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Idiopathic steno-occlusive disease with bilateral internal carotid artery occlusion:A Case Report

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World Journal of Clinical Cases 2023年第13期11卷 3076-3085页

作者： Sherifa ahmed Hamed Hosam abozaid Yousef Department of Neurology and Psychiatry Assiut UniversityFaculty of MedicineAssiut 71516AssiutEgypt Department of Radiology Assiut UniversityFaculty of MedicineAssiut 71516AssiutEgypt

BACKGROUND Moyamoya disease(MMD)is a rare cause of acute stroke and transient ischemic attacks in *** described clinical,diagnostic features and follow-ups of a young child with acute *** SUMMARY We report a 4-year-old girl with left hemiparesis after an acute ischemic *** history was also significant for repeated left or right focal motor seizures,generalized tonic-clonic convulsions and transient ischemic *** magnetic resonance imaging and computed tomography(CT)of the brain and magnetic resonance angiography,CT angiography and venography on the cerebral vessels revealed evidence of bilateral fronto-parietal ischemic infarctions,occlusion of the right and left internal carotid arteries started at its bifurcation and non-visualization of right and left anterior and middle cerebral *** was evidence of progression in angiography manifested as development of collaterals from the basal perforating vessels,increase in the extent of large intracranial arterial stenosis/occlusion and extensive collateral circulation with predominance from the posterior *** and neurological evaluation and comprehensive laboratory investigations excluded an obvious comorbid disease or risk factor for the child’s *** diagnosis of MMD was highly suggested as a cause of the child’s steno-occlusive *** was treated symptomatically with levetiracetam,an antiepileptic *** was prescribed for secondary *** clinical manifestations were improved during the three years of *** surgery was *** Up to our knowledge,this is the first report for MMD in a child in our *** clinical improvement and the stabilization of the child’s condition over the 3 years of follow-up could be attributed to the rapid and extensive recruitment of collaterals and absence of risk factors or *** surgery is highly recommended.

关键词： Steno-occlusive disease Moyamoya disease Internal carotid artery Collateral circulation Neovascularization Case report

Risk factors and prognosis of pediatric rhegmatogenous retinal detachment in Egypt:a university hospital based study

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International Journal of Ophthalmology(English edition) 2023年第12期16卷 2034-2040页

作者： Mohamed Gaber Eissa Mohamad Amr Salah Eddin Abdelhakim Tamer ahmed Macky Hassan Aly mortada Department of Ophthalmology Kasr Al Ainy HospitalFaculty of MedicineCairo UniversityCairo 11431Egypt

AIM:To study and compare the predisposing factors and clinical features of pediatric,adult,and elderly rhegmatogenous retinal detachment(RRD).METHODS:This is an observational analytic crosssectional study in which patients with RRD admitted for surgery during 6mo period were divided into 3 age groups:pediatric(60y).Patients’demographic data,clinical features,RRD predisposing factors/features including myopia(axial length≥26.5 mm),aphakia/pseudophakia,blunt trauma,peripheral retinal degenerations,history of RRD in the fellow eye,and surgical interventions/findings were recorded and ***:Totally 142 patients(142 eyes)were studied:26(18.31%)pediatrics,86(60.56%)adults,and 30(21.13%)*** patients had a significantly higher intraocular pressures and cataracts compared to the other 2 groups(P=0.04).The RRD extent was larger in pediatric group(mostly 4 quadrants)compared to adults and elderly(mostly 2 quadrants),but it was not statistically insignificant(P=0.242).There were not statistically significantly differences in proliferative vitreoretinopathy(PVR)rate,posterior vitreous detachment(PVD)rate,number,site,shape,and size of breaks in three *** three groups had macular detachment in all *** and peripheral retinal degenerations were found to be more significant in adults(P=0.049,P=0.035,respectively),while blunt trauma was higher but insignificant in pediatric eyes(P=0.052).Pars plana vitrectomy(PPV)with silicone oil as a tamponade was the most used surgery in all ***:There are no significant difference in PVR rate in pediatric eyes but a significant higher rate of total *** trauma is more frequent in pediatrics eyes while myopia and/or peripheral retinal degenerations are more frequent in older *** rate of PPV as a choice for surgery is similar among all age groups.

