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Forecasting tropical cyclone coastal and marine hazards and impacts

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Tropical Cyclone Research and Review 2024年第1期13卷 1-14页

作者： Nadao Kohno Cody Fritz monica Sharma Robbie Berg Diana Greenslade Devon Telford Sakeasi Rabitu P.L.N.Murty M.Mohapatra Maria cristina C.Uson Japan Meteorological Agency TokyoJapan National Hurricane Center MiamiUSA India Meteorological Department New DelhiIndia Bureau of Meteorology MelbourneAustralia Environment and Climate Change Canada QuebecCanada Fiji Meteorological Service NadiFiji Philipine Atmospheric Geophysical and Astronomical Services AdministrationQuezon CityPhilippines

The report highlights the signiﬁcant progress over various regions with respect to understanding of coastal hazards,numerical modeling techniques and the generation&dissemination of coastal hazard warnings and *** developments over various regions in the globe during 2014–18 have been discussed in this report as presented during 10th Session of International Workshop on Tropical Cyclones(IWTC-X)at Bali,*** speciﬁcally,various regions have started to confront the uncertainty that cannot be removed from TC analyses and forecasts and further communicate those hazards within the context of risk[probabilistic]based *** also includes impact-based forecasts such as communicating coastal inundation information relative to total water level instead of storm surge,speciﬁcally(i.e.,anomaly from as-tronomical tide and waves).Lastly,updates to model grid conﬁguration,model resolution,and coupled dynamical systems continue to resolve the costal hazards more *** approaches have likely helped reduce loss of life relative to historical ***,regions agree that the generation and dissemination of coastal hazard information still need to be improved in view of growing population along the coast and thus increased exposure of life to coastal hazard.

关键词： Coastal inundation Storm surge Probabilistic forecast

Proline as a biochemical marker in relation to the ecology of two halophytic Juncus species

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Journal of Plant Ecology 2013年第2期6卷 177-186页

作者： monica Boscaiu cristina Lull Josep Llinares Oscar Vicente Herminio Boira Instituto Agroforestal Mediterráneo(IAM UPV)Universitat Politècnica de ValènciaCamino de Vera s/n46022 ValenciaSpain RE-FOREST Departamento de Ingeniería Hidráulica y Medio AmbienteUniversitat Politècnica de ValènciaCamino de Vera s/n46022 ValenciaSpain Instituto de Investigación para la Gestión Integral de Zonas Costeras(IGIC UPV)Universitat Politècnica de ValènciaCalle Paranimf 146730 Grau de GandíaValenciaSpain Instituto de Biología Molecular y Celular de Plantas(IBMCP UPV-CSIC)Universitat Politècnica de ValènciaCamino de Vera s/n46022 ValenciaSpain

Aims osmolytes,used for maintaining osmotic balance and as‘osmoprotectants’,are synthesized in plants as a general,con-served response to abiotic stress,although their contribution to stress-tolerance mechanisms remains ***,the most common osmolyte,accumulates in many plant species in parallel with increased external salinity and is considered a reliable bio-chemical marker of salt *** have measured proline levels in two halophytic,closely related Juncus species under laboratory and field conditions to assess the possible relevance of proline biosynthesis for salt tolerance and therefore for the ecology of these two *** Proline was quantified in plants treated with increasing NaCl con-centrations and in plants sampled in two salt marshes located in the provinces of Valencia and alicante,respectively,in southeast *** conductivity,pH,Na+and Cl−concentrations were measured in soil samples collected in parallel with the plant *** Findings Treatment with NaCl inhibited growth of *** plants in a concentration-dependent manner,but only under high salt conditions for *** treatments led to proline accumulation in both species,especially in the more salt-tolerant *** results,obtained under laboratory conditions,were confirmed in plants sam-pled in the *** all the samplings,proline contents were signifi-cantly lower in *** than in the more tolerant *** growing in the same *** direct correlation between soil salinity and proline levels could be established,but seasonal variations were detected,with increased proline contents under accentuated water deficit *** results suggest that proline biosynthesis is not only an induced,general response to salt stress but also an important contributing factor in the physiological mechanisms of salt tolerance in Juncus,and that it therefore correlates with the ecology of both species.

