检索结果-南通市图书馆

Autologous hematopoietic stem cell transplantation conditioning regimens and chimeric antigen receptor T cell therapy in various diseases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Transplantation 2024年第1期14卷 32-41页

作者： Shahzaib Maqbool Maryam Farhan Baloch Muhammad abdul khaliq Khan Azeem Khalid Kiran Naimat Department of Medicine Holy Family HospitalRawalpindi 46000Pakistan Department of Community Medicine Allama Iqbal Medical CollegeLahore 45000Pakistan Department of Community Dentistry Baqai Medical UniversityKarachi 43000Pakistan Department of Medicine Allama lqbal Medical CollegeLahore 45000Pakistan Department of MedicineLiaquat University of Medical and Health Sciences Karachi 43000Pakistan

Conditioning regimens employed in autologous stem cell transplantation have been proven useful in various hematological disorders and underlying malignancies;however,despite being efficacious in various instances,negative consequences have also been *** conditioning regimens were extracted from various literature searches from databases like PubMed,Google scholar,EMBASE,and *** regimens for each disease were compared by using various end points such as overall survival(OS),progression free survival(PFS),and leukemia free survival(LFS).Variables were presented on graphs and analyzed to conclude a more efficacious conditioning *** multiple myeloma,the most effective regimen was high dose melphalan(MEL)given at a dose of 200/mg/*** comparative results of acute myeloid leukemia were presented and the regimens that proved to be at an admirable position were busulfan(BU)+MEL regarding OS and BU+VP16 regarding *** case of acute lymphoblastic leukemia(ALL),BU,fludarabine,and etoposide(BuFluVP)conferred good disease control not only with a paramount improvement in survival rate but also low risk of ***,for ALL,chimeric antigen receptor(CAR)T cell therapy was preferred in the context of better OS and *** respect to Hodgkin’s lymphoma,mitoxantrone(MITO)/MEL overtook carmustine,VP16,cytarabine,and MEL in view of PFS and vice versa regarding ***-Hodgkin’s lymphoma patients were administered MITO(60 mg/m2)and MEL(180 mg/m2)which showed promising ***,amyloidosis was considered,and the regimen that proved to be competent was MEL 200(200 mg/m2).This review article demonstrates a comparison between various conditioning regimens employed in different diseases.

关键词： Conditioning regimens Multiple myeloma Lymphoma Hodgkin Non-Hodgkin Acute leukemia

Investigation of secondary phases and tensile strength of nitrogen-containing Alloy 718 weldment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2020年第9期27卷 1259-1268页

作者： Behrooz Nabavi Massoud Goodarzi abdul khaliq Khan School of Metallurgy and Materials Engineering Iran University of Science and TechnologyTehran ***Iran Department of Mechanical Engineering Manitoba Institute for MaterialsUniversity of ManitobaWinnipeg R3T 2N2Canada

The influence of nitrogen content on the precipitation of secondary phases and the tensile strength of Alloy 718 during gas tungstenarc welding was investigated. Various types of precipitates were characterized using scanning electron microscopy and transmission electronmicroscopy. The results showed that in the fusion zone, the volume fraction of Nb-rich phases such as Laves, (Nb,Ti)C, and δ phases, as wellas Ti-rich phases such as (Ti,Nb)CN and (Ti,Nb)N, increased with increase in the nitrogen content due to the microsegregation of Nb and Tiwithin interdendritic areas. Nitrogen was also found to decrease the size of γ′′ particles within γ dendrites. For precipitates in the partiallymelted zone, constitutional liquation was observed for both (Nb,Ti)C and (Ti,Nb)N particles. Based on the results of tensile tests, the weld containing0.015wt% nitrogen exhibited the highest ultimate tensile strength (UTS), whereas more addition of nitrogen led to a decrease in both theUTS and yield strength due to the increased content of brittle Laves phases and decreased size of γ′′.

