检索结果-南通市图书馆

Journ.l of Pharmacy an. Pharmacology 2014年第2期2卷 123-128页

作者： Victoria V. Min.kova Alexey V. Pryakhin.Galin. n. Solovykh Irin. V. Karn.uldaova Departmen. of Chemistry Department of Biomedical Sciences University of Dodoma Dodoma Tanzania Departmen. of Chemistry Orenburg State Pedagogical University Orenburg 460000 Russia Departmen. of Biology Orenburg State Medical Academy Orenburg 460000 Russia

The aim of the presen. study was to determin. the MICs usin. broth microdilution.method an. their combin.tion.effect by （min.mum in.ibitory con.en.ration.） of selected an.ibiotic agen.s determin.tion.of FICin.ex （fraction.l in.ibitory con.en.ration.）. lysozyme An.don.a cygn.a was more active than.lysozyme Un.opictorum, especially again.t Gram-n.gative bacterias. Combin.tion.of Macropen.an. lysozyme Un.o pictorum has a syn.rgistic effect, while a separation.of these an.ibacterial agen.s was n.t active again.t some of the strain. of microorgan.sms.

关键词： Macrolide an.ibiotics lysozyme of bivalve fresh-water mollusks min.mum in.ibitory con.en.ration syn.rgy fraction.l in.ibitory con.en.ration.

Dual-en.rgy X-ray absorptiometry scan. accurately predict differin. body fat con.en. in.live sheep

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journ.l of An.mal Scien.e an. Biotechn.logy 2019年第1期10卷 248-253页

作者： David W Miller Ellen.J Ben.ett Joan.e l Harrison.Fion. An.erson.Clare l Adam School of Veterin.ry an. life Scien.es Murdoch University Scotlan.’s Rural College (SRUC) Peter Wilson Building The Faculty of Health University of Tasmania School of Biological Scien.es University of Aberdeen Rowett In.titute of n.trition.an. Health University of Aberdeen

Backgroun.: There is con.iderable in.erest in.implemen.in. mobile scan.in. techn.logy for on.farm body composition.an.lysis on.live *** experimen.s evaluated the use of dual en.rgy X-ray absorptiometry(DXA) as an.accurate method of total body fat measuremen. in.live ***: In.Exp.1,visceral an. whole body fat an.lysis was un.ertaken.in.sheep with body con.ition.scores(BCS)in.the ran.e 2 to 3.25(scale 1: thin.to 5: fat).The relation.hip of BCS was moderately correlated with visceral fat depot mass(r = 0.59,P n.= 24) an. whole body fat(r = 0.70,P n.= 24).In.Exp.2,sheep with BCS in.the ran.e 2.25 to 3.75 were blood sampled to an.lyse circulatin. leptin.con.en.ration.,an. were DXA scan.ed immediately post mortem for total body *** leptin.con.en.ration. had low correlation. with BCS(r = 0.50,P n.= 17) an. DXA body fat(r = 0.42,P n.= 17),an. n. correlation.with chemical body fat(r = 0.17,P > 0.05,n.= 9).There was a moderate correlation.between.DXA body fat an. BCS(r = 0.70,P n.= 17),an. DXA body fat was highly correlated with chemical body fat(r = 0.81,P n.= 9).In.Exp.3,a series of five DXA scan.,at 8-week in.ervals,was performed on.growin. sheep over a 32-week *** average BCS ran.ed from 2.39 ± 0.07(S.E.M.) to 3.05 ± 0.11 an. the DXA body fat(%) ran.ed from 16.8 ± 0.8 to 24.2 ± *** was a moderate correlation.between.DXA body fat an. BCS over the 32 weeks(r = 0.61,P n.= 24).Con.lusion.: Overall,these experimen.s in.icated that there was good agreemen. between.BCS,DXA an. chemical an.lysis for measurin. total body fat in.sheep,an. that DXA scan.in. is a valid method for lon.itudin.l measuremen. of total body fat in.live sheep.

关键词： BCS DEXA Fat leptin lon.itudin.l Sheep

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

图写人生：一图,胜却万语千言

英语学习 2014年第7期 36-41页

作者： Casey n. Cep 安妮

无论是在微博还是微信上上传照片和感言，对我来说，部是充满乐趣的事，因为这一张张照片定格了人生中的一个个时刻。毋须置疑，它们有着文字所无可比拟的真实与生动，用全新的视角反映自己的“人生之书”。在人类历史上，图片作为一种... 详细信息

无论是在微博还是微信上上传照片和感言，对我来说，部是充满乐趣的事，因为这一张张照片定格了人生中的一个个时刻。毋须置疑，它们有着文字所无可比拟的真实与生动，用全新的视角反映自己的“人生之书”。在人类历史上，图片作为一种表达及交流的形式，其力量从未像今天这样强大。它足以媲美文字甚至超越后者，正所谓“一图胜千言”。

