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COVID-19 and congenital heart disease:a case series of nine children

World Journal of Pediatrics 2021年第1期17卷 71-78页

作者： Elmira Haji Esmaeil Memar Babak Pourakbari mojtaba gorgi Meisam Sharifzadeh Ekbatani Amene Navaeian Mahmoud Khodabandeh Shima Mahmoudi Setareh Mamishi Pediatrics Center of Excellence Children's Medical CenterTehran University of Medical SciencesTehranIran Pediatric Infectious Disease Research Center Tehran University of Medical ScienceTehranIran Division of Pediatric Intensive Care Unit Pediatrics Center of ExcellenceChildren's Medical CenterTehran University of Medical SciencesTehranIran Department of Infectious Diseases Pediatrics Center of ExcellenceChildren's Medical CenterTehran University of Medical SciencesTehranIran

Background Coronavirus disease 2019(COVID-19)is the current pandemic disease without any vaccine or efficient treat-ment to rescue the *** diseases predispose the patients to a more severe disease and to a higher mortality ***,little evidence exists about COVID-19 outcomes in the pediatric population with congenital heart disease(CHD).Here,we report nine children with COVID-19 and concomitant *** Our study included nine children with COVID-19 and concomitant CHD who were admitted to Children Medical Center Hospital during March and April *** patients were classified based on the final outcome(death),and their clinical sign and symptoms,type of CHD,and drugs administered were *** Among the nine patients,two died and we compared different characteristics,laboratory results and clinical findings of these cases based on the *** deceased patients had severe types of CHD,worse arterial blood gases,severe clinical symptoms,higher mean level of partial thromboplastin time and C-reactive protein,and required more *** The present study showed that the general consideration of mild COVID-19 in children does not include patients with CHD and that it is necessary to pay greater attention to children with CHD to determine guidelines for treatment of COVID-19 in these *** to the scarcity of CHD and COVID-19,we reported only nine ***,further studies are highly required in this regard.

关键词： Congenital heart disease Coronavirus disease 2019 Pediatrics

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