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BIOCELL 2019年第2期43卷 81-87页

作者： MAHMOUD MOUSTAFA SAAD ALAMRI HOIDA ZAKI naglaa loutfy TAREK TAHA ALI SHATI MOHAMED ALKAHTANI SAJDA SIDDIQI Department of Biology College of ScienceKing Khalid University9004AbhaKingdom of Saudi Arabia(KSA) Department of Botany Faculty of ScienceSouth Valley UniversityQenaEgypt Environmental Biotechnology Department Genetic Engineering and Biotechnology Research Institute(GEBRI)City of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab City21934AlexandriaEgypt

The present research reports of quick and marked changes induced by plant extract of Euryops arabicus in the gene expression of 49-kDa apyrases,cytoskeletal proteins,ATPases,ADPase and amount of amino acid of pea(Pisum sativum ***).Pellets of cytoskeletals proteins(27000 xg)were probed with anti-apyrase antibody,biotinylated anti-rat,actin and alpha and beta-tubulin for Western *** and ADPase activities were determined based on the hydrolytic efficacy of adenine triphosphate and adenine *** 72 hours,the abundance of apyrases,cytoskeletal proteins and amount of amino acid in pellets of 27000 xg of germinated pea seeds in *** extracts were sharply increased than those sown in distilled *** the samples exhibited that the stems had more amount from apyrases,cytoskeletal proteins,amino acids and ATPase and ADPase activities than primary leaves and primary roots that were germinated either on *** water extract or in distilled *** on the enzyme’s capability to hydrolyse nucleotide triphosphate and nucleotide diphosphate as well as the direct association between expression of 49-kDa apyrase and cytoskeletal proteins,*** water extract had an important effect on plant germinations.

关键词： Cytoskeletal proteins ATPase ADPase Pisum sativum Euryops arabicus

Wood By-Products as UV Protection:A Consequence Review

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Journal of Renewable Materials 2024年第4期12卷 699-720页

作者： naglaa Salem El‑Sayed Mohamed Hasanin Samir Kamel Cellulose and Paper Department National Research CentreCairo12622Egypt

In recent decades,the ozone layer has suffered considerable damage,increasing the entry of ultraviolet(UV)light into the atmosphere and reaching the earth’s surface,negatively affecting ***,researchers aimed to solve this problem by synthesizing advanced UV-shielding *** the other hand,developing an easy and green strategy to prepare functional materials with outstanding properties based on naturally abundant and environmentally friendly raw materials is highly desirable for sustainable *** biomass-derived materials are sustainable and biodegradable,they present a promising substitute for petroleum-based *** three main structural constituents of the plant biomass-based materials that are naturally available are cellulose,hemicellulose,and *** review details current developments using wood-based products such as cellulose,hemicellulose,and lignin in UV-shielding *** will start with assembling the structure and chemistry of cellulose,hemicellulose,and lignin,followed by their contributions to preparing UV-shielding ***,it will briefly discuss the different processing methods for the design of UV-shielding *** wood by-products offer additional opportunities to use the whole tree harvest.

关键词： UV-shielding wood cellulose lignin hemicellulose sunlight protection

Bone marrow microRNA-34a is a good indicator for response to treatment in acute myeloid leukemia

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Oncology Research 2024年第3期32卷 577-584页

作者： MONA SA BDELLATEIF naglaa MHASSAN MAHMOUD MKAMEL YOMNA MEL-MELIGUI Department of Cancer Biology Medical Biochemistry and Molecular BiologyNational Cancer InstituteCairo UniversityCairo11976Egypt Department of Cinical Pathology National Cancer InstituteCairo UniversityCairo11976Egypt

Background:microRNA 34a(miR 34a)had been reported to have a diagnostic role in acute myeloid leukemia(AML).However,its value in the bone marrow(BM)of AML patients,in addition to its role in response to therapy is still *** current study was designed to assess the diagnostic,prognostic,and predictive significance of miR 34a in the BM of AML ***:The miR.34a was assed in BM aspirate of 82 AML patients in relation to 12 normal control subjects using *** data were assessed for correlation with the relevant dinical critenia,response to therapy,disease-free survival(DFS),and overall survival(OS)***:miR.34a was significantly downregulated in AML patients[0.005(3.3×10^(-6)-1.32)],compared to the control subjects[0.108(3.2× 10^(-4)-1.64),p=0.021].*** relative quantification(RQ)of miR-34a was 0.106(range;0-32.12).The specifaity,sensitivity,and area under the curve(AUC)for the diagnosis of AML were(58.3%,69.5%,0.707,respectively,p=0.021).patients with upregulated miR-34a showed decreased platelets count<34.5 × 10^(9)/L,and achieved early complete remission(CR,p=0.031,p=0.044,respectively).Similarly,patients who were refractory to therapy showed decreased miR 34a levels in comparison to those who achieved CR[0.002(0-0.01)and 0.12(0-32.12),respectively,p=0.002].Therefore,miR 34a could significantly identify patients with CR with a specificity of 75%and sensitivity of 100%at a cut-off of 0.014(AUC=0.927,p=0.005).There was no considerable association between miR-34a expression and survival rates of the induded AML ***:miR-34a could be a beneficial diagnostic biomarker for AML *** addition,it serves as a good indicator for response to therapy,which could possibly identify patients who are refractory to treatment with 100%sensitivity and 75%specificity.

