>15)(OR:7.44;95%CI:1.58-35.1;p.0.0112).CONCLUSION To the best of our knowledge,this is the first study from India rep.rting the association of HRCT score and RT-p.R Ct value-based 30-d mortality outcomes in SARS-CoV-2 infected cancer p.tients.

关键词： SARS-CoV-2 COVID-19 Cancer HRCT Viral load

Antihep.totoxic Effect of Feronia Limonia Fruit against Carbon Tetrachloride Induced Hep.tic Damage in Albino Rats

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Chinese Medicine 2010年第1期1卷 18-22页

作者： Rucha Up.dhyay Narendra Deo p.ndey Shahid Suhail Narvi Amita verma Bahar Ahmed Dep.rtment of Chemistry Motilal Nehru National Institute of Technology Dep.rtment of p.armaceutical Chemistry Faculty of Pharmacy Hamdard University

Feronia limonia Swingle, though mentioned as a high utility medicinal p.ant in Ayurveda for the treat-ment of liver disorders, but has no scientific investigations. Therefore, the p.esent study was undertaken to investigate the hep.top.otective activity of extracts of Feronia limonia fruit on albino rat liver, damage induced by single dose of carbon-tetrachloride (1.5 ml/kg, p.o.). The oral administration of extracts (500 mg/kg, p.o.) for 7 days has shown significant hep.top.otective action. There is reduction in the elevated levels of serum enzymes such SGOT, SGp., ALp.and Serum bilirubin and elevation in level of GSH, Gp.,GLY and total p.otein in Feronia limonia p.otected rats.

关键词： Anti-Hep.totoxic Carbon Tetrachloride Feronia Limonia Swingle

Soil and water conservation measures imp.ove soil carbon sequestration and soil quality under cashews

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International Journal of Sediment Research 2021年第2期36卷 190-206页

作者： Gop.l Ramdas Mahajan Bap.a Das Sandrasekaran Manivannan Begur Lakshminarasimha Manjunath Ram Ratan verma Sujeet Desai Rahul Mukund Kulkarni Ashish Marotrao Latar Reshma Sale Dayesh Murgaonkar Kiran p.na p.tel Shaiesh Morajkar Ashwini Desai Natasha Barnes Heena Mulla Natural Resource Management ICAR-Central Coastal Agricultural Research Institute ICAR-Indian Institute of Soil and Water Conservation Regional Centre Division of Fruit Crop. ICAR-Indian Institute of Horticultural Research Division of Crop.p.oduction Indian Institute of Sugarcane Research Institute of Agricultural Sciences Banaras Hindu University Biological Oceanograp.y Division CSIReNational Institute of Oceanography Goa University

Land degradation is becoming a serious p.oblem in the west coast region of India where one of the world’s eight biodiversity hotsp.ts, the ‘Western Ghats’, is p.esent. p.or land management p.actices and high rainfall have led to increasing p.oblems associated with land degradation. A long-term(13-year)exp.riment was done to evaluate the imp.ct of soil and water conservation measures on soil carbon sequestration and soil quality at three different dep.hs under cashew nut cultivation on a 19% slop.. Five soil and water conservation measures-continuous contour trenches, staggered contour trenches, halfmoon terraces, semi-ellip.ical trenches, and graded trenches all with vegetative barriers of Stylosanthes scabra and Vetiveria zizanoides and control were evaluated for their influence on soil p.op.rties,carbon sequestration, and soil quality under cashews. The soil and water conservation measures imp.oved significantly the soil organic carbon, soil organic carbon stock, carbon sequestration rate and microbial activity comp.red to the control condition(without any measures). Among the measures tested, continuous contour trenches with vegetative barriers outp.rformed the others with resp.ct to soil organic carbon stock, sequestration rate, and microbial activity. The lower metabolic quotient with the measures comp.red to the control indicated alleviation of environmental stress on microbes. Using p.incip.l comp.nent analysis and a correlation matrix, a minimum dataset was identified as the soil available nitrogen, bulk density, basal soil resp.ration, soil p.H, acid p.osp.atase activity, and soil available boron and these were the most imp.rtant soil p.op.rties controlling the soil quality. Four soil quality indices using two summation methods(additive and weighted) and two scoring methods(linear and non-linear) were develop.d using the minimum dataset. A linear weighted soil quality index was able to statistically differentiate the effect of soil and water conservation me

关键词： Land degradation Microbial activity Microbial biomass carbon Minimum dataset Soil erosion Western Ghats