关键词： nitrogen secondary phases gas tungsten arc welding tensile strength Alloy 718

A Split-Step Predictor-Corrector Method for Space-Fractional Reaction-Diffusion Equations with Nonhomogeneous Boundary Conditions

在线全文

学校读者我要写书评

暂无评论

Communications on Applied Mathematics and Computation 2019年第4期1卷 525-544页

作者： Kamran Kazmi abdul khaliq Department of Mathematics University of Wisconsin OshkoshOshkoshWI 54901USA Department of Mathematical Sciences and Center for Computational Sciences Middle Tennessee State UniversityMurfreesboroTN 37132USA

A split-step second-order predictor-corrector method for space-fractional reaction-diffusion equations with nonhomogeneous boundary conditions is presented and analyzed for the stability and *** matrix transfer technique is used for spatial discretization of the *** method is shown to be unconditionally stable and second-order *** experiments are performed to confirm the stability and secondorder convergence of the *** split-step predictor-corrector method is also compared with an IMEX predictor-corrector method which is found to incur oscillatory behavior for some time *** method is seen to produce reliable and oscillatioresults for any time step when implemented on numerical examples with nonsmooth initial *** also present a priori reliability constraint for the IMEX predictor-corrector method to avoid unwanted oscillations and show its validity numerically.

关键词： Fractional Laplacian Space-fractional reaction diffusion equations Non-homogeneous boundary conditions Matrix transfer technique Predictor-corrector method

Weed control through allelopathic crop water extracts and S-metolachlor in cotton

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Information Processing in Agriculture 2020年第1期7卷 165-172页

作者： Nadeem Iqbal abdul khaliq Zahid Ata Cheema School of Agriculture and Food Science University of QueenslandBrisbane 4072Australia Depatment of Agronomy University of AgricultureFaisalabad 38040Pakistan

Weeds are one of the most important biological constraint to cotton production,and result-ing in a yield losses of up to 90%.The evolution of hundreds of resistant weed species,the lack of new herbicide chemistries,and the increase in weed management costs are all mak-ing weed management more arduous for the ***,a field experiment was con-ducted to investigate the efficacy of allelopathic crop water extracts(ACWEs)alone and in combinaton with one third rate of S-metolachlor 717g ***-1for effective weed man-agement in *** treatments investigated were;weedy check,sorghum+brassica water extract(WE)at 1.5Lha 1,sorghum+sunflower WE at 1.5Lha-,sorghum+bras-sica+sunflower WE at 1.5Lha-1,sorghum+brassica WE at 15L ha-1+S-metolachlor at 717 g ***-l,sorghum+sunflower WE at 1.5L ha-1+S-metolachlor at 717 g ***-1,sor-ghum+brassica WE+sunflower WE at 1.5Lha-1+S-metolachlor at 717 gaiha-,and S-metolachlor at recommended rate of 2.15 kg *** revealed that pre-emergent application of sorghum+brassica water extract(WE)at 1.5L ha-1 was the best treatment in terms of effective dry biomass reduction(40%)of Trianthema portulacastrum and Cyperus rotundus,and increase in seed cotton yield(12%).The second best treatment was sorghum+sunflower WE at 1.5Lha-1+S-metolachlor at 717g ***-1 with yield increase of 11%over the weedy *** comparison,S-metolachlor at recommended rate 2.15kg ***-1 recorded only 4%decrease in weeds dry biomass reduction and 8%increase in seed cotton ***,it can be predicted that binary combinaton of sorghum and brassica WE at 1.5 Lha-1 or binary combination of sorghum+sunflower WE at 15Lha-1 with one third dose of S-metolachlor (717g aiha-l)can be used for effective weed management and increase in seed cotton ***,adoption of this technique will also reduce the herbicide application,which is not only benefcial for the ecosystem but,also minimize the evolution of herbicide-resistant weed species.

关键词： Allelopathy Chemical weed control Herbicide Weeds Biomass Seed cotton yield Environment

Technical crystallization for application in pharmaceutical material engineering:Review article

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Pharmaceutical Sciences 2015年第4期10卷 283-291页

作者： abdul khaliq El-Zhry El-Yafi Hind El-Zein Department of Pharmaceutical Technology Faculty of PharmacyDamascus UniversityDamascusSyria

In recent years,engineering the total morphology of pharmaceutical materials particles to desirable shape,size and surface area has long been actively increased because it has many advantages especially for improving physicochemical properties of Active Pharmaceutical Ingredients(APIs).This article therefore considers the potential utility of crystal engineering as a tool for controlling and designing properties of pharmaceutical solid particles in purpose to developing efficacious performance of solid dosage form,fundamentals of crystallization process,*** addition,understanding the relationship between molecular recognition,thermodynamic,and kinetics which controls the crystallization process so that it benefits in designing successful experiments to have desirable crystal habit for materials.

