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Open Journal of Anesthesiology 2018年第7期8卷 223-227页

作者： Aiji Sato naoko Tachi Yoko Okumura Mayumi Hashimoto Masahiro Yamada Tomio Yamada Department of Anesthesiology Aichi Gakuin UniversitySchool of DentistryNagoyaJapan

McGrath? MAC video laryngoscope (McG) has been used for orotracheal intubation in both normal patients and patients for whom intubation was expected to be difficult, and has been reported to provide improved visibility of the glottis during tracheal intubation. There are some reports that normal nasotracheal intubation is easier with McG than with macintosh laryngoscope (ML). The usefulness of McG for nasotracheal intubation is beginning to be recognised. We experienced three cases using McG in patients for whom intubation was expected to be difficult due to the limited mouth opening and using McG for those patients enabled smooth nasotracheal intubation. McG provides good visual field during nasotracheal intubation, and is less invasive to the patient.

关键词： McGrath? MAC Video Laryngoscope Limited Mouth Opening Difficult Intubation Nasotracheal Intubation

Investigation of Patients’ Mood on Their Distance from the Pharmacist during Medication Instruction

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Pharmacology & Pharmacy 2023年第5期14卷 145-155页

作者： Saori Gocho Yukina Miyagi naoko Yamaguchi Chika Nakayama Yuka Miyachi Shoshiro Okada Taeyuki Oshima Department of Pharmacy Nagoya Ekisaikai Hospital Nakagawa Nagoya Aichi Japan Graduate School of Medicine Aichi Medical University Nagakute Aichi Japan College of Pharmacy Kinjo Gakuin University Moriyama Nagoya Aichi Japan Department of Pharmacy Gifu University of Medical Science Kani Gifu Japan

Background: Pharmacists must adjust their distance from patients to facilitate communication during interviews and gain their trust. The distance between the patients and the pharmacists varies depending on many factors, such as gender, posture and the patients’ mood. Only a few of these papers have actually measured and validated distance with patients. In this study, we validated our method of assessing mood and measuring distance before beginning a survey with patients. Methods: We measured comfortable interpersonal distance among men and women using an ecological scenario, in which a pharmacist approaches the subject, and the subject is asked to stop the pharmacist at the distance he/she feel comfortable with. Five pharmacists and 33 subjects participated in the study. The Japanese version of the Brief Mood Questionnaire Checklists (BMC-J) was used to quantify the subject’s mood for the day, and then the distance from the pharmacist that the subjects considered comfortable was measured at the bedside. The relationship between the mood and distance obtained was examined. Results: The comfortable distance of subjects was influenced by gender, posture, and mood. The shortest distance was 94.7 ± 11.1 cm (mean ± SD), for the male subjects versus the female pharmacists in the sitting position. The distance of male subjects shorted when they had positive emotions and lengthened when they were worried. Female subjects maintained a long distance from both male and female pharmacists when they had positive emotions and a short distance when they were worried. Conclusion: Findings show that the distance changes depending on the subjects’ mood at the time of measurement. It was found that the present measurement method can be used to determine the psychological state of the patient and measure the comfort distance at that time, and can be used as a simple method to examine these relationships. Therefore, it is also considered a practical method for the next step, which is a

关键词： Non-Verbal Communication Personal Space Interpersonal Distance Mood Pharmacist

电子产品的生产者责任延伸制和设计革新来自日本和欧洲的例子

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世界环境 2004年第3期 60-61页

作者： naoko Tojo 国际工业环境经济学协会瑞典隆德大学

概述电子产品(EEE)包括了从大型和小型家用电器(冰箱、微波炉、空调、烤面包机和剃须刀等),信息与通信技术(ICT)设备(电话、电脑等)到玩具、照明设备和医疗设备等各种产品.由于电子产品数量越来越多,并且含有有害物质,所以这些产品不能... 详细信息

概述电子产品(EEE)包括了从大型和小型家用电器(冰箱、微波炉、空调、烤面包机和剃须刀等),信息与通信技术(ICT)设备(电话、电脑等)到玩具、照明设备和医疗设备等各种产品.由于电子产品数量越来越多,并且含有有害物质,所以这些产品不能够进行掩埋和焚烧处理.随着技术的高速发展,电子产品的种类也越来越多,这使普通的地方回收站疲于应付.而且回收处理站点不能够从生产商方面得到足够的产品信息,这使得形势更加严峻.而且对于废弃产品不恰当的处理更会导致有用资源的浪费.

