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Decoding molecular mechanisms:brain aging and Alzheimer's disease

Neural Regeneration Research 2025年第8期20卷 2279-2299页

作者： Mahnoor Hayat Rafay Ali Syed Hammad Qaiser Mohammad Uzair Khalid Al-Regaiey Roaa Khallaf Lubna Abdullah mohammed Albassam Imdad Kaleem Xueyi Wang Ran Wang Mehwish SBhatti Shahid Bashir Atta-ur-Rahman School of Applied Biosciences(ASAB) National University of Sciences and Technology(NUST)IslamabadPakistan Department of Biotechnology Quaid-i-Azam UniversityIslamabadPakistan Department of Biological Sciences Faculty of Basic&Applied SciencesInternational Islamic University Islamabad(IIUI)IslamabadPakistan Department of Bioengineering King Fahd University of Petroleum and MineralsDhahranSaudi Arabia Department of Physiology College of MedicineKing Saud UniversityRiyadhSaudi Arabia Department of Neurology Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Mental Health Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Biosciences Commission on Science and Technology for Sustainable Development in the South(COMSATS University)IslamabadPakistan Department of Psychiatry The First Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Mental Health Institute of Hebei Medical University ShijiazhuangHebei ProvinceChina Department of Neurobiology and Behavior University of CaliforniaIrvineCAUSA Neuroscience Center King Fahad Specialist Hospital DammamDammamSaudi Arabia

The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for *** aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as Alzheimer's *** these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging *** these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect *** review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of Alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly Alzheimer's disease.

关键词： Alzheimer’s disease brain aging cognitive health dementia molecular mechanisms neuronal activity neuroplasticity neurotransmission

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Deflection behavior of a prestressed concrete beam reinforced with carbon fibers at elevated temperatures

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Frontiers of Structural and Civil Engineering 2019年第1期13卷 81-91页

作者： mohammed FARUQI mohammed Sheroz KHAN Department of Civil and Architectural Engineering Texas A&M University--KingsvilleTexasUSA

Fiber reinforced polymer(FRP) have unique advantages like high strength to weight ratio,excellent corrosion resistance,improving deformability and cost *** advantages have gained wide acceptance in civil engineering *** tendons for prestressing applications are emerging as one of the most promising technologies in the civil engineering ***,the behavior of such members under the influence of elevated temperatures is still *** knowledge and application of this could lead to a cost effective and practical considerations in fire safety ***,this study examines the deflection behavior of the carbon fiber reinforced polymer(CFRP) prestressed concrete beam at elevated *** this article,an analytical model is developed which integrates the temperature dependent changes of effective modulus of FRP in predicting the deflection behavior of CFRP prestressed concrete beams within the range of practical *** model is compared with a finite element mode (FEM) of a simply supported concrete beam prestressed with CFRP subjected to practical elevated *** addition,comparison is also made with an indirect reference to the real behavior of the *** results of the model correlated reasonably with the finite element model and the real ***,a practical application is provided.

关键词： FRP CFRP concrete elevated temperatures deflections prestress

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MULTIDIMENSIONAL RELAXATION APPROXIMATIONS FOR HYPERBOLIC SYSTEMS OF CONSERVATION LAWS

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Journal of Computational Mathematics 2007年第4期25卷 440-457页

作者： mohammed Seaid UniversitSt Kaiserslautern Fachbereich Mathematik 67663 Kaiserslautern Germany

We construct and implement a non-oscillatory relaxation scheme for multidimensional hyperbolic systems of conservation laws. The method transforms the nonlinear hyperbolic system to a semilinear model with a relaxation source term and linear characteristics which can be solved numerically without using either Riemann solver or linear iterations. To discretize the relaxation system we consider a high-resolution reconstruction in space and a TVD Runge-Kutta time integration. Detailed formulation of the scheme is given for problems in three space dimensions and numerical experiments are implemented in both scalar and system cases to show the effectiveness of the method.

关键词： Multidimensional hyperbolic systems Relaxation methods Non-oscillatory reconstructions Asymptotic-preserving schemes.

