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Hybrid Physics and Data-driven Contingency Filtering for Security Operation of Micro Energy-water Nexus

CSEE Journal of Power and Energy Systems 2023年第5期9卷 1820-1831页

作者： mostafa goodarzi Qifeng Li the Department of Electrical and Computer Engineering University of Central FloridaOrlandoFL 32816 USA

This paper investigates a novel engineering problem,i.e.,security-constrained multi-period operation of micro energywater *** problem is computationally challenging because of its high nonlinearity,nonconvexity,and large *** propose a two-stage iterative algorithm employing a hybrid physics and data-driven contingency filtering(CF)method and convexification to solve *** convexified master problem is solved in the first stage by considering the base case operation and binding contingencies set(BCS).The second stage updates BCS using physics-based data-driven methods,which include dynamic and filtered data *** method is faster than existing CF methods because it relies on offline optimization problems and contains a limited number of online optimization *** validate effectiveness of the proposed method using two different case studies:the IEEE 13-bus power system with the EPANET 8-node water system and the IEEE 33-bus power system with the Otsfeld 13-node water system.

关键词： Contingency filtering micro energy-water nexus multi-period secure operation optimal power and water flow physics-guided data-driven

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Isoimperatorin alleviates acetic acid-induced colitis in rats

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Asian Pacific Journal of Tropical Biomedicine 2024年第4期14卷 147-153页

作者： Saied goodarzi Amir Hossein Abdolghaffari Behnaz Najafi mostafa Pirali Hamedani Saeed Tavakoli Mahshad Marvi Maryam Baeeri Narguess Yassa Abbas Hadjiakhoondi Mohammad Abdollahi Zahra Tofighi Medicinal Plants Research Center Faculty of PharmacyTehran University of Medical SciencesTehranIran Department of Toxicology and Pharmacology Faculty of PharmacyTehran Medical SciencesIslamic Azad UniversityTehranIran Department of Pharmacognosy Faculty of PharmacyTehran University of Medical SciencesTehranIran Medicinal Plants Research Center Institute of Medicinal PlantsACECRKarajIran International Campus School of Pharmacy Tehran University of Medical SciencesTehranIran Toxicology and Diseases group The Pharmaceutical Sciences Research CenterTehran University of Medical SciencesTehranIran Department of Toxicology and Pharmacology Faculty of PharmacyTehran University of Medical SciencesTehranIran

Objective:To investigate the effect of isoimperatorin on histopathological and biochemical changes in acetic acid-induced colitis ***:Colitis was induced by intracolonic administration of acetic acid solution(4%v/v)in *** were divided into six groups including the sham group,the negative control group,the dexamethasone-treated group,and the groups treated with isoimperatorin(0.1,1,and 10 mg/kg/d by gavage).The treatments were administered for three days and then colonic status was assessed by macroscopic,histopathological,and biochemical ***:Isoimperatorin significantly alleviated colonic damage in a dose-dependent manner and improved histological changes in rats with acetic acid-induced *** also significantly reduced myeloperoxidase,TNF-α,IL-1β,and malodialdehyde ***:Isoimperatorin alleviates acetic acid-induced colitis in rats and may be a potential therapeutic agent for the treatment of colitis.

关键词： Isoimperatorin Inflammatory bowel disease Acetic acid Colitis TNF-α IL-1β

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