关键词： halophytes Juncus acutus Juncus maritimus osmolytes salt stress

Mindfulness interventions during pregnancy:A narrative review

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Journal of Integrative Medicine 2020年第6期18卷 470-477页

作者： Leandro Lucena cristina Frange Ana Claudia Amorim Pinto monica Levy Andersen Sergio Tufik Helena Hachul Department of Psychobiology Universidade Federal de Sao Paulo(UNIFESP)Sao Paulo 04023062Brazil Department of Neurology and Neurosurgery Universidade Federal de Sao Paulo(UNIFESP)Sao Paulo 04039002Brazil Department of Gynecology Universidade Federal de Sao Paulo(UNIFESP)Sao Paulo 04024002Brazil

Pregnancy is a period of major transformations in a woman’s life;increased stress,and mood and sleep disorders are *** review evaluates mindfulness interventions during pregnancy and their ability to help manage stress,anxiety,depression,emotional regulation,level of mindfulness and sleep quality.A search of English language scientific literature relevant to mindfulness interventions for pregnant women was conducted using PubMed,Scopus and Web of Science,without restriction on publication *** criteria were randomized clinical trials with pregnant women,using mindfulness as an intervention for at least three weeks,in one of our main areas of interest,and using only validated scales to measure *** hundred and thirty studies were identified in our searches of research databases,and thirteen were included in our *** found a large diversity of mindfulness programs,heterogeneity among the instruments used to evaluate outcomes,and inconsistency in the gestational periods used in the *** interventions were beneficial for stress,anxiety and *** was also effective when applied in pregnant women with a history of depression or experiencing *** emotional regulation and the level of mindfulness,there were signs of improvement,but more studies are *** of the studies evaluated sleep *** review provides information about current mindfulness programs,an overview of the effects of mindfulness interventions,a description of the measurements used so far,and recommendations for developing highquality mindfulness protocols for pregnant women.

关键词： Mindfulness Pregnancy Anxiety Stress Depression Sleep

Classification of osteogenesis imperfecta:Importance for prophylaxis and genetic counseling

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World Journal of Clinical Cases 2023年第12期11卷 2604-2620页

作者： monica-cristina Panzaru Andreea Florea Lavinia Caba Eusebiu Vlad Gorduza Department of Medical Genetics Faculty of Medicine“Grigore T.Popa”University of Medicine and PharmacyIasi 700115Romania Department of Medical Genetics-Medical Genetics resident “Grigore T.Popa”University of Medicine and PharmacyIasi 700115Romania

Osteogenesis imperfecta(OI)is a genetically heterogeneous monogenic disease characterized by decreased bone mass,bone fragility,and recurrent *** phenotypic spectrum varies considerably ranging from prenatal fractures with lethal outcomes to mild forms with few fractures and normal *** basic mechanism is a collagen-related defect,not only in synthesis but also in folding,processing,bone mineralization,or osteoblast *** recent years,great progress has been made in identifying new genes and molecular mechanisms underlying *** this context,the classification of OI has been revised several times and different types are *** Sillence classification,based on clinical and radiological characteristics,is currently used as a grading of clinical *** on the metabolic pathway,the functional classification allows identifying regulatory elements and targeting specific therapeutic *** classification has the advantage of identifying the inheritance pattern,an essential element for genetic counseling and *** genotype-phenotype correlations may sometimes be challenging,genetic diagnosis allows a personalized management strategy,accurate family planning,and pregnancy management decisions including options for mode of delivery,or early antenatal OI *** research on molecular pathways and pathogenic variants involved could lead to the development of genotype-based therapeutic *** narrative review summarizes our current understanding of genes,molecular mechanisms involved in OI,classifications,and their utility in prophylaxis.

关键词： Osteogenesis imperfecta Heterogeneity Classification Molecular mechanism Genetic counseling Prophylaxis

Effects of chlorpyrifos on enzymatic systems of Cydia pomonella （Lepidoptera： Tortricidae） adults

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Insect Science 2017年第3期24卷 455-466页

作者： Laura Beatriz Parra Morales Raul Adolfo Alzogaray Liliana Cichon Silvina Garrido Jimena Soleno cristina monica Montagna Laboratorio de Investigaciones Bioquimicas Quimicas y de Medio Ambiente Facultad de Ingenieria Universidad Nacional del ComahueBuenos Aires 1400 (Q83001BX) Neuquen Facultad de Ciencias del Ambiente y la Salud Universidad Nacional del Comahue Buenos Aires 1400 Neuquen Centro de Investigaciones de Plagas e Insecticidas (CIPEIN-UNIDEFICONICET) Villa Martelli Buenos Aires Instituto de Investigacion e Ingenieria Ambiental (3iA-UNSAM) San Martin Provincia de Buenos Aires Instituto Nacional de Tecnologia Agropecuaria Estacion Experimental Alto Valle General Roca Argentina