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Recent advances on flexible electrodes for Na-ion batteries and Li–S batteries

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Journal of Energy Chemistry 2019年第5期28卷 15-44页

作者： mohammed-Ibrahim Jamesh Department of Physics and Materials Science City University of Hong Kong Applied and Plasma Physics School of Physics (A28) University of Sydney CSIR-Central Electrochemical Research Institute-Chennai Unit CSIR Madras Complex

Flexible energy storage devices are essential for emerging flexible electronics. The existing state-of-the-art Li-ion batteries are slowly reaching their limitation in terms of cost and energy density. Hence, flexible Na-ion batteries (SIBs) with abundanee Na resources and Li-S batteries with high energy density become the alternative for the Li-ion batteries in future. This review summarizes the recent advances in the development of flexible electrode materials for SIBs with metallic matrix and carb on aceous matrix such as carb on nano-tubes, carbon nano-fiber, graphene, carbon cloth, carbon fiber cloth, and cotton textiles. Then, the potential prototype flexible full SIBs are discussed. Further, the recent progress in the development of flexible electrode materials for Li-S batteries based on carb on nano-fiber, carb on nano-tubes, graphene, and cotton textiles is reviewed. Moreover, the design strategies of suitable interlayer, separator, electrolyte, and electrodes to prevent the dissolution and shuttle effect of polysulfides in flexible Li-S batteries are provided. Finally some prospective investigation trends towards future research of flexible SIBs and Li-S batteries are also proposed and discussed. The scientific and engineering knowledge gained on flexible SIBs and Li-S batteries provides conceivable development for practical application in near future.

关键词： Na-ion batteries Lithium-sulfur batteries Flexible Free-standing High performance energy storage Long cycle life

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Adaptive neuro fuzzy inference system for predicting sub-daily Zenith Wet Delay

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Geodesy and Geodynamics 2022年第4期13卷 352-362页

作者： Jareer mohammed Civil Engineering Department Wasit UniversityKutIraq

In recent years,the focus of tropospheric studies has evolved to GNSS meteorology and weather *** Zenith Wet Delay(ZWD),which might be assembled to the Integrated Water Vapour(IWV),is an essential component of the tropospheric *** predicted the ZWD with the required level of accuracy is crucial for weather *** scope of this study is to use the adaptive neural fuzzy inference system(ANFIS)to predict the ZWD for the following six-hour epoch based exclusively on the present the ZWD *** was developed and verified using 505 geographically and internationally distributed stations which were used for training and testing from 2008 to *** was assessed based on two ***,the correlation coefficient(R)values were found to be more than 0.8 in 98%of the stations,including those with highest and lowest latitudes,and the remaining 2% of stations located in coastal ***,the Root Mean Square Error(RMSE)values of the differences between the pre-dicted and the actual ZWD were considered to be the more important finding of the *** is,99.21% of the 505 stations had the RMSE values equal to or less than 3 cm,with only 4 stations having the RMSE values higher(0.2 mm)than 3 *** the results of this study achieved the required degree of ac-curacy from the predicted ZWD to be utilized in weather forecasting,they may also be beneficial for GNSS meteorology.

关键词： ANFIS ZWD Weather forecasting GNSS meteorology

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Modeling the capability of penetrating a jammed crowd to eliminate freezing transition

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Chinese Physics B 2016年第5期25卷 65-72页

作者： mohammed Mahmod Shuaib College of Shari’a and Islamic Studies in Al Ahsaa Department of Computer Sciences Al-Imam Muhammad Ibn Saud Islamic University (IMSIU)

Frozen state from jammed state is one of the most interesting aspects produced when simulating the multidirectional pedestrian flow of high density crowds. Cases of real life situations for such a phenomenon are not exhaustively *** observations in the Hajj crowd show that freezing transition does not occur very often. On the contrary, penetrating a jammed crowd is a common aspect. We believe the kindness of pedestrians facing others whose walking is blocked is a main factor in eliminating the frozen state as well as in relieving the jammed state. We refine the social force model by incorporating a new social force to enable the simulated pedestrians to mimic the real behavior observed in the Hajj *** are performed to validate the work qualitatively.

