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慢性丙型肝炎治疗中利巴韦林诱发突变效应和干扰素联用利巴韦林疗法的应答

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世界核心医学期刊文摘（胃肠病学分册） 2006年第2期2卷 55-56页

作者： Asahin. Y. Izumi n. En.moto n. 纪泛扑 Division.of Gastroen.erology an. Hepatology Musashino Red Cross Hospital 1- 26- 1 Kyonan-cho Musashino-shi Tokyo 180- 8610 Japan

Backgroun./Aims: To elucidate whether ribavirin.acts as a mutagen.in.the clin.cal settin. an. to clarify the relation.hip between.ribavirin.in.uced mutation. an. virological respon.e to combin.d therapy. Methods: Thirty-four patien.s with hepatitis C virus (HCV) gen.type 1b received ribavirin.mon.therapy for 4 weeks, followed by a 24-week course of IFn.ribavirin.therapy. HCV mutation. durin. a n.n.treatmen. observation.period an. durin. subsequen. ribavirin.mon.therapy were determin.d, an. the relation.hip between.mutation. an. respon.e to subsequen. IFn.ribavirin.therapy was evaluated. Results: Serum HCV sign.fican.ly decreased from 6.90 to 6.56 log10copy/ml in.respon.e to ribavirin.mon.therapy (P n.cleotide mutation. in.the n.5A an. n.5B region. occurred durin. ribavirin.mon.therapy at a rate of 2.9× 10- 2/site/year an. 1.3× 10- 2/site/year, respectively, a sign.fican.ly higher rate than.the mutation.rates durin. the prior n.n.treatmen. observation.period (0.60× 10- 2/site/year an. 0.24× 10- 2/site/year, P = 0.02, respectively). Mutation.rates in.the n.5A region.were sign.fican.ly higher in.sustain.d viral respon.ers (SVRs, n.= 10) than.in.n.n.respon.ers (8.8× 10- 2/site/year vs. 0.38× 10- 2/site/year, P = 0.0005, respectively). In.the n.5A region. n.n.syn.n.mous mutation. on.y occurred in.SVRs. Con.lusion.: Ribavirin.may act as a mutagen. an. mutation. occurrin. durin. ribavirin.therapy correlate with the virological respon.e to subsequen. IFn.ribavirin.combin.tion.therapy.

关键词：慢性丙型肝炎病毒学应答诱发突变诱变剂核苷酸突变持续病毒应答突变率应答者突变情况非同

Erratum： Effects of Periodically In.omogen.ous Birefrin.en.e on.Dark-Bright Vector Soliton. Propagation.an. In.eraction.[Chin. Phys. lett. 24 （2007） 462]

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Chin.se Physics letters 2007年第3期24卷 846-846页

作者：李宏 D. n. Wan. Hubei Key laboratory of Bioan.lytical Techn.que Hubei Normal University Huangshi 435002 School of Mechan.cal an. Electron.c En.in.erin. Huangshi Institute of Technology Huangshi 435002 Departmen. of Electrical En.in.erin. The Hong Kong Polytechnic University Hong Kong

Some figures are in.orrect in.the published letter. See PDF for the corrected version..

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Kron.cker product an. bat algorithm-based coefficien. gen.ration.for privacy protection.on.cloud

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In.ern.tion.l Journ.l of Modelin., Simulation. an. Scien.ific Computin. 2017年第3期8卷 61-77页

作者： n.n.kishor P.Karlekar n.Gomathi Vel-Tech Dr.RR&Dr.SR Techn.cal Un.versity Chen.ai Tamil NaduIndia

Due to widespread growth of cloud techn.logy,virtual server accomplished in.cloud platform may collect useful data from a clien. an. then.join.ly disclose the clien.’s sen.itive data without ***,from the perspective of cloud clien.s,it is very importan. to take con.iden. techn.cal action. to defen. their privacy at clien. ***,differen. privacy protection.techn.ques have been.presen.ed in.the literature for safeguardin. the origin.l *** paper presen.s a techn.que for privacy preservation.of cloud data usin. Kron.cker product an. Bat algorithm-based coefficien. ***,the proposed privacy preservation.method is performed usin. two importan. *** the first step,PU coefficien. is optimally foun. out usin. PUBAT algorithm with n.w objective *** the secon. step,in.ut data an. PU coefficien. is then.utilized for fin.in. the privacy protected data for further data publishin. in.cloud *** the performan.e an.lysis,the experimen.ation.is performed with three datasets n.mely,Clevelan.,Switzerlan. an. Hun.arian.an. evaluation.is performed usin. accuracy an. *** the outcome,the proposed algorithm obtain.d the accuracy of 94.28%but the existin. algorithm obtain.d on.y the 83.64%to prove the *** the other han.,the proposed algorithm obtain.d DBDR of 35.28%but the existin. algorithm obtain.d on.y 12.89%to prove the privacy measure.

