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Dosimetric Analysis of Three Different Radiotherapy Techniques in Patients with Breast Cancer and Their Impact on Organs at Risk (OAR)

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2018年第2期7卷 131-140页

作者： Vikas Jagtap Dimpal Saikia Shashi Bhushan Sharma Shayori Bhattacharjee Moirangthem nara Singh Sachindra Goswami Apurba Kumar Kalita Department of Radiation Oncology North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences Shillong India Department of Radiation Oncology Cancer Hospital Gauhati Medical College Guwahati India Department of Radiation Oncology & Medical Physics Dr. B Borooah Cancer Institute Guwahati India Department of Radiation Oncology American Oncology Institute Nagpur India

Aim: Dosimetric analysis of three different Radiotherapy techniques in patients with Breast Cancer and their impact on OAR’s. Materials and Methods: 12 patients of Carcinoma Breast who received breast radiotherapy were selected for analysis. Computed tomography (CT) simulation image data sets were retrieved. Planning target Volume (PTV), heart and ipsilateral lung were contoured for planning and analysis of doses. Three different plans using conventional bi-tangential fields were prepared, Plan 1 with SAD full beam with wedge (SAD-FBW), Plan 2 with SSD half beam with wedge (SSD-HBW) and plan 3 with SSD half beam without wedge techniques (SSD-HBO) in CMS Xio TPS. Statistical analysis was done using SPSS version 16.0. Results: The PTV coverage was significantly better in SAD-FBW techniques when compared with the other two techniques i.e. SSD-HBW (mean = 92.33, SD = 4.69, p = 0.005) and SSD-HBO (mean = 75.05, SD = 11.92, p = 0.002). The mean heart doses were significantly better in SAD-FBW compared to SSD-HBW (mean = 3.75, SD = 2.27, p = 0.017) but in SSD-HBO technique mean heart doses were better than SAD-FBW technique (mean = 3.27, SD = 1.94, p = 0.004). Similarly, the left lung V20 values were significantly better in SSD-HBO technique than SAD-FBW technique (mean = 11.75, SD = 4.34, p = 0.004) but there was statistically insignificant difference between the SAD-FBW and SSD-HBW techniques. The treatment monitor units were significantly less in SAD-FBW compared to SSD-HBW but SSD-HBO has less MU compared to SAD-FBW technique. Conclusion: SAD Full Beam with wedge technique is practically better than SSD Half Beam technique with or without wedge without compromising PTV coverage considering other dosimetric parameters. We also recommend that centers treating patient with half beam SSD techniques should shift immediately to SAD techniques.

关键词： Breast Radiotherapy Dosimetric Analysis Breast Cancer

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现代喷气变形丝工艺

国外纺织技术(纺织分册) 1984年第9期 26-29页

作者： H.nara 道德锟

1.引言自从1950年Heberlein公司分布了使用上行式加捻器的所谓“加捻—热定型—退捻方法”生产的尼龙长丝的变形丝以来,交形丝的显著特性即膨松性、弹性和均匀度已经在全世界得到广泛的公认。这可由这样的事实所证明:仅仅离那时的几年以... 详细信息

1.引言自从1950年Heberlein公司分布了使用上行式加捻器的所谓“加捻—热定型—退捻方法”生产的尼龙长丝的变形丝以来,交形丝的显著特性即膨松性、弹性和均匀度已经在全世界得到广泛的公认。这可由这样的事实所证明:仅仅离那时的几年以后,在长袜和短袜方面,真丝原料就被尼龙变形丝所代替。

关键词：变形丝衣着纤维长丝变形纱衣物填塞箱复丝

Morphological Structure Characterization of PAH/NiTsPc Multilayer Nanostructured Films

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Materials Sciences and Applications 2011年第11期2卷 1661-1666页

作者： Josmary R. Silva Jackeline B. Brito Sonia T. Tanimoto nara C. de Souza 不详

Morphological structure and growth process of LbL nanostructured films from nickel tetrasulfonated phthalocyanine (NiTsPc) alternated with polyallylamine hydrochloride (PAH) were investigated. The experimental results of UV-visible adsorption kinetics (modeled by Johnson-Mehl-Avrami functions) and AFM images analyzes suggested that the surface morphology structure of films is formed by rod-shaped aggregates produced by a two-step growth process: nucleation and diffusion-limited growth.