关键词： multidirectional flow jamming transition pedestrian behavior social force

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Advanced Functional Electromagnetic Shielding Materials:A Review Based on Micro‑Nano Structure Interface Control of Biomass Cell Walls

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Nano-Micro Letters 2025年第1期17卷 98-134页

作者： Yang Shi Mingjun Wu Shengbo Ge Jianzhang Li Anoud Saud Alshammari Jing Luo mohammed A.Amin Hua Qiu Jinxuan Jiang Yazeed M.Asiri Runzhou Huang Hua Hou Zeinhom M.El‑Bahy Zhanhu Guo Chong Jia Kaimeng Xu Xiangmeng Chen Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources College of Materials Science and EngineeringNanjing Forestry UniversityNanjing 210037People’s Republic of China State Key Laboratory of Efficient Production of Forest Resourced Beijing Forestry UniversityQinghua East Road 35Haidian DistrictBeijing 100083People’s Republic of China Department of Physics Faculty of Sciences‑ArarNorthern Border UniversityArar 91431Saudi Arabia Department of Chemistry College of ScienceTaif UniversityP.O.Box 1109921944 TaifSaudi Arabia Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’anShaanxi 710072People’s Republic of China Integrated Composites Lab Department of Mechanical and Construction EngineeringNorthumbria UniversityNewcastle Upon Tyne NE18STUK College of Materials Science and Engineering Taiyuan University of Science and TechnologyTaiyuan 030024People’s Republic of China Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr CityCairo 11884Egypt Yunnan Provincial Key Laboratory of Wood Adhesives and Glued Products International Joint Research Center for Biomass MaterialsSouthwest Forestry UniversityKunming 650224People’s Republic of China School of Science Henan Agricultural UniversityZhengzhou 450002People’s Republic of China

Research efforts on electromagnetic interference(EMI)shielding materials have begun to converge on green and sustainable biomass *** materials offer numerous advantages such as being lightweight,porous,and *** to their porous nature,interfacial compatibility,and electrical conductivity,biomass materials hold significant potential as EMI shielding *** concerted efforts on the EMI shielding of biomass materials have been reported,this research area is still relatively new compared to traditional EMI shielding *** particular,a more comprehensive study and summary of the factors influencing biomass EMI shielding materials including the pore structure adjustment,preparation process,and micro-control would be *** preparation methods and characteristics of wood,bamboo,cellulose and lignin in EMI shielding field are critically discussed in this paper,and similar biomass EMI materials are summarized and *** composite methods and fillers of various biomass materials were *** paper also highlights the mechanism of EMI shielding as well as existing prospects and challenges for development trends in this field.

关键词： Biomass materials Electromagnetic interference shielding Micro-nano structure interface control Conductivity

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An Energy-Efficient Protocol Using an Objective Function & Random Search with Jumps forWSN

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Computers, Materials & Continua 2019年第3期58卷 603-624页

作者： mohammed Kaddi Khelifa Benahmed mohammed Omari Faculty of Technology University Tahri MohammedBechar08000Algeria Faculty of Exact Sciences University Tahri MohammedBechar08000Algeria LDDI Laboratory Math and CS DepartmentUniversity of AdrarAdrar01000Algeria.

Wireless Sensor Networks(WSNs)have hardware and software limitations and are deployed in hostile *** problem of energy consumption in WSNs has become a very important axis of *** obtain good performance in terms of the network lifetime,several routing protocols have been proposed in the *** routing is considered to be the most favorable approach in terms of energy *** is based on the concept parent-child hierarchy where the child nodes forward their messages to their parent,and then the parent node forwards them,directly or via other parent nodes,to the base station(sink).In this paper,we present a new Energy-Efficient clustering protocol for WSNs using an Objective Function and Random Search with Jumps(EEOFRSJ)in order to reduce sensor energy ***,the objective function is used to find an optimal cluster formation taking into account the ratio of the mean Euclidean distance of the nodes to their associated cluster heads(CH)and their residual ***,we find the best path to transmit data from the CHs nodes to the base station(BS)using a random search with *** simulated our proposed approach compared with the Energy-Efficient in WSNs using Fuzzy C-Means clustering(EEFCM)protocol using Matlab *** results have shown that our proposed protocol excels regarding energy consumption,resulting in network lifetime extension.