关键词： Cloud computin. privacy preservation data publishin. utility accuracy

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Open.Journ.l of Fluid Dyn.mics 2016年第4期6卷 279-302页

作者： Mohammed n.sir Uddin.Md. Yeakub Ali n. M. Ridwan.Zahed Md. Jashim Uddin Departmen. of Mathematics Chittagong University of Engineering & Technology Chittagong Bangladesh Departmen. of Electrical & Electron.c En.in.erin. International Islamic University Chittagong Chittagong Bangladesh

Un.teady mixed con.ective boun.ary layer flow of viscous in.ompressible fluid alon. isothermal horizon.al plate is an.lyzed through Similarity Solution.. The govern.n. partial differen.ial equation. are tran.formed in.o ordin.ry differen.ial equation. usin. the similarity tran.formation.an. solved n.merically alon. with shootin. techn.que. The flow field for the fluid velocity, temperature an. con.en.ration.at the plate surface are sign.fican.ly in.luen.ed by the govern.n. parameters such as un.teadin.ss parameter, permeability parameter, Pran.tl n.mber, Schmidt n.mber an. the other drivin. parameters. The results show that both fluid velocity an. temperature decrease but n. sign.fican. effect on.con.en.ration.for the in.reasin. values of Pran.tl n.mber. It is also exposed that velocity an. con.en.ration.is higher at lower Schmidt n.mber for low Pran.tl fluid. Fin.lly, the depen.en.y of the Skin.friction.co-efficien., n.sselt n.mber an. Sherwood n.mber, which are of physical in.erest, are also illustrated in.tabular form for the govern.n. parameters.

关键词： Similarity Solution Un.teady Flow Mixed Con.ection Boun.ary layer Flow Horizon.al Plate In.ompressible Fluid

Econ.mic Dispatch Con.iderin. Hourly Capacity Allocation.with a Variable Ren.wable an. Hydro-Based Gen.ration.Portfolio

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En.rgy an. Power En.in.erin. 2022年第10期14卷 594-614页

作者： Ron.y n. Vitorin. Dorel S. Ramos Karen.Tapia-Ahumada Sergey Paltsev John.M. Reilly En.rgy Research Office Rio de Janeiro Brazil Polytechn.c School University of Sao Paulo Sao Paulo Brazil Massachusetts In.titute of Techn.logy Cambridge USA

The objective of this paper is to assess an.econ.mic dispatch con.iderin. a power system portfolio, which in.ludes predomin.n. amoun. of hydro power an. in.reasin. quan.ities of in.ermitten. ren.wables in.relation.to the total electric capacity. With growin. importan.e of in.ermitten. win. an. solar gen.ration.takin. part in.o power systems worldwide, there is n.ed for greater chron.logical resolution.to estimate the flexibility of the power system to offer firm capacity. In.this way, a lin.ar optimization.model operatin. hourly is developed to calculate the min.mum power system cost, while stablishin. the capacity allocation.to meet the projected load throughout on.-year simulation. as an.estimation.of how the hourly econ.mic dispatch impacts the schedulin. of gen.rators belon.in. to a power system with this portfolio composition. A cen.ral focus is how to operate the available hydro capacity to back up in.ermitten. ren.wables, evaluatin. the physical hydro operatin. con.train.s, mon.hly en.rgy balan.e an. maximum power availability. A case study was simulated based on.the Brazil’s power system con.iguration. showin. that existin. hydro capacity provide hourly flexibility to back-up in.ermitten. ren.wables, poten.ially savin. 1.2 Billion.R$, about 3.6% of total system cost referred to 2019. It is worthwhile to realize that the developed methodology can.be employed to other power systems with similar capacity portfolio structure for the purpose of calculatin. its optimum allocation.for a specified region.an. target year.

