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A Porous Nano-Micro-Composite as a High-Performance Bi-Functional air Electrode with Remarkable Stability for Rechargeable Zinc-air Batteries

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Nano-Micro Letters 2020年第10期12卷 87-102页

作者： yasir Arafat muhammad Rizwan Azhar Yijun Zhong Xiaomin Xu Moses OTadé Zongping Shao WA School of Mines:Minerals Energy and Chemical Engineering(WASM‑MECE)Curtin UniversityPerthWA 6845Australia School of Engineering Edith Cowan UniversityPerthWA 6027Australia State Key Laboratory of Materials‑Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 210009JiangsuPeople’s Republic of China

The development of bi-functional electrocatalyst with high catalytic activity and stable performance for both oxygen evolution/reduction reactions(OER/ORR)in aqueous alkaline solution is key to realize practical application of zinc-air batteries(ZABs).In this study,we reported a new porous nano-micro-composite as a bifunctional electrocatalyst for ZABs,devised by the in situ growth of metal-organic framework(MOF)nanocrystals onto the micrometersized Ba0.5Sr0.5Co0.8Fe0.2O3(BSCF)perovskite *** carbonization,MOF was converted to porous nitrogen-doped carbon nanocages and ultrafine cobalt oxides and CoN4 nanoparticles dispersing inside the carbon nanocages,which further anchored on the surface of BSCF *** homogeneously dispersed BSCF perovskite particles in the surfactant;subsequently,ZIF-67 nanocrystals were grown onto the BSCF *** this way,leaching of metallic or organic species in MOFs and the aggregation of BSCF were effectively suppressed,thus maximizing the number of active sites for improving *** BSCF in turn acted as catalyst to promote the graphitization of carbon during pyrolysis,as well as to optimize the transition metal-tocarbon ratio,thus enhancing the ORR catalytic activity.A ZAB fabricated from such air electrode showed outstanding performance with a potential gap of only 0.83 V at 5 mA cm-2 for OER/***,no obvious performance degradation was observed for the continuous charge-discharge operation for 1800 cycles over an extended period of 300 h.

关键词： BSCF perovskites ZIF-67 Porous carbon Zn-air batteries Oxygen evolution reaction Oxygen reduction reaction

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Prediction of promiscuous T cell epitopes in RNA dependent RNA polymerase of Chikungunya virus

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Asian Pacific Journal of Tropical Medicine 2017年第8期10卷 825-829页

作者： yasir Waheed Sher Zaman Safi Muzammil Hasan Najmi Hafsa Aziz muhammad Imran Foundation University Medical College Foundation University IslamabadDHA-I Islamabad(44000)Pakistan Interdisciplinary Research Centre in Biomedical Materials(IRCBM) COMSATS Institute of Information TechnologyLahore CampusLahorePakistan Nuclear Medicine Oncology and Radiotherapy Institute Islamabad Islamabad(44000)Pakistan Department of Medical Laboratory Sciences(DMLS) Faculty of Health and Allied Sciences(FHAS)Imperial College of Business Studies(ICBS)LahorePakistan Department of Microbiology University of Health SciencesLahorePakistan

Objective: To explore RNA dependent RNA polymerase of Chikungunya virus(CHIKV) and develop T cell based epitopes with high antigenicity and good binding affinity for the human leukocyte antigen(HLA) classes as targets for epitopes based CHIKV vaccine. Methods: In this study we downloaded 371 non-structural protein 4 protein sequences of CHIKV belonging to different regions of the world from the US National Institute of Allergy and Infectious Diseases(NIAID) virus pathogen resource database. All the sequences were aligned by using CLUSTALW software and a consensus sequence was developed by using Uni Pro U Gene Software version 1.2.1. PropredⅠand Propred software were used to predict HLAⅠ and HLAⅡ binding promiscuous epitopes from the consensus sequence of non-structural protein 4 protein. The predicted epitopes were analyzed to determine their antigenicity through Vaxijen server version 2.0. All the HLAⅠ binding epitopes were scanned to determine their immunogenic potential through the Immune Epitope Database(IEDB). All the predicted epitopes of our study were fed to IEDB database to determine whether they had been tested earlier. Results: Twenty two HLA class Ⅱ epitopes and eight HLA classⅠepitopes were predicted. The promiscuous epitopes WMNMEVKII at position 486–494 and VRRLNAVLL at 331–339 were found to bind with 37 and 36 of the 51 HLA class Ⅱ alleles respectively. Epitope MANRSRYQS at position 58–66 and epitopes YQSRKVENM at positions 64–72 were predicted to bind with 12 and 9 HLAⅠI alleles with antigenicity scores of 0.754 9 and 1.013 0 respectively. Epitope YSPPINVRL was predicted to bind 18 HLAⅠ alleles and its antigenicity score was 1.425 9 and immunogenicity score was 0.173 83. This epitope is very useful in the preparation of a universal vaccine against CHIKV infection. Conclusions: Epitopes reported in this study showed promiscuity, antigenicity as well as good binding affinity for the HLA classes. These epitopes will provide the baseline for development

