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Glycylproline dipeptidyl aminopeptidase isoenzyme in diagnosis of primary hepatocellular carcinoma

World Journal of Gastroenterology 2003年第4期9卷 710-713页

作者： Run-Zhou Ni Jie-Fei Huang Ming-Bing Xiao Mei Li Xian-Yong Meng Department of Gastroenterology,Affiliated Hospital of nantong Medical college,nantong 226001,Jiangsu Province,china Department of Gastroenterology Affiliated Hospital of Nantong Medical College Nantong 226001 Jiangsu Province China. nirz@***

AIM: To investigate the role of glycylproline dipeptidyl aminopeptidase (GPDA) isoenzyme in the diagnosis of primary hepatocellular carcinoma (PHC), especially in patients with negative alpha-fetoprotein (AFP).METHODS: A stage gradient polyacrylamide gel discontinuous electrophoresis system was developed to separate serum GPDA isoenzymes, which were determined in 102 patients with PHC, 45 cases with liver cirrhosis, 24cases with chronic hepatitis, 35 cases with benign liver spaceoccupying lesions, 20 cases with metastatic liver cancer and 50 cases with extra-hepatic cancer, as well as 80 healthy subjects. The relationships between GPDA isoenzymes and AFP, the sizes of tumors, as well as alanine aminotransferase (ALT) were also ***: Serum GPDA was separated into two isoenzymes,GPDA-S and GPDA-F. The former was positive in all subjects,while the latter was found mainly in majority of PHC (85.3 %)and a few cases with liver cirrhosis (11.1%), chronic hepatitis (33.3 %), metastatic liver cancer (15.0 %) and non-hepatic cancer (16.0 %). GPDA-F was negative in all healthy subjects and patients with benign liver space-occupying lesions,including abscess, cysts and angioma. There was no correlation between GPDA-F and AFP concentration or tumor size. GPDA-F was consistently positive and not correlated with ALT in PHC, but GPDA-F often converted to negative as decline of ALT in benign liver diseases. The electrophoretic migration of GPDA-F became sluggish after the treatment of ***: GPDA-F is a new useful serum marker for PHC. Measurement of serum GPDA-F is helpful in diagnosis of PHC, especially in patients with negative AFP. GPDA-F is one kind of glycoproteins rich in sialic acid.

关键词：原发性肝细胞癌肿瘤标志物早期诊断 GPDA α-胎蛋白同工酶丙氨酸转氨酶

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美国高校创业教育的动因及特点探析

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外国教育研究 2007年第3期34卷 62-65页

作者：季学军南通大学教育科学学院江苏南通226007

历经半个多世纪的发展,美国高校创业教育业已形成了较为完善的体系结构,且在领导力量、师资配备、课程建设、组织机构以及评价机制诸方面形成了自身的特色。文章在阐述美国创业教育的动因与特点的基础上,结合我国目前创业教育的现状,围... 详细信息

历经半个多世纪的发展,美国高校创业教育业已形成了较为完善的体系结构,且在领导力量、师资配备、课程建设、组织机构以及评价机制诸方面形成了自身的特色。文章在阐述美国创业教育的动因与特点的基础上,结合我国目前创业教育的现状,围绕创业教育的理念、师资队伍建设、创业实践体验、中外合作交流诸方面提出些许建议。

关键词：美国高校创业教育动因特点

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婴童家用纺织品设计与生产

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上海纺织科技 2009年第10期37卷 46-47页

作者：姜淑媛贾欢南通纺织职业技术学院设计艺术系江苏南通226007

中国婴童家纺市场比较薄弱,婴童床品是整个市场最薄弱的部分,需要大力开发,以满足消费者的需求。婴童家用纺织品的设计应该从舒适、卫生、环保、适应于儿童生长发育等多方面考虑。文章介绍了一款婴童用床品的设计流程及加工工艺。指出... 详细信息

中国婴童家纺市场比较薄弱,婴童床品是整个市场最薄弱的部分,需要大力开发,以满足消费者的需求。婴童家用纺织品的设计应该从舒适、卫生、环保、适应于儿童生长发育等多方面考虑。文章介绍了一款婴童用床品的设计流程及加工工艺。指出随着社会经济水平和人民生活水平的提高,婴童家纺用品会在未来家纺市场中占有更重要的地位。

关键词：纺织品床上用品设计流程生产

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康有为的学校体育思想

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体育科学 2004年第3期24卷 64-66页

作者：何叙南通师范学院体育系江苏南通226007

康有为的学校体育思想是其教育思想的重要组成部分 ,康有为在中国首倡德、智、体全面发展 ;根据不同年龄阶段教育的特点 ,来确定体育的地位与内容 ;重视儿童的健康教育。

关键词：康有为学校体育思想

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Existence of Almost Resolvable Directed 7-Cycle Systems

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Journal of Shanghai Jiaotong University 2005年第3期10 E卷 318-321页

作者：王金华苏仁旺 School of Sciences nantong Univ. nantong 2.6007 china college of Statistics and Computing Science Zhejiang Gongshang Univ. Hangzho u 310035

Let ARDkCS(v) denote an almost resolvable directed k-cycle system of order v. It is clear that a necessary condition for the existence of an ARD kCS(v) is v≡1(mod k). For k=3,4,5 and 6, the existence of an ARDkCS(v) ... 详细信息

关键词： directed k-cycle system group divisible directed k-cycle system almo st resolvable

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