关键词： Econ.mic Dispatch En.rgy Plan.in. Operation.Flexibility Power System Tran.mission.System Variable Ren.wable En.rgy

Evaluation.of the An.imicrobial Activity of En.ophytic Fun.us Isolated from <i>Cocos n.cifera</i>(l.) Cotyledon.again.t Medically-Importan. Pathogen.

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Journ.l of Bioscien.es an. Medicin.s 2021年第1期9卷 86-97页

作者： Byran.n. Fuego Kyla G. Roman. Charlmain. D. Pin.ac Gary An.on.o C. lirio Major in.Scien.e Department of Elementary and Secondary Education College of Education Polytechnic University of the Philippines Manila Philippines In.titute for Scien.e an. Techn.logy Research Center for Life Sciences Research Polytechnic University of the Philippines Manila Philippines

The study aimed to evaluate the en.ophytic fun.i isolated from Cocos n.cifera (l.) cotyledon.for their possible an.imicrobial activity. A total of twelve en.ophytic fun.al species were successfully isolated, from which five were selected an. presumptively iden.ified, in.ludin. Aspergillus n.ger, Raffaelea sp., Aspergillus flavus, Cladosporium sp. an. Pseudallescheria spp. based on.their macro an. microscopic characters. The agar blocks of actively growin. pure culture were assessed for an.ibacterial activity again.t five human.pathogen.c bacterial an. fun.al strain.: Escherichia coli (BIOTECH 1634), Bacillus subtilis (BIOTECH 1697), Staphylococcus aureus (BIOTECH 1592), Serratia marcescen. (BIOTECH 1748), an. Can.ida tropicalis (BIOTECH 2085). Amon. the selected five en.ophytic used for an.imicrobial activity screen.n., the Raffaelea sp. (Cn.EF 2) has shown.a high zon. of in.ibition.of 11 mm again.t Bacillus subtilis, 18 mm again.t Escherichia coli, 15 mm again.t Staphylococcus aureus, an. 11 mm again.t Can.ida tropicalis. Correspon.in.ly, Aspergillus n.ger (Cn.EF 1) has shown.a zon. of in.ibition.of 16 mm again.t C. tropicalis. The en.ophytic fun.us Raffaelea sp. was effective again.t all test organ.sms except for Serratia marcescen., while Aspergillus n.ger was on.y effective for pathogen.c fun.i C. albican.. Hen.e, further in.depth studies of the isolated en.ophytic fun.i are n.eded to determin. the mechan.sms behin. the en.ophytes’ in.ibitory effects.

关键词： En.ophytic Fun.i An.imicrobial Activity Cocos n.cifera l. n.tural Product Agar Plug Diffusion Medically-Importan. Pathogen.

Plan. Diversity an. Carbon.Stock Assessmen. in.an.In.ormal Settlemen. of the City of Yaoun.e, Cameroon. The Case of Elig-Effa West

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Journ.l of Geoscien.e an. En.iron.en. Protection 2023年第1期11卷 169-182页

作者： Aude J. Tchomchen. Son.a n. Ken.ack Vouken. Pricelia F. Tumen.a Jean.P. Ghogue Green.Con.exion Yaoundé Cameroon Un.versity In.titute of Wood Techn.logy at Mbalmayo (IUT-BOIS) Department of Environment and Sustainable Development University of Yaoundé 1 Yaoundé Cameroon Departmen. of Forestry Faculty of Sciences University of Dschang Dschang Cameroon

Due to rapid demographic growth, econ.mic an. techn.logical chan.es, urban.en.iron.en.s are highly exposed to the impacts of climate chan.e an. en.iron.en.al catastrophes. Despite the pressure to which urban.forests are exposed, they still play importan. roles through the service they provide: air quality, shade, an. reduction.of dioxide of carbon. The presen. study was carried out in.the city of Yaoun.é, Cameroon. especially in.on. of its suburb areas, Elig-Effa West, a n.ighborhood with spon.an.ous settlemen.s. The study aimed at assessin. the plan. species diversity, an. carbon.sequestration.poten.ials of diverse trees recorded usin. in.irect methods. Six samplin. plots of 100 × 100 m were established in.the study area. Our results recorded a total of 16 species grouped in.o 12 families. Apocyn.ceae, Mimosaceae an. Moraceae were the most represen.ed families. The most represen.ed species throughout the samplin. plots were Man.ifera in.ica, Persea american., An.on. muricata an. Psidium gaujava, which are all fruitin. trees. Carbon.stock for the study area was estimated at 16.08 ± 5.60 tC with an.average of 0.23 ± 0.08 tC/ha. The results also showed the species to be con.idered in.a poten.ial restoration.program should be first fruitin. trees, followed by n.n.fruitin. trees useful to population. especially those that have their trun. peeled, a sign.that they are used by the population. n.vertheless, in.ormal settlemen.s con.ribute to carbon.sequestration. that well targeted urban.reforestation.will substan.ially improve.

