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Hepatitis C virus genotype 3a infection and hepatocellular carcinoma: Pakistan experience

World Journal of Gastroenterology 2009年第40期15卷 5080-5085页

作者： muhammad Idrees Shazia Rafi que Irshad-ur Rehman Haji Akbar muhammad zubair Yousaf Sadia Butt Zunaira Awan Sobia Manzoor Madiha Akram Mahwish Aftab Bushra Khubaib Sheikh Riazuddin Division of Molecular Virology & Molecular Diagnostics National Centre of Excellence in Molecular BiologyUniversity of the Punjab Lahore National Centre of Excellence in Molecular Biology University of the Punjab Lahore

AIM: To assess the association between chronic hepatitis C virus (HCV) infection and hepatocellular carcinoma (HCC) in Pakistan, and the genotype distribution among these HCC ***: One hundred and sixty-one subjects with HCC were included in this study. Liver biopsy was performed on 145 of the patients; sixteen were excluded because they failed to fulfill the inclusion criteria. Qualitative polymerase chain reaction (PCR) was performed for hepatitis B virus and HCV. Samples positive for HCV RNA were genotyped using genotype-specif ic PCR and conf irmed by HCV 5' noncoding region sequencing analysis. RESULTS: Chronic HCV infection was identified a major risk factor (63.44% of tested HCC patients) forthe development of HCC. The time from HCV infection to appearance of cancer was 10-50 years. In the HCC patient population, broader distributions of genotypes were present with genotype 3a as the predominant genotype. Using the type-specific genotyping method, we found HCV genotype 3a in 40.96%, 3b in 15.66%, 1a in 9.63%, and 1b in 2.40% of HCC tissue samples. About 28% of cases were found with mixed genotypes. Two cases were unable to be genotyped because of low viral load. Sixty-six percent of treated patients with cirrhosis had an end of treatment response, but unfortunately they relapsed quickly when the treatment was discontin-ued, and HCC developed during a median 3.8 years. CONCLUSION: There was a strong association between chronic HCV infection and HCC in Pakistan, and between HCV genotype 3a and HCC.

关键词： Hepatocellular carcinoma Hepatitis C Genotyping Etiology Prevalence

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Stochastic Programming for Hub Energy Management Considering Uncertainty Using Two-Point Estimate Method and Optimization Algorithm

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Computer Modeling in Engineering & Sciences 2023年第12期137卷 2163-2192页

作者： Ali S.Alghamdi Mohana Alanazi Abdulaziz Alanazi Yazeed Qasaymeh muhammad zubair Ahmed Bilal Awan M.G.B.Ashiq Department of Electrical Engineering College of EngineeringMajmaah UniversityAl-Majmaah11952Saudi Arabia Department of Electrical Engineering College of EngineeringJouf UniversitySakaka72341Saudi Arabia Department of Electrical Engineering College of EngineeringNorthern Border UniversityAr’Ar73222Saudi Arabia Automation and Control Department College of Engineering TechnologyUniversity of Doha for Science and TechnologyDoha24449Qatar Department of Electrical and Computer Engineering College of Engineering and Information TechnologyAjman UniversityAjman20550United Arab Emirates Department of Physics College of ScienceImam Abdulrahman Bin Faisal UniversityDammam31441Saudi Arabia

To maximize energy profit with the participation of electricity,natural gas,and district heating networks in the day-ahead market,stochastic scheduling of energy hubs taking into account the uncertainty of photovoltaic and wind resources,has been carried *** has been done using a new meta-heuristic algorithm,improved artificial rabbits optimization(IARO).In this study,the uncertainty of solar and wind energy sources is modeled using Hang’s two-point estimating method(TPEM).The IARO algorithm is applied to calculate the best capacity of hub energy equipment,such as solar and wind renewable energy sources,combined heat and power(CHP)systems,steamboilers,energy storage,and electric cars in the *** standard ARO algorithmis developed to mimic the foraging behavior of rabbits,and in this work,the algorithm’s effectiveness in avoiding premature convergence is improved by using the dystudynamic inertia weight *** proposed IARO-based scheduling framework’s performance is evaluated against that of traditional ARO,particle swarm optimization(PSO),and salp swarm algorithm(SSA).The findings show that,in comparison to previous approaches,the suggested meta-heuristic scheduling framework based on the IARO has increased energy profit in day-ahead electricity,gas,and heating markets by satisfying the operational and energy hub ***,the results show that TPEM approach dependability consideration decreased hub energy’s profit by 8.995%as compared to deterministic planning.

