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n.w developmen.s.in.high-pres.ure X-ray diffraction.beamlin. for diamon. an.il cell at s.rin.-8

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Matter an. Radiation.at Extremes 2020年第1期5卷 49-58页

作者： n.Hirao s.I.Kawaguchi K.Hiros. K.s.imizu E.Ohtan. Y.Ohis.i Japan.s.n.hrotron.Radiation.Res.arch In.titute SayoHyogo 679-5198Japan Departmen. of Earth an. Plan.tary s.ien.e The University of TokyoTokyo 113-0033Japan Earth-Life s.ien.e In.titute Tokyo Institute of TechnologyTokyo 152-8550Japan Cen.er of s.ien.e an. Techn.logy Un.er Extremes.Con.ition. Graduate School of Engineering ScienceOsaka UniversityOsaka 560-8531Japan Departmen. of Earth s.ien.e Graduate School of ScienceTohoku UniversitySendai 980-8578Japan

An.overview of the recen.ly ren.vated high-pres.ure X-ray diffraction.XRD)BL10XU beamlin. for the diamon. an.il cell at s.rin.-8 is.*** ren.vation.in.ludes.the replacemen. of the X-ray s.urce an. mon.chromator,en.an.ed focus.n. s.s.ems.for high-en.rgy XRD,an. recen. progres. in.the s.mple en.iron.en. con.rol techn.ques.that are available for high-pres.ure *** s.multan.ous.meas.remen. techn.ques.for combin.tion.with XRD,s.ch as.Raman.s.atterin. s.ectros.opy an. Mos.bauer s.ectros.opy,have been.developed to obtain.complemen.ary in.ormation.un.er extreme *** advan.ed techn.ques.are expected to make s.gn.fican. con.ribution. to in.depth un.ers.an.in. of various.an. complicated high-pres.ure *** experien.e gain.d with the BL10XU beamlin. could help promote high-pres.ure res.arch in.future s.n.hrotron.radiation.facilities.

关键词： beam gain.d extreme

s.atial dis.ribution.of in.ecticide res.s.an. Check update population. of Aedes.aegypti an. Ae. albopictus.an. firs. detection.of V410L mutation.in.Ae. aegypti from Cameroon

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In.ectious.Dis.as.s.of Poverty 2022年第4期11卷 96-97页

作者： Matthew Mon.gomery James.F.Harwood Aurelie P.Yougan. Theodel A.Wils.n.Bahun.Armel n.Tedjou Chris.ophe Ros.an. Keumen. Aus.on.Marm Kilpatrick Charles.s.Won.j Bas.le Kamgan. Cen.re for Res.arch in.In.ectious.Dis.as.s P.O.Box 13591YaoundeCameroon 不详

Backgroun.:Den.ue(DEn.),chikun.un.a(CHIKV)an. Zika virus.ZIKV),are mos.uito-born. virus.s.of medical importan.e in.mos. tropical an. s.btropical *** con.rol,primarily through in.ecticides.remain. the primary method to preven. their ***,we evaluated in.ecticide res.s.an.e profles.an. iden.ifed importan. un.erlyin. res.s.an.e mechan.s.s.in.population. of Aedes.aegypti an. *** from s.x differen. region. in.Cameroon.to pes.icides.common.y us.d durin. military an. civilian.public health vector con.rol ***:Aedes.mos.uitoes.were s.mpled as.larvae or pupae between.Augus. 2020 an. July 2021 in.s.x location. acros. Cameroon.an. reared un.il the n.xt gen.ration.*** an. *** adults.from G1 were tes.ed followin. World Health Organ.zation.WHO)recommen.ation. an. *** GO adults.s.reen.d with real time meltin. curve qPCR an.lys.s.to gen.type the F1534C,V1016l an. V410L Aedes.kdr *** butoxide(PBO)as.ays.an. real time qPCR were carried out from s.me cytochrome p450 gen.s.kn.wn.to be in.olved in.metabolic *** an.lys.s.were performed us.n. Chi-s.uare tes. an. gen.ralized lin.ar ***:Los. of s.s.eptibility was.obs.rved to all in.ecticides.*** rates.from tes.s.with 0.25%permethrin.varied from 24.27%to 85.89%in.*** an. from 17.35%to 68.08%in.*** rates.for 0.03%deltamethrin.were between.23.30%an. 88.20%in.*** an. between.69.47%an. 84.11%in.*** foun. a moderate level of res.s.an.e again.t ben.iocarb,with mortality rates.ran.in. from 69.31%to 90.26%in.*** an. from 86.75%to 98.95%in.*** PBO pre-expos.re,we foun. partial or fully res.ored s.s.epti bility to pyrethroids.an. *** gen.s.Cyp9M6F88/87 an. Cyp9J10 were overexpres.ed in.*** population. from Douala s.tes.res.s.an. to permethrin.an. ***6P12 was.highly expres.ed in.alphacypermethrin.an. permethrin.res.s.an. A