关键词： Phthalocyanine Layer-By-Layer Films Growth Processes Adsorption Kinetics

Intraoperative ultrasound as an educational guide for laparoscopic biliary surgery

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World Journal of Gastroenterology 2008年第15期14卷 2370-2376页

作者： Kenichi Hakamada Shunji Narumi Yoshikazu Toyoki Masaki nara Motonari Oohashi Takuya Miura Hiroyuki Jin Syuichi Yoshihara Michihiro Sugai Mutsuo Sasaki Department of Gastroenterological Surgery Hirosaki University Graduate School of Medicine5 Zaifu-choHirosaki 036-8562Japan

AIM: To analyze the efficacy of routine intraoperative ultrasound (IOUS) as a guide for understanding biliary tract anatomy, to avoid bile duct injury (BDI) after laparoscopic cholecystectomy (LC), as well as any burden during the learning period. METHODS: A retrospective analysis was performed using 644 consecutive patients who underwent LC from 1991 to 2006. An educational program with the use of IOUS as an operative guide has been used in 276 cases since 1998. RESULTS: IOUS was highly feasible even in patients with high-grade cholecystitis. No BDI was observed after the introduction of the educational program, despite 72% of operations being performed by inexperienced surgeons. Incidences of other morbidity, mortality, and late complications were comparable before and after the introduction of routine IOUS. However, the operation time was significantly extended after the educational program began (P < 0.001), and the grade of laparoscopic cholecystitis (P = 0.002), use of IOUS (P = 0.01), and the experience of the surgeons (P = 0.05) were significant factors for extending the length of operation. CONCLUSION: IOUS during LC was found to be a highly feasible modality, which provided accurate, real- time information about the biliary structures. Theeducational program using IOUS is expected to minimize the incidence of BDI following LC, especially when performed by less-skilled surgeons.

关键词：胆管损伤胆囊切除术胆汁异常超声外科手术

Gardasil on Twitter: A Content Mining Study Examining Message, Context, and Source Characteristics of Human Papilloma Virus (HPV) Vaccine-Related Tweets

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Health 2020年第9期12卷 1105-1120页

作者： Jessica R. Hawks Atsushi nara Kristen J. Wells John L. Ferrand Eric R. Walsh-Buhi Division of Health Promotion and Behavioral Science School of Public Health San Diego State University San Diego CA USA Department of Geography San Diego State University San Diego CA USA Department of Psychology San Diego State University San Diego CA USA Department of Applied Health Science School of Public Health Indiana University Bloomington Bloomington IN USA

Genital human papilloma virus (HPV) is the most common sexually transmitted virus in the US. Effective HPV vaccines remain controversial and have poor uptake among many adolescent groups. Social media have potential for promoting the HPV vaccine, but little is known about the content or sentiment of social media discussions regarding the vaccine. The purpose of this study was to examine message, context, sentiment, and source characteristics of original HPV- and HPV vaccine-related Twitter posts (tweets) over a 3-month time period. This content mining study used publicly available data purchased from Twitter. One-thousand tweets were randomly selected from a sample of 45,260 English language tweets matching our search criteria and collected from December 2014-January 2015. Tweets were manually coded according to source, context, message, and sentiment characteristics using a coding document developed from previous research. Individuals posted just over half (55%) of tweets, whereas organizations posted 40%. More than half (57%) of all coded tweets were positive, and less than one-fifth were negative. Organizations’ tweets were more likely to be positive than individuals’ tweets. A temporal display of contextual events and tweet spikes demonstrates that positive tweets can increase during newsworthy events (e.g. FDA approval of Gardisil 9). The HPV vaccine was most often discussed under a cancer prevention message frame. In contrast with some existing research, discussions surrounding the HPV vaccine in original Twitter posts are largely positive. Our study reveals opportunities for adolescent health specialists to provide accurate, positive HPV vaccination information via Twitter.

关键词： Papillomavirus Vaccines Twitter Messaging Social Media Information Dissemination Twitter

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量化与地下水水文学

地学工程进展 1998年第2期15卷 70-70,F004页

作者： nara.,TN 孟祥业

Role of hepatectomy for recurrent or initially unresectable hepatocellular carcinoma

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World Journal of Hepatology 2014年第12期6卷 836-843页

作者： Yoji Kishi Kazuaki Shimada Satoshi nara Minoru Esaki Tomoo Kosuge Hepatobiliary and Pancreatic Surgery Division National Cancer Center Hospital Tokyo 104-0045 Japan

