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A New Discovery of Mineralization as Subseafloor Hydrothermal Replacement in the Duddar Super-Large SEDEX Lead-Zinc Deposit in Pakistan

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Journal of Earth Science 2024年第3期35卷 1075-1078页

作者： Huishan Zhang Yucai Song Jianing Sun Jun Hong yasir Shaheen Khalil Yanguang Li Haidi Zhang Zhihua Wang MNR Key Laboratory for the Study of Focused Magmatism and Giant Ore Deposits Xi’an Center of Geological SurveyChina Geological SurveyXi’an 710054China Institute of Geology Chinese Academy of Geological SciencesBeijing 100037China Chengdu Center of Geological Survey China Geological SurveyChengdu 610081China China Huaye Group Co. LtdBeijing 100037China Geological Survey of Pakistan Islamabad 44000Pakistan

0 INTRODUCTION Sedimentary exhalative(SEDEX)lead-zinc deposit was traditionally considered as a result of submarine hydrothermal exhalation,including exhalative plume and brine pool models(Izanloo et al.,2022;Spinks et al.,2021;Maghfouri et al.,2020;Sangster,2020,2018;Huang et al.,2019;Rajabi et al.,2015;Goodfellow and Lydon,2007;Large et al.,2005,2001;Peng et al.,2000;Goodfellow et al.,1993;Figures 1a,1b).However,recognition of mineralization as subseafloor hydrothermal replacement in a few SEDEX deposits has challenged the traditional consideration(Magnall et al.,2023,2021,2020a,b;Hayward et al.,2021;Figure 1c).Researchers come to believe that subseafloor replacement rather than submarine exhalation is a dominant process for SEDEX mineralization,but this needs to be examined through more case studies.

关键词： submarine mineralization seafloor

Trends in upper gastrointestinal bleeding management

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World Journal of Clinical Cases 2024年第27期12卷 6007-6010页

作者： yasir M Khayyat Department of Medicine Faculty of MedicineUmm AL-Qura UniversityMakkah 8156-24381Saudi Arabia

Upper gastrointestinal bleeding(UGIB)can be attributed to either non-variceal or variceal *** latter is more aggressive with hemodynamic instability secondary to decompensated cirrhosis and portal ***-variceal UGIB(NVUGIB)occurs due to impaired gastroprotective mechanisms attributed to several drugs such as anticoagulants and nonsteroidal anti-inflammatory *** pylori infection contributes to the development of peptic ulcer bleeding as *** presentation can be either hemodynamically stable or *** the initial assessment a scoring system including patient-related factors(current cardiac,renal,and liver diseases and hemodynamic and labo-ratory parameters)is used to determine the patient’s *** Glasgow Blatchford score has been shown to be the most useful and *** with high-risk NVUGIB require urgent assessment and upper endoscopy to achieve better short-term and long-term outcomes such as less hospitalization,blood transfusion,and surgery.

关键词： Gastric Peptic Non-steroidal anti-inflammatory drugs Anticoagulants Melena

The association between mycotic pneumonia and neonatal septicemia

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Journal of Biosafety and Biosecurity 2024年第3期6卷 137-141页

作者： Salman Khalid Salman yasir Mufeed Abdulateef Sawsan Qahtan Taha Al-Quhli Department of Microbiology College of MedicineUniversity of AnbarIraq

Background:Candida species are the fourth most common etiological agents of late-onset infection in the neonatal intensive care unit(NICU)and are responsible for considerable morbidity and ***:From November 2023 to February 2024,we investigated the association of mycotic pneumonia with septicemia in 60 neonates,and their roles of mycotic pneumonia in the morbidity and mortality of neonates in two NICUs in the Al-Ramadi Teaching Hospital for Maternity and ***:All infants in this study had been diagnosed with septicemia and treated with empirical antimicrobial *** early morning nasogastric tube(NG-tube)was used to collect swallowed sputum by suction for culture and sensitivity ***:The average white blood count for the neonates was 8547±5884.5 cells/mm^(2).The mean C-reactive protein was 39.3±26 mg/l,the mean serum albumin was 2.9±0.2 g/dl and the positive bacterial blood culture was 28(46.7%).9(15%)neonates died during the study *** NG-tube culture identified fungal growth in all *** these,49(81.6%)were identified as Candida albicans,6(10%)as Candida tropicalis,and 5(8.3%)as Cryptococcus *** bacterial culture results from the NG-tube samples identified 13(21.6%)patients with gram-positive bacteria and 47(78.3%)with gram-negative ***:We found a prevalence of Candida *** neonates in addition to microbial oxygen tube contamination,indicating a biosafety breach in the neonatal *** infection requires global attention as a probable cause of respiratory failure in neonatal septicemia.