关键词： Crystallization Nucleation Crystal growth dispersion Thermodynamic

Weed growth, herbicide efficacy, and rice productivity in dry seeded paddy field under different wheat stubble management methods

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2019年第4期18卷 907-926页

作者： Muhammad Zia-Ul-Haq abdul khaliq Qiang Sheng Amar Matloob Saddam Hussain Saba Fatima Zeshan Aslam Department of Agronomy University of AgricultureFaisalabad Weed Research Laboratory College of Life Sciences Nanjing Agricultural University Department of Agronomy Muhammad Nawaz Shareef University of Agriculture Department of Economics National College of Business Administration and Economics Pesticide Residue Laboratory Kala Shah Kaku Institute of Soil Chemistry and Environmental Sciences Government of Punjab

To ascertain the influence of wheat stubble management options and chemical weed control methods on weed growth and productivity of dry direct-seeded fine rice, a two years' field study was undertaken at the Agronomic Research Farm, University of Agriculture, Faisalabad, Pakistan in 2013 and 2014. Different wheat stubble management methods, viz., incorporation, burning and retention were executed during seed-bed preparation. While, herbicide treatments comprised of a weed check, weed free, pendimethalin followed by tank mixture of fenoxaprop p-ethyl+ethoxysulfuron ethyl, and bispyribac sodium followed by tank mixture of fenoxaprop p-ethyl+ethoxysulfuron ethyl. Results revealed that weed control efficacy of both herbicide treatments ranged from 84 to 94%. Herbicide treatments significantly reduced weed density(88–90%) and dry weight(86–88%), while improved the rice growth attributes compared with weed check. Application of bispyribac sodium followed by tank mixture of fenoxaprop p-ethyl+ethoxysulfuron ethyl in stubble retention recorded 226 and 273% increase in kernel yield over weedy check in 2013 and 2014, respectively. In stubble incorporation, pendimethalin followed by tank mixture of fenoxaprop p-ethyl+ethoxysulfuron ethyl was more effective in increasing(256–293%) rice yields over weedy check. Among different treatment combinations, the maximum net benefits(1 397.49^(–1) 472.22 USD ha^(–1)), net returns(636–700 USD ha^(–1)), benefit cost ratio(1.77^(–1).83) and marginal rate of return(2 187–2 330%) were recorded with the application of bispyribac sodium followed by fenoxaprop p-ethyl+ethoxysulfuron ethyl in stubble retention. In crux, application of bispyribac sodium followed by tank mixture of fenoxaprop p-ethyl+ethoxysulfuron ethyl in stubble retention is efficient approach to control weeds, and get maximum rice productivity and net economic returns under dry seeded system.

关键词： herbicide mixture weedy check stubble management weeds density and dry weight DSR

Optical dromions for complex Ginzburg Landau model with nonlinear media

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics(A Journal of Chinese Universities) 2023年第1期38卷 111-125页

作者： Syed T.R.Rizvi Aly R.Seadawy Muhammad Younis S.O.Abbas abdul khaliq Department of Mathematics COMSATS University IslamabadLahore CampusPakistan Mathematics Department Faculty of ScienceTaibah UniversityAl-Madinah Al-Munawarah 41411Kingdom of Saudi Arabia Punjab University College of Information Technology University of the PunjabLahore Pakistan Mathematics Department Riphah Institute of Computing and Applied SciencesRiphah International UniversityLahorePakistan

This manuscript studies the optical dromions with beta derivative(BD)applied to the Complex Ginzburg Landau equation(CGLE)with Kerr law,parabolic law,cubic quintic septic law and quadratic cubic *** obtain bright dromians by using the sine-cosine method(SCM).We will also obtain domain walls with the assistance of Bernoulli equation approach(BEA).Constraint conditions are also listed.