As a result of donor shortage and high postoperative morbidity and mortality after liver transplantation,hepatectomy is the most widely applicable and reliable option for curative treatment of hepatocellular carcinoma(HCC).Because intrahepatic tumor recurrence is frequent after loco-regional therapy,repeated treatments are advocated provided background liver function is *** treatments including local ablation and transarterial chemoembolization,hepatectomy provides the best long-term outcomes,but studies comparing hepatectomy with other nonsurgical treatments require careful review for selection *** patients with initially unresectable HCC,transarterial chemo-or radio-embolization,and/or systemic chemotherapy can down-stage the tumor and conversion to resectable HCC is achieved in approximately 20%of ***,complete response is rare,and salvage hepatectomy is essential to help prolong patients’*** counter the short recurrence-free survival,excellent overall survival is obtained by combining and repeating different *** is important to recognize hepatectomy as a complement,rather than a contraindication,to other nonsurgical treatments in a mul-tidisciplinary approach for patients with HCC,including recurrent or unresectable tumors.

关键词： hepatectomy recurrence initially curative complement donor chemotherapy mortality frequent postoperative

Identification and characterization of resistance and pathogenicity of Enterococcus *** samples of donor breast milk

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World Journal of Clinical Pediatrics 2020年第3期9卷 53-62页

作者： Luana Andrade Mendes Santana Nivea nara Novais Andrade Lucas Santana Coelho da Silva Caline Novais Teixeira Oliveira Breno Bittencourt de Brito Fabricio Freire de Melo Claudio Lima Souza Lucas Miranda Marques Marcio Vasconcelos Oliveira Oliveira Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

BACKGROUND Breast milk is the primary source of nutrition for *** babies frequently need nutritional support from Human Milk *** bacterial species of the genus Enterococcus are part of the microbiota of healthy donors,they may contaminate samples of pumped breast *** To identify and characterize the bacterial virulence and resistance in samples isolated from the nipple-areolar region,hands,and breast milk aliquots from donors at the Human Milk Bank of Municipal Hospital EsauMatos in the city of Vitória da Conquista,Bahia State,*** The personal hygiene and sanitation of donors were analyzed with the aim of identifying possible reasons for contamination of pumped *** samples as well as aliquots of unpasteurized and pasteurized milk from 30 participants were *** Enterococcus *** underwent a disk diffusion susceptibility test and molecular biology techniques to determine resistance and virulence *** Enterococcus *** identified in 30%of donors(n=9),and 11 specimens were *** to tetracycline was highly prevalent,being detectable in 63%of the isolates(n=7)and followed by intermediate sensitivity to ciprofloxacin,observed in 27%of the specimens(n=3).The efaA gene was found in 63%(n=7)of the isolates,while the ace gene was detected in 27%(n=3).CONCLUSION This study illustrates the importance of microbiological monitoring by Human Milk Banks and the need for alternatives to prevent the presence of Enterococcus *** hospital settings.

关键词： Enterococcus spp. Breast milk Virulence Human milk Pasteurization Antimicrobial resistanc

Roughness Control of Layer-by-Layer and Alternative Spray Films from Congo Red and PAH via Laser Light Irradiation

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Materials Sciences and Applications 2012年第8期3卷 552-556页

作者： Gleidson Cardoso Romário J.da Silva Rafael R.G.Maciel nara C.de Souza Josmary R.Silva Grupo de Materiais Nanoestruturados Universidade Federal de Mato Grosso Barra do Garcas Brazil

Films from congo red (CR) alternated with poly(allylamine hydrochloride), PAH, were prepared by layer-by-layer and alternative spray techniques. In order to investigate the change of roughness induced by laser light irradiation (532 nm), both kinds of films were characterized by using UV-visible spectroscopy and atomic force microscopy (AFM). At dif- ferent irradiation times, layer-by-layer, LbL, films showed small changes in the roughness and irregular behavior, whereas spray films exhibited higher and a regular decreasing of roughness with increasing irradiation time. The higher roughness of spray films as compared with the LbL ones was attributed to different formation mechanisms of the films. The decreasing of the roughness as a function of the irradiation time (exhibited by the spray films) was associated to surface relaxation due to the interplay between photoisomerization of congo red dye and the heating of the sample during the laser light irradiation. The results suggested that the alternative spray technique is the best choose to control of roughness of the films by using light irradiation.

关键词： Congo Red Poly(Allylamine Hydrochloride) Layer-by-Layer Films Roughness Control Laser Light Irradiation