In this manuscript,we provide critical commentary on the systematic review by Augustin et al,which investigated acute pancreatitis induced by primary hyperparathyroidism during *** this is an infrequent complication,i...
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In this manuscript,we provide critical commentary on the systematic review by Augustin et al,which investigated acute pancreatitis induced by primary hyperparathyroidism during *** this is an infrequent complication,it poses severe risks to both maternal and fetal *** to its infrequent occurrence in clinical practice,this review is based on an analysis of individual case reports over the past 55 *** this is not the first study to utilize this sampling method for primary hyperparathyroidism-induced acute pancreatitis,it is unique in that it has a sufficiently large sample size with statistically significant *** discussion focuses on the diagnostic challenges associated with this condition,which are grounded in the mechanisms of parathyroid hormone secretion and variations in serum calcium *** also address the limitations of the current review and suggest potential strategies to increase diagnostic accuracy and improve health outcomes for both mothers and fetuses during pregnancy.
This article explores the integration of Eastern and Western perspectives on the use of dexamethasone and N-acetylcysteine as premedications in transarterial chemoembolization for hepatocellular carcinoma(HCC).By exam...
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This article explores the integration of Eastern and Western perspectives on the use of dexamethasone and N-acetylcysteine as premedications in transarterial chemoembolization for hepatocellular carcinoma(HCC).By examining key concerns raised by Western researchers,particularly regarding the different etiologies of liver cirrhosis,and contrasting them with robust clinical data from Asia,this article highlights the necessity for region-specific research and proposes future directions for global HCC management.
Determination of Shear Bond strength(SBS)at interlayer of double-layer asphalt concrete is crucial in flexible pavement *** study used three Machine Learning(ML)models,including K-Nearest Neighbors(KNN),Extra Trees(ET...
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Determination of Shear Bond strength(SBS)at interlayer of double-layer asphalt concrete is crucial in flexible pavement *** study used three Machine Learning(ML)models,including K-Nearest Neighbors(KNN),Extra Trees(ET),and Light Gradient Boosting Machine(LGBM),to predict SBS based on easily determinable input ***,the Grid Search technique was employed for hyper-parameter tuning of the ML models,and cross-validation and learning curve analysis were used for training the *** models were built on a database of 240 experimental results and three input variables:temperature,normal pressure,and tack coat *** validation was performed using three statistical criteria:the coefficient of determination(R2),the Root Mean Square Error(RMSE),and the mean absolute error(MAE).Additionally,SHAP analysis was also used to validate the importance of the input variables in the prediction of the *** show that these models accurately predict SBS,with LGBM providing outstanding ***(Shapley Additive explanation)analysis for LGBM indicates that temperature is the most influential factor on ***,the proposed ML models can quickly and accurately predict SBS between two layers of asphalt concrete,serving practical applications in flexible pavement structure design.
This study was aimed to prepare landslide susceptibility maps for the Pithoragarh district in Uttarakhand,India,using advanced ensemble models that combined Radial Basis Function Networks(RBFN)with three ensemble lear...
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This study was aimed to prepare landslide susceptibility maps for the Pithoragarh district in Uttarakhand,India,using advanced ensemble models that combined Radial Basis Function Networks(RBFN)with three ensemble learning techniques:DAGGING(DG),MULTIBOOST(MB),and ADABOOST(AB).This combination resulted in three distinct ensemble models:DG-RBFN,MB-RBFN,and ***,a traditional weighted method,Information Value(IV),and a benchmark machine learning(ML)model,Multilayer Perceptron Neural Network(MLP),were employed for comparison and *** models were developed using ten landslide conditioning factors,which included slope,aspect,elevation,curvature,land cover,geomorphology,overburden depth,lithology,distance to rivers and distance to *** factors were instrumental in predicting the output variable,which was the probability of landslide *** analysis of the models’performance indicated that the DG-RBFN model,with an Area Under ROC Curve(AUC)of 0.931,outperformed the other *** AB-RBFN model achieved an AUC of 0.929,the MB-RBFN model had an AUC of 0.913,and the MLP model recorded an AUC of *** results suggest that the advanced ensemble ML model DG-RBFN was more accurate than traditional statistical model,single MLP model,and other ensemble models in preparing trustworthy landslide susceptibility maps,thereby enhancing land use planning and decision-making.
