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Bone Mineral Density Reporting Underestimates Fracture Risk in Ontario

Health 2015年第5期7卷 566-571页

作者： Joanna E. M. Sale Earl Bogoch Lynn Meadows monique gignac Lucy Frankel Taucha Inrig Dorcas Beaton Ravi Jain Musculoskeletal Health and Outcomes Research Li Ka Shing Knowledge Institute St. Michael’s Hospital Toronto Canada Institute of Health Policy Management & Evaluation University of Toronto Toronto Canada Mobility Program St. Michael’s Hospital Toronto Canada Department of Surgery University of Toronto Toronto Canada Community Health Sciences University of Calgary Calgary Canada Toronto Western Research Institute University Health Network Toronto Canada Dalla Lana School of Public Health University of Toronto Toronto Canada Osteoporosis Canada Toronto Canada

Objective: Analysis of clinical documents such as bone mineral density (BMD) reports is an important component of program evaluation because it can provide insights into the accuracy of assessment of fracture risk communicated to patients and practitioners. Our objective was to compare fracture risk calculations from BMD test reports to those based on the 2010 Canadian guidelines. Methods: We retrieved BMD reports from fragility fracture patients screened through a community hospital fracture clinic participating in Ontario’s Fracture Clinic Screening Program. Fracture risk was determined according to the 2010 Canadian guidelines using age, sex, and T-score at the femoral neck, in addition to three clinical factors. Three researchers classified patients’ fracture risk until consensus was achieved. Results: We retrieved reports for 17 patients from nine different BMD clinics in the Greater Toronto Area. Each patient had a different primary care physician and all BMD tests were conducted after the 2010 Canadian guidelines were published. The fracture risk of 10 patients was misclassified with 9 of the 10 reports underestimating fracture risk. Nine reports acknowledged that the prevalence of a fragility fracture raised the risk category by one level but only four of these reports acknowledged that the patient had, or may have sustained, a fragility fracture. When we raised fracture risk by one level according to these reports, eight patients were still misclassified. Fracture risk in the majority of these patients remained underestimated. Inconsistent classification was found in the majority of cases where reports came from the same clinic. Four reports described risk levels for two different types of risk. Conclusions: More than half of patients received BMD reports which underestimated fracture risk. Bone health management recommendations based on falsely low fracture risk are likely to be sub-optimal.

关键词： Fracture Risk Bone Densitometry Reports Fragility Fracture Ontario

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布朗斯威克矿12号矿井的充填实践

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中国矿山工程 1981年第3期 37-43页

作者： Louis gignac 东宝林

布朗斯威克(Brunswick)矿山(12号矿井使用沿走向的分层充填法开采)每日生产矿石8400吨。因尾砂过细和含有很高的黄铁矿物,故选用了该矿6号露天坑的剥离廢石作为充填料。充填用的廢石先经破碎、运输、和通过错综复杂的充填井和鑽孔网路,... 详细信息

布朗斯威克(Brunswick)矿山(12号矿井使用沿走向的分层充填法开采)每日生产矿石8400吨。因尾砂过细和含有很高的黄铁矿物,故选用了该矿6号露天坑的剥离廢石作为充填料。充填用的廢石先经破碎、运输、和通过错综复杂的充填井和鑽孔网路,输送到充填工作面。即使一次充填高度较高,带有振动的无轨设备多次在充填面上行走,以及凿岩设备用水的渗透作用,其充填体的最终密实程度是一种中等的密度。当装矿操作时,建立严格的操作标准,以减少从廢石充填体中对矿石的贫化。最后对廢石充填与一般尾砂充填的强度、顶底盘的控制、贫化和经济等问题作了比较。

关键词：充填料矿石贫化尾砂矿井充填井威克朗斯

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母亲孕期海鲜摄入量和儿童注意力的关系:一项关于多不饱和脂肪酸相关基因效应修饰的队列研究

母亲孕期海鲜摄入量和儿童注意力的关系:一项关于多不饱和脂肪酸...

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作者： Julvez J Fernandez-Barres S gignac F Lopez-Vicente M Bustamante M Garcia-Esteban R Vioque J Llop S Ballester F Fernandez-Somoano A Tardon A Vrijheid M Tonne C Ibarluzea J Irazabal A Sebastian-Galles N Burgaleta M Romaguera D Sunyer J

背景:检验营养流行病学中胎儿编程的理论框架是非常有必要的。本实验在调整了儿童自身海鲜摄入量和认知功能等因素的基础上,调查评估了是否母亲孕期摄入海鲜和子代8岁时有更好的注意力有关。我们也探讨了几种与多不饱和脂肪酸代谢相关... 详细信息

背景:检验营养流行病学中胎儿编程的理论框架是非常有必要的。本实验在调整了儿童自身海鲜摄入量和认知功能等因素的基础上,调查评估了是否母亲孕期摄入海鲜和子代8岁时有更好的注意力有关。我们也探讨了几种与多不饱和脂肪酸代谢相关的单核苷酸多态性(Single Nucleotide Polymorphisms,SNPs)的效应修饰。

关键词：摄入量队列研究多不饱和脂肪酸基因效应

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Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli M.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot M. Ait Tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt M. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Aliev G. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. Alves Cardoso M.G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.T. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki T. Aoki J.A. Aparisi Pozo M.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli L.M. Baltes W.K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak M. Barakat E.L. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends T. Barillari M-S. Barisits T. Barklow P. Baron D.A. Baron Mo The ATLAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron Collider,as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGING

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