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Plasma Fatty Acid Composition in Men over 50 in the USA and Japan

Food and nutrition Sciences 2018年第6期9卷 703-710页

作者： A. Takada F. Shimizu Y. Ishii M. Ogawa T. Takao S. Koba M. R. Carnethon W. S. harris International Projects on Food and Health (nPO) Tokyo Japan Faculty of Human Life and Environmental Sciences Showa Women’s University Tokyo Japan Division of Cardiology Department of Medicine Showa University School of Medicine Tokyo Japan Department of Preventive Medicine Feinberg School of Medicine of Northwestern University Chicago Illinois Department of Medicine University of South Dakota School of Medicine and Omegaquant LLC Sioux Falls USA

Background: Coronary heart disease (CHD) rates differ markedly between the US and Japan. Fatty acid profiles have been linked to risk for CHD. Few studies have compared the plasma fatty acid composition, including trans fatty acids, in Japanese and US subjects. Methods: Fasting blood samples were taken from healthy older (>age 50) American (n = 76) and Japanese (n = 44) men, and plasma levels of 23 fatty acids were analyzed by gas chromatography and expressed as a percent of total fatty acids. Results: As expected, plasma levels of long-chain ω3 fatty acids (docosahexaenoic and eicosapentaenoic acids, DHA and EPA) were higher in Japanese men and ω6 fatty acids (e.g., arachidonic acid, AA) were lower compared with American men. Plasma levels of the major industrially-produced trans fatty acids (IP-TFAs;elaidic and linoelaidic acids) were far higher in American men, and levels of the potentially cardioprotective, primarily ruminant-derived trans fatty acid palmitoelaidic acid (POA) were higher in Japanese. Plasma levels of saturated or monounsaturated fatty acids were also higher in the American men. Conclusion: There are multiple differences in plasma fatty acid profiles between American and Japanese older men. The higher levels of DHA and EPA, along with the lower levels of the IP-TFAs, are consistent with the markedly lower risk for coronary heart disease in Japan vs. the US.

关键词： Plasma Fatty Acid Composition

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双源CT成像用于经导管主动脉瓣置换术前计划:诊断阻塞性冠状动脉疾病的准确性

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国际医学放射学杂志 2015年第3期 277-278页

作者： B.S.harris C.n.De Cecco U.J.Schoepf D.H.Steinberg R.R.Bayer A.W.Krazinski 楼清清 Heart and Vascular Center Medical University of South CarolinaAshley River TowerMSC 226 25 Courtenay Dr Charleston SC 29425

目的评估用于经导管主动脉瓣置换(TAVR)术前计划的CT检查对诊断阻塞性冠状动脉疾病(CAD)的准确性。材料与方法经机构伦理委员会批准,免签知情同意书,

关键词：阻塞性冠状动脉疾病双源 CT

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Prevalence of refractive errors in children of Puerto Rico

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International Journal of Ophthalmology(English edition) 2023年第3期16卷 434-441页

作者： Héctor C.Santiago Mayra Rullán Katerin Ortiz Andrés Rivera Mónica nieves JoséPiña Zulmaris Torres Yvette Mercado Inter American University of Puerto Rico School of Optometry500 John Will HarrisBayamónPuerto Rico 00957USA

AIM:To determine the prevalence of refractive error in 5-to 17-year-old schoolchildren in Puerto ***:A quantitative descriptive study of 2867 children aged 5 to 17y from all seven educational regions of Puerto Rico was conducted from 2016–*** error was determined via static and subjective *** with distance acuity≤20/40 or near visual acuity≤20/32 had a cycloplegic *** analysis included descriptive statistics,correlation coefficient,Kruskal-Wallis,Chi-square,and t test ***:Twenty percent of the children had a spherical equivalent refractive error≤-0.50 D,3.2%had a spherical equivalent≥+2.00 D,and 10.4%had astigmatism≥1 *** was a statistically(but non-clinically)significant myopic change in spherical equivalent refractive error with age(Pnce of myopia increased with age(Pnot hyperopia(P=0.59)or astigmatism(P=0.51).Males had a significantly higher hyperopic spherical equivalent than females(Pnce of myopia(Pn males,but there was no difference in the hyperopia(P=0.74)or astigmatism prevalence(P=0.87).COnCLUSIOn:The prevalence of a spherical equivalent equal to or less than-0.50 D(myopia,20.7%)is one of the highest among similar-aged children *** studies should explore the rate of myopia progression in children in Puerto *** children must be monitored to examine the need for treatment of myopia progression.