关键词： Stochastic energy hub scheduling energy profit uncertainty Hong’s two-point estimate method improved artificial rabbits optimization

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MEH-PPV/Alq_3-based bulk heterojunction photodetector

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Chinese Physics B 2013年第10期22卷 192-196页

作者： zubair Ahmad Mahdi Hasan Suhail Issam Ibrahim muhammad Wissam Khayer Al-Rawi Khaulah Sulaiman Qayyum Zafar Ahmad Sazali Hamzah Zurina Shaameri Low Dimensional Materials Research Center Department of PhysicsFaculty of ScienceUniversity of Malaya50603 Kuala LumpurMalaysia Department of Physics College of ScienceUniversity of BaghdadIraq Department of Physics College of ScienceUniversity of AnbarIraq Organic Synthesis Laboratory Institute of ScienceUniversiti Teknologi MARA40450 Shah AlamMalaysia

In this paper, we present the effect of varied illumination levels on the electrical properties of the organic blend bulk heterojuction （BHJ） photodiode. To prepare the BHJ blend, poly（2-methoxy-5（2P-ethylhexyloxy） phenyleneviny- lene （MEH-PPV） and aluminum-tris-（8-hydroxyquinoline）（Alq3） are used as donor and acceptor materials, respectively. In order to fabricate the photodiode, a 40-nm thick film of poly（3, 4-ethylendioxytbiophene）：poly（styrensulfonate）（PE- DOT：PSS） is primarily deposited on a cleaned ITO coated glass substrate by spin coating technique. The organic photo- sensitive blend is later spun coated on the PEDOT：PSS layer, followed by the lithium fluoride （LiF） and aluminium （A1） thin films deposition by thermal evaporation. The optical properties of the MEH-PPV：Alq3 blend thin films are investigated using photoluminescence （PL） and UV-Vis spectroscopy. The photodiode shows good photo-current response as a function of variable illumination levels. The responsivity value - 8 mA/W at 3 V is found and the ratio of photo-current to dark current （lph/IDark） is found to be 1.24.

关键词： MEH-PPV Alq3 bulk heterojunction photodiode

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Sero-Epidemiological Survey of Crimean-Congo Hemorrhagic Fever among the Human Population of the Punjab Province in Pakistan

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Virologica Sinica 2020年第4期35卷 486-489页

作者： muhammad Furqan Shahid muhammad zubair Shabbir Kamran Ashraf Muzaffar Ali Saima Yaqub Aziz Ul-Rahman Nageen Sardar Nadia Mukhtar Zarfishan Tahir Tahir Yaqub Department of Microbiology University of Veterinary and Animal SciencesLahore 54600Pakistan Quality Operation Laboratory University of Veterinary and Animal SciencesLahore 54600Pakistan Department of Parasitology University of Veterinary and Animal SciencesLahore 54600Pakistan Institute of Public Health Lahore 54600Pakistan

Dear Editor,Crimean-Congo hemorrhagic fever(CCHF),caused by the CCHF virus(CCHFV),is a tick-borne zoonotic infection characterized by myalgia,high-grade fever(>38℃),headache,nausea,bleeding from the body cavities,and in 10%–50%of cases,results in death(Swanepoel et al.1989).As CCHFV belongs to the Nairoviridae family,the virus can be transmitted to humans through the bite of infected ticks or by contact with the tissues or blood of infected animals(Bente et al.2013).

关键词： Population belongs Human

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The Laplacian Energy of Hesitancy Fuzzy Graphs in Decision-Making Problems

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Computer Systems Science & Engineering 2023年第3期44卷 2637-2653页

作者： N.Rajagopal Reddy Mohammad zubair khan S.Sharief Basha Abdulrahman Alahmadi Ahmed H.Alahmadi Chiranji Lal Chowdhary School of Advanced Sciences Vellore Institute of TechnologyVellore632014TamilnaduIndia Department of Computer Science and Information Taibah UniversityMedinaSaudi Arabia Department of Mathematics School of Advanced SciencesVellore Institute of TechnologyVellore632014TamilnaduIndia School of Information Technology and Engineering Vellore Institute of TechnologyVellore632014TamilnaduIndia

Decision-making(DM)is a process in which several persons concur-rently engage,examine the problems,evaluate potential alternatives,and select an appropriate option to the *** for determining order preference by similarity to the ideal solution(TOPSIS)is an established DM *** objective of this report happens to broaden the approach of TOPSIS to solve the DM issues designed with Hesitancy fuzzy data,in which evaluation evidence given by the experts on possible solutions is presents as Hesitancy fuzzy decision matrices,each of which is defined by Hesitancy fuzzy ***:we represent analytical results,such as designing a satellite communication network and assessing reservoir operation methods,to demonstrate that our suggested thoughts may be used in ***:We studied a new testing method for the arti-ficial communication system to give proof of the future construction of satellite earth *** aim to identify the best one from the different testing *** are alsofinding the best operation schemes in the *** this article,we present the concepts of Laplacian energy(LE)in Hesitancy fuzzy graphs(HFGs),the weight function of LE of HFGs,and the TOPSIS method technique is used to produce the hesitancy fuzzy weighted-average(HFWA).Also,consider practical examples to illustrate the applicability of thefinest design of satellite communication systems and also evaluation of reservoir schemes.