关键词： rhegmatogenous retinal detachment pediatric predisposing factors proliferative vitreoretinopathy peripheral retinal degenerations

Consensus statement on the epidemiology,diagnosis,prevention,and management of cow's milk protein allergy in the Middle East:a modified Delphi-based study

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World Journal of Pediatrics 2021年第6期17卷 576-589页

作者： Moustafa A.El-Hodhod mortada H.F.El-Shabrawi ahmed AIBadi ahmed Hussein AM Almehaidib Basil Nasrallah Ebtsam Mohammed AIBassam Hala El Feghali Hasan M.Isa Khaled Al Saraf Maroun Sokhn Mehdi Adeli Najwa Mohammed Mousa Al-Sawi Pierre Hage Suleiman Al-Hammadi Department of Pediatrics Faculty of MedicineAin Shams UniversityCairoEgypt Faculty of Medicine October 6 UniversityGizaEgypt Faculty of Medicine Cairo UniversityCairoEgypt International Pediatric Association(IPA) MarengoUSA International Society of Tropical Pediatrics(ISTP) ManilaPhilippines DRC Hospital MuscatOman Al Amiri and Al Adan Hospitals KuwaitKuwait Pediatric Gastroenterology Department of PediatricsKing Faisal Specialist Hospital and Research Center RiyadhRiyadhSaudi Arabia American Hospital Dubai DubaiUnited Arab Emirates Nutrition Service Department King Faisal Specialist and Research Center RiyadhRiyadhSaudi Arabia CHU Notre Dame de Secours ByblosLebanon Pediatric Department Salmaniya Medical ComplexManamaBahrain Pediatric department Arabian Gulf UniversityManamaBahrain Pediatrics Department Dar Al Shifa HospitalKuwaitKuwait Pediatric Gastroenterology Hepatologyand Nutrition DepartmentSaint George University Medical CenterUniversity of BalamandBeirutLebanon Sidra Medicine DohaQatar Department of Pediatrics Doctor Sulaiman Alhabib Medical GroupAlrryan BranchRiyadhSaudi Arabia Pediatric Pulmonology and Allergology University of BalamandBeirutLebanon College of Medicine Mohanuned Bin Rashid University of Medicine and Health SciencesBuilding 14505055 DubaiUnited Arab Emirates

Background This study aimed to develop an expert consensus regarding the epidemiology,diagnosis,and management of cow’s milk protein allergy(CMPA)in the Middle *** A three-step modified Delphi method was utilized to develop the *** specialized pediatricians participated in the development of this *** statement was considered a consensus if it achieved an agreement level of>80%.Results The experts agreed that the double-blind placebo-controlled oral challenge test(OCT)should be performed for 2-A weeks using an amino acid formula(AAF)in formula-fed infants or children with suspected ***-fed infants with confirmed CMPA should be offered a therapeutic *** panel stated that an extensively hydrolyzed formula(eHF)is indicated in the absence of red flag *** the same time,the AAF is offered for infants with red flag signs,such as severe anaphylactic *** panel agreed that infants on an eHF with resolved symptoms within 2-4 weeks should continue the eHF with particular attention to the growth and nutritional *** the other hand,an AAF should be considered for infants with persistent symptoms;the AAF should be continued if the symptoms resolve within 2-4 weeks,with particular attention to the growth and nutritional *** cases with no symptomatic improvements after the introduction of an *** measures should be *** panel developed a management algorithm,which achieved an agreement level of 90.9%.Conclusion This consensus document combined the best available evidence and clinical experience to optimize the management of CMPA in the Middle East.

关键词： Consensus Cow's milk protein allergy Infant formula Middle East Milk hypersensitivity

A New Thioamide Derivative for Separation and Preconcentration of Multi Elements in Aquatic Environment by Cloud Point Extraction

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American Journal of Analytical Chemistry 2011年第6期2卷 697-709页

作者： Mohamed M. Hassanien Ali M. Hassan Wael I. mortada ahmed A. El-Asmy 不详

2-(pyridine-2-yl)-N-p-chlorohydrazinecarbothioamide (HCPTS) was synthesized, characterized and successfully applied for the preconcentration of Cu(II), Ni(II), Zn(II), Cd(II), Co(II), Pb(II), Fe(II), and Hg(II) in water, blood, and urine samples prior to graphite furnace atomic absorption determination (GFAAS);Hg was determined by cold vapor technique. Under the optimum experimental conditions (i.e. pH = 8, 10–4 M of HCPTS, 0.05% w/v of Triton X-114), calibration graphs were linear in the range of 0.02 to 200 ng?mL–1 for Co(II), Cd(II), Pb(II) and Ni(II);0.03 to 200 ng?mL–1 for Cu(II);0.07 to 200 ng?mL–1 for Fe(II) and Zn(II) and 0.02 to 150 ng?mL–1 for Hg(II). The enrichment factors were 43, 51, 41, 46, 54, 40, 45 and 52 for Cu(II), Ni(II),Zn (II), Cd(II), Co(II), Pb(II), Fe(II), and Hg(II), respectively. The limit of detection were found to be 0.019, 0.094, 0.0514, 0.052, 0.0165, 0.047, 0.068 and 0.041 ng?mL–1 for Cu(II), Ni(II), Zn(II), Cd(II), Co(II), Pb(II), Fe(II), and Hg(II), respectively. The developed method was applied to the determination of these metal ions in water, blood and urine samples with satisfactory results.