关键词： children refractive error Puerto Rico myopia hyperopia

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高危肥厚型心肌病患者中埋藏式除颤器放电的决定因素

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世界核心医学期刊文摘（心脏病学分册） 2007年第12期3卷 43-44页

作者： Woo A. Monakier D. harris L. 徐永城 Division of Cardiology Toronto General Hospital 4N- 506 200 Elizabeth Street Toronto Ont. M5G 2C4 Canada.Dr

目的:确定肥厚型心肌病(HCM)患者中埋藏式心脏复律除颤器(ICD)适当与不适当放电的决定因素。设计:回顾性队列研究。地点:一所教学医院的ICD门诊。患者:61例出于心脏性猝死(SCD)一级或二级预防目的而植入ICD的HCM患者。观察指标:①适当... 详细信息

目的:确定肥厚型心肌病(HCM)患者中埋藏式心脏复律除颤器(ICD)适当与不适当放电的决定因素。设计:回顾性队列研究。地点:一所教学医院的ICD门诊。患者:61例出于心脏性猝死(SCD)一级或二级预防目的而植入ICD的HCM患者。观察指标:①适当和不适当ICD放电的分析;②ICD放电的预测因素。结果:ICD植入时的年龄(x±s)为46±18岁(极差10～79)。

关键词：肥厚型心肌病 ICD 预测因素患者决定因素

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两万年来的中国多年冻土形成演化

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中国科学：地球科学 2019年第8期49卷 1197-1212页

作者：金会军金晓颖何瑞霞罗栋梁常晓丽王绍令 Sergey S MARCHEnKO 杨思忠易朝路李世杰 Stuart A harris 中国科学院寒区旱区环境与工程研究所冻土工程国家重点实验室兰州730000 哈尔滨工业大学土木工程学院哈尔滨150090 中国科学院大学资源与环境学院北京100049 湖南科技大学建筑与城乡规划学院湘潭411201 Permafrost Laboratory Geophysical Institute University of Alaska Fairbanks Fairbanks 99775 USA GFZ German Research Centre for Geosciences Telegrafenberg Potsdam D-14473 Germany 中国科学院青藏高原研究所青藏高原环境变化与地表过程重点实验室北京100010 中国科学院地球化学研究所贵阳550081 Department of Geography University of Calgary Calgary Alberta T2N 1N4 Canada

利用大量的古多年冻土遗迹和古冰缘现象,并佐以古冰川、孢粉及动物化石等资料,重建了20ka以来中国多年冻土演化进程.结果表明,在末次冰期最盛期(LGM,或末次多年冻土最大期LPMax),中国多年冻土面积达到了5.3×10^6~5.4×10^6km^2(现今中... 详细信息

利用大量的古多年冻土遗迹和古冰缘现象,并佐以古冰川、孢粉及动物化石等资料,重建了20ka以来中国多年冻土演化进程.结果表明,在末次冰期最盛期(LGM,或末次多年冻土最大期LPMax),中国多年冻土面积达到了5.3×10^6~5.4×10^6km^2(现今中国多年冻土面积的3倍多),而全新世大暖期(HMP,或末次多年冻土最小期LPMin),中国多年冻土面积曾缩减至0.80×10^6~0.85×10^6km^2(约为现今中国多年冻土面积的50%).按照古冻土遗迹的年代及分布等特征,在确定LGM和HMP两个主要时段的冻土格局基础上,将20ka以来中国多年冻土演化进程划分为7个阶段:晚更新世LGM(20000~10800aBP)多年冻土强烈扩展,达到LPMax;早全新世气候剧变期(10800至8500~7000aBP)多年冻土较稳定但相对缩减阶段;中全新世HMP(8500~7000至4000~3000aBP)多年冻土强烈退化阶段,多年冻土缩减到LPMin;晚全新世新冰期(4000~3000至1000aBP)冻土扩展阶段;晚全新世中世纪暖期(1000~500aBP)多年冻土相对退化阶段;晚全新世小冰期(LIA, 500~100aBP)冻土相对扩展阶段,以及近代升温期(近百年来)多年冻土持续退化阶段.本文重建了各时段内古气候、古地理环境以及多年冻土分布范围和其他特征.

