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Hematological picture of pediatric Sudanese patients with visceral leishmaniasis and prediction of leishmania donovani parasite load

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World Journal of Clinical Cases 2024年第30期12卷 6374-6382页

作者： Zeinab Ibrahim Ahmed Elnoor Omaima Abdelmajeed Alamin mustafa Thuraya Gasim Shima Algam Mohamed Musa Abdelrahman Hamza Abdelmoneim Islamia Ibrahim Ahmed Omer Hiba Awadelkareem Osman Fadl Department of Pathology Faculty of MedicineOmdurman Ahilia UniversityOmdurmanKhartoumSudan Mohammed Alamin Hamid Pediatric Hospital Omdurman KhartoumSudan Department of Hematology and Blood Transfusion Medicine Federal Ministry of HealthKhartoumSudan Department of Pediatrics Faculty of MedicineOmdurman Islamic UniversityOmdurmanKhartoumSudan Tropical Diseases Teaching Hospital OmdurmanKhartoumSudan Faculty of Medicine Al-Neelain UniversityKhartoumSudan Faculty of Medicine Omdurman Islamic UniversityOmdurmanKhartoumSudan Department of Pediatrics Faculty of MedicineUniversity of Science and TechnologyKhartoumSudan Department of Hematology Faculty of Medical Laboratory SciencesAl-Neelain UniversityKhartoumSudan

BACKGROUND Visceral leishmaniasis(VL)is a systemic protozoan infection caused by Leishmania donovani(***)and transmitted by sand flies,causing macrophage invasion in the liver,spleen,and bone *** of VL is currently based on clinical signs,symptoms,and specific in-vitro markers and bone marrow ***,VL's specific hematological and bone marrow manifestation in Sudanese pediatric patients is not well *** To examine the blood and bone marrow characteristics in pediatric patients from Sudan who have *** This is a retrospective hospital-based study with a sample of 107 consecutive Sudanese pediatric *** data focused on hematological and bone marrow *** included only the completed records of the pediatric patients with VL in the Tropical Disease Teaching Hospital in Khartoum,Sudan from the period of 2016 to *** The majority of pediatric patients included in this study are below 5-years-old(n=59,55.2%).Moreover,anemia,thrombocytopenia,and leukopenia were among the prevalent characteristics in the population under *** further analyze the data,we developed a machine learning model using boosted forest algorithms to predict *** parasites load,with a mean accuracy of 0.88 for the training dataset and an accuracy of 0.46,0.50,and 0.74 for mild,moderate,and severe *** parasite load in the validation *** This study shows that the most common bone marrow change among Sudanese VL children was increased chronic inflammatory cells(n=88,82.2%)with present macrophage hemophagocytes(n=103,96.3%).While anemia and thrombocytopenia were the most common hematological *** results will hopefully lead to an early diagnosis and hence better management for Sudanese pediatric patients with suspected VL.

关键词： Machine learning Bone marrow Hematological changes Tropical diseases Leishmania donovani Visceral leishmaniasis

An ethnobotanical study of medicinal plants in Güce district,north-eastern Turkey

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Plant Diversity 2022年第6期44卷 577-597页

作者： mustafa Karakose Giresun University Espiye Vocational SchoolProgramme of Medicinal and Aromatic PlantsEspiyeGiresun28600Turkey

This study aims to identify medicinal plants traditionally used to treat diseases by local people living in Güce district,north-eastern *** study was carried out between 2018 and 2021 using a two-part semi-structured,open-ended questionnaire with 165 local *** were analysed using use-report,frequency of citation,and informant consensus *** identified 128 vascular medicinal plant taxa belonging to 54 families and 106 *** most common plant taxa belong to Rosaceae(16 taxa/12.5%),Asteraceae(12 taxa/9.4%),and Lamiaceae(9 taxa/7%)*** most frequently used preparation method reported was decoction(39.8%);the most commonly utilized plant parts were leaves(40.3%).Statistical analysis reveals that women in Güce district(df?163,p?0.043<0.05)possess the most traditional *** highest frequency of citation(61)and use report(92)were recorded for Tilia rubra ***,and the highest informant consensus factors were cited for respiratory system disorders(0.86),digestive system disorders(0.73),and skin disorders(0.71).This study reported nine plant taxa as medicinal plants for the first time,and documented a total of 293 new therapeutic ***,the study indicates that the transfer of traditional knowledge to future generations is limited(F?3.355,p?0.020).Action should be taken as soon as possible to preserve existing traditional knowledge and to ensure its transfer to future generations.