关键词： WSNs clustering energy consumption lifetime extension random search with jumps EEOFRSJ EEFCM.

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EECLP: AWireless Sensor Networks Energy Efficient Cross-Layer Protocol

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Computers, Materials & Continua 2024年第8期80卷 2611-2631页

作者： mohammed Kaddi mohammed Omari Moamen Alnatoor LDDI Laboratory University of AdrarAdrar01000Algeria Computer Science and Engineering Department School of EngineeringAmerican University of Ras Al KhaimahRas Al Khaimah72603United Arab Emirates

Recent advancements in wireless communications have allowed the birth of novel wireless sensor networks(WSN).A sensor network comprises several micro-sensors deployed randomly in an area of interest.A micro-sensor is provided with an energy resource to supply electricity to all of its ***,the disposed energy resource is limited and battery replacement is generally *** this restriction,the sensors must conserve energy to prolong their *** energy conservation strategies for WSNs have been presented in the literature,from the application to the physical *** of these solutions focus only on optimizing a single layer in terms of energy *** this research,a novel cross-layer technique for WSNs’effective energy usage is *** most energy consumption factors exist in the Medium Access Control(MAC)layer and network layer,our EECLP protocol(Energy Efficient Cross-Layer Protocol for Wireless Sensor Networks)integrates these two layers to satisfy energy efficiency *** gain access to the transmission channel,we implement a communication regime at the MAC layer based on CSMA/CA(Carrier Sense Multiple Access/Collision Avoidance)***,depending on the activity and a standby period,we employ the RTS/CTS(Request to Send/Clear to Send)method to prevent collisions and resolve hidden node concerns by utilizing the network allocation vector(NAV)to calculate the transmission *** a greedy strategy,we establish chains amongst cluster members to mitigate the issue of high energy consumption in routing *** objective function was utilized to determine the optimal cross-chain path based on the distances to the base station(BS)and residual energy(RE).The simulation,testing,and comparison of the proposed protocol to peer protocols have shown superior outcomes and a prolonged network *** the suggested protocol,the network lifetime increases by 10%compared to FAMACO(Fuzzy and Ant Col

关键词： WSN energy consumption MAC layer network layer EECLP energy-efficient lifespan

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Annealing Harmony Search Algorithm to Solve the Nurse Rostering Problem

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Computers, Materials & Continua 2022年第6期71卷 5545-5559页

作者： mohammed Hadwan Department of Information Technology College of ComputerQassim UniversityBuraydahSaudi Arabia Department of Computer Science College of Applied SciencesTaiz UniversityTaizYemen Intelligent Analytics Group(IAG) College of ComputerQassim UniversityBuraydahSaudi Arabia

A real-life problem is the rostering of nurses at *** is a famous nondeterministic,polynomial time(NP)-hard combinatorial optimization *** the real-world nurse rostering problem(NRP)constraints in distributing workload equally between available nurses is still a difficult task to *** international shortage of nurses,in addition to the spread of COVID-19,has made it more difficult to provide convenient rosters for *** on the literature,heuristic-based methods are the most commonly used methods to solve the NRP due to its computational complexity,especially for large ***-based algorithms in general have problems striking the balance between diversification and ***,this paper aims to introduce a novel metaheuristic hybridization that combines the enhanced harmony search algorithm(EHSA)with the simulated annealing(SA)algorithm called the annealing harmony search algorithm(AHSA).The AHSA is used to solve NRP from a Malaysian *** AHSA performance is compared to the EHSA,climbing harmony search algorithm(CHSA),deluge harmony search algorithm(DHSA),and harmony annealing search algorithm(HAS).The results show that the AHSA performs better than the other compared algorithms for all the tested instances where the best ever results reported for the UKMMC dataset.

关键词： Harmony search algorithm simulated annealing combinatorial optimization problems timetabling metaheuristic algorithms nurse rostering problems

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