关键词： Arbovirus Aedes.aegypti Aedes.albopictus In.ecticide res.s.an.e Kn.ck down.res.s.an.e Cytochrome P450 mon.oxygen.s.s Cameroon

In.egration.of Image Proces.in. an. Databas. Man.gemen. s.s.ems

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Integration of Image Processing and Database Management Syst...

Evaluation.of an.in.eractive virtual s.rgical rotation.durin. the COVID-19 pan.emic

ICIG’2000 Firs. In.ern.tion.l Con.eren.e on.Image an. Graphics.-Image an. Graphic Techn.logy Toward 21s. Cen.ury an. Beyon.

作者： n.s.MERZLYAKOV V.n.KARn.UKHOV L.I.RUBAn.V In.titute for In.ormation.Tran.mis.ion.Problems Russian Academy of Sciences 19 Bolshoi Karetny per. Moscow 101447 GSP4 Russia In.titute for In.ormation.Tran.mis.ion.Problems Russian Academy of Sciences 19 Bolshoi Karetny per. Moscow 101447 GSP4 Russia In.titute for In.ormation.Tran.mis.ion.Problems Russian Academy of Sciences 19 Bolshoi Karetny per. Moscow 101447 GSP4 Russia

＜正＞ This.article s.mmarizes.the res.lts.of our res.arch aimed to the developmen. of methods. algorithms. an. s.ftware for image acquis.tion. digital proces.in., an. creation.of textual-graphical databas.s.of archival photo-documen.s.an. an.in.egrated s.s.em for proces.in. an. archivin. of photo-documen.s. The developed methods. algorithms. an. s.ftware tools.were s.cces.fully tes.ed un.er creation.of textual-graphical databas.s. Thes. databas.s.have s.arted the con.ers.on.proces. of un.que collection. accumulated an. s.ored at the differen. organ.zation. of the Rus.ian.Academy of s.ien.es.in.o the digital form.

关键词： Digital Image Proces.in. Textual-Graphical Databas. Relation.l Databas.

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World Journ.l of Otorhin.laryn.ology-Head an. n.ck s.rgery 2022年第4期8卷 302-307页

作者： Yas.een.M.Byrn.s.n.il n.Luu Ariel s.Fros. Tiffan. n.Chao Robert M.Brody s.even.B.Can.ady Karthik Rajas.karan.Rabie M.s.an.i Jas.n.G.n.wman Perelman.s.hool of Medicin. at the Un.vers.ty of Pen.s.lvan.a Jordan Medical Education Center3400 Civic Center BlvdPhiladelphia19104PAUSA Departmen. of Otorhin.laryn.ology-Head& Neck SurgeryHospital of the University of Pennsylvania3400 Spruce StreetPhiladelphia19104PAUSA

Objective:To evaluate medical s.uden. an. atten.in. s.rgeon.experien.es.with a n.vel in.eractive virtual Otolaryn.ology-Head an. n.ck s.rgery(OHn.)medical s.uden. elective durin. the COVID-19 *** Des.gn.A virtual OHn. elective was.created,with three compon.n.s.(1)in.eractive virtual operatin. room(OR)experien.e us.n. live-s.ream video-con.eren.in.,(2)telehealth clin.c,(3)virtual ***:OHn. Departmen. at the Un.vers.ty of Pen.s.lvan.a(May 2020 to Jun. 2020).Methods.s.x medical s.uden.s.from the Un.vers.ty of Pen.s.lvan.a;five atten.in. *** s.rveys.were des.gn.d an. dis.ributed to participatin. medical s.uden.s.an. atten.in. *** in.luded 5-poin. Likert s.ale items.with 1 in.icatin."n.t at all"an. 5 in.icatin."very much s.".Res.lts.Res.on.e rate was.100%for both *** on.average rated the education.l value of the telehealth experien.e as.4.2±1.2,an. the virtual OR experien.e as.4.0±*** s.uden.s.n.5,83%)in.icated that they had en.ugh expos.re to faculty they met on.this.rotation.to as. for a letter of recommen.ation.LOR)for res.den.y if n.eded,while atten.in. s.rgeon. had an.average res.on.e of 3.0±1.0 when.as.ed how comfortable they would feel writin. a LOR for a s.uden. they met through the rotation.A majority of s.uden.s.n.4,67%)felt they con.ected en.ugh with faculty durin. the rotation.to as. for *** the s.uden.s.n.5,50%)in.icated that the rotation.allowed them to evaluate the departmen.'s.culture either"extremely well"or"s.mewhat well".Con.lus.on.:Overall,participatin. s.uden.s.des.ribed this.in.ovative virtual s.rgical rotation.as.an.education.lly an. profes.ion.lly valuable *** the con.in.ed s.s.en.ion.of vis.tin. s.uden. rotation. due to the COVID-19 pan.emic,this.virtual model may have con.in.ed relevan.e to medical education.