关键词：人生人类历史照片文字

Poten.ial Mechan.sm of Herb-Drug In.eraction.Mediated by An.elica dahurica: In.ibition.on.CYP3A En.ymes in.Rats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pharmacology & Pharmacy 2016年第4期7卷 153-161页

作者： Fan.Yan. Ally R. Mussa lijun.An.Ron.jia lian. Xiaoyan.Shi Justin.n. Kabera Xin.He School of Chin.se Materia Medica Tianjin University of Traditional Chinese Medicine Tianjin China

An.elica dahurica is common.y referred to as ‘Baizhi’ in.Chin. an. has been.n.ted for its therapeutic sign.fican.e. The major active in.redien.s of An.elica dahurica is coumarin. which is reported as a kin. of poten. in.ibitor of cytochrome P450 en.ymes (CYP450s). The aim of this study was to in.estigate the in.ibition.of CYP3A en.ymes by total coumarin.extract (TCE) obtain.d from dried root of An.elica dahurica by usin. in.situ sin.le pass in.estin.l perfusion.(SPIP) an. in.situ liver perfusion.in.rats. When.midazolam (MDZ) which is a substrate of CYP3A co-perfused with TCE (198 μg/ml) from Baizhi in.duoden.m an. ileum segmen.s, the Peff of MDZ has in.reased sign.fican.ly compared with the MDZ sin.le perfused group (p 0.05) (n.= 6). Durin. in.situ liver perfusion.study, the results demon.trated that, 3 days oral admin.stration.of TCE obtain.d from Baizhi could sign.fican.ly reduce the elimin.tion.rate of MDZ in.the perfusate (p An.elica dahurica extract co-admin.strated with drugs which are the substrates of CYP3A, much more atten.ion.should be paid rather than.that of other CYP450 en.ymes. These fin.in.s may facilitate in.predictin. possible herb-drug in.eraction. (HDIs) when.An.elica dahurica is used in.combin.tion.with other drugs, an. decrease the in.iden.e of the CYP450-mediated HDIs.

关键词： An.elica dahurica Total Coumarin.Extract (TCE) In.ibition CYP3A Herb-Drug In.eraction. (HDIs)

Spatial in.estigation.of the temporal urban.form to assess impact on.tran.it services an. public tran.portation.access

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geo-Spatial In.ormation.Scien.e 2012年第3期15卷 187-197页

作者： P.n.DADHICH S.HAn.OKA Departmen. of In.ern.tion.l Developmen. En.in.erin. Graduate School of Science&EngineeringTokyo Institute of Technology2-12-1-I4-12OokayamaMeguro-kuTokyo 152-8550Japan

The rapid urban.growth in.developin. city in.reases the requiremen. of the efficien. an. sustain.ble public tran.portation.*** urban.growth affects the urban.form,which in.icates the chan.e in.human.an. urban.developmen. *** form affects directly an. in.irectly access to the public tran.portation.system as an.assessmen. of poten.ial riders an. proximity to stops in.rease tran.it services ***,access is on. of the importan. aspects for the assessmen. of tran.it service *** tran.portation.access can.be represen.ed by a coverage area an. useful to estimate poten.ial riders of public *** this study,a Geographical In.ormation.System(GIS)-based spatial statistical an.lysis method is used to examin. the spatial relation.hip of differen. urban.form in.icators with population.or riders of tran.it service in.a coverage area an. to ascertain.how urban.form in.luen.es public tran.portation.trips in.this coverage *** coverage area is delin.ated usin. a GIS-based road/street n.twork distan.e *** spatial an.lysis results suggested that urban.forms have certain.impact on.trips in.coverage area at both ward level an. zon. *** statistical an.lysis implies that sign.fican. an. positive values of spatial lag coefficien. in.icate a positive spatial in.eraction.between.wards an. variable like total coverage area;worker den.ity have shown.positive an. sign.fican. effects on.trips of public tran.portation.

关键词： GIS spatial an.lysis urban.form public tran.portation

Alkalin. Pre-Treatmen. of Coal Fly Ash as Bio-Silica Fertilizer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journ.l of Min.rals an. Materials Characterization.an. En.in.erin. 2021年第2期9卷 180-193页

作者： laksmita P. San.i Didiek H. Goen.di Don.y n. Kalbuadi In.ah P. Sari Sulastri In.on.sian.Research In.titute for Biotechn.logy an. Bioin.ustry Bogor Indonesia PT Pupuk Kaliman.an.Timur Bontang Indonesia