关键词： Neonatal sepsis Mycotic pneumonia Anti-Mycotic therapy NG-tube culture Nosocomial infections

National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma

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World Journal of Gastroenterology 2024年第9期30卷 1018-1042页

作者： Faisal Saud Dar Zaigham Abbas Irfan Ahmed muhammad Atique Usman Iqbal Aujla muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider Syed Mujahid Hassan Adnan Abdul Jabbar Aman Nawaz Khan muhammad Shoaib Khan muhammad yasir Khan Amer Latif Nasir Hassan Luck Ahmad Karim Malik Kamran Rashid Sohail Rashid Mohammad Salih Abdullah Saeed Amjad Salamat Ghias-un-Nabi Tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed Department of Hepatopancreatic Biliary Surgery&Liver Transplant Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Hepatogastroenterology and Liver Transplantation Dr.Ziauddin University HospitalKarachi 75600SindhPakistan University of Aberdeen Aberdeen B243FXUnited Kingdom Department of Pathology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Gastroenterology&Hepatology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Radiology Aga Khan UniversityKarachi 74800Pakistan Department of Oncology Hameed Latif HospitalLahore 54000Pakistan Division of Hepatopancreatic Biliary Surgery&Liver Transplantation Shifa International HospitalIslamabad 44000Pakistan Department of Hepatopancreatic Biliary Surgery&Liver Transplant Shaikh Zayed Hospital and Post Graduate Medical InstituteLahore 54000Pakistan Department of Medicine Aga Khan University HospitalKarachi 74800Pakistan Department of Liver Transplant Pir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Medicine&Gastroenterology Lifecare Hospital and Research CentrePeshawar 25000Khyber PakhtunkhwaPakistan Department of Hepatopancreatobiliary&Liver Transplant Bahria International HospitalLahore 54000Pakistan Department of Surgery Hepatopancreatobiliary&Liver TransplantDow University of Health SciencesKarachi 74800Pakistan Department of Gastroenterology Hepatology&NutritionPir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Oncology Dr.Ziauddin HospitalKarachi 74800Pakistan Department of Radiology Rehman Medical InstitutePeshawar 25000Pakistan Army Liver Transplant Unit Pak Emirates Military HospitalRawalpindi 46000Pakistan Department of Gastroenterology Sindh Institute of Urology and TransplantationKarachi 75500Pakistan Rashid Nursing Home and Cancer Clinic Rashid Nursing Home and Cancer ClinicRawalpindi 46000Pakistan Department of Gastroentero

A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the *** Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this *** effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these *** coordinated effort can minimise delays and give patients a chance for curative treatment and effective *** diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance *** cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for ***,histopathologic confirmation is not always required before *** ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for *** only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette *** patients with unresectable hCCA can be considered for liver *** chemotherapy should be offered to patients with a high risk of *** use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary *** with acute cholangitis can be drained with endoscopic or percutaneous biliary *** chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.

关键词： Hilar cholangiocarcinoma Bismuth-Corlette classification Memorial Sloan Kettering Cancer Centre Staging Preoperative biliary drainage Portal vein embolisation Surgical resection Hepatectomy

Comprehensive Analysis of Estrogen Receptor 1 Dysregulation in Liver Hepatocellular Carcinoma: Implications for Prognosis and Therapeutic Targeting - A Secondary Publication

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Proceedings of Anticancer Research 2024年第3期8卷 51-59页

作者： Syed Hussain Raza yasir Hameed Department of Biochemistry and Biotechnology The Islamia University of BahawalpurBahawalpurPakistan

The study investigates the expression pattern and regulatory mechanisms of estrogen receptor 1 (ESR1) in liver hepatocellular carcinoma (LIHC) through comprehensive bioinformatics analysis. Utilizing UALCAN and GEPIA2 databases, significant down-regulation of ESR1 expression is observed in LIHC samples compared to normal controls, indicating its potential role in tumor progression. Further analysis reveals consistent down-regulation across different clinical variables including patient age, gender, race, and various stages of LIHC, affirming the regulatory role of ESR1 in tumor development and progression. Additionally, promoter methylation analysis demonstrates hypermethylation of ESR1 in LIHC samples, negatively correlating with its expression. This association persists across different clinical parameters, emphasizing the inverse relationship between ESR1 methylation and expression levels. Survival analysis indicates that up- regulation of ESR1 is associated with better overall survival, suggesting its potential as a prognostic biomarker in LIHC. Furthermore, genetic mutation analysis using cBioPortal reveals a spectrum of alterations in ESR1, including amplification, missense mutation, deep deletion, splice mutation, and truncating mutation, highlighting the genetic complexity of ESR1 in LIHC. These findings collectively contribute to a deeper understanding of ESR1 dysregulation in LIHC and its clinical implications as a potential therapeutic target and prognostic marker.