Cost-effective CO_(2) adsorbents are gaining increasing attention as viable solutions for mitigating climate *** this study,composites were synthesized by electrochemically combining the post-gasification residue of M...
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Cost-effective CO_(2) adsorbents are gaining increasing attention as viable solutions for mitigating climate *** this study,composites were synthesized by electrochemically combining the post-gasification residue of Macadamia nut shell with copper benzene-1,3,5-tricarboxylate(CuBTC).Among the different composites synthesized,the ratio of 1:1 between biochar and CuBTC(B 1:1)demonstrated the highest CO_(2) adsorption *** controlled laboratory conditions(0°C,1 bar,without the influence of ambient moisture or CO_(2) diffusion limitations),B 1:1 achieved a CO_(2) adsorption capacity of 9.8 mmol/g,while under industrial-like conditions(25℃,1 bar,taking into account the impact of ambient moisture and CO_(2) diffusion limitations within a bed of adsorbent),it reached 6.2 mmol/*** values surpassed those reported for various advanced CO_(2) adsorbents investigated in previous *** superior performance of the B 1:1 composite can be attributed to the optimization of the number of active sites,porosity,and the preservation of the full physical and chemical surface properties of both ***,the composite exhibited a notable CO_(2)/N_(2) selectivity and improved stability under moisture *** favorable characteristics make B 1:1 a promising candidate for industrial applications.
User profiles representing users’preferences and interests play an important role in many applications of personalized *** the rapid growth of social platforms,there is a critical need for efficient solutions to lear...
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User profiles representing users’preferences and interests play an important role in many applications of personalized *** the rapid growth of social platforms,there is a critical need for efficient solutions to learn user profiles from the information they shared on social platforms so as to improve the quality of recommendation *** problem of user profile learning is significantly challenging due to difficulty in handling data from multiple sources,in different formats and often associated with *** this paper,we introduce an integrated approach that combines advanced Machine Learning techniques with evidential reasoning based on Dempster-Shafer theory of evidence for user profiling and *** developed methods for user profile learning and multi-criteria collaborative filtering are demonstrated with experimental results and analysis that show the effectiveness and practicality of the integrated approach.A proposal for extending multi-criteria recommendation systems by incorporating user profiles learned from different sources of data into the recommendation process so as to provide better recommendation capabilities is also highlighted.
BACKGROUND Tacrolimus(TAC)is metabolized primarily by the CYP3A-encoded enzyme family(CYP3A4,CYP3A5,and CYP3A7).Individuals expressing the CYP3A51 allele are considered fast metabolizers and generally require higher T...
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BACKGROUND Tacrolimus(TAC)is metabolized primarily by the CYP3A-encoded enzyme family(CYP3A4,CYP3A5,and CYP3A7).Individuals expressing the CYP3A51 allele are considered fast metabolizers and generally require higher TAC doses to reach therapeutic *** To evaluate the predictive value of the TAC concentration-to-dose(C0/D)ratio for identifying CYP3A5 poly-morphisms in renal transplant *** Eighty-six de novo kidney transplant recipients with TAC-based immunosuppression from the Department of Nephrology and Dialysis at Military Hospital 103(Hanoi,Vietnam)were included in this retrospective *** samples were collected within the first week post-transplantation to monitor TAC levels and to perform genotyping for CYP3A5 genetic *** The CYP3A53/3 genotype was identified in 37 patients(43%),CYP3A51/3 in 40 patients(46.5%),and CYP3A51/1 in 9 patients(10.5%).Patients carrying the CYP3A51/3 or CYP3A51/1 genotype,classified as fast metabolizers(CYP3A5 expressers),had significantly lower TAC C0 concentrations and C0/D ratios compared to slow meta-bolizers(CYP3A53/3 genotype)at multiple time points during follow-up(all Pnam and other low-income countries.