关键词：电子产品生产商欧洲产品信息日本浪费资源生产者责任焚烧处理回收处理

The deep-space multi-object orbit determination system and its application to Hayabusa2’s asteroid proximity operations

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Astrodynamics 2020年第4期4卷 377-392页

作者： Hiroshi Takeuchi Kent Yoshikawa Yuto Takei Yusuke Oki Shota Kikuchi Hitoshi Ikeda Stefania Soldini naoko Ogawa Yuya Mimasu Go Ono Fuyuto Terui Naoya Sakatani Manabu Yamada Toru Kouyama Shingo Kameda Takanao Saiki Yuichi Tsuda Institute of Space and A stronautical Science Japan A erospace Exploration AgencySagamihara 252-5210Japan The Graduate University for Aduanced Studies Hayama 240-0193Japan Research and Development Directorate Japan Aerospace Exploration AgencySagamihara 252-5210Japan University of Liverpool Liverpool L693BXUK Chiba Institute of Technology Narashino 275-0016Japan National Institute of Aduanced Industrial Science and Technology Koto-ku 135-0064Japan Rikkyo University Toshima-ku 171-8501Japan

The deep-space multi-object orbit determination system(DMOODS)and its application in the asteroid proximity operation of the Hayabusa2 mission are *** was developed by the Japan Aerospace Exploration Agency(JAXA)for the primary purpose of determining the trajectory of deep-space spacecraft for JAXA’s planetary *** weighted least-squares batch filter is used for the orbit estimator of *** orbit estimator supports more than 10 data types,some of which are used for relative trajectory measurements between multiple space objects including natural satellites and small *** system consists of a set of computer programs running on Linux-based consumer PCs on the ground,which are used for orbit determination and the generation of radiometric tracking data,such as delta differential one-way ranging and doppler tracking *** the asteroid proximity phase of Hayabusa2,this system played an essential role in operations that had very strict navigation requirements or operations in which few optical data were obtained owing to special constraints on the spacecraft attitude or distance from the *** example is orbit determination during the solar conjunction phase,in which the navigation accuracy is degraded by the effect of the solar *** large range bias caused by the solar corona was accurately estimated with DMOODS by combining light detection and ranging(LIDAR)and ranging measurements in the superior solar conjunction phase of *** the orbiting operations of target markers and the MINERVA-II2 rover,the simultaneous estimation of six trajectories of four artificial objects and a natural object was made by *** type of simultaneous orbit determination of multi-artificial objects in deep-space has never been accomplished before.

关键词： orbit determination optical navigation gravity measurements superior solar conjunction delta differential one-way ranging(delta-DOR)

Image-based autonomous navigation of Hayabusa2 using artificial landmarks: The design and brief in-flight results of the first landing on asteroid Ryugu

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Astrodynamics 2020年第2期4卷 89-103页

作者： naoko Ogawa Fuyuto Terui Yuya Mimasu Kent Yoshikawa Go Ono Seiji Yasuda Kota Matsushima Tetsuya Masuda Hiroki Hihara Junpei Sano Takashi Matsuhisa Satoshi Danno Manabu Yamada Yasuhiro Yokota Yuto Takei Takanao Saiki Yuichi Tsuda Japan Aerospace Exploration Agency Sagamihara252-5210Japan NEC Corporation Fuchu183-8501Japan NEC Space Technologies Ltd.Fuchu183-8551Japan Systems Engineering Consultants Co. Ltd.Tokyo158-0097Japan Planetary Exploration Research Center Chiba Institute of TechnologyNarashino275-0016Japan

Hayabusa2 is an asteroid sample return mission carried out by the Japan Aerospace Exploration *** spacecraft was launched in 2014 and arrived at the target asteroid Ryugu on June 27,*** the 1.5-year proximity phase,several critical operations(including two landing/sampling operations)were successfully *** were based on autonomous image-based descent and landing *** paper describes an imagebased autonomous navigation scheme of the Hayabusa2 mission using artificial landmarks named target markers(TMs).Its basic algorithm,and the in-flight results of the first touchdown and its rehearsal,are shown.