The control program of codling moth （Cydia pomonella L.） in the Rio Negro and Neuqu6n Valley is intended to neonate larvae. However, adults may be subjected to sublethal pesticide concentrations generating stress which might enhance both mutation rates and activity of the detoxification system. This study assessed the exposure effects of chlorpyrifos on target enzyme and, both detoxifying and antioxidant systems of surviving adults from both a laboratory susceptible strain （LSS） and a field population （FP）. The results showed that the FP was as susceptible to chlorpyrifos as the LSS and, both exhibited a similar chlorpyrifos-inhibitory concentration 50 （IC50） of acetylcholinesterase （ACHE）. The FP displayed higher carboxylesterase （CarE） and 7-ethoxycoumarine O-deethylase （ECOD） activities than LSS. Both LSS and FP showed an increase on CarE activity after the exposure to low-chlorpyrifos concentrations, followed by enzyme inhibition at higher concentrations. There were no significant differences neither in the activities of glutathione S-transferases （GST）, catalase （CAT） and superoxide dismutase （SOD） nor in the reduced glutathione （GSH） content between LSS and FP. Moreover, these enzymes were unaffected by chlorpyrifos. In conclusion, control adults from the FP exhibited higher CarE and ECOD activities than control adults from the LSS. AChE and CarE activities were the most affected by chlorpyrifos. Control strategies used for C. pomonella, such as rotations of insecticides with different modes of action, will probably delay the evolution of insecticide resistance in FPs from the study area.

关键词： acetylcholinesterase antioxidant system chlorpyrifos codling moth detoxification enzymes

Update on cardiomyopathies and sudden cardiac death

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Forensic Sciences Research 2019年第3期4卷 202-210页

作者： Stefania Rizzo Elisa Carturan monica De Gaspari Kalliopi Pilichou Gaetano Thiene cristina Basso Cardiovascular Pathology Department of Cardio-Thoracic-Vascular Sciences&Public Health and Azienda OspedalieraUniversity of Padua Medical SchoolPaduaItaly

Sudden cardiac death (SCD) remains a leading mode of death in western *** SCD can be the first and last clinical presentation of the underlying disease,autopsy could be the only medical examination available for early diagnosis and it should be performed according to the guidelines of the Association for European Cardiovascular *** the vast majority of SCD are due to coronary artery disease,non-ischemic causes of SCD do exist and are prevalent in young people with structural (***,hypertrophic and inflammatory cardiomyopathy) and non-structural (ion channel diseases)cardiomyopathies,accounting for up to one half of cases.A standardized autopsy protocol,in combination with blood sampling to ensure feasibility of postmortem molecular testing if needed,is *** pathologist is called to provide the correct diagnosis and to advice the relatives on the need of a cascade clinical and genetic screening in the presence of a heredo-familial disease.

关键词： Forensic sciences forensic pathology autopsy cardiomyopathies genetics sudden death

The neuroprotective effect of traditional Chinese medicinal plants--A critical review

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Acta Pharmaceutica Sinica B 2023年第8期13卷 3208-3237页

作者： Joao Moreira Mariana Machado monica Dias-Teixeira Ricardo Ferraz cristina Delerue-Matos Clara Grosso REQUIMTE/LAQV Instituto Superior de Engenharia do PortoInstituto Politecnico do PortoPorto 4249-015Portugal Ciencias Químicas e das Biomoleculas/CISA Escola Superior de SaudedInstituto Politecnico do PortoPorto 4200-072Portugal NICiTeS-Nucleo de Investigacao em Ciencias e Tecnologias da Saude Escola Superior de Saude Ribeiro SanchesLisboa 1950-396Portugal REQUIMTE/LAQV Departamento de Química e Bioquímica Faculdade de CienciasUniversidade do PortoPorto 4169-007Portugal

Neurodegenerative and neuropsychiatric diseases are increasingly affecting individuals’quality of life,thus increasing their cost to social and health *** diseases have overlapping mechanisms,such as oxidative stress,protein aggregation,neuroinflammation,neurotransmission impairment,mitochondrial dysfunction,and ***,there is no cure for neurodegenerative diseases,and the available therapies have adverse effects and low *** neuropsychiatric disorders,such as depression,the current therapies are not adequate to one-third of the patients,the so-called treatmentresistant ***,searching for new treatments is *** plants appear as a strong alternative and complement towards new treatment protocols,as they have been used for health purposes for thousands of ***,the main goal of this review is to revisit the neuroprotective potential of some of the most predominant medicinal plants(and one fungus)used in traditional Chinese medicine(TCM),focusing on their proven mechanisms of action and their chemical compositions,to give clues on how they can be useful against neurodegeneration progression.