关键词： Chikungunya 病毒 Epitope 疫苗 HLA 绑定 T 房间 epitopes

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Plant extract-loaded bacterial cellulose composite membrane for potential biomedical applications

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Journal of Bioresources and Bioproducts 2021年第1期6卷 26-32页

作者： Atiya Fatima Sumayia yasir MohdShariq Khan Sehrish Manan muhammad Wajid Ullah Mazhar Ul-Islam Department of Chemical Engineering College of EngineeringDhofar UniversitySalalahSultanate of Oman Department of Biomedical Engineering Huazhong University of Science and TechnologyWuhan 430074China

Bacterial cellulose(BC)has been extensively explored as biomaterial for various biomedical applications owing to its non-toxic nature and unique structural morphology and impressive physicochemical and mechanical ***,its high production cost and lack of antimicrobial activity have restricted its large-scale production and therapeutic ***,the current study is aimed to devise a strategy for low-cost BC production and develop its composite with bioactive materials to bless it with antimicrobial ***,5 mm thick reticulated fibrous and highly porous BC was produced by utilizing the wasted rotten tomatoes as the production *** produced bacterial cellulose waste(BCW)(i.e.,produced from wastes)was ex-situ modified with bioactive plant extract(PE)obtained from Euclea schimperi,and the bactericidal activity of the developed BCW/PE was evaluated against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli through disc diffusion and colony forming unit(CFU)count *** BCW/PE composite showed high bactericidal activities against *** and produced clear inhibition zone whereas negligible activity was observed against ***,indicating its bactericidal activity mainly against the Gram-positive ***,this study illustrates that there is a huge potential for developing valuable biomaterials from food wastes and utilizing their liquid holding capabilities for value-added applications in medical and pharmaceutical fields.

关键词： Bacterial cellulose Food waste Plant extract Bactericidal activity Biomedical application

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Feasibility-Guided Constraint-Handling Techniques for Engineering Optimization Problems

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Computers, Materials & Continua 2021年第6期67卷 2845-2862页

作者： muhammad Asif Jan yasir Mahmood Hidayat Ullah Khan Wali Khan Mashwani muhammad Irfan Uddin Marwan Mahmoud Rashida Adeeb Khanum Ikramullah Noor Mast Institute of Numerical Sciences Kohat University of Science&TechnologyKohatPakistan Department of Economics Abbottabad University of Science&TechnologyAbbottabadPakistan Institute of Computing Kohat University of Science&TechnologyKohatPakistan Faculty of Applied Studies King Abdulaziz UniversityJeddahSaudi Arabia Jinnah College for Women University of PeshawarPeshawarPakistan Department of Physics Kohat University of Science&TechnologyKohatPakistan

The particle swarm optimization(PSO)algorithm is an established nature-inspired population-based meta-heuristic that replicates the synchronizing movements of birds and *** is essentially an unconstrained algorithm and requires constraint handling techniques(CHTs)to solve constrained optimization problems(COPs).For this purpose,we integrate two CHTs,the superiority of feasibility(SF)and the violation constraint-handling(VCH),with a *** CHTs distinguish feasible solutions from infeasible ***,in SF,the selection of infeasible solutions is based on their degree of constraint violations,whereas in VCH,the number of constraint violations by an infeasible solution is of more ***,a PSO is adapted for constrained optimization,yielding two constrained variants,denoted SF-PSO and *** SF-PSO and VCH-PSO are evaluated with respect to ve engineering problems:the Himmelblau’s nonlinear optimization,the welded beam design,the spring design,the pressure vessel design,and the three-bar truss *** simulation results show that both algorithms are consistent in terms of their solutions to these problems,including their different available *** of the SF-PSO and the VCHPSO with other existing algorithms on the tested problems shows that the proposed algorithms have lower computational cost in terms of the number of function evaluations *** also report our disagreement with some unjust comparisons made by other researchers regarding the tested problems and their different variants.

