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Lubiprostone induced ischemic colitis

World Journal of Gastroenterology 2013年第2期19卷 299-303页

作者： muhammed sherid Humberto Sifuentes Salih Samo Parakkal Deepak Subbaramiah Sridhar Department of Internal Medicine Division of GastroenterologySaint Francis HospitalEvanstonIL 60202United States Section of Gastroenterology and Hepatology Medical College of GeorgiaGeorgia Health Sciences UniversityAugustaGA 30912United States Department of Internal Medicine Division of GastroenterologyNorthShore University HealthSystemHighland ParkIL 60035United States

Ischemic colitis accounts for 6%-18% of the causes of acute lower gastrointestinal *** is often multifactorial and more commonly encountered in the *** medications have been implicated in the development of colonic *** report a case of a 54-year old woman who presented with a two-hour history of nausea,vomiting,abdominal pain,and bloody *** patient had recently used lubiprostone with close temporal relationship between the increase in the dose and her symptoms of rectal *** radiologic,colonoscopic and histopathologic findings were all consistent with ischemic *** condition improved without any serious complications after the cessation of *** is the first reported case of ischemic colitis with a clear relationship with lubiprostone(Naranjo score of 10).Clinical vigilance for ischemic colitis is recommended for patients receiving lubiprostone who are presenting with abdominal pain and rectal bleeding.

关键词： Lubiprostone Ischemic colitis Gastrointestinal bleeding Rectal bleeding Colonoscopy

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Radiation therapy-induced aortoesophageal fistula:a case report and review of literature

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Gastroenterology Report 2016年第2期4卷 165-167,I0003页

作者： Malav P.Parikh muhammed sherid Sreelakshmi Panginikkod Harsh A.Rawal Venu Gopalakrishnan Department of Internal Medicine Division of Gastroenterology and HepatologyPresence Saint Francis HospitalEvanstonIllinoisUSA Department of Gastroenterology and Hepatology Georgia Regents UniversityAugustaGeorgiaUSA Department of Internal Medicine Government Medical College CalicutKeralaIndia

Aortoesophageal fistula(AEF)is a rare cause of massive upper gastrointestinal *** aortic aneurysm,esophageal foreign body,esophageal cancer and post-surgical complications are common causes of AEF;however,AEF induced by radiation therapy is a rare phenomenon and seldom described in the *** is a catastrophic condition which requires rapid implementation of resuscitative measures,broad-spectrum antibiotics and surgical or endovascular *** endovascular aortic repair(TEVAR)is a newer and less invasive technique,which helps to achieve rapid hemostasis in patients with severe hemodynamic instability and offers advantages over conventional repair of the aorta in emergency *** initial TEVAR should be followed up with a more definitive surgical repair of the aorta and the esophagus,to lower the mortality rate and achieve better *** describe here a case of a seventyyear-old male who presented with massive upper gastrointestinal bleeding due to AEF induced by radiation therapy,and his subsequent successful initial management with TEVAR.

关键词： gastrointestinal hemorrhage aortoesophageal fistula radiation therapy transthoracic endovascular aortic repair

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Ischemic colitis induced by the newly reformulated multicomponent weight-loss supplement Hydroxycut~

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World Journal of Gastrointestinal Endoscopy 2013年第4期5卷 180-185页

作者： muhammed sherid Salih Samo Samian Sulaiman Joseph H Gaziano Department of Internal Medicine Division of Gastroenterology CGH Medical Center Department of Internal Medicine Division of Gastroenterology Saint Francis Hospital

Ischemic colitis accounts for 6%-18% of causes of acute lower gastrointestinal bleeding. It is more often multifactorial and more common in elderly. Drugs are considered important causative agents of this disease with different mechanisms. In this paper, we describe a 37-year-old otherwise healthy female presented with sudden onset diffuse abdominal pain and bloody stool. Radiologic, colonoscopic and histopathologic findings were all consistent with ischemic colitis. Her only suspected factor was hydroxycut which she had been taking for a period of 1 mo prior to her presentation. Her condition improved uneventfully after cessation of hydroxycut, bowel rest, intravenous hydration, and antibiotics. This is a first case of ischemic colitis with clear relationship with hydroxycut use (Naranjo score of 7). Our case demonstrates the importance of questioning patients regarding the usage of dietary supplements; especially since many patients consider them safe anddo not disclose their use voluntarily to their physicians. Hydroxycut has to be considered as a potential trigger for otherwise unexplained ischemic colitis.

关键词： Hydroxycut Weight-loss supplement Herbal Ischemic colitis Gastrointestinal bleeding Colonoscopy

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