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A novel polyherbal formulation containing thymoquinone attenuates carbon tetrachloride-induced hepatorenal injury in a rat model

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Asian Pacific Journal of Tropical Biomedicine 2020年第4期10卷 147-155页

作者： Aftab Ahmad mohammed f.abuzinadah Huda M.Alkreathy Hussam I.Kutbi Noor Ahmad Shaik Varish Ahmad Shakir Saleem Asif Husain Health Information Technology Department Faculty of Applied StudiesKing Abdulaziz UniversityJeddah-21589Kingdom of Saudi Arabia Department of Medical Laboratory Technology Faculty of Applied Medical SciencesKing Abdulaziz UniversityP.O.Box 80402 Jeddah-21589JeddahKingdom of Saudi Arabia Department of Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Pharmacy Practice Faculty of PharmacyKing Abdulaziz UniversityJeddahSaudi Arabia Department of Genetic Medicine Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Public Health College of Health SciencesSaudi Electronic UniversityRiyadhKingdom of Saudi Arabia Department of Pharmaceutical Chemistry School of Pharmaceutical Education and ResearchJamia Hamdard(Hamdard University)New Delhi110062India

Objective:To evaluate a novel polyherbal formulation(BSVT)containing the standardized extracts from the leaves of Boerhavia diffusa,Solidago virgaurea,Vitex negundo,and thymoquinone in CCl4 induced hepatorenal toxicity in ***:A total of 36 rats were divided into six groups including normal control,CCl4(2 mL/kg,i.p.),CCl4(2 mL/kg,i.p.)+Cystone?(750 mg/kg p.o.),CCl4(2 mL/kg,i.p.)+BSVT(25 mg/kg,p.o.),CCl4(2 mL/kg,i.p.)+BSVT(50 mg/kg,p.o.),and CCl4(2 mL/kg,i.p.)+BSVT(100 mg/kg,p.o.).All treatments were given for four *** levels of aspartate transaminase,alanine transaminase,alkaline phosphatase,cholesterol,total protein,serum urea,blood urea nitrogen and creatinine were *** dismutase,malondialdehyde,and glutathione peroxidase were evaluated in tissue *** histopathological study of liver and kidney tissues was also ***:Aspartate transaminase,alanine transaminase,alkaline phosphatase,cholesterol,serum urea,blood urea nitrogen and creatinine were significantly elevated(Pficantly decreased(Pformulation recovered these parameters towards a normal level in a dose-dependent ***:BSVT formulation ameliorates the hepatorenal toxicity in a dose-dependent ***,clinical studies are required to confirm its efficacy.

关键词： Boerhavia diffusa Solidago virgaurea Vitex negundo Thymoquinone Cystone^(█) Carbon tetrachloride Hepatorenal

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Stress distribution from railway track over geogrid reinforced ballast underlain by clay

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Earthquake Engineering and Engineering Vibration 2019年第1期18卷 77-93页

作者： mohammed Y.fattah Mahmood R.Mahmood mohammed f.Aswad Civil Engineering Department University of TechnologyBaghdad Iraq Civil Engineering Department University of TechnologyBaghdad IraqAssistant

Railway ballast forms a major component of a conventional rail track and is used to distribute the load to the subgrade, providing a smooth running surface for trains. It plays a significant role in providing support for the rail track base and distributing the load to the weaker layer underneath. Ballast also helps with drainage, which is an important factor for any type of transportation structure, including railroads. Over time, ballast progressively deforms and degrades under dynamic loading and loses its strength. In this study, extensive laboratory tests were conducted to investigate the effect of load amplitude, geogrid position, and number of geogrid layers, thickness of ballast layer and clay stiffness on the behavior of the reinforced ballast layer and induced strains in a geogrid. A half full-scale railway was constructed for carrying out the tests, which consisted of two rails 800 mm in length with three wooden sleepers(900 mm × 10 mm × 10 mm). Three ballast thicknesses of 200, 300 and 400 mm were used in the tests. The ballast was overlying 500 mm thickness clay in two states, soft and stiff. The tests were carried out with and without geogrid reinforcement; the tests were performed in a well-tied steel box of 1.5 m length ×1 m width ×1 m height. Laboratory tests were conducted to investigate the response of the ballast and the clay layers where the ballast was reinforced by a geogrid. Settlement in ballast and clay, soil pressure and pore water pressure induced in the clay were measured in reinforced and unreinforced ballast cases. It was concluded that the amount of settlement increased as the simulated train load amplitude increased, and there was a sharp increase in settlement up to cycle 500. After that, there was a gradual increase that leveled out between, 2500 to 4500 cycles depending on the frequency used. There was a slight increase in the induced settlement when the load amplitude increased from 0.5 to 1 ton but it was higher when the load am