关键词： Estrogen receptor 1 Liver hepatocellular carcinoma Biomarker Prognosis

反相乳液聚合法制备缔合型耐盐聚合物及其流变性能

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精细化工 2024年第1期41卷 195-205页

作者：刘雅梦赖小娟杨振福 yasir MFMukhtar 文新卢丽娟陕西科技大学化学与化工学院轻化工助剂化学与技术教育部重点实验室陕西西安710021 中国石油集团川庆钻探工程有限公司长庆石油工程监督公司陕西西安710021 苏丹科技大学工程学院苏丹喀土穆47500

以丙烯酰胺(AM)、2-丙烯酰胺-十二烷基磺酸钠(AMC_(12)S)、疏水单体29-(4-辛基苯氧基)-3,6,9,12,15,18,21,24,27-壬氧烷酮基甲基丙烯酸酯(GTE-10)为原料,通过反相乳液聚合法制备了一种缔合型耐盐聚合物p(AM/AMC_(12)S/GTE-10)。通过FTIR、~1HNMR、SEM、TEM及激光粒度分析仪对其结构和形貌进行了表征,并对其流变性能、触变性能和黏弹性进行了评价。结果表明,疏水单体GTE-10成功引入聚合物中,聚合完成后的乳液粒径分布集中且均一,盐(NaCl、CaCl_(2))的加入使p(AM/AMC_(12)S/GTE-10)分子聚集态更紧密,形成的空间网络结构更稳定。质量分数为0.7%的p(AM/AMC12S/GTE-10)聚合物水溶液在140℃时表现出较好的耐温性能;在120℃、170s^(–1)条件下剪切1 h,在质量浓度为20000 mg/L的NaCl和CaCl_(2)水溶液中分别配制质量分数0.7%的聚合物溶液,其表观黏度分别为64.8和54.1m Pa·s;聚合物具有较好的剪切恢复性能;盐水条件下储能模量大于损耗模量,金属离子与苯氧乙烯基发生络合反应,使分子间作用力增强,形成的空间结构更稳定且难被破坏,黏弹性更高。

关键词：反相乳液聚合耐盐流变性能黏弹性触变性油田化学品

弹力带抗阻训练对巴基斯坦大学生板球运动员投掷球速度的影响研究

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弹力带抗阻训练对巴基斯坦大学生板球运动员投掷球速度的影响研究

作者： IQBAL yasir(尹贺) 首都体育学院

学位级别：硕士

带混合连接的装配式混凝土剪力墙抗震性能研究

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振动与冲击 2024年第19期43卷 306-318页

作者：韩启浩 yasir Naeem 汪大洋何建鑫江西理工大学土木与测绘工程学院江西赣州341000 广州大学土木工程学院广州510006

基于完成的带水平连接的装配式混凝土剪力墙(precast concrete shear walls with horizontal connection,PCSW-HC)试验研究,提出了一种带混合连接的装配式混凝土剪力墙(precast concrete shear walls with hybrid connection,PCSW-HVC),其中,水平连接采用高强螺栓的“强”连接方式,竖向连接采用钢剪切键(steel shear key,SSK)的“弱”连接方式。首先,结合已完成的试验,建立带水平连接的装配式混凝土剪力墙的数值模型,通过对比试验与数值分析结果,验证了材料本构关系的选取、各部件相互作用关系设置的正确性。进一步,采用同样的建模方法,建立带混合连接的装配式混凝土剪力墙的数值模型。分析了不同竖缝型式和增设钢剪切键对带混合连接的装配式混凝土剪力墙抗震性能的影响,揭示了其损伤失效模式。结果表明:单片剪力墙模块分割成较小尺寸模块拼装后,抗侧刚度有一定程度的减小,但刚度退化更缓慢,剪力墙墙板损伤更小,具有更好的变形能力;在剪力墙模块之间的竖缝中增设钢剪切键后,提高抗侧刚度的同时还可以改善其刚度退化行为,与不带钢剪切键模型相比,单片剪力墙(Single模型)和竖向滑动双片剪力墙(Sliding模型)峰值割线刚度分别提高了14.9%和11.4%;带混合连接的装配式混凝土剪力墙的损伤失效模式为“钢剪切键塑性屈服-墙板模块底部损伤-墙板模块破坏”,实现了钢剪切键塑性屈服耗能与墙板塑性损伤转移的“双功能”控制。

关键词：装配式混凝土剪力墙混合连接数值分析耗能失效模式

Parallel Technologies with Image Processing Using Inverse Filter

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Journal of Computer and Communications 2024年第1期12卷 110-119页

作者： Rahaf Alsharhan Areej Muheef Yasmin Al Ibrahim Afnan Rayyani yasir Alguwaifli College of Computer Science and Information Technology (CCSIT) Imam Abdulrahman Bin Faisal University (IAU) Dammam Saudi Arabia

Real-time capabilities and computational efficiency are provided by parallel image processing utilizing OpenMP. However, race conditions can affect the accuracy and reliability of the outcomes. This paper highlights the importance of addressing race conditions in parallel image processing, specifically focusing on color inverse filtering using OpenMP. We considered three solutions to solve race conditions, each with distinct characteristics: #pragma omp atomic: Protects individual memory operations for fine-grained control. #pragma omp critical: Protects entire code blocks for exclusive access. #pragma omp parallel sections reduction: Employs a reduction clause for safe aggregation of values across threads. Our findings show that the produced images were unaffected by race condition. However, it becomes evident that solving the race conditions in the code makes it significantly faster, especially when it is executed on multiple cores.

关键词： Parallel Parallelization Image Processing Inverse Filtering OpenMP Race Conditions