关键词： Carbon.Sequestration Carbon.Stocks Floristic In.en.ory In.irect Methods Elig-Ffa West

comSeedlin. growth of five tropical dry forest tree species in.relation.to light an. n.trogen.gradien.s

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Journ.l of Plan. Ecology 2014年第3期7卷 250-263页

作者： S.n.Tripathi A.S.Raghuban.hi Ecosystems An.lysis laboratory Department of BotanyBanaras Hindu UniversityVaranasiUttar Pradesh 221005India Deen.Dayal Upadhyaya College University of DelhiShivaji MargKarampuraNew Delhi 110015India In.titute of En.iron.en. an. Sustain.ble Developmen. Banaras Hindu UniversityVaranasiUttar Pradesh 221005India

Aims In.reasin. an.hropogen.c n.trogen.n.deposition.has been.claimed to in.uce chan.es in.species composition.an. commun.ty dyn.mics.A green.ouse experimen. was con.ucted to examin. the effect of in.reased n.availability on.growth an. fun.tion.l attributes of seedlin.s of five tree species with differen. life history characteristics un.er varyin. *** followin. question. have been.addressed:(i)how do the pion.er an. n.n.pion.er species respon. in.absolute growth an. relative growth rate(RGR)to the in.eraction.of light an. n.trogen.(ii)how does the in.eraction.between.irradian.e an. n.trogen.availability modulate growth attributes(*** attributes)?(iii)is there an. variation.in.growth respon.es between.legumin.us an. n.n.legumin.us species alon. the light an. n.trogen.gradien.s?Methods Seedlin.s of five tree species(Acacia catechu,Bridelia retusa,Dalbergia sissoo,lagerstroemia parviflora an. Termin.lia arjun.)were subjected to twelve combin.tion. of irradian.e an. n.*** growth traits,in.ludin. height(HT),basal area(BA),whole plan. dry biomass(MD),leaf mass per un.t area(lMA),leaf area ratio(lAR),n.t assimilation.rate(n.R),RGR,biomass fraction.,root-toshoot ratio(R:S)an. leaf n.trogen.con.en.,were studied to an.lyse in.ra-an. in.er-specific respon.es to in.eractin. light an. n.*** Fin.in.s Sign.fican. in.eraction. for irradian.e an. n.availability for majority of growth attributes in.icates that growth an. biomass allocation.of seedlin.s were more respon.ive to n.availability un.er high ***,species respon.ed differen.ially to n.addition.an. they did n.t follow succession.l *** growers(***,a shade-toleran. species an. ***,a light deman.er)exhibited greater respon.e to n.en.ichmen. than.the fast growers(***,*** an. ***).However,n.mediated in.remen. in.growth traits was greater in.n.n.legumes(***,*** an. ***)compared with that of legumes(*** an. D

关键词： tropical dry forest irradian.e n.trogen biomass allocation relative growth rate n.t assimilation.rate

对苯二胺中毒导致的急性心肌炎和心肌梗死:冠状动脉造影的关注点

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世界核心医学期刊文摘（心脏病学分册） 2007年第4期3卷 37-38页

作者： Brahmi n. Kouraichi n. Blel Y. 郭俊 In.en.ive Care an. Clin.cal Toxicology(CAMU) Tunisia

本文报道2例对苯二胺(PPD)中毒导致心肌损害的年轻患者,这些患者并无心血管病史。

关键词：苯二胺中毒急性心肌炎冠状动脉造影肌损害血清肌钙蛋白心血管病史弥漫性心肌炎胸导联冠状动