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Evaluation of groundwater quality using pollution index of groundwater(PIG) and non-carcinogenic health risk assessment in part of the Gangetic basin

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Acta Geochimica 2021年第3期40卷 419-440页

作者： Apoorv Verma n.b.singh Environmental Science and Engineering Civil Engineering DepartmentInstitute of Engineering and TechnologyDr.A.P.J.Abdul Kalam Technical UniversityLucknow 226021India Harcourt butler Technical University Kanpur 208002India

The aim of this study was to evaluate groundwater fitness for domestic and irrigational use in Unnao district of Uttar Pradesh,*** this study,block wise(n=16)groundwater samples were collected,and measured parameters were analyzed using the pollution index of groundwater(PIG),various irrigational indices,and graphical *** results of this study suggested that most of the parameters were within the prescribed limits of WHO and bIS,excluding F-(0.4 to 2.6 mg L^(-1))and Fe^(2+)(0.1 to 1.7 mg L^(-1)).Concentrations of total dissolved solids(TDS)were exceeded the desirable limit(>500 mg L^(-1))in 43.75%of samples at some *** Gibbs plot revealed that groundwater chemistry was governed by rock-water interaction in the region,especially silicate *** Piper plot suggested that Ca^(2+)-HCO3-is dominant hydrochemical facies in the area followed by mixed Ca^(2+)-na^(+)-HCO_(3)^(-)type,na^(+)-Cl^(-)type,and na^(+)-HCO_(3)^(-)*** evaluation revealed that the contribution of F-and Fe2+in groundwater degradation is high in comparison to other elements in the region,about 18.75%samples showed low pollution,while about 6.25%samples shows moderate pollution,and 6.25%samples reflected high *** human health risk(HHR)assessment finding suggested that children(mean:1.36)are more vulnerable than adults(mean:1.01).Sodium absorption ration(SAR),Residual sodium carbonate(RSC),and Permeability index(PI)indicated that most of the groundwater was suitable for irrigation,whereas,Magnesium hazard ration(MHR)and Potential salinity(PS)indices suggested that only 37.5%and 56.25%of the samples were suitable for irrigational use,*** regional study would help in decision making for stakeholders and relevant authorities in the execution of groundwater management and remediation plans in the area.

关键词： Groundwater Pollution index of groundwater Irrigational indices Silicate weathering Human health risk

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Coal fy ash:an emerging material for water remediation

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International Journal of Coal Science & Technology 2022年第3期9卷 18-49页

作者： n.b.singh Anupam Agarwal Anindita De Pragya singh Department of Chemistry and biochemistry Sharda UniversityGreater NoidaIndia

Coal fy ash(CFA)is a byproduct of thermal power plant and collected from fue gases by *** of CFA depends on the type of coal used and it has both crystalline and amorphous *** is considered to be an environmental pollutant and used in number of *** is a useful material and widely used in cement production and as a promising adsorbent for water *** used for remediation of wastewater solves problems related to water quality issues and waste *** physical properties such as porosity,surface area,morphology,and chemical composition(iron oxide,alumina,silica,titania,etc.)make CFA efcient material for wastewater *** is also converted to geopolymer,which is used as an adsorbent and ***,organic compounds,toxic heavy metal ions,*** been removed using CFA and modifed CFA *** adsorption efciencies have been reported for diferent adsorbate and CFA *** of adsorption isotherm and kinetic models have been discussed.

关键词： Coal fy ash Adsorbent Dye Geopolymer Water remediation Pollutants

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Characterization of bi2/3Cu3Ti4O12 ceramics synthesized by semi-wet route

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Progress in natural Science:Materials International 2016年第6期26卷 567-571页

作者： Pooja Gautam Ankur Khare Sunita Sharma n.b.singh K.D.Mandal Department of Chemistry Indian Institute of Technology(BHU) Department of Chemistry & biochemistry University of Maryland