关键词： Heavy Metals Preconcentration Cloud Point Extraction 2-(Pyridine-2-Yl)-N-P-Chlorohydrazinecarbothioamide

Microwave Assisted Liberation of High Phosphorus Oolitic Iron Ore

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Journal of Minerals and Materials Characterization and Engineering 2014年第5期2卷 414-427页

作者： Mamdouh Omran Timo Fabritius Nagui Abdel-Khalek mortada El-Aref Abd El-Hamid Elmanawi Mahmoud Nasr ahmed Elmahdy Laboratory of Process Metallurgy Research Group Process and Environmental Engineering Department University of Oulu Oulu Finland Central Metallurgical Research and Development Institute Cairo Egypt Geology Department Faculty of Science Cairo University Cairo Egypt

The influence of microwave treatment on the liberation of iron ore from the high phosphorus oolitic iron ore from Aswan region, Egypt was studied. The effect of microwave power, exposure time and grain size on the liberation of iron ore was investigated. The microfractures and cracks of the samples were characterized before and after microwave treatments. The heating rate of high phosphorus oolitic iron ore was studied. Crystallinity of hematite was characterized before and after microwave pretreatment. The results indicated that intergranular fractures formed between the gangues (fluorapatite and chamosite) and hematite after microwave treatment, leading to improved liberation of iron ore and a significant reduction in comminution energy. Percentages of fraction ≤ -0.125 mm increased from 46.6% to 59.76% with increased exposure time from 0 to 60 seconds. The heating rate of iron ore showed that microwave treatment was less efficient at smaller particle sizes for a fixed applied power density. Crystallinity of hematite increased with the microwave exposure time.

关键词： Microwave Treatment High Phosphorus Oolitic Iron Ore Liberation

Gynecological Side Effects of Tamoxifen among Sudanese Women, Khartoum, Sudan, 2020

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Advances in Breast Cancer Research 2023年第4期12卷 152-162页

作者： Mawahib ahmed Elawad Abu Elgasim Yousra Abdelmoniem Suleiman Lobaina abozaid Dlal Alser Hassan Mohmmed Soha Saad Aldin Mohamad Suliman Duaa Hamd Abdulatif Farh Department of Family and Community Medicine College of Medicine Qassim University Buraidah Saudi Arabia Medical Oncology Department Armed Forces Hospital-Southern Region Khamis Mushait Saudi Arabia Department of Pathology College of Medicine Qassim University Buraidah Saudi Arabia Khartoum State Ministry of Health Khartoum Sudan

Background: In Sudan, the common endocrine therapy tamoxifen is prescribed to HR-positive patients, which is associated with a variety of complications such as hot flashes, vaginal discharge, and vaginal dryness. Objective: This study aimed to determine the gynecological side effects of tamoxifen among Sudanese women who have been diagnosed with breast cancer in Khartoum, Sudan. Methods: A retrospective cross-sectional study was conducted at Alzara Hospital in Al Amal Toure Revere, Sudan. A convenience sample of individuals previously diagnosed with breast cancer attended refer clinic. From October 2020 to September 2021, all patients attending were checked for eligibility. Results: A total of 100 patients were enrolled in the study;60% of patients reported increased vaginal secretions after taking the drug, 28% reported normal vaginal secretions with no change, and 11% reported decreased secretions after taking the medication, while 22% developed vaginal bleeding, and 22% of the ultrasound results revealed endometrial masses among the study patients. Also, 54 percent of female patients experienced hot flashes after taking the medication, and 12% of women missed some doses of treatment. Conclusion: Tamoxifen results in several gynecological side effects in women with breast cancer. A high percentage of women in the study developed hot flashes, vaginal bleeding, and discharge, in addition to having ultrasound results showing endometrial masses among them.

关键词： Tamoxifen Breast Cancer Gynecological Side Effects Sudanese Women