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Aetiology and risk factors of ischaemic cholangiopathy after liver transplantation

World Journal of Gastroenterology 2014年第20期20卷 6159-6169页

作者： Moustafa Mabrouk mourad Abdullah Algarni Christos Liossis Simon R Bramhall Liver Unit Queen Elizabeth Hospital Birmingham B15 2TH United Kingdom

Liver transplantation (LT) is the best treatment for end-stage hepatic failure, with an excellent survival rates over the last decade. Biliary complications after LT pose a major challenge especially with the increasing number of procured organs after circulatory death. Ischaemic cholangiopathy (IC) is a set of disorders characterized by multiple diffuse strictures affecting the graft biliary system in the absence of hepatic artery thrombosis or stenosis. It commonly presents with cholestasis and cholangitis resulting in higher readmission rates, longer length of stay, repeated therapeutic interventions, and eventually re-transplantation with consequent effects on the patient’s quality of life and increased health care costs. The pathogenesis of IC is unclear and exhibits a higher prevalence with prolonged ischaemia time, donation after circulatory death (DCD), rejection, and cytomegalovirus infection. The majority of IC occurs within 12 mo after LT. Prolonged warm ischaemic times predispose to a profound injury with a subsequently higher prevalence of IC. Biliary complications and IC rates are between 16% and 29% in DCD grafts compared to between 3% and 17% in donation after brain death (DBD) grafts. The majority of ischaemic biliary lesions occur within 30 d in DCD compared to 90 d in DBD grafts following transplantation. However, there are many other risk factors for IC that should be considered. The benefits of DCD in expanding the donor pool are hindered by the higher incidence of IC with increased rates of re-transplantation. Careful donor selection and procurement might help to optimize the utilization of DCD grafts.

关键词： Ischaemic cholangiopathy Biliary complications Orthotopic liver transplantation Donation after circulatory death Reperfusion injury Cold ischaemia time

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Efficiency and degradation products elucidation of the photodegradation of mefenpyrdiethyl in water interface using TiO_2 P-25 and Hombikat UV100

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Journal of Environmental Sciences 2012年第9期24卷 1686-1693页

作者： Amina Chnirheb mourad Harir Basem Kanawati Mohammed El Azzouzi Istvan Gebefgi Philippe Schmitt-Kopplin Department of BioGeoChemistry and Analytik German Research Center for Environmental HealthHelmholtz Center MunichIngoldstdter Landstraβe 1D-85764 NeuherbergGermany University Mohammed V-Agdal Faculty of SciencesAvenue Ibn BatoutaBP 1014 RabatMorocco. Lehrstuhl fr Chemische-Technische Analyse und Chemische Lebensmitteltechnologie Technische Universitt MuenchenWeihenstephaner Steig 2385354 Freising-WeihenstephanGermany

The photodegradation of mefenpyrdiethyl （MFD）, an herbicide safener, was investigated in aqueous suspensions by using Degussa P-25 and Hombikat UV100 titanium oxide under simulated sunlight irradiation. The effects of initial concentration of the herbicide, pH, catalysts and hydrogen peroxide doses as well as their combinations were studied and optimized. Accordingly, the kinetic parameters were determined and the effectiveness of the processes was assessed by calculating the rate constants. A pseudo first-order kinetics was observed. Under experimental conditions, the degradation rate constants were strongly influenced using P-25 and no noticeable effect was observed for Hombikat UV100. DFT calculations with B3LYP/6-311＋G（2d,p）//B3LYP/6-31＋G（d,p） level of theory were performed to check whether significant conformational changes occur when the charge state of the MFD substrate changes and whether these changes could play a role in the dependency of photodegradation rate constant on the studied pH. High resolution mass spectrometry （FT-ICR/MS） was implemented to identify the main degradation products.

关键词： photodegradation mefenpyrdiethyl P-25/Hombikat UV100 kinetic degradation products

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Physical modeling and visualization of soil liquefaction under high confining stress

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Earthquake Engineering and Engineering Vibration 2005年第1期4卷 47-57页

作者： Lenart González Tarek Abdoun mourad Zeghal Vivian Kallou Michael K.Sharp Dept.of Civil and Environmental Engineering Rensselaer Polytechnic Inst.(RPI)TroyNYUSA Mueser Rutledge Consulting Engineers 225 W 34th StreetNew YorkNYUSA US Army Engineer Research and Development Center VicksburgMSUSA

The mechanisms of seismically-induced liquefaction of granular soils underhigh confining stresses are still not fully *** of these mechanisms is generallybased on extrapolation of observed behavior at shallow *** centrifuge model tests wereconducted at RPI's experimental facility to investigate the effects of confining stresses on thedynamic response of a deep horizontal deposit of saturated *** was observed at highconfining stresses in each of the tests.A system identification procedure was used to estimate theassociated shear strain and stress time *** histories revealed a response marked byshear strength degradation and dilative *** recorded accelerations and pore pressures wereemployed to generate visual animations of the *** visualizations revealed a liquefactionfront traveling downward and leading to large shear strains and isolation of upper soil layers.