关键词： Neurodegeneration Alzheimer's disease Parkinson's disease Depression Medicinal plants Oxidative stress Toxicology Clinicaltrials

Short-term effects of cleaning-respacing in a silver fir-dominated stand in Romania

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Journal of Forestry Research 2018年第6期29卷 1591-1599页

作者： Valeriu-Norocel Nicolescu Cornelia Hernea Diana-cristina Simon3 Matei-Nicolae Ciolan monica-Elena Barti Hendrik Schubert Edina Borbely Faculty of Silviculture and Forest Engineering Transylvania University of Brasov.irul Beethoven 1500123 BrasovRomania Faculty of Horticulture and Forestry Banat’s University of Agricultural Sciences and Veterinary Medicine“King Michael I of Romania”from Timi.oaraCalea Aradului 119300645 Timi.oaraRomania Barzava Forest District 317030 BarzavaAradRomania LIGNUM Forest District 605300 DarmanestiBacauRomania

This paper discusses the early silviculture of silver fir(Abies alba Mill.), a major softwood in Romania covering more than 294,000 ha. Three research plots(DRP1, DRP2 and DRP3) were established in a 25-year-old silver fir-dominated stand in May 2012. In DRP1 and DRP2, heavy cleaning-respacing were carried out while DRP3 was kept as a control. After the treatments in 2012,the plots had stocking between 1470 trees ha-1(DRP2) and10,030 trees ha-1(DRP3), basal areas between11.8 m2ha-1(DRP2) and 31.6 m2ha-1(DRP3). The average diameters were between 5.7 cm(DRP3) and 9.6 cm(DRP2). Measurements in September 2016 confirmed the rapid response of silver fir to *** best results in average diameter increments and basal area between 2012 and 2016 were in DRP2: 3.7 cm(36.4%) and 7.7 m2ha-1(85.0%) respectively. The largest diameter trees in 2012 were the best growers, and a strong linear correlation between the initial diameter of the remaining trees and their increment was established. Natural dieback of trees occurred only in DRP3(8.6%). The selection of crop trees based on the vigour, quality, and spacing criteria during cleaning-respacing was possible as individuals stood out in terms of vigour and early diameter growth. An issue encountered in DRP1 and DRP2 was the occurrence of epicormic shoots, especially on less vigorous individuals with small crowns. However, four years after cleaning-respacing, these branches are small and do not significantly affect the wood quality.

关键词： Abies alba Tending operations Stocking Basal area Increment

Transient immune hepatitis as post-coronavirus disease complication:A case report

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World Journal of Clinical Cases 2021年第16期9卷 4032-4039页

作者： Anca cristina Drăgănescu Oana Săndulescu Anuța Bilașco Camelia Kouris Anca Streinu-Cercel monica Luminos Adrian Streinu-Cercel Infectious Diseases Department National Institute for Infectious Diseases“Prof.Dr.Matei Balș”Bucharest 021105Romania Infectious Diseases Department Carol Davila University of Medicine and PharmacyBucharest 021105Romania

BACKGROUND We report a case of post-coronavirus disease(COVID)immune hepatitis occurring in a young male with no pre-existing *** SUMMARY A previously healthy 21-year-old male patient was admitted to our hospital with mild *** the course of in-hospital isolation and monitoring,he developed an alanine aminotransferase(ALT)and aspartate aminotransferase(AST)increase,with the enzymes peaking at day 24(ALT 15 times the upper normal limit),with preserved liver *** liver enzyme increase occurred 20 d after the complete clinical remission of COVID-19,and ALT dynamics paralleled the increase in total antibodies against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).The case was interpreted as post-COVID immune hepatitis,with extensive laboratory investigations excluding other potential *** hepatocytolysis remitted 20 d after the peak ALT,without further intervention,with complete recovery,but the total anti-SARS-CoV-2 antibodies continued to increase the next 5 mo following the acute *** Close attention should also be paid to young patients with mild forms of disease,and a high index of suspicion should be maintained for post-COVID complications.

关键词： COVID-19 Complications Liver Case report