关键词： ballast geogrid reinforcement clay stress pore water pressure dynamic load

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Review on nanocomposites fabricated by mechanical alloying

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International Journal of Minerals,Metallurgy and Materials 2019年第9期26卷 1047-1058页

作者： mohammed A. Taha Rasha A. Youness M.f. Zawrah Solid State Physics Department National Research CentreEl Buhouth St.Dokki 12622CairoEgypt Spectroscopy Department National Research CentreEl Buhouth St.Dokki 12622CairoEgypt Refractories Ceramics and Building Material DepartmentNational Research CentreEl Buhouth St.Dokki 12622CairoEgypt

Composites are composed of multiphase materials, where each phase has specific properties that differ from those of the other phases which can effect on the whole properties of composite. Nanocomposites are class of materials that contain at least one phase in the nanometric size range and can be produced by any suitable technique for preparing nanomaterials. Composites are an interesting class of materials that have recently been used in numerous applications, including structural, biomedical, electronics, and environmental applications. In composites, reinforcements might be fibers, particulates, or whiskers. Mechanical alloying(MA) is a promising technique for producing nanocomposite materials that are difficult or impossible to prepare via conventional techniques. In this review, we provide an overview of nanocomposites prepared by the MA process. The mechanism of milling and other milling parameters are overviewed, and insights into sintering categories and parameters are also presented.

关键词： nanocomposites mechanical alloying fabrication sintering

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On-line CO,CO_2 emissions evaluation and(benzene, toluene, xylene) determination from experimental burn of tropical biomass

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Journal of Environmental Sciences 2015年第7期27卷 239-244页

作者： mohammed f.Tawfiq Mohamed Kheireddine Aroua Nik Meriam Nik Sulaiman Chemical Engineering Department Faculty of Engineering University of Malaya

Atmospheric pollution and global warming issues are increasingly becoming major environmental concerns. fire is one of the significant sources of pollutant gases released into the atmosphere; and tropical biomass fires, which are of particular interest in this study,contribute greatly to the global budget of CO and CO2. This pioneer research simulates the natural biomass burning strategy in Malaysia using an experimental burning facility. The investigation was conducted on the emissions（CO2, CO, and Benzene, Toluene, Ethylbenzene,Xylenes（BTEX）） from ten tropical biomass species. The selected species represent the major tropical forests that are frequently subjected to dry forest fire incidents. An experimental burning facility equipped with an on-line gas analyzer was employed to determine the burning emissions. The major emission factors were found to vary among the species, and the specific results were as follows. The moisture content of a particular biomass greatly influenced its emission pattern. The smoke analysis results revealed the existence of BTEX,which were sampled from a combustion chamber by enrichment traps aided with a universal gas sampler. The BTEX were determined by organic solvent extraction followed by GC/MS quantification, the results of which suggested that the biomass burning emission factor contributed significant amounts of benzene, toluene, and m,p-xylene. The modified combustion efficiency（MCE） changed in response to changes in the sample moisture ***, this study concluded that the emission of some pollutants mainly depends on the burning phase and sample moisture content of the biomass.

关键词： Emission Biomass Experimental BTEX CO CO2 GG/MS

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Highlights in pathogenesis of vitiligo

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World Journal of Clinical Cases 2015年第3期3卷 221-230页

作者： Ghada f mohammed Amal Hussein Gomaa mohammed Saleh Al-Dhubaibi Department of Dermatology and Venereology Faculty of Medicine Suez Canal University Department of Dermatology Faculty of Medicine Qassim University

Vitiligo is a common pigmentary disorder. Many studies across decades and all over the world have attempted to illustrate the pathogenesis behind it; however, the pathogenesis of vitiligo remains elusive. This review article, we present the findings behind the most and updated theories behind this psychologically debilitating and disfiguring disease. The discussion begun with the role of genetic predisposition followed by neural theory first proposed in the 1950 s. Wehighlight the autoimmune hypothesis, followed by the reactive oxygen species model, zinc-α2-glycoprotein deficiency hypothesis, viral theory, intrinsic theory and biochemical, molecular and cellular alterations accounting for loss of functioning melanocytes in vitiligo. Many theories were elaborated to clarify vitiligo pathogenesis. It is a multifactorial disease involving the interplay of several factors. future research is needed to clarify the interaction of these factors for better understanding of vitiligo pathogenesis and subsequent successful treatment.