关键词： Virtual s.rgical education Otolaryn.ology Un.ergraduate medical education Covid-19 Telemedicin. s.rgical video capture

胸腔镜下修复新生儿先天性膈疝:成功治疗的入选标准

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世界核心医学期刊文摘（儿科学分册） 2006年第2期2卷 42-43页

作者： All men.in.er n. John.on.s.M. 王经纬 Departmen. of Pediatric s.rgery Vanderbitt Children's Hospital Nashville TN 37232 -9780 United States

Backgroun./Purpos.: Complication. of open.con.ers.on. hypercarbia, an. in.es.in.l in.ury have plaguedmin.mally in.as.ve approaches.to con.en.tal diaphragmatic hern.a (CDH) repair in.n.on.tes. To s.fely begin.us.n. min.mally in.as.ve techn.ques.for n.on.tal CDH repair, we formulated preoperative s.lection.criteria an. operative techn.ques.that would en.an.e chan.es.for s.cces.ful thoracos.opic primary diaphragm repair an. un.omplicated outcome. Methods. Durin. the period from Jan.ary 2003 to October 2004, n.on.tes.were s.lected for thoracos.opic CDH repair us.n. an.tomic an. phys.ologic criteria. An.tomically, all patien.s.were required to have s.omach in.the abdomen.by radiography. Phys.ologically, all patien.s.were required to be on.min.mal ven.ilator s.pport with preoperative ven.ilator peak in.piratory pres.ures.in.the low 20 mm Hg. n. patien. could have clin.cal eviden.e of pulmon.ry hyperten.ion.at the time of s.rgery. Thoracos.opic CDH repair was.performed us.n. 3 trocars.(3 an. 5 mm). The hern.a con.en.s.were reduced in.o the abdomen.us.n. 5-mm Hg in.ufflation. an. the diaphragms.were repaired primarily us.n. in.errupted 3-0 Ethibon. s.mple s.tures.(Ethicon. In., Pis.ataway, n.). Pos.erolateral diaphragm s.itches.were pas.ed aroun. the pos.erolateral ribs.an. tied extracorporeally. Res.lts. Thirty n.on.tes.with CDH were admitted to Children. s.Hos.ital Bos.on.an. Van.erbilt Children. s.Hos.ital durin. the s.udy period. Eight patien.s.(27% ) met s.lection.criteria an. 7 un.erwen. thoracos.opic CDH repair. Primary diaphragmatic repair was.s.cces.fully accomplis.ed thoracos.opically in.all n.on.tes.without perioperative complication. Preoperative an.tomic criteria correlated accurately with in.act es.phageal hiatus.an. primary diaphragm repair. Phys.ologically, each patien. tolerated in.rathoracic in.ufflation.an. CDH repair without clin.cal pulmon.ry hyperten.ion.or blood pres.ure lability. Three patien.s.had in.raoperative res.iratory acidos.s.that was.revers.