关键词： AML miR 34a microRNA Leukemia

Green retrofitting of heritage buildings based on(3Ts)framework:An applied case study

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Frontiers of Architectural Research 2024年第4期13卷 776-798页

作者： Alaa O.Shehata Asmaa M.Hassan Merhan M.Shahda naglaa A.Megahed Architectural Engineering and Urban Planning Department Faculty of EngineeringPort Said UniversityPort SaidEgypt

Diverse heritage architecture characterizes Port Said in Egypt,reflecting European and Arab *** Canal heritage villas comprise 25%of the total listed heritage buildings in the ***,it is important to retrofit them,aligning with the Sustainable Development Goals(SDGs).By reviewing the previous literature related to the green retrofitting of heritage buildings,the(3Ts)framework can be considered a holistic framework that covers the latest trends due to its three components:targets,tools,and tasks,which help the success of the process through a holistic vision of supporting building information modeling(BIM)technologies and organizing stakeholders’*** paper aims to apply the(3Ts)framework to Suez Canal heritage villas in Port Said,*** applied study is based on how stakeholders perceive their input and decision-making,measuring the climate parameters,proposing several green retrofits,and integrating them into green *** of scenarios is conducted by utilizing the Design Builder simulation ***,the Skelion plugin calculates the photovoltaic system’s(PVs)energy *** results indicated that the total energy savings could reach approximately 12%e74%and nearly 10%e73%CO₂emissions reduction without affecting heritage values.

关键词： Green retrofitting Heritage buildings BIM BES Suez Canal heritage villas Port Said/Egypt

A Hybrid Cybersecurity Algorithm for Digital Image Transmission over Advanced Communication Channel Models

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Computers, Materials & Continua 2024年第4期79卷 201-241页

作者： naglaa F.Soliman Fatma E.Fadl-Allah Walid El-Shafai Mahmoud I.Aly Maali Alabdulhafith Fathi E.Abd El-Samie Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Electronics and Communications Faculty of EngineeringZagazig UniversityZagazig44519Egypt Security Engineering Lab Computer Science DepartmentPrince Sultan UniversityRiyadh11586Saudi Arabia Department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt

The efficient transmission of images,which plays a large role inwireless communication systems,poses a significant challenge in the growth of multimedia ***-quality images require well-tuned communication *** Single Carrier Frequency Division Multiple Access(SC-FDMA)is adopted for broadband wireless communications,because of its low sensitivity to carrier frequency offsets and low Peak-to-Average Power Ratio(PAPR).Data transmission through open-channel networks requires much concentration on security,reliability,and *** data need a space away fromunauthorized access,modification,or *** requirements are to be fulfilled by digital image watermarking and *** paper ismainly concerned with secure image communication over the wireless SC-FDMA systemas an adopted communication *** introduces a robust image communication framework over SC-FDMA that comprises digital image watermarking and encryption to improve image security,while maintaining a high-quality reconstruction of images at the receiver *** proposed framework allows image watermarking based on the Discrete Cosine Transform(DCT)merged with the Singular Value Decomposition(SVD)in the so-called DCT-SVD *** addition,image encryption is implemented based on chaos and DNA *** encrypted watermarked images are then transmitted through the wireless SC-FDMA *** linearMinimumMean Square Error(MMSE)equalizer is investigated in this paper to mitigate the effect of channel fading and noise on the transmitted *** subcarrier mapping schemes,namely localized and interleaved schemes,are compared in this *** study depends on different channelmodels,namely PedestrianAandVehicularA,with a modulation technique namedQuadratureAmplitude Modulation(QAM).Extensive simulation experiments are conducted and introduced in this paper for efficient transmission of encrypted watermarked *** addition,different variants of SC-FDMA bas

关键词： Cybersecurity applications image transmission channel models modulation techniques watermarking and encryption

Correlation between DKK-1 Level and Bone Density Status in Children on Maintenance Haemodialysis

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Open Journal of Nephrology 2024年第1期14卷 48-61页

