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Biomedical and Environmental Sciences 2020年第11期33卷 882-886页

作者： Sania Naz muhammad majid muhammad Zia Department of Biotechnology Quaid-i-Azam University Islamabad Pakistan 45320 Department of Pharmacy Quaid-i-Azam University Islamabad Pakistan 45320

The exploitation of nanotechnology has increased in all ramifications due to the spectacular potential of nano-products(NPs).Among the nanoproducts,iron oxide(Fe2 O3)NPs has attracted more scientific attentions due it... 详细信息

关键词： characteristics. Iron Oxide

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Robust and Efficient Reliability Estimation for Exponential Distribution

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Computers, Materials & Continua 2021年第11期69卷 2807-2824页

作者： muhammad Aslam Mohd Safari Nurulkamal Masseran muhammad Hilmi Abdul majid Department of Mathematics Faculty of ScienceUniversiti Putra MalaysiaUPM Serdang43400SelangorMalaysia Department of Mathematical Sciences Faculty of Science and TechnologyUniversiti Kebangsaan MalaysiaUKM Bangi43600SelangorMalaysia

In modeling reliability data,the exponential distribution is commonly used due to its *** estimating the parameter of the exponential distribution,classical estimators including maximum likelihood estimator represent the most commonly used method and are well known to be ***,the maximum likelihood estimator is highly sensitive in the presence of contamination or *** this study,a robust and efficient estimator of the exponential distribution parameter was proposed based on the probability integral transform *** examine the robustness of this new estimator,asymptotic variance,breakdown point,and gross error sensitivity were *** new estimator offers reasonable protection against outliers besides being simple to ***,a simulation study was conducted to compare the performance of this new estimator with the maximum likelihood estimator,weighted likelihood estimator,and M-scale estimator in the presence of ***,a statistical analysis of three reliability data sets was conducted to demonstrate the performance of the proposed estimator.

关键词： Exponential distribution M-estimator probability integral transform statistic robust estimation reliability

Resource Management in UAV Enabled MEC Networks

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Computers, Materials & Continua 2023年第3期74卷 4847-4860页

作者： muhammad Abrar Ziyad M.Almohaimeed Ushna Ajmal Rizwan Akram Rooha Masroor muhammad majid Hussain Bahauddin Zakariya University Department of Electrical EngineeringMultan60000Pakistan Department of Electrical Engineering College of EngineeringQassim UniversityBuraidah51452Saudi Arabia COMSATS University WAH Campus Islamabad47040Pakistan Department of Electrical and Electronics Engineering University of South WalesPontypirddCF371DLUK

Mobile edge cloud networks can be used to offload computationally intensive tasks from Internet of Things(IoT)devices to nearby mobile edge servers,thereby lowering energy consumption and response time for ground mobile users or IoT *** of Unmanned Aerial Vehicles(UAVs)and the mobile edge computing(MEC)server will significantly benefit small,battery-powered,and energy-constrained devices in 5G and future wireless *** address the problem of maximising computation efficiency in U-MEC networks by optimising the user association and offloading indicator(OI),the computational capacity(CC),the power consumption,the time duration,and the optimal location planning *** is possible to assign some heavy tasks to the UAV for faster processing and small ones to the mobile users(MUs)*** paper utilizes the k-means clustering algorithm,the interior point method,and the conjugate gradient method to iteratively solve the non-convex multi-objective resource allocation *** to simulation results,both local and offloading schemes give optimal solution.

关键词： Mobile edge computing internet of things UAVs ground mobile users

Identification,Isolation and Characterization of GaCyPI Gene in Gossypium arboreum under Cotton Leaf Curl Virus Disease Stress

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Phyton-International Journal of Experimental Botany 2021年第6期90卷 1613-1632页

作者： Zunaira Sher muhammad Umair majid Sameera Hassan Fatima Batool Beenish Aftab Bushra Rashid Centre of Excellence in Molecular Biology University of the PunjabLahore53700Pakistan Department of Biological Sciences Faculty of Fisheries&Wild LifeUniversity of Veterinary and Animal Sciences-Ravi CampusPattoki55300Pakistan

Pakistan is facing the threat of Cotton Leaf Curl Virus(CLCuV)which is transmitted through whitefly to cotton *** mechanism of leaf epicuticular wax protects the plants from different pathogens including insect attack and disease *** of current study is the isolation and characterization of a wax related gene GaCyPI from Gossypium arboreum under CLCuV infection.A fragment of 475 bp was isolated from the total RNA and 3’and 5’RACE-PCR products were arranged by overlapping the extended sequences at both the *** protein sequence of GaCyPI showed homology with Cyclophilin cis-trans isomerase gene of Gossypium ramondii and Gossypium *** sequence alignment also revealed homology among the coding sequences of same *** protein comprised of 173 amino acids and ORF finder revealed the 69 bases upstream at 5’while 350 bp at 3’*** revealed that it belongs to Cyclophilin-type peptidyl prolyl cis/trans isomerase(PPIase)*** sites are visible at specific amino acid positions and 3D structure was stable in Ramachandran *** server showed protein residues have average 3D-1D score>=0.2 and Z-Score was−*** analysis revealed that *** is the closest species that shares the same ***,GaCyPI has strong role in plants’epicuticular wax and its genetic transformation may protect the cotton from whitefly which transmits CLCuV.