We present a photodiode-based Chua's chaotic circuit that is controllable by light. The proposed circuit consists of an inductor, two passive capacitors, a photodiode-based variable resistor, and a positive feedback ...
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We present a photodiode-based Chua's chaotic circuit that is controllable by light. The proposed circuit consists of an inductor, two passive capacitors, a photodiode-based variable resistor, and a positive feedback trans- conductor with negative nonlinearity. The chaotic dynamics of the circuit were verified by using the simulation program with integrated circuit emphasis analysis using the 0.35 #m complementary metal-oxide-semiconductor process parameters. The gain results (such as the time waveform~ frequency analysis, three-dimensional attractor, bifurcation and Lyapunov exponents diagrams) confirm that the chaotic behavior of the circuit could be controlled by light intensity via the photodiode-based variable resistor.
Due to the rapid industrialization and the development of the economy in each country,the demand for energy is increasing *** coal mines have to pace up the mining operations with large production to meet the energy *...
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Due to the rapid industrialization and the development of the economy in each country,the demand for energy is increasing *** coal mines have to pace up the mining operations with large production to meet the energy *** requirement has led underground coal mines to go deeper with more difficult conditions,especially the mining hazards,such as large deformations,rockburst,coal burst,roof collapse,to name a ***,this study aims at investigating and predicting the stability of the roadways in underground coal mines exploited by longwall mining method,using various novel intelligent techniques based on physics-based optimization algorithms(***-verse optimizer(MVO),equilibrium optimizer(EO),simulated annealing(SA),and Henry gas solubility optimization(HGSO)) and adaptive neuro-fuzzy inference system(ANFIS),named as MVO-ANFIS,EO-ANFIS,SA-ANFIS and HGSOANFIS ***,162 roof displacement events were investigated based on the characteristics of surrounding rocks,such as cohesion,Young’s modulus,density,shear strength,angle of internal friction,uniaxial compressive strength,quench durability index,rock mass rating,and tensile *** MVO-ANFIS,EO-ANFIS,SA-ANFIS and HGSO-ANFIS models were then developed and evaluated based on this dataset for predicting roof displacements in roadways of underground *** results indicated that the proposed intelligent techniques could accurately predict the roof displacements in roadways of underground mines with an accuracy in the range of 83%-92%.Remarkably,the SA-ANFIS model yielded the most dominant accuracy(i.e.92%).Based on the accurate predictions from the proposed techniques,the reinforced solutions can be timely suggested to ensure the stability of roadways during exploiting coal,especially in the underground coal mines exploited by the longwall mining.
OBJECTIVE:To evaluate the efficacy of bee venom acupuncture in humeroscapularis(PHS)***:One hundred and twenty patients diagnosed with PHS were assigned into four groups:BV1(0.01 mg/kg),BV2(0.005 mg/kg),BV3(0.0025 mg/...
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OBJECTIVE:To evaluate the efficacy of bee venom acupuncture in humeroscapularis(PHS)***:One hundred and twenty patients diagnosed with PHS were assigned into four groups:BV1(0.01 mg/kg),BV2(0.005 mg/kg),BV3(0.0025 mg/kg),and control group(vitamin B1 plus novocain 3%injection)with 15 d of *** outcomes of the study including visual analogue scale(VAS)score andβ-endorphin,inflammatory cytokines including interleukin-10(IL-10),IL-1βand tumor necrosis factorα(TNF-α)and shoulder function score were assessed at baseline,after 10 and 15 d of ***:All four groups reported statistically significant improvement in VAS score,motion range,and shoulder function score(Pduced pain,improved motor function and normalized inflammatory cytokines than current therapy used in Vietnam and other groups.
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