关键词： CGLE optical dromians non-Kerr laws

A Biobank for Long-term and Sustainable Research in the Field of Congenital Heart Disease in Germany

在线全文

学校读者我要写书评

暂无评论

Genomics, Proteomics & Bioinformatics 2016年第4期14卷 181-190页

作者： Thomas Pickardt Eva Niggemeyer Ulrike M.M.Bauer Hashim abdul-khaliq Competence Network for Congenital Heart Defects Investigators National Register for Congenital Heart Defects 13353 BerlinGermany Saarland University Medical Center Department of Paediatrie Cardiology66421 HomburgGermany Competence Network for Congenital Heart Defects 13353 BerlinGermany

Congenital heart disease （CHD） is the most fi＇equent birth defect （0.8% 1% of all live births）. Due to the advance in prenatal and postnatal early diagnosis and treatment, more than 90% of these patients survive into adulthood today. However, several mid- and long-term morbidi- ties are dominating the follow-up of these patients. Due to the rarity and heterogeneity of the phenotypes of CHD, multicenter registry-based studies are required. The CHD-Biobank was established in 2009 with the aim to collect DNA from patients and their parents （trios） or fi＇om affected families, as well as cardiovascular tissues from patients undergoing corrective heart surgery for cardiovascular malformations. Clinical/phenotype data are matched to the International Paediatric and Congenital Cardiac Code （IPCCC） and the International Statistical Classification of Diseases and Related Health Problems 10th Revision （ICD-10）. The DNA collection currently comprises samples from approximately 4200 participants with a wide range of CHD phenotypes. The collection covers about 430 trios and 120 families with more than one affected member. The cardiac tissue collection comprises 1143 tissue samples [Yore 556 patients alter open heart surgery. The CHD-Biobank provides a comprehensive basis for research in the field of CHD with high standards of data privacy, IT management, and sample logistics.

关键词： Congenital heart defects Multi-center research Biorepository Genetic research DNA

Indirect Vector Control of Linear Induction Motors Using Space Vector Pulse Width Modulation

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2023年第3期74卷 6263-6287页

作者： Arjmand khaliq Syed abdul Rahman Kashif Fahad Ahmad Muhammad Anwar Qaisar Shaheen Rizwan Akhtar Muhammad Arif Shah Abdelzahir Abdelmaboud Electrical Engineering Department University of Engineering and TechnologyLahore54700Pakistan Department of Basic Sciences Deanship of Common First YearJouf UniversitySakakaAljouf72341Saudi Arabia Department of Information Science Division of Science and TechnologyUniversity of EducationLahore54000Pakistan Department of Computer Science and Information Technology The Islamia University of BahawalpurRahim Yar Khan Sub CampusPakistan Department of IT and Computer Science Pak-Austria Fachhochschule Institute of Applied Sciences and TechnologyHaripurPakistan Department of Information Systems King Khalid UniversityMuhayel Aseer61913Saudi Arabia

Vector control schemes have recently been used to drive linear induction motors(LIM)in high-performance *** trend promotes the development of precise and efficient control schemes for individual *** research aims to present a novel framework for speed and thrust force control of LIM using space vector pulse width modulation(SVPWM)*** framework under consideration is developed in four *** begin,MATLAB Simulink was used to develop a detailed mathematical and electromechanical *** research presents a modified SVPWM inverter control *** tuning the proportional-integral(PI)controller with a transfer function,optimized values for the PI controller are *** the subsystems mentioned above are integrated to create a robust simulation of the LIM’s precise speed and thrust force control *** reference speed values were chosen to evaluate the performance of the respective system,and the developed system’s response was verified using various data *** the low-speed range,a reference value of 10m/s is used,while a reference value of 100 m/s is used for the high-speed *** speed output response indicates that themotor reached reference speed in amatter of seconds,as the delay time is between 8 and 10 *** maximum amplitude of thrust achieved is less than 400N,demonstrating the controller’s capability to control a high-speed LIM with minimal thrust *** to the controlled speed range,the developed system is highly recommended for low-speed and high-speed and heavy-duty traction applications.

关键词： Space vector pulse width modulation linear induction motor proportional-integral controller indirect vector control electromechanical dynamic modeling