关键词： Cotton plant wax virus transmission cyclophilin gene family expressed sequence tag

Examining the Quality Metrics of a Communication Network with Distributed Software-Defined Networking Architecture

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Computer Modeling in Engineering & Sciences 2024年第11期141卷 1673-1708页

作者： Khawaja Tahir Mehmood Shahid Atiq Intisar Ali Sajjad muhammad majid Hussain Malik M.Abdul Basit Department of Electrical Engineering Khwaja Fareed University of Engineering and Information TechnologyRahim Yar Khan64200Pakistan Department of Telecommunication Systems Bahauddin Zakariya UniversityMultan60000Pakistan Department of Electrical Engineering University of Engineering and TechnologyTaxila47050Pakistan School of Engineering and Physical Sciences Heriot-Watt UniversityEdinburghEH144ASUK

Software-Defined Networking(SDN),with segregated data and control planes,provides faster data routing,stability,and enhanced quality metrics,such as throughput(Th),maximum available bandwidth(Bd(max)),data transfer(DTransfer),and reduction in end-to-end delay(D(E-E)).This paper explores the critical work of deploying SDN in large-scale Data Center Networks(DCNs)to enhance its Quality of Service(QoS)parameters,using logically distributed control *** is a noticeable increase in Delay(E-E)when adopting SDN with a unified(single)control structure in big DCNs to handle Hypertext Transfer Protocol(HTTP)requests causing a reduction in network quality parameters(Bd(max),Th,DTransfer,D(E-E),etc.).This article examines the network performance in terms of quality matrices(bandwidth,throughput,data transfer,etc.),by establishing a large-scale SDN-based virtual network in the Mininet *** SDN network is simulated in three stages:(1)An SDN network with unitary controller-POX to manage the data traffic flow of the network without the server load management algorithm.(2)An SDN network with only one controller to manage the data traffic flow of the network with a server load management algorithm.(3)Deployment of SDN in proposed control arrangement(logically distributed controlled framework)with multiple controllers managing data traffic flow under the proposed Intelligent Sensing Server Load Management(ISSLM)*** a result of this approach,the network quality parameters in large-scale networks are enhanced.

关键词： Software defined networking quality of service hypertext transfer protocol data transfer rate latency maximum available bandwidth server load management

A Review Study of Wireless Sensor Networks and Its Security

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Communications and Network 2015年第4期7卷 172-179页

作者： muhammad Umar Aftab Omair Ashraf muhammad Irfan muhammad majid Amna Nisar muhammad Asif Habib Department of Computer Science and Engineering Yuan Ze University Taiwan Department of Computer Science NFC-IEFR Faisalabad Pakistan Land Record Management and Information System Faisalabad Pakistan IT Department Post Graduate College Faisalabad Pakistan Department of Computer Science National Textile University Faisalabad Pakistan

The confluence of cheap wireless communication, sensing and computation has produced a new group of smart devices and by using thousands of these kind of devices in self-organizing networks has formed a new technology that is called wireless sensor networks (WSNs). WSNs use sensor nodes that placed in open areas or in public places and with a huge number that creates many problems for the researchers and network designer, for giving an appropriate design for the wireless network. The problems are security, routing of data and processing of large amount of data etc. This paper describes the types of WSNs and the possible solutions for tackling the listed problems and solution of many other problems. This paper will deliver the knowledge about the WSN and types with literature review so that a person can get more knowledge about this emerging field.