作者： Manal Abd El-Salam Marwa Mohamed Anwar Rasha Mahmoud Gouda naglaa Abou El Fattah Nadia Youssef Riad Department of Pediatrics Faculty of Medicine (For Girls) Al-Azhar University Cairo Egypt Department of Internal Medicine Faculty of Medicine (For Girls) Al-Azhar University Cairo Egypt Department of Clinical Pathology National Heart Institute Cairo Egypt

Background: Renal osteodystrophy (ROD) is a bone disorder resulting from chronic kidney disease (CKD) and related metabolic diseases. Dickkopf-related protein-1 (DKK-1) is critical in regulating bone biology. This study aimed to evaluate the serum DKK-1 level as a bone marker in children with CKD who undergo regular hemodialysis (HD). Subjects and Methods: This case-control study involved 40 children with CKD on HD and 40 healthy children as controls. The study measured serum DKK-1 levels and performed a dual-energy X-ray absorptiometry scan (DEXA) in line with routine laboratory investigations. Results: There was a significant increase in the serum level of DKK-1 in the patient group compared to the control group. The DKK-1 levels were 2540.65 (2215.4 - 2909.2) pg/ml and 1110.45 (885.45 - 1527.65) pg/ml, respectively, with a p-value of less than 0.001. In the hemodialysis group, 25 patients (62.5%) had low bone mineral density (BMD) with a Z-score of under -2.0. Eighteen of these patients had low BMD in both the neck of the femur and lumbar spines. Additionally, there was a significant increase in serum DKK-1 level in patients with low BMD (2567.35 (2303.8 - 3108.1) pg/ml) compared to patients with normal BMD (2454 (1859 - 2820) pg/ml) (p = 0.041). There was also a significant positive correlation between DKK1 level and phosphorus, alkaline phosphatase, and Parathormone serum levels. In conclusion, the study indicates a clear correlation between DKK-1 and BMD in children undergoing maintenance hemodialysis. DKK1 is a promising biomarker for CKD-MBD.

关键词： DKK-1 Children Haemodialysis Bone Density Status

An Efficient Breast Cancer Detection Framework for Medical Diagnosis Applications

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Computers, Materials & Continua 2022年第1期70卷 1315-1334页

作者： naglaa F.Soliman naglaa S.Ali Mahmoud I.Aly Abeer D.Algarni Walid El-Shafai Fathi E.Abd El-Samie Department of Information Technology College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversityRiyadh84428Saudi Arabia Department of Electronics and Communications Faculty of EngineeringZagazig UniversityZagazig44519Egypt International Academy for Engineering and Media Science October CityEgypt Department of Electronics and Electrical Communications Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt

Breast cancer is themost common type of cancer,and it is the reason for cancer death toll in women in recent *** diagnosis is essential to handle breast cancer patients for treatment at the right *** with mammography is the preferred examination for breast cancer,as it is available worldwide and ***-Aided Detection(CAD)systems are used to analyze medical images to detect breast cancer,*** death rate of cancer patients has decreased by detecting tumors early and having appropriate treatment after *** of mammogram images has four main steps:pre-processing,segmentation of the region of interest,feature extraction and classification of the images into normal or abnormal *** paper presents an efficient framework for processing of mammogram images and introduces an algorithm for segmentation of the images to detect *** pre-processing step of mammogram images includes removal of digitization noise using a 2D median filter,removal of artifacts using morphological operations,and contrast enhancement using a fuzzy enhancement *** proposed fuzzy image enhancement technique is analyzed and compared with conventional techniques based on an Enhancement Measure(EME)and local contrast *** comparison shows an outstanding performance of the proposed technique from the visual and numerical *** segmentation process is performed using Otsu’smultiple thresholding *** method segments the image regions into five classes with variable intensities using four *** effectiveness is measured based on visual quality of the segmentation output,as it gives details about the image and positions of *** performance of the proposed framework is measured using Dice coefficient,Hausdorff,and Peak Signal-to-Noise Ratio(PSNR)*** segmented tumor region with the proposed segmentation method is 81%of the ground truth region provided by an ***,the proposed framew

关键词： Breast cancer mammogram images CAD contrast enhancement fuzzy logic segmentation

Text-Independent Algorithm for Source Printer Identification Based on Ensemble Learning

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Computers, Materials & Continua 2022年第10期73卷 1417-1436页

作者： naglaa F.El Abady Mohamed Taha Hala H.Zayed Department of Computer Science Faculty of Computers and Artificial IntelligenceBenha University13518Egypt School of Information Technology and Computer Science(ITCS) Nile University12677Egypt