关键词： centrifuge modeling high confining stress liquefaction system identification visualization

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Composition and antimicrobial activity of Cistus munbyi essential oil: an endemic plant from Algeria

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Journal of Forestry Research 2017年第6期28卷 1127-1132页

作者： Fethi Benbelaid Abdelmounaim Khadir mourad Bendahou Mohamed Amine Abdoune Alain Muselli Jean Costa Laboratory of Applied Microbiology in Food Biomedical and Environment Aboubekr Belkad UniversityP.O. Box 119 13000 Tlemcen Algeria Department of Biology University of Oran 1 Ahmed Ben Bella Es Senia Oran Algeria Laboratory of Natural Products Chemistry University of Corsica UMR CNRS 6134 Campus Grimaldi BP 5220250 Corte France Department of Biology Faculty of Sciences of Nature LifeEarth and Universe Aboubekr Belkad UniversityP.O. Box 119 13000 Tlemcen Algeria

The chemical composition and antimicrobial potential of Cistus munbyi essential oil were studied for the first time. GC and GC–MS analysis revealed 48 compounds representing 96.98% of the oil. Terpinen-4-ol(23.75%), meta-Cymene(17.30%), and Sabinene(12.38%)were the major constituents. Antimicrobial activity was evaluated against nine pathogens using the disc diffusion and broth micro-dilution methods. Results show that *** essential oil possesses strong antimicrobial activity against all strains, regardless if Gram-positive or Gramnegative bacteria, or yeast, with MICs values not exceeding10(mg/ml). In addition to its efficacy, C. munbyi essential oil has an unusual antimicrobial potency which is attributed to its specific chemical composition. Thus, findings presented here suggest that endemic C. munbyi contains a very interesting essential oil that may be valuable in several areas.

关键词： Antimicrobial activity Chemical composition Cistus munbyi Essential oil

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Atorvastatin-induced severe gastric ulceration: A case report

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World Journal of Gastroenterology 2005年第20期11卷 3159-3160页

作者： Ihab I El-Hajj Fadi H mourad Nina S Shabb Kassem A Barada Department of Internal Medicine American University of Beirut Medical Center(AUBMC) Beirut Lebanon Department of Pathology AUBMC Beirut Lebanon

A 41-year-old man presented with severe gastric ulceration 3 mo after beginning treatment with atorvastatin 20 mg once daily for hypercholesterolemia. The patient was not taking any ulcerogenic drugs and had no evidence of Helicobacter pylori infection. Proton pump inhibitor therapy was initiated and atorvastatin was replaced by simvastatin with complete resolution of gastrointestinal symptoms. To our knowledge, this is the first report of atorvastatin-induced gastric ulceration,which should be looked for in patients who develop abdominal pain while on this drug.

关键词： Atorvastatin Drug toxicity Gastric ulceration

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对基于拼接干涉术的同步辐射镜测量技术的研究

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红外与激光工程 2020年第3期49卷 169-177页

作者：黄磊王添翼 mourad Idir 布鲁克海文国家实验室国家同步辐射光源-Ⅱ美国纽约州阿普顿11973

随着同步辐射光源和自由电子激光器相关技术的发展和光束质量的提升,对用于转递和聚焦光束能量的X光反射镜的指标要求也逐渐提高。为避免引入额外的波前误差,反射镜面形高度误差均方根值的要求已逼近至亚纳米量级。如此苛刻的面形要求对... 详细信息

随着同步辐射光源和自由电子激光器相关技术的发展和光束质量的提升,对用于转递和聚焦光束能量的X光反射镜的指标要求也逐渐提高。为避免引入额外的波前误差,反射镜面形高度误差均方根值的要求已逼近至亚纳米量级。如此苛刻的面形要求对X光反射镜的测量工作带来了极大的困难和挑战。除了在各国同步辐射光源得到广泛使用的长程轮廓仪等基于角度测量的轮廓扫描仪器之外,基于激光干涉仪的拼接干涉技术也发展为测量同步辐射镜的一种有效手段。文中主要介绍了近期笔者等为测量X光反射镜而开发的拼接干涉平台。利用这一测量平台,研究了在不同的拼接参数下的多种拼接模式。着重讲述了其中纯软件拼接模式的基本原理和实际测量。用实测结果与不同测量仪器和不同研究机构的结果进行比对,验证了拼接干涉测量用于检测同步辐射镜的有效性,并展示了此拼接平台的测量表现。根据所得的测量数据看来,使用纯软件拼接模式来测量X光平面反射镜时,测量重复性的均方差值可以达到0.1 nm左右;而测量X光双曲柱面镜时(曲率半径的变化范围为50~130 m),测量重复性的均方差值为0.2~0.3 nm。此结果基本满足平面和接近平面(曲率半径大于50 m)的同步辐射镜常规检测和为确定性加工提供面形反馈的需要。

关键词：高精度光学测量 X光反射镜测量同步辐射镜检测拼接干涉术

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Simulation of the Hygrothermal Behavior of a Building Envelope Based on Phase Change Materials and a Bio-Based Concrete

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Fluid Dynamics & Materials Processing 2022年第5期18卷 1483-1494页