bi2/3Cu3Ti4O12（bCTO） ceramic was synthesized by the semi-wet route using metal nitrate solutions and solid TiO2powder in a stoichiometric ratio. Fourier transform infrared（FTIR） study of bCTO precursor powder and calcined ceramic showed the presence of alcoholic functional groups and the stretching band of Ti-O and Cu-O respectively. X-ray diffraction（XRD）, scanning electron microscope（SEM） and energy dispersive x-ray spectroscopy（EDX） were employed to characterize the structure, surface morphology and purity of the sintered bCTO ceramic respectively. X-ray diffraction study confirmed the single phase formation of bCTO ceramic at1073 K. The average dimension of grains calculated by SEM and AFM was found to be in the range of 0.73 ±0.2 μm with clear grain boundaries. Magnetic property was investigated over a wide temperature range 2–300 K at a magnetic field of 7 tesla. The Curie temperature was calculated by zero field cooled(MZFC) and field cooled(MFC) magnetization at 100 Oe applied field which was found to be 125 K. The sintered bCTO ceramic shows high dielectric constant（ε'=2.9×10～4） at 323 K and 100 Hz.

关键词： Ceramic Synthesis Structural properties Magnetic properties

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用汽相生长氯化亚汞晶体制作的器件

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压电与声光 1988年第1期 64-66+63页

作者： n.b.singh 杨清宗美·西屋研究开发中心

本文叙述了用氯化亚汞晶体制作的光信号处理和声光可调器件的初步试验结果。实验测得的激光波长为0.633、3.39和10.6μm的声光可调滤光器的调谐曲线与理论曲线完全一致。

关键词：晶体光信号换能器传感器测深仪汽相生长晶体生长氯化亚汞氯化物器件

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掺有氟硅酸钠矿化剂的熟料在立窑的煅烧过程研究

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国外建材科技 1994年第1期15卷 19-22页

作者： n.b.singh 何其捷印度

由于燃料变差和水泥成本提高,矿化剂正在印度立窑小水泥厂生产熟料中起着十分重要的作用。一个日产50吨熟料的小型立窑水泥厂采用了掺入氟硅酸钠矿化剂的工艺。该厂采用两种质量的煤,一种是优质焦炭煤粉,其粉煤炭为24％～26％,发热量为5... 详细信息

由于燃料变差和水泥成本提高,矿化剂正在印度立窑小水泥厂生产熟料中起着十分重要的作用。一个日产50吨熟料的小型立窑水泥厂采用了掺入氟硅酸钠矿化剂的工艺。该厂采用两种质量的煤,一种是优质焦炭煤粉,其粉煤炭为24％～26％,发热量为5300kcals/kg,另一种是低放热量劣质煤屑,粉煤灰为35％,发热量为4200kcals/kg。采用的原料是含2％氧化镁的易烧石灰石。试验结果表明,原料中添加0.3％的氟硅酸钠(按重量计),效果最佳,并且熟料质量明显改进,这有利于抗压强度提高和体积安定性(蒸压法)的改善。矿化剂明显减少扬尘,有利于料球的机械强度,也使熟料结块硬度低,易磨性好。生料中的MgO含量略高有利于氟化为在阿利特内混合,并提高其活性。实际上,阿利特含量较高,C_2S和C_3S含量较低。含有氟硅酸钠的立窑熟料也可用于制作含有高炉粒状炉渣和粉煤灰的混合水泥。试验结果表明,当混合材掺量为60％时,28天龄期的抗压强度比不掺的高。

关键词：竖炉煅烧氟硅酸钠矿化剂熟料

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Exploring the role of n-acetyltransferases in diseases:a focus on n-acetyltransferase 9 in neurodegeneration

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neural Regeneration Research 2025年第10期20卷 2862-2871页

作者： Prajakta Deshpande Anuradha Venkatakrishnan Chimata Amit singh Department of biology University of DaytonDaytonOHUSA Premedical Program University of DaytonDaytonOHUSA Center for Tissue Regeneration and Engineering at Dayton(TREnD) University of DaytonDaytonOHUSA Integrative Science and Engineering Center University of DaytonDaytonOHUSA Center for Genomic Advocacy(TCGA) Indiana State UniversityTerre HauteINUSA

Acetyltransferases,required to transfer an acetyl group on protein are highly conserved proteins that play a crucial role in development and *** acetylation is a common post-translational modification pivotal to basic cellular *** to 80%-90%of proteins are acetylated during translation,which is an irreversible process that affects protein structure,function,life,and *** this review,we have discussed the various n-acetyltransferases present in humans,their function,and how they might play a role in ***,we have focused on n-acetyltransferase 9 and its role in microtubule *** have shed light on how n-acetyltransferase 9 and acetylation of proteins can potentially play a role in neurodegenerative *** have specifically discussed the n-acetyltransferase 9-acetylation independent function and regulation of c-Jun n-terminal kinase signaling and microtubule stability during development and neurodegeneration.