关键词： Etiopathogenesis Pigmentary disorder Non-segmental vitiligo Segmental vitiligo Vitiligo

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Trace-element geochemistry and S–O isotopes in the fluorite-barite mineralization of Merguechoum,Moroccan eastern Meseta:insights into ore genesis to the Pangea rifting

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Acta Geochimica 2023年第3期42卷 435-452页

作者： mohammed Cherai Larbi Rddad fouad Talbi Benjamin f.Walter faculte´des Sciences Laboratoire de GeosciencesGeo-Environnement et Prospection Miniere et HydriqueBP 71760000 OujdaMaroc Earth and Planetary Science Division Physical Science DepartmentKingsborough Community College of the City University of New York(CUNY)2001 Oriental BoulevardBrooklynNY 11235–2398USA Chair of Economic Geology and Geochemistry Karlsruhe Institute of Technology(KIT)Adenauerring 20B76131 KarlsruheGermany Laboratory for Environmental and Raw Material Analyses(LERA) Adenauerring 20B76131 KarlsruheGermany

The Merguechoum fluorite-barite mineralization,located in the Eastern Meseta of Morocco,is hosted in the Late Hercynian *** ore consists of fine crystals of fluorite 1,massive barite 1,euhedral crystals of fluorite 2,and barite 2 with calcite and minor quartz and *** Merguechoum ore deposits have never been *** study was the first contribution that studied the genesis of fluorite and *** ore occurs as dissemination within granite intrusion and also fills the NE-SWtrending meter-sized fractures and *** values of the total Rare Earth Elements and Yttrium(REY)and the ratios of LREY/HREY,Y/Ho,Tb/Ca,and Tb/La indicate that the Merguechoum fluorite precipitated from hydrothermal fluids,likely basinal brines,which interacted with the Hercynian *** REY data indicate that the ore-forming fluids of the early stage have intensely interacted with the Hercynian granite compared to those of the late ore *** gradual decrease in the europium(Eu/Eu^(*)),yttrium(Y/Y^(*)),and cerium(Ce/Ce^(*))anomalies and a low concentration ofΣREY observed in the second ore stage compared to the first ore stage suggest an increase in p H and fO_(2)and by inference a decrease in temperature during the evolution of the hydrothermal *** evolution could be explained by fluid mixing between the ascending basinal hydrothermal fluids and the diluted sulfate-rich meteoric water barite separates from selected samples reveal that the dissolved sulfates(SO_(4)^(2-))were derived from Permian–Triassic sulfates and/or coeval poreseawater *** proposed fluid mixing triggered the precipitation of an early-stage f-Ba assemblage followed by the second-stage f-Ba *** fieldwork,REY inventories,and isotope data point to the ore genesis during the Permian–Triassic extensional tectonic activity concerning the Pangea *** extensional tectonic environment is likely the driving force that mobilized a large amount of the ore

关键词： fluorite-barite veins Geochemistry of REY and trace elements O–S isotopes Late hercynian granite Pangea rifting Merguechoum Eastern Meseta of Moroccan

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flow Management Mechanism in Software-Defined Network

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Computers, Materials & Continua 2022年第1期70卷 1437-1459页

作者： Eugene Tan Yung-Wey Chong mohammed f.R.Anbar National Advanced IPv6 Centre Universiti Sains MalaysiaUSMPenangMalaysia

Software-defined networking(SDN)is a paradigm shift in modern ***,centralised controller architecture in SDNimposed flow setup overhead issue as the control plane handles all flows regardless of size and *** frameworks strictly reduce control plane overhead and it does not focus on rule placement of the flows ***,existing frameworks do not focus on managing elephant flows like ***,the proposed mechanism will use the flow statistics gathering method such as random packet sampling to determine elephant flow and microflow via a predefined *** mechanism will ensure that the control plane works at an optimum workload because the controller only manages elephant flows via reactive routing and rule placement *** routing has reduced link bandwidth usage below the pre-defined ***,rule placement has increased average throughput and total transfer to 238%.Meanwhile,the data plane switches will be able to forward microflows via multipath wildcard routing without invoking controller in greater responding time by 85 ms faster in two Transmission Control Protocol(TCP)traffic and achieved 11%and 12%higher total transfer size and throughput ***,the controller’s workload reduced significantly to 48%in two TCP traffic.