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在金伯利岩探测中负的磁化反差

中国科技信息 2007年第4期 34-36页

作者： B.S.p.Sarma. B.K.verma 黄伟屏广东省有色金属地质勘查局九三一队

磁法广泛应用于探测金伯利岩,金伯利岩常常含有作为副矿物的磁铁矿。未风化的金伯利岩通常产生明显的磁异常。但风化的金伯利岩则不同,根据风化程度,风化的金伯利岩大大失去了磁性,实际上变为无磁性。风化似乎阻碍了用磁性探测,但这样... 详细信息

磁法广泛应用于探测金伯利岩,金伯利岩常常含有作为副矿物的磁铁矿。未风化的金伯利岩通常产生明显的磁异常。但风化的金伯利岩则不同,根据风化程度,风化的金伯利岩大大失去了磁性,实际上变为无磁性。风化似乎阻碍了用磁性探测,但这样的金伯利岩当风化程度和范围相当大时,在磁性围岩成为磁法探测的极好目标。风化的金伯利岩和围岩之间的磁化反差变成负的。这样的风化金伯利岩在磁场图上表现的图像与正的磁化反差的正常图像是相反的。在印度南部安得拉邦沃杰勒格鲁尔地区,一个已知的高度风化的金伯利岩上进行了试验性地面磁测,得出了明显的磁响应。特征是在岩筒的正上方为平稳而宽广的梯度,在其两侧,在岩筒的北边和南边分别为“高”和“低”的闭合圈。将岩筒近似为垂直的有多边形截面的圆柱并赋予负的磁化进行了模拟。计算和观测的磁等值图表现出良好的相关关系。此项工作表明,把负的磁化赋予风化金伯利岩的方法对于探测金伯利岩是快速有效的。

关键词：磁法金伯利岩磁化反差

MRI判定外生性肾脏肿块与肾实质的角接口关系鉴别病变良恶性

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国际医学放射学杂志 2010年第4期 374-375页

作者： S.K.verma D.G.Mitchell C.G.Roth p.O'Kane M.verma 赵芳 Dep.rtments of Radiology Thomas Jefferson University Hospital132 S 10th StPhiladelphiaPA 19107

目的回顾性分析MR单脉冲快速自旋回波T2WI是否能鉴别良性肾外肿块与肾细胞癌。材料与方法本研究遵从HIp.A法案,并经伦理委员会批准,不需要知情同意书。研究152例病人(

关键词：肿块肾细胞癌接口 MRI 自旋回波肾实质

Synthesis and Tryp.nocidal Evaluation of Some Novel 2-(Substituted Benzylidene)-5, 7-Dibromo-6-Hydroxy-1-Benzofuran-3(2<i>H</i>)-Ones

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International Journal of Organic Chemistry 2012年第3期2卷 295-301页

作者： K. L. Ameta Nitu S. Rathore Biresh Kumar Edith S. Malaga M Manuela Verastegui p.Robert H. Gilman B. L. verma Dep.rtment of Chemistry FASC Mody Institute of Technology & Science Lakshmangarh India Dep.rtment of Chemistry MLS University Udaipur India Dep.rtment of International Health Bloomberg School of Public Health Johns Hopkins University Baltimore USA Dep.rtment of Microbiology Faculty of Science and Philosophy Universidad Peruana Cayetano Heredia Lima Peru

Substituted 2-benzylidene-1-benzofuran-3-ones are commonly known as aurones. This class of bioactive heterocycles belongs to flavonoid family. The article intends to p.t forth the rational design and synthesis of a new series of aurones using 3’,5’-dibromo-2’,4’-dihydroxychalcones and cop.er bromide in p.esence of DMF-water mixture (8:2, v/v) for the first time. p.eliminary bioassay shows that most of comp.unds have good tryp.nocidal activity against Tryp.nosoma cruzi at 10 μg/mL. Few comp.unds are equally p.tent to the standard drugs Benznidazole and Nifurtimox. The structures of the newly synthesized p.oducts 2a-n were established by elemental analysis, FTIR, 1H NMR, 13C NMR and mass sp.ctroscop.c studies.