关键词： Constrained evolutionary optimization constraint handling techniques superiority of feasibility violation constraint-handling technique swarm based evolutionary algorithms particle swarm optimization engineering optimization proble

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Overview of Strain Characterization in Relation to Serological and Molecular Detection of Citrus tristeza Closterovirus

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Phyton-International Journal of Experimental Botany 2021年第4期90卷 1063-1074页

作者： yasir Iftikhar Mazhar Abbas Mustansar Mubeen muhammad Zafar-ul-Hye Faheema Bakhtawar Sonum Bashir Ashara Sajid muhammad Asif Shabbir Department of Plant Pathology College of AgricultureUniversity of SargodhaSargodha40100Pakistan Institute of Horticultural Sciences University of Agriculture FaisalabadFaisalabad38000Pakistan State Key Laboratory of Agricultural Microbiology and Provincial Key Laboratory of Plant Pathology of Hubei Province College of Plant Science and TechnologyHuazhong Agricultural UniversityWuhan430070China Department of Soil Science Faculty of Agricultural Sciences and TechnologyBahauddin Zakariya UniversityMultan60800Pakistan

Tristeza is a devastating viral disease in all the citrus growing countries throughout the world and has killed millions of citrus trees in severely affected *** citrus species grafted on sour orange rootstock are affected by this ***,the sweet orange,grapefruit and lime trees grafted on sour orange exhibit severe symptoms like quick decline,vein clearing,pin holing,bark scaling and degeneration leading to variable *** expression of Citrus tristeza virus(CTV)in different hosts has been attributed to virus isolates which are from severe to *** serological and molecular assays have been deployed to differentiate the strains of *** tristeza virus is diversified towards its strains on the basis of biological,serological and molecular *** expression is due to genetic alteration and different molecular basis have now been adopted for strain *** review will give a brief idea about the different CTV isolates,their characterization based on nucleic acid and serological *** methods along with salient features for strain characterization has also been *** review will also open the new aspects towards formulation of management strategies through different detection techniques.

关键词： Citrus tristeza virus symptomology detection serology isolates and host rang

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Predictors of response to antiviral therapy in patients with chronic hepatitis C from Pakistani population

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Chinese Medical Journal 2011年第9期124卷 1333-1337页

作者： Hafsa Aziz muhammad Amin Athar Shahnaz Murtaza Javaid Irfan yasir Waheed Iram Bilal Abida Raza Nuclear Medicine Oncology and Radiotherapy Institute Islamabad Punjab University Lahore Pakistan Institute of Biochemistry & Biotechnology Punjab University Lahore Pakistan NUST Center of Virology and Immunology National University of Sciences and Technology Islamabad Pakistan COMSATS Institute Islamabad Pakistan

Background Hepatitis C virus （HCV） constitutes a major public health issue around the world, especially in developing countries like Pakistan. In this study, we assessed outcome of interferon （INF） treatment in chronic hepatitis C patients categorized by gender, age, and viral *** In this study, 750 HCV positive patients with genotype 3 were selected, out of which 616 completed the entire treatment. Their personal history, pro-treatment HCV RNA and serum alanine transaminase （ALT） was *** were treated with combination therapy of INF-α 2b three million units （thrice a week） plus ribavirin （1000-1200mg per day） for 24 weeks. After 24 weeks their HCV RNA and serum ALT level was *** Out of the 616 patients, 391 （63.5%） responded to therapeutic regimen （INF-α 2b plus ribavirin）. Among the responders, 27.1% were men and 36.4% were women. Best treatment response was observed in patients having Iow viral load ＜8×105 IU/ml and age ≤40 years than patients having Iow viral load and age ＞40 years （73.2% vs. 60.3%, P=0.05）.Conclusions Better response to IFN-α 2b plus ribavirin was observed in patients with lower viral RNA and younger *** suggests that all patients considered for treatment should have quantification of serum HCV RNA level. The result can be used to counsel patients on the likelihood of response and may influence the patient＇s decision on treatment.