关键词： acetyl-coenzyme A Alzheimer’s disease animal models cell death drosophila eye human disease c-Jun n-terminal kinase signaling n-Acetyltransferases n-acetyltransferase 9 neurodegeneration

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A Comprehensive Survey on Federated Learning Applications in Computational Mental Healthcare

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 49-90页

作者： Vajratiya Vajrobol Geetika Jain Saxena Amit Pundir Sanjeev singh Akshat Gaurav Savi bansal Razaz Waheeb Attar Mosiur Rahman brij b.Gupta Institute of Informatics and Communication University of DelhiDelhi110021India Maharaja Agrasen College University of DelhiDelhi110096India Computer Engineering Ronin InstituteMontclairNJ 07043USA Department of Research and Innovation Insights2TechinfoJaipur302001India University Centre for Research and Development(UCRD) Chandigarh UniversityChandigarh140413India Management Department College of Business AdministrationPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia CCRI&Department of Computer Science and Information Engineering Asia UniversityTaichung413Taiwan Symbiosis Centre for Information Technology(SCIT) Symbiosis International UniversityPune411057India Center for Interdisciplinary Research University of Petroleum and Energy Studies(UPES)Dehradun248007India

Mental health is a significant issue worldwide,and the utilization of technology to assist mental health has seen a growing *** aims to alleviate the workload on healthcare professionals and aid *** applications have been developed to support the challenges in intelligent healthcare ***,because mental health data is sensitive,privacy concerns have *** learning has gotten some *** research reviews the studies on federated learning and mental health related to solving the issue of intelligent healthcare *** explores various dimensions of federated learning in mental health,such as datasets(their types and sources),applications categorized based on mental health symptoms,federated mental health frameworks,federated machine learning,federated deep learning,and the benefits of federated learning in mental health *** research conducts surveys to evaluate the current state of mental health applications,mainly focusing on the role of Federated Learning(FL)and related privacy and data security *** survey provides valuable insights into how these applications are emerging and evolving,specifically emphasizing FL’s impact.

关键词： Depression emotional recognition intelligent healthcare systems mental health federated learning stress detection sleep behaviour

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nano-Enhanced Dairy Scum biodiesel blends:Unleashing the Power of Aluminium Oxide for Sustainable and Efficient Engine Performance

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Journal of Thermal Science 2025年第1期34卷 283-302页

作者： Veeranna MODI Prasad b.RAMPURE Sunil Kumar SHETTY Madeva nAGARAL Channa Keshava nAIK n Johar MGM Muhammad Irsyad AbDULLAH Abdullah I.AL-MAnSOUR Shamshad ALAM KLE College of Engineering and Technology ChikodiVisvesvaraya Technological University nitte (Deemed to be University) NMAM Institute of Technology (NMAMIT)Department of Mechanical Engineering Aircraft Research and Design Centre HAL Department of Mechanical Engineering BGS College of Engineering and TechnologyBengaluruAffiliated to Visvesvaraya Technological University Management and Science University Department of Civil Engineering College of EngineeringKing Saud University

This study investigates the effect of aluminium oxide nanoparticlesaddition to biodiesel blends made from dairy milk scum on performance and combustion characteristics of the diesel *** dispersion of Al2O3nanoparticles in b20 blends at different concentrations was done with the help of *** number of blends were prepared for the *** Machine learning algorithms(Random Forest（RF）and Catboost) was used for the *** results show that in comparison to biodiesel blends without nanoparticles,the kinematic viscosity and density is higher for fuel blends with *** these Fuel blends have higher calorific *** blends exhibited reduced brake Specific Fuel Consumption（bSFC） of2.85% than the blends without nano particles(Dairy Scum Methyl Ester biodiesel 20%+neat Diesel 80%（in volume）,DSMEb20),57.14% less CO,40.8% less hydrocarbon,and increased nOxemissions compared to conventional diesel,contributing to the development of environmentally friendly and renewable biofuel blends with *** b20nP30 is the optimal blend for performance and emission *** study concludes with findings on enhanced brake Thermal Efficiency（bTE） of 26.29% in 3×10-5（in volume） Al2O3nanoparticle-blended DSME b20 and other DSME b20 fuel blends,emphasizing the importance of optimal nanoparticle *** correlation matrix shows how engine load,efficiency measures（bTE,bSFC）,and emissions（CO,CO2,nOx,Smoke） are connected in complex *** results help us understand the complicated dynamics of engine performance and emission characteristics ***'s diagram for bTE and bSFC shows that Catboost-based bTE models perform superior to RF-based models during the training as well as testing *** results were obtained for CO and CO2emission results.