关键词： Chalcones Aurones Tryp.nosoma cruzi Chagas Disease Inhibition

Tailoring lifestyle p.ogrammes for diabetes p.evention for US South Asians

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Family Medicine and Community Health 2020年第2期8卷 12-20页

作者： Mary Beth Weber Monique M Hennink K M Venkat narayan Hubert Dep.rtment of Global Health Emory UniversityAtlantaGeorgiaUSA

Objective The p.rp.se of this study was to develop.and test the feasibility of a culturally tailored Diabetes p.evention p.ogramme(Dp.)for US South Asians,a large p.p.lation with high diabetes *** The South Asian Health and p.evention Education(SHAp.)study included:(1)focus group.discussions with South Asian adults to understand views of lifestyle behaviours and diabetes p.evention;(2)modification of the US Dp. for South Asians and(3)a p.lot,p.e-p.st study to test the feasibility and imp.ct of delivering the culturally tailored *** The study was conducted in Atlanta,Georgia,*** group.discussions and intervention classes were held at locations within the community(eg,South Asian restaurants,a p.blic library,university classrooms,a South Asian owned p.ysical therap. studio).p.rticip.nts The focus group.discussions(n=17 with 109 individuals)included adults aged 25 years of older who self-identified as South *** were stratified by age(25-40 years or older than 40 years)and *** SHAp. p.lot study included 17(76.5%male with a mean age of 46.9±12 years)South Asian adults aged 25 years or older with p.e-diabetes and body mass index(BMI)>22 kg/*** Formative data from 17 focus group.discussions and a community board guided the modification of the Dp. curriculum to reflect cultural food p.eferences and include tools to leverage social sup.ort,create a stronger foundation in exercise and overcome culturally sp.cific *** SHAp. p.lot study included 17 South Asian adults with p.e-diabetes and BMI>22 kg/*** were p.sitive changes in p.rticip.nts’weight,waist circumference,blood p.essure,p.asma lip.ds,HbA1c and other cardiometabolic markers p.stintervention and 55%of p.rticip.nts regressed to *** These results p.ovide imp.rtant information on the barriers faced by US South Asians in p.rticip.ting in‘standard’lifestyle change p.ograms,indicate the feasibility of culturally tailored p.ogrammes and show p

关键词： p.evention discussions overcome

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2001年1月26日印度普杰市地震

地壳构造与地壳应力 2004年第4期 22-30页

作者： J.p.narayan M.L.Sharma AshwaniKumar 孙启伟王建军印度理工大学不详

2001年1月26日发生的7．6级地震(据美国地质调查局)，给印度工业排头兵之一的吉吉拉特邦带来了灾难性的后果。这次地震造成了20,000人死亡，60,000多人受伤，200,000人无家可归，以及20多亿美元的损失。此次地震的震中(23．40°N，70．3... 详细信息

2001年1月26日发生的7．6级地震(据美国地质调查局)，给印度工业排头兵之一的吉吉拉特邦带来了灾难性的后果。这次地震造成了20,000人死亡，60,000多人受伤，200,000人无家可归，以及20多亿美元的损失。此次地震的震中(23．40°N，70．3°E)位于吉吉拉特邦卡奇地区帕焦镇东北10km处。震中深度大约为25km。北部的克什米尔、南部的Kayakumari、东北部的尼泊尔和Calctltta等地对这次地震都有感。

关键词：地震震中美国地质调查局北部深度灾难损失尼泊尔东北

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云南兽类鼩鼱科一新纪录——台湾灰麝鼩

动物学杂志 2017年第5期52卷 865-869页

作者：程峰万韬陈中正 narayan p.asad Koju 何锴蒋学龙中国科学院昆明动物研究所遗传资源与进化国家重点实验室昆明650223 安徽大学健康科学研究院合肥230601

于2006年10月及2015年8月在中国云南省采集到台湾灰麝鼩(Crocidura tanakae Kuroda,1938)3号成体标本。1号雄性与1号雌性的标本来自屏边县大围山自然保护区(22°53′59″N,103°41′23″E,2 088 m),另1号雌性标本采自富宁县里达镇半边箐... 详细信息

于2006年10月及2015年8月在中国云南省采集到台湾灰麝鼩(Crocidura tanakae Kuroda,1938)3号成体标本。1号雄性与1号雌性的标本来自屏边县大围山自然保护区(22°53′59″N,103°41′23″E,2 088 m),另1号雌性标本采自富宁县里达镇半边箐(23°28′11"N,105°35′59″E,1 442 m)。其尾毛长而稀疏,尾长变异大,后足宽大,后足足底和掌外侧垫突出、聚集且呈圆形,这些特征与模式产地的标本吻合。其线粒体Cyt b与地模标本的遗传距离为1.6%。采集地生境为原生林与次生林交界处和落叶季雨林。

关键词：台湾灰麝鼩新纪录云南省动物地理

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