关键词： hepatitis C interferon ribavirin

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Assessment of sunflower germplasm for phytoremediation of lead-polluted soil and production of seed oil and seed meal for human and animal consumption

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Journal of Environmental Sciences 2020年第1期32卷 24-38页

作者： Afsheen Zehra Zulfiqar Ali Sahito Wenbin Tong Lin Tang yasir Hamid muhammad Bilal Khan Zarina Ali Beena Naqui Xiaoe Yang Ministry of Education(MOE)Key Laboratory of Environmental Remediation and Ecosystem Health College of Environmental and Resources ScienceZhejiang UniversityHangzhou 310058China Department of Botany Federal Urdu University of ArtsScience and TechnologyKarachi 75300Pakistan Technical Extension Station of Soil Fertilizer and Rural Energy QujiangQuzhou 324000China PCSIR Laboratories Complex KarachiDr Salimuzzaman RoadKarachi 75280Pakistan

Phytoremediation is a valuable technology for mitigating soil contamination in agricultural lands,but phytoremediation without economic revenue is unfeasible for land owners and *** use of crops with high biomass and bioenergy for phytoremediation is a unique strategy to derive supplementary benefits along with remediation ***(Helianthus annuus L.)is a high-biomass crop that can be used for the phytoremediation of polluted lands with additional advantages(biomass and oil).In this study,40 germplasms of sunflower were screened in field conditions for phytoremediation with the possibility for oil and meal *** study was carried out to the physiological maturity *** studied germplasms mopped up substantial concentrations of Pb,with maximum amounts in shoot>root>seed *** phytoextraction efficiency of the germplasm was assessed in terms of the Transfer factor(TF),Metal removal efficiency(MRE)and Metal extraction ratio(MER).Among all assessed criteria,GP.8585 was found to be most appropriate for restoring moderately Pb-contaminated soil accompanied with providing high biomass and high yield *** Pb content in the oil of GP.8585 was below the Food safety standard of China,with 59.5% oleic acid and 32.1% linoleic ***,amino acid analysis in meal illustrated significant differences among essential and nonessential amino *** acid was found in the highest percentage(22.4%),whereas cysteine in the lowest percentage(1.3%).Therefore,its efficient phytoextraction ability and good quality edible oil and meal production makes GP.8585 the most convenient sunflower germplasm for phytoremediation of moderately Pb-contaminated soil,with fringe benefits to farmers and landowners.

关键词： Heavy metal Soil contamination Metal removal efficiency(MRE) Germplasm(GP) Phytoextraction Edible oil Fatty acids(FA) Amino acids(AAs)

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A gelatin-based artificial SEI for lithium deposition regulation and polysulfide shuttle suppression in lithium-sulfur batteries

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Journal of Energy Chemistry 2021年第1期30卷 310-317,I0010页

作者： Naseem Akhtar Xiaogang Sun muhammad yasir Akram Fakhar Zaman Weikun Wang Anbang Wang Long Chen Hao Zhang Yuepeng Guan Yaqin Huang Beijing Key Laboratory of Electrochemical Process and Technology for Materials Key Laboratory of Biomedical Materials of Natural MacromoleculesMinistry of EducationBeijing Advanced Innovation Center for Soft Matter Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029China Research Institute of Chemical Defense Beijing 100191China

Lithium-sulfur(Li-S) battery is one of the best candidates for the next-generation energy storage system due to its high theoretical capacity(1675 mA h-1),low cost and environment ***,lithium(Li) dendrites formation and polysulfide shuttle effect are two major challenges that limit the commercialization of Li-S *** we design a facile bifunctional interlayer of gelatin-based fibers(GFs),aiming to protect the Li anode surface from the dendrites growth and also hinder the polysulfide shuttle *** reveal that the 3D structural network of GFs layer with abundant polar sites helps to homogenize Li-ion flux,leading to uniform Li-ion ***,the polar moieties also immobilize the lithium polysulfides and protect the Li metal from the *** a result,the anodeprotected batteries have shown significantly enhanced performance.A high coulombic efficiency of 96% after 160 cycles has been achieved in the Li-Cu half *** Li-Li symmetric cells exhibit a prolonged lifespan for 800 h with voltage hysteresis(10 mV).With the as-prepared GFs layer,the Li-S battery shows approximately 14% higher capacity retention than the pristine battery at 0.5 C after 100 *** work presents that this gelatin-based bi-functional interlayer provides a viable strategy for the manufacturing of advanced Li-S batteries.