关键词：生理学标准先天性膈疝胸腔镜下修复术新生儿术前患者术后并发症治疗腹腔镜下儿童医院

Pan.reatic en.ymes.an. abdomin.l adipos. tis.ue dis.ribution.in.n.w-on.et prediabetes.diabetes.after acute pan.reatitis

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World Journ.l of Gas.roen.erology 2021年第23期27卷 3357-3371页

作者： Juyeon.Ko Loren.s.udder-Hill Jaelim Cho s.kin. H Bharmal Maxim s.Petrov s.hool of Medicin. University of AucklandAuckland 1142New Zealand

BACKGROUn. n.w-on.et prediabetes.diabetes.after acute pan.reatitis.n.DAP)is.the mos. common.s.quela of pan.reatitis.an. it differs.from type 2 prediabetes.diabetes.mellitus.T2DM).AIM To s.udy the as.ociation. between.circulatin. levels.of pan.reatic amylas.,pan.reatic lipas.,chymotryps.n.an. fat phen.types.in.n.DAP,T2DM,an. *** In.ividuals.with n.DAP(n.30),T2DM(n.30),an. s.x-matched healthy in.ividuals.n.30)were *** fat phen.types.in.ra-pan.reatic fat,liver fat,s.eletal mus.le fat,vis.eral fat,an. s.bcutan.ous.fat)were determin.d us.n. the s.me magn.tic res.n.n.e imagin. protocol an. s.an.er magn.t s.ren.th for all ***-way an.lys.s.of covarian.e,lin.ar regres.ion.an.lys.s.an. relative importan.e an.lys.s.were *** In.ra-pan.reatic fat depos.tion.IPFD)was.higher in.n.DAP(9.4%±1.8%)an. T2DM(9.8%±1.1%)compared with healthy con.rols.7.8%±1.9%)after adjus.in. for covariates.P=0.003).s.milar fin.in.s.were obs.rved in.regards.to vis.eral fat volume(P=0.005),but n.t s.bcutan.ous.fat volume,liver fat,or s.eletal mus.le *** IPFD(β=-2.201,P=0.023)an. vis.eral fat volume(β=-0.004,P=0.028)were s.gn.fican.ly as.ociated with circulatin. levels.of pan.reatic amylas. in.n.DAP,but n.t in.T2DM or healthy *** the five fat phen.types.IPFD explain.d the highes. amoun. of varian.e in.pan.reatic amylas. con.en.ration.R2=15.3%out of 41.2%).n.n. of the phen.types.con.ributed mean.n.fully to the varian.e in.pan.reatic lipas. or *** Both n.DAP an. T2DM are characterized by in.reas.d IPFD an. vis.eral fat ***,on.y n.DAP is.characterized by s.gn.fican. in.ers. as.ociation. between.the two fat phen.types.an. pan.reatic amylas..

关键词： Amylas. Lipas. Chymotryps.n Pan.reatitis Diabetes In.ra-pan.reatic fat Vis.eral fat Liver fat

Global ITs.divers.ty in.the s.orothrix s.hen.kii complex

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Fun.al Divers.ty 2014年第3期66卷 153-165页

作者： Xun.Zhou An.ers.n.M.Rodrigues.Peiyin. Fen. G.s.de Hoog Departmen. of Dermatology Affiliated Hospital of Chongqing Medical UniversityChongqingChina Cen.raalbureau voor s.himmelcultures.Kn.W Fun.al Biodivers.ty Cen.re PO Box 851673508 AD UtrechtThe Netherlands Departmen. of Microbiology Immunology and Parasitology-DMIPCellular Biology DivisionFederal University of São Paulo-UNIFESPSão PauloBrazil Third Affiliated Hos.ital Sun Yat-sen UniversityGuangzhouChina s.n.Yat-s.n.Memorial Hos.ital Sun Yat-Sen UniversityGuangzhouChina In.titute for Biodivers.ty an. Ecos.s.em Dyn.mics University of AmsterdamAmsterdamThe Netherlands Pekin. Un.vers.ty Health s.ien.e Cen.er Research Center for Medical MycologyBeijingChina

Molecular phylogen. has.revealed that s.orotrichos.s.is.caus.d by s.veral s.orothrix s.ecies.which differ in.clin.cal *** complex is.embedded within.Ophios.oma,a gen.s.main.y compris.n. fun.i that live in.as.ociation.with bark beetles.but differs.by a high virulen.e towards.human. an. other *** differen. ecology is.corroborated by phylogen.tic *** aim of the pres.n. s.udy was.to determin. the validity of the rDn. in.ern.l tran.cribed s.acer(ITs.region.as.a marker for diagn.s.ics.of s.ecies.in.the clin.cal group,us.n. betatubulin.s.quen.es.to calibrate s.ecies.*** topology of the two gen. trees.was.con.ordan.,an. all clin.cally relevan. s.orothrix s.ecies.could eas.ly be recogn.zed by mean. of the ITs.*** in.reas.d geographic s.mplin. did n.t affected delimitation.s.cces. in.the clin.cal clade of the *** complex.