关键词： Hayabusa2 Ryugu image-based navigation target marker tracking

Enhanced Surveillance for National (Handicapped) Sports Games in Wakayama, Japan 2015

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Journal of Biosciences and Medicines 2018年第7期6卷 35-47页

作者： Chisa Kambe Hiroko Fujii Tetsuya Niu Hideo Matsuura naoko Nagai Yuuki Nakamura Takako Nojiri Wakayama City Public Health Center Wakayama Japan Graduate School of Pharmacy Nihon University Chiba Japan Wakayama Prefecture Health Department Wakayama Japan

Introduction: We undertook enhanced surveillance of the 2015 Kinokuni Wakayama National Sports Games (70th National Sports Games) and the Kinokuni Wakayama Handicapped Sports Games (15th National Handicapped Sports Games) held in Wakayama prefecture in 2015, for which this paper presented operational details and an evaluation. Methods: Enhanced surveillance conducted involved (Nursery) School Absenteeism Surveillance system ((N)SASSy), Prescription Surveillance, and Ambulance Transfer Surveillance from 30 August through 9 November. We evaluated those surveillances on all days including weekends, integrated the results as a daily report, and published it on the web. Results: We found no cluster or cases requiring more tracing and investigation except for suspected cases of rubella in (N)SASSy. Moreover, no moderate aberration was found for two consecutive days for the same area and symptom. Conclusion: Our experience with this enhanced surveillance presents important lessons for countermeasures by local governments for mass gatherings or politically important events.

关键词： Enhanced Surveillance National (Handicapped) Sports Games Mass-Gathering Event (Nursery) School Absenteeism Surveillance System Prescription Surveillance Ambulance Transfer Surveillance

Role of Mash Ⅰ in Lung Growth and Differentiation using Mash Ⅰ Defictent Mice

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Role of Mash Ⅰ in Lung Growth and Differentiation using Mas...

Risk of alcohol use relapse after liver transplantation for alcoholic liver disease

Third Congress of the Asian-Pacific Organization for Cell Biology

作者： naoko UDAKA Takaaki ITO Takayuki IKOMA Hitoshi KITAMURA Ryoichiro KAGEYAMA Pathol. Division Kanagawa Cardiovascular Respiratory Center6-16-1 TomiokahigashiKana/awa-kuYokohama Dept of Pathol. Yokohama City Univ Sch of Medicine3-9 FukuuraKanazawa-kuYokohama Institute for Virus Research.kyoto Univ. 53 Shougoin KawaramachiSakyou-kuKyotoJAPAN

In vertebrates,a basic helix-loop-helix transcription factor that is homologous to the Drosophila achaete-scute complex plays a critical role in the development and differentiation in neural cells and neuroendocrine cells. In the lung, pulumonary neuroendoerine cells(PNEC) are distributed throughout the intraplumonary airway Trom the large bronehi to the alveolar duets, which occur

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World Journal of Gastroenterology 2017年第5期23卷 869-875页

作者： Yasuharu Onishi Hiroyuki Kimura Tomohide Hori Shinichi Kishi Hideya Kamei Nobuhiko Kurata Chisato Tsuboi naoko Yamaguchi Mayu Takahashi Saki Sunada Mitsuaki Hirano Hiroshige Fujishiro Takashi Okada Masatoshi Ishigami Hidemi Goto Norio Ozaki Yasuhiro Ogura Department of Transplantation Surgery Nagoya University Hospital Department of Psychiatry Nagoya University Hospital Transplant Coordination Service Nagoya University Hospital Department of Gastro-enterology and Hepatology Nagoya University Graduate School of Medicine

AIMTo investigate factors, including psychosocial factors, associated with alcoholic use relapse after liver transplantation (LT) for alcoholic liver disease (ALD).METHODSThe clinical records of 102 patients with ALD who were referred to Nagoya University Hospital for LT between May 2003 and March 2015 were retrospectively evaluated. History of alcohol intake was obtained from their clinical records and scored according to the High-Risk Alcoholism Relapse scale, which includes duration of heavy drinking, types and amount of alcohol usually consumed, and previous inpatient treatment history for alcoholism. All patients were assessed for eligibility for LT according to comprehensive criteria, including Child-Pugh score, Model for End-Stage Liver Disease score, and psychosocial *** the 102 patients with ALD referred for LT, seven (6.9%) underwent LT. One (14.3%) of these seven patients returned to heavy drinking, but that patient was able to successfully quit drinking following an immediate intervention, consisting of psychotherapeutic education and supportive psychotherapy, by a psychiatrist. A comparison between the transplantation/registration (T/R) group, consisting of the seven patients who underwent LT and 10 patients listed for deceased donor LT, and 50 patients who did not undergo LT and were not listed for deceased donor LT (non-T/R group), showed statistically significant differences in duration of abstinence period (P < 0.01), duration of heavy drinking (P < 0.05), adherence to medical treatment (P < 0.01), and declaration of abstinence (P < 0.05).CONCLUSIONPatients with ALD referred for LT require comprehensive evaluation, including evaluation of psychosocial criteria, to prevent alcoholic recidivism.