关键词： WSN Overview of WSN WSN with Types WSN Security RBAC

Long-term outcomes of titanium-nitride-oxide coated stents and drug-eluting stents in acute coronary syndrome:A systematic review and meta-analysis

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World Journal of Cardiology 2024年第5期16卷 293-305页

作者： muhammad Ahmed Ali Fahim Afia Salman Hira Anas Khan Syed muhammad Hasan Muskan FatimaBhojani Sarah Aslam Amna Zia Ul Haq Vishal Reddy Bejugam Beena Muntaha Nasir Wajiha Gul Abdul Moeed Abdelrahman S Abdalla muhammad majid muhammad Sohaib Asghar Md Al Hasibuzzaman Department of Internal Medicine Dow University of Health SciencesKarachi 74200Pakistan Department of Internal Medicine North Central Bronx HospitalBronxNY 10467United States Department of Urology Center for Academic MedicineStanford University School of MedicinePalo AltoCA 33872United States Department of Cardiovascular Imaging Cleveland ClinicClevelandOH 44195United States Division of Nephrology and Hypertension Mayo Clinic RochesterRochesterMN 55905United States Institute of Nutrition and Food Science University of DhakaDhaka 1000Bangladesh

BACKGROUND In severe cases of coronary artery disease,percutaneous coronary intervention provide promising *** stent used could be a drug-eluting stent(DES)or a titanium-nitride-oxide coated stent(TiNOS).AIM To compare the 5-year effectiveness and safety of the two stent *** The following systematic review and meta-analysis was conducted in accordance with the preferred reporting items for systematic reviews and meta-analysis guidelines,and PubMed/MEDLINE,Scopus,and Cochrane Central were searched from inception till August *** outcomes were major adverse cardiac events(MACE),cardiac death,myocardial infarction(MI),cardiac death or MI,and ischemia-driven total lesion revascularization(ID-TLR).RESULTS Four randomized controlled trials(RCT),which analyzed a sum total of 3045 patients with acute coronary syndrome(ACS)after a median follow-up time of 5 years were *** statistically insignificant,an increase in the ID-TLR was observed in patients receiving TiNOSs vs *** addition,MI,cardiac death and MI,and definite stent thrombosis(DST)were significantly decreased in the TiNOS *** analysis revealed no significant results with meta-regression presenting non-ST elevated MI(NSTEMI)as a statistically significant covariate in the outcome of *** TiNOS was found to be superior to DES in terms of MI,cardiac death or MI,and DST outcomes,however,the effect of the two stent types on ID-TLR and MACE was not significant.A greater number of studies are required to establish an accurate comparison of patient outcomes in TiNOS and DES.

关键词： Stents Drug-eluting Major adverse cardiac events All-cause death Meta-analysis

Vagus nerve stimulation in intracerebral hemorrhage:the need for further research

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Neural Regeneration Research 2025年第11期20卷 3213-3214页

作者： Sheharyar S.Baig Ali N.Ali Arshad majid Sheffield Institute for Translational Neuroscience Division of NeuroscienceThe University of SheffieldSheffieldUK

Vagus nerve stimulation(VNS)and stroke:Stroke is the second leading cause of death and the third leading cause of disability worldwide(Baig et al.,2023).There have been significant paradigm shifts in the management of acute ischemic stroke through mechanical *** chronic ischemic stroke,invasive VNS paired with rehabilitation is associated with a significant increase in upper limb motor recovery and is FDA-approved(Baig et al.,2023).There are no treatments of similar efficacy in acute intracerebral hemorrhage(ICH)where several promising trials,e.g.,TICH-2,STOP-AUST,and TRAIGE did not show improvements in functional outcomes(Puy et al.,2023).

关键词： stimulation acute

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Regression analysis of squeezing-induced hybrid nanofluid flow in Darcy-Forchheimer porous medium

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 193-208页

作者： K.muhammad M.SARFRAZ Department of Humanities and Sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of Mathematics Quaid-i-Azam University

This article presents a mathematical model addressing a scenario involving a hybrid nanofluid flow between two infinite parallel plates. One plate remains stationary, while the other moves downward at a squeezing velocity. The space between these plates contains a Darcy-Forchheimer porous medium. A mixture of water-based fluid with gold(Au) and silicon dioxide(Si O2) nanoparticles is formulated. In contrast to the conventional Fourier's heat flux equation, this study employs the Cattaneo-Christov heat flux equation. A uniform magnetic field is applied perpendicular to the flow direction, invoking magnetohydrodynamic(MHD) effects. Further, the model accounts for Joule heating, which is the heat generated when an electric current passes through the fluid. The problem is solved via NDSolve in MATHEMATICA. Numerical and statistical analyses are conducted to provide insights into the behavior of the nanomaterials between the parallel plates with respect to the flow, energy transport, and skin *** findings of this study have potential applications in enhancing cooling systems and optimizing thermal management strategies. It is observed that the squeezing motion generates additional pressure gradients within the fluid, which enhances the flow rate but reduces the frictional drag. Consequently, the fluid is pushed more vigorously between the plates, increasing the flow velocity. As the fluid experiences higher flow rates due to the increased squeezing effect, it spends less time in the region between the plates. The thermal relaxation, however, abruptly changes the temperature, leading to a decrease in the temperature fluctuations.

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Single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： muhammad Junaid Eun Jeong Lee Su Bin Lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. Current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

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