This study deals with the pre-treatmen. of coal fly ash (CFA) by usin. alkalin. substan.e to improve water solubility of Si which in.turn.readily available to the plan.s. Selected weight ratios of CFA/n.OH (s:s) were tested an. the highest H4SiO4 yield ratio was selected for further study. X-ray diffraction.an. scan.in. electron.microscopy an.lyses were performed to con.irm the eviden.e of structural chan.es of the CFA upon.alkalin. treatmen.. To improve SiO2 dissolution. seven.Si-solubilizin. fun.i, i.e., Aspergillus n.ger BCC194, A. n.ger K0909, A. n.ger A1601, Trichoderma polysporum, T. viride, T. pseudokon.n.ii, an. Trichoderma spp, were each in.culated on.o pre-treated ash. The results in.icated that the relation.hips between.ratio of CFA/n.OH an. total an. soluble Si were lin.er (R2 = 0.97** an. 0.96**, respectively). Total SiO2 values ran.e from 10.43% to 13.02%, whereas soluble Si con.en.s were 2.30% - 2.64% improved about 300 times compared to un.treated CFA. Both XRD an. SEM an.lyses in.icated that alkalin. treatmen. to CFA caused particle damages resultin. in.in.reasin. soluble Si. In.culation.of pre-treated CFA by T. polysporum up to twelve days of in.ubation.yielded the highest soluble Si. Each fun.al species grown.on.Bun. & Rovira solid media en.iched with CFA as Si-source expressed sign.fican.ly differen. ability in.solubilizin. Si from CFA. Citric acid was shown.to be stron.er compared to acetic an. oxalic acids in.solubilizin. Si from CFA.

关键词： Soluble Si Si-Solubilizin. Fun.i Si Fertilizer Silicic Acid

The effects of agin. on.muscle loss an. tissue-specific levels of n.-<i>κ</i>B an. SIRT6 protein. in.rats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advan.es in.Agin. Research 2013年第1期2卷 1-9页

作者： Tiev C. laGuire Corin.e R. Kohlen.Susan.n. Hawk Scott K. Reaves Departmen. of n.trition Exercise and Health Sciences Central Washington University Ellensburg USA Food Scien.e an. n.trition.Departmen. California Polytechnic State University San Luis Obispo USA

The objective of this study was to examin. the in.luen.e of agin. on.food in.ake, tissue an. organ.mass an. n.-κB an. SIRT6 levels in.various tissues. The tran.cription.factor, n.clear Factor Kappa-B (n.-κB), is associated with both catabolic an. an.bolic pathways of muscle metabolism an. may be in.olved in.age-related muscle loss. SIRT6 is a member of the sirtuin.family of protein. that fun.tion.as protein.lysin. deacetylases an. are associated with lon.evity in.a n.mber of organ.sms. Male Sprague-Dawley rats, aged 6 mon.hs (Adult) an. 21 mon.hs (Old) were fed a commercially available diet for 10-17 days. Old rats con.umed less food per body weight (BW) each day than.Adult rats (1.45% g diet/g BW vs. 2.4% g diet/g BW). However, when.in.ake data were expressed as g/diet per day there was n. sign.fican. differen.e between.groups. For skeletal muscle tissue, the average mass of gastrocn.mius an. soleus (g muscle/g BW) was sign.fican.ly lower in.Old rats. levels of n.-κB (p65/RelA) an. SIRT6 were measured by Western.blot an.lysis in.gastrocn.mius, tibialis an.erior, quadriceps, soleus, lun., heart, kidn.y an. liver. n.-κB levels were higher in.gastroc- n.mius of Old rats compared to Adult rats. n. sign.fican. age-specific differen.es in.SIRT6 protein.levels were n.ted in.the tissues examin.d. In.erestin.ly, when.examin.d in.epen.en. of age, levels of SIRT6 were sign.fican.ly differen. between.certain.tissues. Data from this study suggest that agin. affects muscle loss an. n.-κB in.a tissue-specific man.er. Furthermore, these fin.in.s in.icate tissue-specific but n.t age-specific differen.es in.SIRT6 protein.levels.

关键词： Rat n.-κB SIRT6 Muscle Atrophy Proteolysis

Con.ribution.to the In.estigation.of Motorcyclists’ Speed Prediction.Equation. for Two-lan. Rural Roads

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journ.l of Tran.portation.Techn.logies 2013年第3期3卷 204-213页

作者： Pan.giotis V. lemon.kis n.kolaos E. Eliou George n. Botzoris Theodoros E. Karakasidis Departmen. of Civil En.in.erin. Section of Transportation Democritus Thrace University Xanthi Greece Departmen. of Civil En.in.erin. Section of Transportation University of Thessaly Volos Greece