关键词： Hesitancy fuzzy graphs(HFGs) laplacian energy satellite communication system reservoir operation schemes decision-making

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Prevalence and interrelationships of foot ulcer, risk-factors and antibiotic resistance in foot ulcers in diabetic populations: A systematic review and meta-analysis

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World Journal of Diabetes 2020年第3期11卷 78-89页

作者： Mohammad zubair Department of Medical Microbiology Faculty of Medicine University of Tabuk

BACKGROUND Diabetic foot ulceration(DFU)is the prime health concern *** accounts for the major burden related to disease mortality and morbidity and economic *** timely and early recognition of the DFU can help present its occurrence and improve clinical *** To evaluate interrelationships between foot ulcers,risk factors,and antibiotic resistance among diabetic patients having ulcers in their *** The databases such as PubMed,ERIC,Medline,and Google Scholar were extensively used for the extraction of *** selected studies were published within the time-period of *** studies were selected,which were found to be completely relevant to the current *** The prevalence of diabetic foot ulcers among the population was evaluated,and the associated risk factors with its ***,few studies also reported on the bacteria that are found to be most prevailing among diabetic patients.A narrative discussion was drawn through this analysis,which was used to highlight the specific area of research through selected studies,extraction of the significant information that matched with the topic of research,and analysis of problem through the findings of the selected *** results helped in assessing significant knowledge regarding the risk factors of diabetic foot ulcers and the role of antimicrobial resistant in its *** The gram-negative bacteria were found to be the most common reason for diabetic foot *** study only included 10 studies that are not sufficient to produce generalized results,and no information was reported on the tests required to analyze antimicrobial susceptibility that can guide clinicians to propose better and sound treatment *** is evident that most study results depicted that the most common risk factors were found to be hypertension and neuropathy.

关键词： Amputation Diabetes mellitus Drug resistance Foot ulcer Gram-negative bacteria

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Humidity sensitive organic field effect transistor

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Journal of Semiconductors 2010年第5期31卷 40-44页

作者： I.Murtaza Kh S.Karimov zubair Ahmad I.Qazi M.Mahroof-Tahir T.A.khan T.Amin Ghulam Ishaq khan Institute of Engineering Sciences and Technology TopiSwabiNWFP23640Pakistan Physical Technical Institute of Academy of Sciences Dushanbe 734025Tajikistan St.Cloud State University MN 56301-4498USA

This paper reports the experimental results for the humidity dependent properties of an organic field effect *** organic field effect transistor was fabricated on thoroughly cleaned glass substrate,in which the junction between the metal gate and the organic channel plays the role of gate *** films of organic semiconductor copper phthalocynanine（CuPc） and semitransparent Al were deposited in sequence by vacuum thermal evaporation on the glass substrate with preliminarily deposited Ag source and drain *** output and transfer characteristics of the fabricated device were *** effect of humidity on the drain current,drain current-drain voltage relationship, and threshold voltage was *** was observed that humidity has a strong effect on the characteristics of the organic field effect transistor.

关键词： organic field effect transistor CuPc metal-semiconductor Schottky junction humidity sensor

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Cellular automata-based approach for digital image scrambling

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International Journal of Intelligent Computing and Cybernetics 2018年第3期11卷 353-370页

作者： zubair Jeelani Fasel Qadir Department of Computer Science University of KashmirSrinagarIndia