关键词： Liver transplantation Risk assessment Alcoholic liver disease Psychosocial evaluation criteria Liaison psychiatry Alcohol use relapse

Modulation of HPV-infected Cell Proliferation and Invasion by Ras Protein

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Modulation of HPV-infected Cell Proliferation and Invasion b...

ANTITUMOR ACTIVITIES AND TUMOR NECROSIS FACTOR PRODUCIBILITY OF TRADITIONAL CHINESE MEDICINES AND CRUDE DRUGS

24th International Papillomavirus Conference and Clinical Workshop

作者： Satoshi Yoshida naoko Kajitani Ayano Satsuka Hiroyasu Nakamura Hiroyuki Sakai Institute for Virus Reseach Kyoto University Institute for Virus Reseach Kyoto University Institute for Virus Reseach Kyoto University Institute for Virus Reseach Kyoto University Institute for Virus Reseach Kyoto University

＜正＞HPVs are associated with more than 90% of all human cervical *** two viral proteins,E6 and E7,which binds to and degrades p53 and pRb respectively,are considered as main factors of the HPV-induced tumorigenesis .However,it is understood that HPV infection alone is not sufficient for cancer formation Cervical carcinogenesis is considered as the multi-

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Journal of Traditional Chinese Medicine 1985年第4期5卷 271-278页

作者： Katsuyuki Haranaka Nobuko Satomi Akiko Sakurai Ruriko Haranaka naoko Okada Hiroshi Kosoto Mosaburo Kobayashi Department of Biochemistry 4-6-1 Shirokanedai Itabashi-ku Tokyo 173 Department of Internal Medicine Institute of Medical Science 30-1 Japan Tokyo 108 University of Tokyo Nihon University School of Medicine Minato-ku Ohyaguchi-Kamimachi

The antitumor activities and tumor necrosis fac-tor(TNF)producibility of traditional Chinese herbalpreparations(Zhu-ling-tang,Xiao-chai-hu-tang,Wu-ling-san,Bu-zhong-yi-qi-tang and Shi-quan-da-bu-tang),crode drugs(Polyporos,Hoelen,Bupleuri Radix,An-gelica Radix,Cnidii Rhizoma,Cinnamomum Cortex,Pinelliae Tuber)and Krestin(PSK)were investigatedusing *** drugs were given to DDY micein the drinking water before and after transplanta-tion of Ehrlich tumors,and the development of theintradermally transplanted Ehrlich tumors and sur-vival rate were observed.A high survival rate andgood inhibition of transplanted Ehrlich tumors wereobserved in the groups administered Bupleuri Radix,Angelica Radix,Cinnamomum Cortex or ***-tang,while the group given Hoelen showed *** examine the TNF producibility,thesedrugs were given to DDY mice orally as first stimu-lating agents to stimulate the reticuloendothelialsystem(RES),prior to lipopolysaccharide *** TNF activity was tested by the cytotoxicityagainst L *** differences in TNF pro-ducibility were observed among the ***-tively high levels of TNF activity were noted in thegroups given Angelica Radix,Bupleuri Radix,Cinna-momum Cortex or Cnidii Rhizoma,very low activi-ties in the groups given Xiao-chai-hu-tang,Zhu-ling-tang,Wu-ling-san,Bu-zhong-yi-qi-tang,Shi-quan-da-bu-tang or Krestin and no TNF activities in thegroups given Polyporus,Hoelen or Pinelliae *** TNF producibility broadly paralleled the degreeof survival rate in the mice transplanted with Ehr-lich *** on our findings,it is consideredthat one mechanism underlying the antitumor acti-vities of these drugs is the stimulation of the RESand TNF is produced as the result of mitotic RESstimulation and activation.

关键词： In ANTITUMOR ACTIVITIES AND TUMOR NECROSIS FACTOR PRODUCIBILITY OF TRADITIONAL CHINESE MEDICINES AND CRUDE DRUGS TNF