Because of the widespread availability of low-cost printers and scanners,document forgery has become extremely *** or signatures are used to protect important papers such as certificates,passports,and identification *** the origins of printed documents is helpful for criminal investigations and also for authenticating digital versions of a document in today’s *** printer identification(SPI)has become increasingly popular for identifying frauds in printed *** paper provides a proposed algorithm for identifying the source printer and categorizing the questioned document into one of the printer classes.A dataset of 1200 papers from 20 distinct(13)laser and(7)inkjet printers achieved significant identification results.A proposed algorithm based on global features such as the Histogram of Oriented Gradient(HOG)and local features such as Local Binary Pattern(LBP)descriptors has been proposed for printer *** classification,Decision Trees(DT),k-Nearest Neighbors(k-NN),Random Forests,Aggregate bootstrapping(bagging),Adaptive-boosting(boosting),Support Vector Machine(SVM),and mixtures of these classifiers have been *** proposed algorithm can accurately classify the questioned documents into their appropriate printer *** adaptive boosting classifier attained a 96%*** proposed algorithm is compared to four recently published algorithms that used the same dataset and gives better classification accuracy.

关键词： Document forensics source printer identification(SPI) HOG LBP principal component analysis(PCA) bagging AdaBoost

Drone-based AI/IoT Framework for Monitoring,Tracking and Fighting Pandemics

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Computers, Materials & Continua 2022年第6期71卷 4677-4699页

作者： Abdelhamied A.Ateya Abeer D.Algarni Andrey Koucheryavy naglaa.F.Soliman Department of Information Technology College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversityRiyadh84428Saudi Arabia Department of Electronics and Communications Engineering Zagazig UniversityZagazigSharqia44519Egypt Department of Telecommunication Networks and Data Transmission the Bonch-Bruevich Saint-Petersburg State University of TelecommunicationsSaint Petersburg193232Russia

Since World Health Organization(WHO)has declared the Coronavirus disease(COVID-19)a global pandemic,the world has *** life’s fields and daily habits have moved to adapt to this new *** to WHO,the probability of such virus pandemics in the future is high,and recommends preparing for worse *** this end,this work provides a framework for monitoring,tracking,and fighting COVID-19 and future *** proposed framework deploys unmanned aerial vehicles(UAVs),e.g.;quadcopter and drone,integrated with artificial intelligence(AI)and Internet of Things(IoT)to monitor and fight *** consists of two main systems;AI/IoT for COVID-19 monitoring and drone-based IoT system for *** two systems are integrated with the IoT paradigm and the developed algorithms are implemented on distributed fog units connected to the IoT network and controlled by software-defined networking(SDN).The proposed work is built based on a thermal camera mounted in a face-shield,or on a helmet that can be used by people during *** detected images,thermal images,are processed by the developed AI algorithm that is built based on the convolutional neural network(CNN).The drone system can be called,by the IoT system connected to the helmet,once infected cases are *** drone is used for sterilizing the area that contains multiple infected *** proposed framework employs a single centralized SDN controller to control the network *** developed system is experimentally evaluated,and the results are *** indicate that the developed framework provides a novel,efficient scheme for monitoring and fighting COVID-19 and other future pandemics.

关键词： Internet of Things convolutional neural network fog computing software-defined networking COVID-19 drone

Dynamic S-Box Generation Using Novel Chaotic Map with Nonlinearity Tweaking

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Computers, Materials & Continua 2023年第5期75卷 3011-3026页

作者： Amjad Hussain Zahid Muhammad Junaid Arshad Musheer Ahmad naglaa F.Soliman Walid El-Shafai School of Systems and Technology University of Management and TechnologyLahore54700Pakistan Department of Computer Science University of Engineering and TechnologyLahore54700Pakistan Department of Computer Engineering Jamia Millia IslamiaNew Delhi110025India Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Security Engineering Lab Computer Science DepartmentPrince Sultan UniversityRiyadh11586Saudi Arabia Department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt

A substitution box(S-Box)is a crucial component of contemporary cryptosystems that provide data protection in block *** the moment,chaotic maps are being created and extensively used to generate these SBoxes as a chaotic map assists in providing disorder and resistance to combat cryptanalytical *** this paper,the construction of a dynamic S-Box using a cipher key is proposed using a novel chaotic map and an innovative tweaking *** projected chaotic map and the proposed tweak approach are presented for the first time and the use of parameters in their workingmakes both of these dynamic in *** tweak approach employs cubic polynomials while permuting the values of an initial S-Box to enhance its cryptographic *** of the parameters are provided using the cipher key and a small variation in values of these parameters results in a completely different unique *** analysis and exploration confirmed that the projected chaoticmap exhibits a significant amount of chaotic *** security assessment in terms of bijectivity,nonlinearity,bits independence,strict avalanche,linear approximation probability,and differential probability criteria are utilized to critically investigate the effectiveness of the proposed S-Box against several *** proposed S-Box’s cryptographic performance is comparable to those of recently projected S-Boxes for its adaption in real-world security *** comparative scrutiny pacifies the genuine potential of the proposed S-Box in terms of its applicability for data security.

关键词： Substitution-box chaotic map data security tweaking