关键词： s.orothrix s.hen.kii s.orotrichos.s Taxon.my Phylogen. ITs Barcodin.

CLn.3编码蛋白Batten.n.n.端是与蛋白结合的功能域(英文)

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北京大学学报（医学版） 2006年第1期38卷 38-40页

作者： Dorota n. MOROZIEWICZ Wein. JU Rocks.en. ZHOn. n.n.ert ZHOn. Departmen. of Human.Gen.tics New York State Institute for Basic Research in Developmental Disabilities Staten Island NY 10314 USA s.mmer s.uden. Harvard College Cambridge MA Deptartmen. n.n.ology SUNY Heahh Science Center Brooklyn NY 北京大学医学遗传中心、北京大学基础医学院医学遗传学系北京100083

Objective: Batten.dis.as. （BD）, the juven.le form of n.uron.l ceroid lipofus.in.s.s.（n.Ls., is.pathological characterized by fin.in. lys.s.mal s.orage of autofluores.en. lipofus.in. with un.que ultras.ructural profiles. The gen. un.erlyin. BD is.des.gn.ted CLn. an. en.odes.a protein. Batten.n. of un.n.wn.fun.tion.that localizes.in.lys.s.mes.an./or mitochon.ria. Previous.y, we hypothes.zed that Batten.n.as.ociates.with other membran. protein.s. to form a membran. complex. Dys.un.tion.of this.complex could res.lt in.the pathological chan.es.of BD, an. pos.ibly in.other n.Ls. Two s.ch membran.us.protein., the s.ow an. fas. Batten.n.in.eractive protein. （BIPs.an. BIPf） of un.n.wn.fun.tion., have been.iden.ified. In.this.s.udy, we have characterized the fun.tion.l domain. of Batten.n.that in.eract with both BIP protein.. Methods. Protein.protein.in.eraction. with a yeas. two-hybrid s.s.em were employed. A “deletion.as.ay” was.employed to localize the in.eractive s.gmen.（s.. Differen. len.ths.of cDn. s.quen.es.lackin. exon.1-5 were us.d to expres. CLn.-en.oded protein. lackin. n.termin.l s.gmen.s.in.the yeas. two-hybrid s.s.em. n.termin.l exon. of CLn. were deleted with PCR-clon.n. ***: We elimin.ted the pos.ibility of in.eractin. domain. from the exon.7-en.oded region.becaus. both Batten.n.an. mBatten.n.in.eract with the BIP protein.. We have s.own.that peptide s.quen.es.en.oded by exon. 2 an. 4 of CLn. gen. in.lude the fun.tion.l domain. by which Batten.n.in.eracts.with the BIP protein.. Con.lus.on. Our s.udies.provide eviden.e that the n.termin.s.of Batten.n.is.the fun.tion.l domain.for thes. protein.in.eraction..

关键词：神经元蜡样质脂褐质沉积病基因 CLn. 蛋白质相互作用 n.端

Partial Differen.ial Equation. that are Hard to Clas.ify

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Journ.l of Partial Differen.ial Equation. 2012年第1期25卷 41-65页

作者： HOWIs.n.s. D. LACEY A. A. OCKEn.On.J. R. OCIAM Mathematical Institute University of Oxford 24-29 St. Giles＇ Oxford OX1 3LB UK. Maxwell In.titute for Mathematical s.ien.es and School of Mathematical and Computer Sciences Heriot-Watt University Riccarton Edinburgh EH14 4AS UK.

s.mi-lin.ar n.x n.s.s.ems.of the form Aδu/δ＋Bδ/δy=f can.gen.rally be s.lved, at leas. locally, provided data are impos.d on.n.n.characteris.ic curves. There are at mos. n.characteris.ic curves.an. they are determin.d by the coefficien. matrices.on.the left-han. s.des.of the equation.. We con.ider cas.s.where s.ch problems.become degen.rate as.a res.lt of ambiguity as.ociated with the defin.tion.of characteris.ic curves. In.s.ch cas.s. the exis.en.e of s.lution. requires.res.riction. on.the data an. s.lution. might n.t be un.que.

关键词： Lin.ar s.s.ems.of firs.-order PDEs clas.ification can.n.cal s.s.ems.