关键词：冻土演化冷生楔形构造末次冰期最盛期(LGM) 全新世大暖期(HMP) 中国

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Ractopamine Hydrochloride and Estradiol + Trenbolone Acetate Implants Alter Myogenic mRnA, <i>β</i>-Adrenergic Receptors, and Blood Metabolites

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Open Journal of Animal Sciences 2020年第3期10卷 447-467页

作者： T. L. harris Z. K. Smith F. R. B. Ribeiro M. A. Jennings G. J. Vogel B. J. Johnson Department of Animal and Food Sciences Texas Tech University Lubbock Texas USA Elanco Animal Health Greenfield Indiana USA Department of Animal Science South Dakota State University Brookings South Dakota USA Phytobiotics north America LLC Cary North Carolina USA Elanco Animal Health Greenfield Indiana USA

Two commonly used growth promotants in the United States beef industry are β-agonists and anabolic steroid hormones. Each has been shown to increase lean muscle deposition in cattle provided treatments of each growth technology, but much is still unknown of how steroidal implants and β-agonists work in combination. It was our goal to determine the effect of implant strategy and β-agonist administration in beef feedlot heifers (n = 264). A 3 × 2 factorial randomized complete block design was used with 2 levels of OPT and 3 different durations of terminal implant (TI) windows for a total of 6 treatment groups with 9 replications. Terminal implants (20 mg estradiol/200 mg trenbolone acetate implant, Component TE-200) were provided to heifers 140 d from slaughter (TI140), 100 d from slaughter (TI100), or 60 d from slaughter (TI60). Animals receiving the later two TI being first implanted on day 0 (8 mg estradiol/80 mg trenbolone acetate implant, Component TE-IH). The second treatment of the cattle received was the orally active beta adrenergic agonist, ractopamine-hydrochloride (RH) in the form of Optaflexx®(OPT;0 (nO) or 200 (YES) mg/hd·d-1) over the final 28 days of the trial. Thirty animals were subjected to longissimus muscle (LM) biopsies on d 0, 40, 80, 112, and at slaughter on d 140 to view mRnA levels of myogenic related genes and protein quantities of the β1-adrenergic receptor (β1 AR) and β2-adrenergic receptor (β2 AR). On the same days, blood samples were taken from 108 animals to assess changes in plasma blood urea nitrogen (BUn), non-esterified fatty acids (nEFA) and progesterone due to treatments. Relative mRnA levels of myosin heavy chain IIX (MHC IIX), AMPKα, and IGF-I wer

关键词： β-Agonist β-Receptor Muscle Hypertrophy Myogenic mRnA Ractopamine Hydrochloride Steroid Hormones

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多胎妊娠中产科子宫切除术是否更常见

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世界核心医学期刊文摘（妇产科学分册） 2005年第9期1卷 59-60页

作者： Francois K. Ortiz J. harris C. 高雪莲 17918 north 80th Place Scottsdale AZ 85255 United States Dr.

OBJECTIVE: To compare the occurrence of peripartum hysterectomy between sing le ton and multiple gestations. METHODS: This was a historical cohort study compari ng the occurrence of peripartum hysterectomy between singleton and multiple gest a tions at Banner Good Samaritan Regional Medical Center, Phoenix, Arizona, from J anuary 1, 1996, to December 31, 2001. RESULTS: During the study years, 42,595 si ngleton, 1,131 twin, 164 triplet, 35 quadruplet, and 2 quintuplet deliveries occ urred. A total of 100 peripartum hysterectomies were performed. Of these hystere ctomies, 88 occurred in singletons, 5 in twins, 6 in triplets, and 1 in quadrupl ets. The overall occurrence of peripartum hysterectomy was 2.28 per 1000, and th e occurrence of emergent peripartum hysterectomy was 1.73 per 1000. Multiple ges tations had a significantly greater risk of emergent peripartum hysterectomy tha n singletons (odds ratio [OR] 6.04, 95%confidence interval [CI] 3.28-11.11; P nce was more pronounced among higher-order multiple gestat ions: twins (OR 2.95, 95%CI 1.22-7.13, P = .03), triplets (OR 25.22, 95%CI 11 .02-57.77, P nd quadruplets (OR 19.53, 95%CI 3.34-114.69, P = .04). When compared with singletons, higher-order multiple gestations had nearly a 2 4-fold increased risk of emergent peripartum hysterectomy (OR 23.97, 95%CI 11. 05-51.99, P nCLUSIOn: Multiple gestations have a significantly highe r occurrence of emergent peripartum hysterectomy than singletons. This informati on should be used in counseling and managing patients with these pregnancies.