关键词： Software-defined network controller flow management

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Entropy and Entanglement in Master Equation of Effective Hamiltonian for Jaynes-Cummings Model

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Communications in Theoretical Physics 2009年第4期51卷 723-728页

作者： H.A.Hessian f.A.mohammed A.-B.A.Mohamed faculty of Science Assiut University

In this paper, we analytically solve the master equation for Jaynes-Cummings model in the dispersive regime including phase damping and the field is assumed to be initially in a superposition of coherent states. Using an established entanglement measure based on the negativity of the eigenvalues of the partially transposed density matrix we find a very strong sensitivity of the maximally generated entanglement to the amount of phase damping. Qualitatively this behavior is also reflected in alternative entanglement measures, but the quantitative agreement between different measures depends on the chosen noise model The phase decoherence for this model results in monotonic increase in the total entropy while the atomic sub-entropy keeps its periodic behaviour without any effect.

关键词： entanglement phase damping master equation superposition state

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Efficient Image Captioning Based on Vision Transformer Models

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Computers, Materials & Continua 2022年第10期73卷 1483-1500页

作者： Samar Elbedwehy T.Medhat Taher Hamza mohammed f.Alrahmawy Department of Data Science Faculty of Artificial IntelligenceKafrelsheikh UniversityEgypt Department of Electrical Engineering Faculty of EngineeringKafrelsheikh UniversityEgypt Department of Computer Science Faculty of Computer and Information ScienceMansouraEgypt

Image captioning is an emerging field in machine *** refers to the ability to automatically generate a syntactically and semantically meaningful sentence that describes the content of an *** captioning requires a complex machine learning process as it involves two sub models:a vision sub-model for extracting object features and a language sub-model that use the extracted features to generate meaningful ***-based vision transformers models have a great impact in vision field *** this paper,we studied the effect of using the vision transformers on the image captioning process by evaluating the use of four different vision transformer models for the vision sub-models of the image captioning The first vision transformers used is DINO(self-distillation with no labels).The second is PVT(Pyramid Vision Transformer)which is a vision transformer that is not using convolutional *** third is XCIT(cross-Covariance Image Transformer)which changes the operation in self-attention by focusing on feature dimension instead of token *** last one is SWIN(Shifted windows),it is a vision transformer which,unlike the other transformers,uses shifted-window in splitting the *** a deeper evaluation,the four mentioned vision transformers have been tested with their different versions and different configuration,we evaluate the use of DINO model with five different backbones,PVT with two versions:PVT_v1and PVT_v2,one model of XCIT,SWIN *** results show the high effectiveness of using SWIN-transformer within the proposed image captioning model with regard to the other models.

关键词： Image captioning sequence-to-sequence self-distillation transformer convolutional layer

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fractographic analysis of the overload effect on fatigue crack growth in 2024-T3 and 7075-T6 Al alloys

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International Journal of Minerals,Metallurgy and Materials 2020年第1期27卷 83-90页

作者： A.Albedah B.Bachir Bouiadjra S.M.A.K.mohammed f.Benyahia Mechanical Engineering Department College of EngineeringKing Saud UniversityP.O.Box 800Riyadh 11421Saudi Arabia LMPM Department of Mechanical EngineeringUniversity of Sidi Bel AbbesBP 89CitéBen M’hidiSidi Bel Abbes 22000Algeria Department of Mechanical and Industrial Engineering Ryerson UniversityTorontoOntario M5B 2K3Canada

The effect of single overload on the fatigue crack growth in 2024-T3 and 7075-T6 Al alloys was *** tests under constantamplitude loading with overload peak were carried out on V-notched *** analysis was used as a principal approach to explain the crack growth retardation due to the *** electron microscopy(SEM)analyses were conducted on the fractured surface of failed specimens to study the retardation *** obtained results show that the overload application generates a plastic zone in both aluminum *** generated plastic zone is three times larger in the case of 2024-T3 compared to 7075-T6,and thus,a significant crack retardation was induced for *** retardation effect due to the overload for 2024-T3 and 7075-T6 lasted for about 10 mm and 1 mm,respectively,from the point of overload application.

关键词： fatigue crack growth overload retardation fractography crack tip plasticity

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