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Left lateral decubitus sleeping position is associated with improved gastroesophageal reflux disease symptoms: A systematic review and meta-analysis

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World Journal of Clinical Cases 2023年第30期11卷 7329-7336页

作者： Daniel Martin Simadibrata Elvira Lesmana Bagus Ramasha Amangku muhammad prasetio wardoyo Marcellus Simadibrata Department of Internal Medicine Faculty of Medicine Universitas IndonesiaJakarta 10430Indonesia Nuffield Department of Population Health University of OxfordOxford OX37LFUnited Kingdom Division of Gastroenterology and Hepatology Mayo ClinicRochesterMN 55905United States Division of Gastroenterology Department of Internal MedicineFaculty of Medicine Universitas IndonesiaJakarta 10430Indonesia

BACKGROUND A limited number of studies have demonstrated that sleeping in the left lateral decubitus(LLD)decreases nocturnal reflux in patients with gastroesophageal reflux disease(GERD)compared to right lateral decubitus(RLD)and *** This systematic review summarizes the association between sleeping in the LLD position and nocturnal reflux in patients with *** Studies published up to July 17,2023,in MEDLINE,EMBASE,and CENTRAL were *** studies were randomized and nonrandomized studies assessing the effect of sleeping in LLD compared to RLD and supine in reducing nocturnal reflux in GERD *** include the acid exposure time(AET)(%time in pH<4),acid clearance time(ACT)(in sec/episode),number of reflux episodes,and improvement in N-GSSIQ *** Two nonrandomized studies showed decreased AET and ACT in LLD sleep position in comparison to RLD(mean difference[MD]-2.03[95%CI:-3.62 to-0.45];-81.84[95%CI:-127.48 to-36.20],respectively)and supine position(MD-2.71[95%CI:-4.34 to-1.09];-74.47[95%CI:-116.26 to-32.69],respectively).There was no difference in AET and ACT between RLD sleep position and ***,one randomized controlled trial investigating the use of electronic sleep positional therapy,which increased the duration of LLD sleep and decreased the duration of RLD sleep compared to sham,showed nocturnal symptoms improvement(improved N-GSSIQ score,increased reflux-free nights,and resolution of nocturnal reflux symptoms).CONCLUSION Current evidence suggests that sleeping on the left side could reduce nocturnal reflux and improve GERD-related quality of life,therefore warranting interventions that promote LLD sleep position.

关键词： Gastroesophageal reflux disease Left lateral decubitus Sleep position Systematic review

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Comparison of the morphology and structure of W03 nanomaterials synthesized by a sol-gel method followed by calcination^or hydrothermal treatment

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Frontiers of Chemical Science and Engineering 2012年第4期6卷 371-380页

作者： Diah Susanti Stefanus Haryo N Hasnan Nisfu Eko prasetio Nugroho Hariyati Purwaningsih GeorgeEndri Kusuma Shao-Ju Shih Materials and Metallurgical Engineering Department Faculty of Industrial Technology Sepuluh Nopember Institute of Technology (ITS) Surabaya 60111 Indonesia Mechanical Engineering Department Surabaya State Shipbuilding Polytechnic Surabaya 60111 Indonesia Materials Science and Engineering Department Taiwan Tech (NTUST) Taipei 106 China

Tungsten （VI） oxide （WO3） nanomaterials were synthesized by a sol-gel method using WC16 and C2HsOH as precursors followed by calcination or hydrothermal treatment. X-Ray diffraction （XRD）, scanning electron microscopy （SEM） and high resolution transmission electron microscopy （HRTEM） equipped with energy dispersive X-ray spectroscopy （EDX） were used to characterize the structure and morphology of the materials. There were significant differences between the WO3 materials that were calcinated and those that were subjected to a hydrothermal process. The XRD results revealed that calcination temperatures of 300℃and 400℃ gave hexagonal structures and temperatures of 500℃ and 600℃ gave monoclinic structures. The SEM images showed that an increase in calcination temperature led to a decrease in the WO3 powder particle size. The TEM analysis showed that several nanoparticles agglomerated to form bigger clusters. The hydrothermal process produced hexagonal structures for holding times of 12, 16, and 20 h and monoclinic structures for a holding time of 24 h. The SEM results showed transparent rectangular panicles which according to the TEM results originated from the aggregation of several nanotubes.

关键词： WO3 nanomaterial sol-gel method calcina-tion hydrothermal

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