作者： Dongxia Wu mourad Rahim Wendong Li Mohammed El Ganaoui Rachid Bennacer University of Lorraine LERMABIUT H Poincaréde LongwyLongwy54400France University of Paris-Saclay ENS Paris-SaclayCNRSLMTGif-sur-Yvette91190France

Phase Change Materials(PCMs)have high thermal inertia,and hemp concrete(HC),a bio-based concrete,has strong hygroscopic *** previous studies,PCM has been extensively combined with many materials,however,most of these studies focused on thermal properties while neglecting hygroscopic *** this study,the two materials have been combined into a building envelope and the related hygrothermal properties have been *** particular,numerical studies have been performed to investigate the temperature and relative humidity behavior inside the HC,and the effect of adding PCM on the hygrothermal behavior of the *** results show that there is a high coupling between temperature and relative humidity inside the HC,since the relative humidity changes on the second and third days are different,with values of 8%and 4%,***,the variation of relative humidity with temperature indicates the dominant influence of temperature on relative humidity *** the presence of PCM,the temperature variation inside the HC is damped due to the high thermal inertia of the PCM,which also leads to suppression of moisture evaporation and thus damping of relative humidity *** the second and third days,the temperature changes at the central position are reduced by 4.6%and 5.1%,compared to the quarter *** the relative humidity change,the reductions are 5.3%and 5.4%on the second and third days,***,PCM,with high thermal inertia,acts as a temperature damper and has the potential to increase the moisture buffering capacity inside the *** makes it possible for such a combined envelope to have both thermal and hygric inertia.

关键词： Phase change material(PCM) bio-based concrete passive building envelope heat and moisture transfer hygrothermal performance

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Experimental investigation of hygrothermal behavior of wooden-frame house under real climate conditions

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Energy and Built Environment 2023年第1期4卷 122-129页

作者： mourad Rahim Rabah Djedjig Dongxia Wu Rachid Bennacer Mohammed EL Ganaoui University of Lorraine LERMABIUT H Poincaréde Longwy168 Rue de LorraineCosnes et Romain54400 LongwyFrance University of Paris-Saclay ENS Paris-SaclayCNRSLMT91190 Gif-sur-YvetteFrance

This paper deals with the experimental investigation of hygrothermal behavior of wooden-frame building *** experiment was based on in-situ monitoring of a full size experimental monozone house built at the University of *** in temperature and relative humidity inside and outside the envelope were logged simultaneously with local meteorological *** showed the high coupling between temperature and relative humidity variations within the envelope *** overall hygrothermal response of the wall highlighted an interesting hygrothermal dynamic behavior of the envelope which may contribute to mitigate variations of relative humidity inside the ***,relative humidity evolves within a range of values that can lead to mold growth at a certain position which may alter wooden envelope life.

关键词： 3 hygrothermal behavior Heat and mass transfer Wood Bio-based building envelope

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Effect of Hole Configuration on Heat Transfer through a Hollow Block Subjected to Solar Flux

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Fluid Dynamics & Materials Processing 2022年第5期18卷 1339-1348页

作者： mourad Najjaoui Thami Ait-Taleb Abdelhalim Abdelbaki Zaki Zrikem Hassan Chaib Polydiscilinary Faculty of Ouarzazate Ibn Zohr UniversityOuarzazate638Morocco Faculty of Sciences Semlalia Cadi Ayyad UniversityMarrakesh2390Morocco

In this paper,some effort is provided to optimize the geometry of a concrete hollow brick(used in the construction of building roofs)in order to increase the related thermal resistance,thereby reducing energy *** analysis is conducted for three different configurations of the hollow concrete *** of conduction,natural convection and thermal radiation phenomena is ***,the flows are assumed to be laminar and two-dimensional for the whole range of parameters *** conservation equations are solved by a finite difference method based on the control volumes approach and the SIMPLE algorithm for velocity-pressure *** results show that the aspect ratio affects neither the nature of the fluid flow nor the number of convective ***,the extension of the circulation cells increases with this ***,the cavities with a large aspect ratio lead to significant reductions in the heat transfer through the hollow block,these reductions reaching approximately 14%.

关键词： Heat transfers coupled hollow block solar flux aspect ratio control volumes

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Predicting Students’Final Performance Using Artificial Neural Networks

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Big Data Mining and Analytics 2022年第4期5卷 294-301页

作者： Tarik Ahajjam Mohammed Moutaib Haidar Aissa mourad Azrour Yousef Farhaoui Mohammed Fattah Department of Computer Science Faculty of Sciences and TechniquesMoulay Ismail UniversityErrachidia 52000Morocco IMAGE Laboratory Moulay Ismail UniversityMeknes 50000Morocco

Artificial Intelligence(AI)is based on algorithms that allow machines to make decisions for *** technology enhances the users’experience in various *** studies have been conducted in the field of education to solve the problem of student orientation and performance using various Machine Learning(ML)*** main goal of this article is to predict Moroccan students’performance in the region of Guelmim Oued Noun using an intelligent system based on neural networks,one of the best data mining techniques that provided us with the best results.

关键词： data science Artificial Intelligence(AI) Machine Learning(ML) neural networks prediction recommendation high school data analysis

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