关键词： Colchic Ethnobotany Informant consensus factor Frequency of citation Traditional medicine Use-record

EFFECT OF VINYL ACETATE CONTENT ON THE MECHANICAL PROPERTIES AND MORPHOLOGICAL STRUCTURES OF POLYPROPYLENE

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Chinese Journal of Polymer Science 2006年第1期24卷 29-34页

作者： mustafa ksüz Technical Education Faculty Marmara University 34722 GztepeIstanbulTurkey

The effect of vinyl acetate （VA） content in ethylene vinyl acetate （EVA） copolyrner on the mechanical properties of polypropylene was investigated. Three different EVA copolymers with concentrations of 3 wt%, 6 wt%, 9 wt%, 12 wt% and 15 wt%, were blended to polypropylene. The mechanical properties such as yield and tensile strengths, elastic modulus, Izod impact strength, hardness and melt flow index of the blends were investigated. Relationship between type of vinyl acetate and concentrations, mechanical, MFI and morphological properties were explored.

关键词： Compound Mechanical properties Morphology.

Decomposition method for solving parabolic equations in finite domains

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2005年第10期6卷 1058-1064页

作者： INC mustafa Department of Mathematics Firat University Elazig 23119Turkey

This paper presents a comparison among Adomian decomposition method (ADM), Wavelet-Galerkin method (WGM), the fully explicit (1,7) finite difference technique (FTCS), the fully implicit (7,1) finite difference method (BTCS), (7,7) Crank-Nicholson type finite difference formula (C-N), the fully explicit method (1,13) and 9-point finite difference method, for solving parabolic differential equations with arbitrary boundary conditions and based on weak form functionals in finite domains. The problem is solved rapidly, easily and elegantly by ADM. The numerical results on a 2D transient heat conducting problem and 3D diffusion problem are used to validate the proposed ADM as an effective numerical method for solving finite domain parabolic equations. The numerical results showed that our present method is less time consuming and is easier to use than other methods. In addition, we prove the convergence of this method when it is applied to the nonlinear parabolic equation.

关键词： Adomian decomposition method (ADM) Adomian polynomials Parabolic differential equations

Parameter Estimation Based on Censored Data under Partially Accelerated Life Testing for Hybrid Systems due to Unknown Failure Causes

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Computer Modeling in Engineering & Sciences 2022年第3期130卷 1239-1269页

作者： mustafa Kamal Department of Basic Sciences College of Science and Theoretical StudiesSaudi Electronic UniversityDammam32256Saudi Arabia

In general,simple subsystems like series or parallel are integrated to produce a complex hybrid *** reliability of a system is determined by the reliability of its constituent *** is often extremely difficult or impossible to get specific information about the component that caused the system to *** failure causes are instances in which the actual cause of systemfailure is *** the other side,thanks to current advanced technology based on computers,automation,and simulation,products have become incredibly dependable and trustworthy,and as a result,obtaining failure data for testing such exceptionally reliable items have become a very costly and time-consuming ***,because of its capacity to produce rapid and adequate failure data in a short period of time,accelerated life testing(ALT)is the most utilized approach in the field of product reliability and life *** on progressively hybrid censored(PrHC)data froma three-component parallel series hybrid system that failed to owe to unknown causes,this paper investigates a challenging problem of parameter estimation and reliability assessment under a step stress partially accelerated life-test(SSPALT).Failures of components are considered to follow a power linear hazard rate(PLHR),which can be used when the failure rate displays linear,decreasing,increasing or bathtub failure *** Tempered random variable(TRV)model is considered to reflect the effect of the high stress level used to induce early failure *** maximum likelihood estimation(MLE)approach is used to estimate the parameters of the PLHR distribution and the acceleration factor.A variance covariance matrix(VCM)is then obtained to construct the approximate confidence intervals(ACIs).In addition,studentized bootstrap confidence intervals(ST-B CIs)are also constructed and compared with ACIs in terms of their respective interval lengths(ILs).Moreover,a simulation study is conducted to demonstrate the

关键词： Step stress partially accelerated life test progressive hybrid censoring data masking power linear hazard rate distribution hybrid system

New Compacton Solutions of Nonlinearly Dispersive R（m, n） Equations

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Communications in Theoretical Physics 2006年第3期45卷 389-394页

作者： mustafa Inc Department of Mathematics Firat University 23119 Elazig Turkiye

In this paper, we establish exact solutions for the .R（m,n） equations by using an sn-cn metnou,As a result, abundant new cornpactons, i,e, solitons with the absence of infinite wings, new type of Jacobi elliptic function, solitary wave and periodic wave solutions, of this equation are obtained with minimal calculations. The properties of the R（m, n） equations are shown in figures.