Purpose–The purpose of this paper is to investigate two-dimensional outer totalistic cellular automata(2D-OTCA)rules other than the Game of Life rule for image *** paper presents a digital image scrambling(DIS)technique based on 2D-OTCA for improving the scrambling *** comparison of scrambling performance and computational effort of proposed technique with existing CA-based image scrambling techniques is also ***/methodology/approach–In this paper,a DIS technique based on 2D-OTCA with von Neumann neighborhood(NvN)is *** of three important cellular automata(CA)parameters on gray difference degree(GDD)is analyzed:first the OTCA rules,afterwards two different boundary conditions and finally the number of CA generations(k)are *** authors selected a random sample of gray-scale images from the Berkeley Segmentation Data set and Benchmark,BSDS300(***/Research/Projects/CS/vision/bsds/)for the ***,the CA is setup with a random initial configuration and the GDD is computed by testing all OTCA rules,one by one,for CA generations ranging from 1 to 10.A subset of these tested rules produces high GDD values and shows positive correlation with the k ***,this sample of rules is used with different boundary conditions and applied to the sample image data set to analyze the effect of these boundary conditions on ***,in order to compare the scrambling performance of the proposed technique with the existing CA-based image scrambling techniques,the authors use same initial CA configuration,number of CA generations,k紏10,periodic boundary conditions and the same test ***–The experimental results are evaluated and analyzed using GDD parameter and then compared with existing *** technique results in better GDD values with 2D-OTCA rule 171 when compared with existing *** CPU running time of the proposed algorithm is also considerably small as compa

关键词： Cellular automata Image processing Gray difference degree Image encryption Image scrambling

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Multi-objective vendor managed inventory system with interval type-2 fuzzy demand and order quantities

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International Journal of Intelligent Computing and Cybernetics 2021年第3期14卷 439-466页

作者： zubair Ashraf Mohammad Shahid South Asian University New DelhiIndiaand Aligarh Muslim University AligarhIndia

Purpose-The proposed IT2FMOVMI model intends to concurrently minimize total cost and warehouse space for the single vendor-retailer,multi-item and a consolidated vendor *** demand and order quantities with the deterministic and type-1 fuzzy numbers,we have also formulated the classic/crisp MOVMI model and type-1 fuzzy MOVMI(T1FMOVMI)*** suggested solution technique can solve both crisp MOVMIand *** finding the optimal ordered quantities and backorder levels,the Paretofronts are constructed to form the solution sets for the three ***/methodology/approach-A multi-objective vendor managed inventory(MOVMI)is the most recognized marketing and delivery technique for the service provider and the retail in the supply chain in Industry *** to the evolving market conditions,the characteristics of the individual product,the delivery period and the manufacturing costs,the demand rate and order quantity of the MOVMI device are highly *** such a scenario,a MOVMI system with a deterministic demand rate and order quantity cannot be designed to estimate the highly unforeseen cost of the *** paper introduces a novel interval type-2 fuzzy multi-objective vendor managed inventory(IT2FMOVMI)system,which uses interval type-2 fuzzy numbers(IT2FNs)to represent demand rate and order *** the model is an NP-hard,the well-known meta-heuristic algorithm named NSGA-II(Non-dominated sorted genetic algorithm-II)with EKM(Enhanced Karnink-Mendel)algorithm based solution method has been ***-The experimental simulations for the five test problems that demonstrated distinct conditions are considered from the real-datasets of SAPCO *** study concludes that T1FMOVMI and crisp MOVMI schemes are outclassed by IT2FMOVMI model,offering more accurate Pareto-Fronts and efficiency measurement ***/value-Using fuzzy sets theory,a significant amount of work has been already done in past

关键词： Multi-objective vendor managed inventory Interval type-2 fuzzy demand Interval type-2 fuzzy ordered quantity Industry 4.0 NSGA-II

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Modeling the COVID-19 Pandemic Dynamics in Iran and China

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Computers, Materials & Continua 2021年第5期67卷 2111-2122页

作者： Jin Zhao zubair Ahmad Zahra Almaspoor School of Finance Shanghai Lixin University of Accounting and FinanceShanghaiChina Department of Statistics Yazd UniversityYazdIran

The epidemic outbreak COVID-19 was rst detected in the Wuhan city of China and then spread *** is of great interest to the researchers for its high rate of infection spread and its signicant number of fatalities.A detailed scientic analysis of this phenomenon is yet to ***,it is of interest of governments and other responsible institutions to have the right facts and gures to take every possible necessary action such as an arrangement of the appropriate quarantine activities,estimation of the required number of places in hospitals,assessment of the level of personal protection,and calculating the rate of isolation of infected persons,among *** this article,we compare the COVID-19 pandemic dynamics between the two most affected Asian countries Iran and China's *** provide a convenient method of data comparison that can be helpful for both governmental and private organizations to arrange the appropriate quarantine ***,a statistical model is suggested to provide the best characterization of the COVID-19 daily deaths data of Iran and *** analyzing daily death events,we observed that the proposed model provides a better description of the COVID-19 events,and therefore,can be used as a good candidate model for predicting them.

关键词： Coronavirus COVID-19 pandemic China Iran mathematical modeling statistical met

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