关键词：子宫切除术多胎妊娠分娩情况胞胎队列研究亚利桑那州孕妇孕期尼克斯日至

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影响奶牛着色性状两重要QTL的互作关系分析

影响奶牛着色性状两重要QTL的互作关系分析

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中国畜牧兽医学会第七届养牛学分会2009年学术研讨会

作者：刘林 B.harris 王雅春孙东晓俞英张毅张沅中国农业大学动物科技学院北京奶牛中心 Livestock improvement Corporation Priv.Bag 3016Hamilton.N.Z.

＜正＞引言本研究即基于由BoviQuest项目所建立的荷斯坦-娟姗牛F2杂交群体,依据项目前期针对着色性状进行的全基因组扫描结果,对定位到其中两个重要QTL的作用关系进行了分析,以期对试验动物着色特征的形成进行合理推论,并为对应QTL区段... 详细信息

＜正＞引言本研究即基于由BoviQuest项目所建立的荷斯坦-娟姗牛F2杂交群体,依据项目前期针对着色性状进行的全基因组扫描结果,对定位到其中两个重要QTL的作用关系进行了分析,以期对试验动物着色特征的形成进行合理推论,并为对应QTL区段内候选基因的互作关系研究提供基础信息。

关键词： QTL 着色性状互作关系奶牛

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基于多标记信息最小二乘回归QTL定位方法的模拟研究

基于多标记信息最小二乘回归QTL定位方法的模拟研究

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第十五次全国动物遗传育种学术讨论会

作者：刘林 B. harris 王雅春孙东晓俞英张毅张沅中国农业大学动物科技学院北京奶牛中心 Livestock improvement Corporation Priv. Bag 3016Hamilton. N.Z.

＜正＞引言基于利用多标记信息最小二乘回归的QTL定位方法,具有速度快、操作简单等特点,被广泛的应用于动物QTL定位研究。

关键词： QTL 多标记信息最小二乘回归 F2群体半同胞群体

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葡糖胺、硫酸软骨素及二者联合使用治疗痛性膝关节炎

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世界核心医学期刊文摘(神经病学分册) 2006年第8期 1-2页

作者： Clegg D.O. Reda D.J. harris C.L. 郭俊 University of Utah Division of Rheumatology 4B200 School of Medicine 50 N. Medical Dr. Salt Lake City UT 84132 United States Dr.

Background: Glucosamine and chondroitin sulfate are used to treat osteoarthritis. The multicenter, double- blind, placebo- and celecoxib- controlled Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) evaluated their efficacy and safety as a treatment for knee pain from osteoarthritis. Methods: We randomly assigned 1583 patients with symptomatic knee osteoarthritis to receive 1500 mg of glucosamine daily, 1200 mg of chondroitin sulfate daily, both glucosamine and chondroitin sulfate, 200 mg of celecoxib daily, or placebo for 24 weeks. Up to 4000 mg of acetaminophen daily was allowed as rescue analgesia. Assignment was stratified according to the severity of knee pain (mild [n = 1229] vs. moderate to severe [n = 354]). The primary outcome measure was a 20 percent decrease in knee pain from baseline to week 24. Results: The mean age of the patients was 59 years, and 64 percent were women. Overall, glucosamine and chondroitin sulfate were not significantly better than placebo in reducing knee pain by 20 percent. As compared with the rate of response to placebo (60.1 percent), the rate of response to glucosamine was 3.9 percentage points higher (P = 0.30), the rate of response to chondroitin sulfate was 5.3 percentage points higher (P = 0.17), and the rate of response to combined treatment was 6.5 percentage points higher (P = 0.09). The rate of response in the celecoxib control group was 10.0 percentage points higher than that in the placebo control group (P = 0.008). For patients with moderate- to- severe pain at baseline, the rate of response was significantly higher with combined therapy than with placebo (79.2 percent vs. 54.3 percent, P = 0.002). Adverse events were mild, infrequent, and evenly distributed among the groups. Conclusions: Glucosamine and chondroitin sulfate alone or in combination did not reduce pain effectively in the overall group of patients with osteoarthritis of the knee. Exploratory analyses suggest that the combination of glucosamine

关键词：葡糖胺安慰剂空白剂膝关节炎硫酸软骨素

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