关键词： R(m n) equation compacton solution soliton

Equivalence of Ratio and Residual Approaches in the Homotopy Analysis Method and Some Applications in Nonlinear Science and Engineering

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Computer Modeling in Engineering & Sciences 2019年第7期120卷 63-81页

作者： mustafa Turkyilmazoglu Department of Mathematics Hacettepe University06532-BeytepeAnkaraTURKEY

A ratio approach based on the simple ratio test associated with the terms of homotopy series was proposed by the author in the previous *** was shown in the latter through various comparative physical models that the ratio approach of identifying the range of the convergence control parameter and also an optimal value for it in the homotopy analysis method is a promising alternative to the classically used h-level curves or to the minimizing the residual(squared)error.A mathematical analysis is targeted here to prove the equivalence of both the ratio approach and the traditional residual approach,especially regarding the root-finding problems via the homotopy analysis *** are provided to further justify ***,it is conjectured that every nonlinear differential equation can be considered as a root-finding problem by plugging a parameter in it from a physical *** examples from the boundary and initial and value problems are provided to verify this ***,besides the advantages as deciphered in the previous publications,the feasibility of the ratio approach over the traditional residual approach is made clearer in this paper.

关键词： Homotopy analysis method convergence control parameter optimum value ratio approach residual approach

Statistical and Geometrical Way of Model Selection for a Family of Subdivision Schemes

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Chinese Annals of Mathematics,Series B 2017年第5期38卷 1077-1092页

作者： Ghulam mustafa Department of Mathematics The Islamia University of BahawalpurBahawalpur 63100Pakistan

The objective of this article is to introduce a generalized algorithm to produce the m-point n-ary approximating subdivision schemes(for any integer m, n ≥ 2). The proposed algorithm has been derived from uniform B-spline blending functions. In particular, we study statistical and geometrical/traditional methods for the model selection and assessment for selecting a subdivision curve from the proposed family of schemes to model noisy and noisy free data. Moreover, we also discuss the deviation of subdivision curves generated by proposed family of schemes from convex polygonal curve. Furthermore, visual performances of the schemes have been presented to compare numerically the Gibbs oscillations with the existing family of schemes.

关键词： Approximating subdivision schemes B-spline blending function Convex polygon Statistical and geometrical methods Model selection andassessment

Two-Dimensional Electrophoretic Analysis of Soluble Leaf Proteins of a Salt-sensitive （Triticum aestivum） and a Salt-tolerant （T. durum） Cultivar in Response to NaCI Stress

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Journal of Integrative Plant Biology 2007年第7期49卷 975-981页

作者： mustafa YILDIZ Afyon Kocatepe University Faculty of Science and Arts Department of Biology Afyonkarahisar 03200 Turkey

In this research, 3-day-old etiolated wheat seedlings of Triticum aestivum L. cv. Ceyhan-99 （salt-sensitive） and T. durum Desf. cv. Firat-93 （salt-tolerant） were grown in control and salt （150 mmol/L NaCl） treatments at a 15/25℃ temperature regime in the light for 12 days. Soluble proteins extracted from the first leaf tissues of two cultivars were analyzed by twodimensional （2-D） electrophoresis in order to detect NaCl-induced changes. The soluble leaf protein profiles of cultivars were observed to be similar. However, quantitative differences in 74 proteins were detected in the salt treatment group, compared to the control. Among the 74 protein spots, 14 were common for two cultivars. As a result of NaCl treatment, two low-molecular-weight （LMW） proteins （28.9 and 30.0 kDa） and one intermediate-molecular-weight （IMW） protein （44.3 kDa） in cv. Ceyhan-99 and six LMW proteins （18.6, 19.4, 25.7, 25.9, 26 and 27.6 kDa） in cv. Firat-93 were newly synthesized. The newly synthesized proteins were specific to each cultivar. In the Firat-93 cultivar, four proteins with LMW （24.8-27.9 kDa） were completely lost in NaCl treatment. Moreover, these four protein spots were not observed in both protein profiles of cv. Ceyhan-99. Most of these proteins were in acidic character （pl 〈6.0-6.9） and low molecular weight （〈31.6 kDa）. It is suggested that the newly synthesized or completely lost LMW proteins may be important for cultivars differing in sensitivity towards NaCl.

关键词： NaCl stress soluble leaf proteins Triticum aestivum Triticum durum two-dimensional electrophoretic analysis.