关键词： Al2O3 concentration CI engine Dairy Scum Methyl Ester biodiesel

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Impacts of PI3K/protein kinase b pathway activation in reactive astrocytes: from detrimental effects to protective functions

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neural Regeneration Research 2025年第4期20卷 1031-1041页

作者： Ramón Pérez-núñez María Fernanda González Ana María Avalos Lisette Leyton Cellular Communication Laboratory Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile Advanced Center for Chronic Diseases(ACCDiS) Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile Instituto de Ciencias biomédicas Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

Astrocytes are the most abundant type of glial cell in the central nervous *** injury and inflammation,astrocytes become reactive and undergo morphological and functional *** on their phenotypic classification as A1 or A2,reactive astrocytes contribute to both neurotoxic and neuroprotective responses,***,this binary classification does not fully capture the diversity of astrocyte responses observed across different diseases and *** analysis has revealed that reactive astrocytes have a complex landscape of gene expression profiles,which emphasizes the heterogeneous nature of their *** actively participate in regulating central nervous system inflammation by interacting with microglia and other cell types,releasing cytokines,and influencing the immune *** phosphoinositide 3-kinase(PI3K)/protein kinase b(AKT)signaling pathway is a central player in astrocyte reactivity and impacts various aspects of astrocyte behavior,as evidenced by in silico,in vitro,and in vivo *** astrocytes,inflammatory cues trigger a cascade of molecular events,where nuclear factor-κb serves as a central mediator of the pro-inflammatory ***,we review the heterogeneity of reactive astrocytes and the molecular mechanisms underlying their *** highlight the involvement of various signaling pathways that regulate astrocyte reactivity,including the PI3K/AKT/mammalian target of rapamycin(mTOR),αvβ3 integrin/PI3K/AKT/connexin 43,and notch/PI3K/AKT *** targeting the inactivation of the PI3K/AKT cellular signaling pathway to control reactive astrocytes and prevent central nervous system damage,evidence suggests that activating this pathway could also yield beneficial *** dual function of the PI3K/AKT pathway underscores its complexity in astrocyte reactivity and brain function *** review emphasizes the importance of employing astrocyte-exclusive models to underst

关键词： inflammation integrins neuroprotective neurotoxic phosphatidylinositol 3-kinase reactive astrocytes signal transduction Thy-1(CD90)

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Amyloid-beta pathology-induced nanoscale synaptic disruption:the case of the GAbA_b-GIRK assembly

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neural Regeneration Research 2025年第5期20卷 1409-1410页

作者： Rafael Lujan Alejandro Martín-belmonte Sergi Ferré Francisco Ciruela Synaptic Structure Laboratory Instituto de Biomedicina de la UCLM(IB-UCLM)Departamento de Ciencias MédicasInstituto de Investigación en Salud de Castilla-La Mancha(IDISCAM)Facultad de MedicinaUniversidad Castilla-La ManchaCampus BiosanitarioC/AlmansaAlbaceteSpain Integrative neurobiology Section National Institute on Drug AbuseIntramural Research ProgramNational Institutes of HealthBaltimoreMDUSA Pharmacology Unit Department of Pathology and Experimental TherapeuticsSchool of Medicine and Health SciencesInstitute of NeurosciencesUniversity of BarcelonaNeuropharmacology&Pain GroupNeuroscience ProgramBellvitge Institute for Biomedical ResearchL’Hospitalet de LlobregatSpain

Alzheimer's disease (AD) is characterized by an imbalance between excitatory and inhibitory brain networks,leading to aberrant homeostatic synaptic *** has progressively been recognized as syna ptopathy and syna ptic dysfunction has been identified as a key component of its pathogenesis (Schirinzi et al.,2020).Syna ptic dysfunction is believed to precede synapse loss,a primary biological correlate of cognitive decline in AD,inevita bly associated with neuronal death.

关键词： Alzheimer pathology

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