关键词： Bifunctional layer Gelatin-based fibers Shuttle effect Artificial SEI Lithium-sulfur battery

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Yellow Vein Mosaic Disease in Okra(Abelmoschus esculentus L.):An Overview on Causal Agent,Vector and Management

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Phyton-International Journal of Experimental Botany 2021年第6期90卷 1573-1587页

作者： Mustansar Mubeen yasir Iftikhar Aqleem Abbas Mazhar Abbas muhammad Zafar-ul-Hye Ashara Sajid Faheema Bakhtawar Department of Plant Pathology College of AgricultureUniversity of SargodhaSargodha40100Pakistan State Key Laboratory of Agricultural Microbiology and Provincial Key Laboratory of Plant Pathology of Hubei Province College of Plant Science and TechnologyHuazhong Agricultural UniversityWuhan430070China Department of Agriculture and Agribusiness Management University of KarachiKarachi75270Pakistan Department of Soil Science Faculty of Agricultural Sciences and TechnologyBahauddin Zakariya UniversityMultan60800Pakistan

Okra(Abelmoschus esculentus L.)belongs to the Malvaceae family and is one of the most essential and popular vegetables *** is rich in proteins,carbohydrates,and *** and biotic factors threaten okra *** yellow vein mosaic disease(OYVMD)is the most destructive disease of *** causal agent,[i.e.,Okra yellow vein mosaic virus(OYVMV)]of this disease belongs to the family Geminiviridae and genus *** is a monopartite with additional ssDNA *** virus has two components DNA-A for protein coding and DNA-B for symptoms *** transmits OYVMV in persistent *** symptoms of OYVMV infected okra plants are chlorosis,dwarfing,and yellowing of veins and *** temperatures with moderate rainfall enhance the development of OYVMV disease and the whitefly ***,high humidity with low temperature and rainfall has no significant role in developing the OYVMD and whitefly ***,the virus also affects the secondary metabolites in the infected okra *** virus can be managed through various strategies including the application of plant defense activators,the development of resistant varieties and by controlling its vector via pesticides and plant *** plant defense activators such as monopotassium phosphate(KH2PO),salicylic acid,benzoic acid,and citric acid enhance resistance in okra against *** addition,the resistance to OYMVD can also be achieved by successfully incorporating high yielding but resistant cultivars of acceptable *** this review,we have discussed history,economic impact,symptomology,disease development under a natural environment,genetics and management of OYVMV.

关键词： Okra OYVMV symptoms vectors epidemiological factors management

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Enhanced Fingerprinting Based Indoor Positioning Using Machine Learning

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Computers, Materials & Continua 2021年第11期69卷 1631-1652页

作者： muhammad Waleed Pasha Mir yasir Umair Alina Mirza Faizan Rao Abdul Wakeel Safia Akram Fazli Subhan Wazir Zada Khan Department of Electrical Engineering National University of Sciences and TechnologyIslamabad44000Pakistan Department of Computer Engineering National University of Modern Languages(NUML)Islamabad44000Pakistan Faculty of Computing Capital University of Science and TechnologyIslamabad44000Pakistan

Due to the inability of the Global Positioning System(GPS)signals to penetrate through surfaces like roofs,walls,and other objects in indoor environments,numerous alternative methods for user positioning have been *** those,the Wi-Fi fingerprinting method has gained considerable interest in Indoor Positioning Systems(IPS)as the need for lineof-sight measurements is minimal,and it achieves better efficiency in even complex indoor *** and online are the two phases of the fingerprinting *** researchers have highlighted the problems in the offline phase as it deals with huge datasets and validation of Fingerprints without pre-processing of data becomes a *** learning is used for the model training in the offline phase while the locations are estimated in the online *** researchers have considered the concerns in the offline phase as it deals with huge datasets and validation of Fingerprints becomes an *** learning algorithms are a natural solution for winnowing through large datasets and determining the significant fragments of information for localization,creating precise models to predict an indoor *** training sets are a key for obtaining better results in machine learning ***,an existing WLAN fingerprinting-based multistory building location database has been used with 21049 samples including 19938 training and 1111 testing *** proposed model consists of mean and median filtering as pre-processing techniques applied to the database for enhancing the accuracy by mitigating the impact of environmental dispersion and investigated machine learning algorithms(kNN,WkNN,FSkNN,and SVM)for estimating the *** proposed SVM with median filtering algorithm gives a reduced mean positioning error of 0.7959 m and an improved efficiency of 92.84%as compared to all variants of the proposed method for 108703 m^(2) area.

关键词： Indoor positioning system fingerprinting received signal strength indicator mean position error support vector machine

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