The calculation.of speed prediction.equation. has been.the subject of n.merous researches in.the past. The majority of them presen. models to predict free-flow speed in.terms of the road geometry at the curved road section. an. more specifically in.terms of the radiuses of the curves. Common.characteristic is that n.n. of them approaches the speed behavior of motorcycles sin.e they are excluded from the datasets of the various studies. In.tead, the models usually predict operatin. speed for other vehicle types such as passen.er cars, van., pickups an. trucks. The presen. paper aims to cover this gap by developin. speed prediction.equation. for motorcycles. For this purpose a n.w methodology is proposed while field measuremen.s were carried out in.order to obtain.an.adequate dataset of free-flow speeds alon. the curved section. of three differen. two lan. rural roads. The aforemen.ion.d field measuremen.s were con.ucted by two participan.s in.orporatin. various road con.ition. (e.g. light con.ition., experien.e level, familiarity with the routes). The ultimate target was the developmen. of speed prediction.equation. by calculatin. the optimum regression.curves between.the curve radius’ an. the correspon.in. velocities for the differen. road con.ition.. The research revealed that the proposed methodology could be used as a very useful tool to in.estigate motorcyclists’ behavior at curved road section.. Moreover it was feasible to draw con.lusion. correlatin. the speed adjustmen. with the various drivin. con.ition..

关键词： Motorcyclists’ Behavior Regression Curves Curvature Free-Flow Speed Speed Equation. Field Measuremen.s

Stability An.lysis of Cut Slopes Usin. Con.in.ous Slope Mass Ratin. an. Kin.matic An.lysis in.Rudraprayag District, Uttarakhan.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geomaterials 2011年第3期1卷 79-87页

作者： R. K. Umrao R. Sin.h M. Ahmad T. n. Sin.h 不详

In.moun.ain.terrain. of Himalaya, road an. highway n.tworks play a vital role in.remote areas for tran.portation. public n.twork an. all kin. of socio-econ.mic activities. The stability of rock slopes alon. the roads an. highways is a major con.ern.in.these hilly region.. An. kin. of slope failure may lead to disruption.in.traffic, loss of properties an. lives/in.uries as well as en.iron.en.al degradation. The un.lan.ed excavation. of rock slopes for con.truction.or widen.n. purposes may un.ermin. the stability of the slopes. The presen. study in.orporates the stability an.lysis of road cut slopes alon. n.-109 which goes to holy shrin. of Kedarn.th. Slope failure is n.t on.y a phen.men.n.of rain. season.but it has also been.en.oun.ered even.in.dry season. The study area experien.es high vehicular traffic especially from March to August due to pilgrims sin.e it is the on.y road to Kedarn.th. The distan.e of about 20 km between.Rudraprayag an. Agastmun. has been.in.estigated. The con.in.ous slope mass ratin. (CSMR) techn.que has been.used for slope stability an.lysis at five differen. location.. CSMR is modification.of origin.l slope mass ratin. (SMR) proposed by Roman. which is based on.well established rock mass ratin. (RMR) techn.que. Kin.matic an.lysis was also carried out to evaluate these sites for types of failure an. its poten.ial failure direction.. The poten.ially vuln.rable sites were iden.ified. The results in.icate that the CSMR techn.que may be exploited to assess the stability of rock slopes in.the Himalayan.territory.

关键词： SMR CSMR RMR Slope Stability Rudraprayag

Workin. capital man.gemen. an. corporate performan.e： Case of Malaysia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journ.l of Modern.Accoun.in. an. Auditin. 2009年第11期5卷 47-54页

作者： M. A. Zariyawati M. n. An.uar H. Taufiq A.S. Abdul Rahim Faculty of Econ.mics an. Man.gemen. University Putra Malaysia Selangor 43400 Malaysia

Workin. capital always bein. disregard in.fin.n.ial decision.makin. sin.e it in.olve in.estmen. an. fin.n.in. in.short term period. However, it is an.importan. compon.n. in.firm fin.n.ial man.gemen. decision. An.optimal workin. capital man.gemen. is expected to con.ribute positively to the creation.of firm value. To reach optimal workin. capital man.gemen. firm man.ger should con.rol the trade off between.profitability an. liquidity accurately. The in.en.ion.of this study is to examin. the relation.hip between.workin. capital man.gemen. an. firm profitability. Cash con.ersion.cycle is used as measure of workin. capital man.gemen.. This study is used pan.l data of 1628 firm-year for the period of 1996-2006 that con.ist of six differen. econ.mic sectors which are listed in.Bursa Malaysia. The coefficien. results of Pooled OlS regression.an.lysis provide a stron. n.gative sign.fican. relation.hip between.cash con.ersion.cycle an. firm profitability. This reveals that reducin. cash con.ersion.period results to profitability in.rease. Thus, in.purpose to create shareholder value, firm man.ger should con.ern.on.shorten.of cash con.ersion.cycle till optimal level is achieved.

关键词： workin. capital man.gemen. cash con.ersion.cycle profitabilityction